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2026 Journal Article Selective and Efficient Functionalization of P22 Virus-Like Particles Using an Asparaginyl LigaseHarding, Maxim D., Jackson, Mark A., Yap, Kuok, Huda, Pie, Craik, David J., Sainsbury, Frank and Lawrence, Nicole (2026). Selective and Efficient Functionalization of P22 Virus-Like Particles Using an Asparaginyl Ligase. Bioconjugate Chemistry. doi: 10.1021/acs.bioconjchem.6c00356 |
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2026 Journal Article Direct Heterologous Expression of Cyclic Conotoxin [G22N]Vc1.1 in YeastXie, Jing, Yap, Kuok, Wang, Conan K., Durek, Thomas and Craik, David J. (2026). Direct Heterologous Expression of Cyclic Conotoxin [G22N]Vc1.1 in Yeast. ACS Chemical Biology, 21 (9), 2394-2403. doi: 10.1021/acschembio.6c00509 |
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2026 Journal Article Cofilin hyperphosphorylation triggers TDP-43 pathology in sporadic amyotrophic lateral sclerosisJagaraj, Cyril Jones, Saravanabavan, Sayanthooran, Parakh, Sonam, Jayakumar, Mrithulabashini, Kashani, Sara Assar, Shadfar, Sina, Mehta, Prachi, Gautam, Shashi, Farzana, Fabiha, Suchowerska, Alexandra K, Yap, Kuok, Vidal, Marta, Ragagnin, Audrey M G, Jamali, Md Shafi, Yang, Shu, Fath, Thomas, Craik, David and Atkin, Julie D (2026). Cofilin hyperphosphorylation triggers TDP-43 pathology in sporadic amyotrophic lateral sclerosis. Brain awag096. doi: 10.1093/brain/awag096 |
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2025 Journal Article Where have you been? Backtracking microplastic to its source using the biomolecular composition of the ecocoronaDawson, Amanda L., Bose, Utpal, Escobar-Correas, Sophia, Yap, Kuok, Craik, David J. and Pegg, Cassandra L. (2025). Where have you been? Backtracking microplastic to its source using the biomolecular composition of the ecocorona. Environmental Science and Technology, 59 (41), 22227-22238. doi: 10.1021/acs.est.5c09277 |
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2025 Journal Article Mixed-chirality prohibitin peptide: D-(RLARLAR)2 enhances stability and in vivo effects on obesityChan, Lai Yue, Weger, Benjamin D., Weger, Meltem, Du, Junqiao, Lawrence, Nicole, Cardoso, Marlon H., de Rezende, Samilla B., Muller, Jéssica A.I., Yap, Kuok, Tse, Brian W−C., Sokolowski, Kamil A., Sullivan, Robert K.P., Gunter, Jennifer, Franco, Octávio L., Gachon, Frédéric and Craik, David J. (2025). Mixed-chirality prohibitin peptide: D-(RLARLAR)2 enhances stability and in vivo effects on obesity. Journal of the American Chemical Society, 147 (28), 24628-24642. doi: 10.1021/jacs.5c05536 |
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2025 Journal Article High-throughput enrichment of functional disulfide-rich peptides by droplet microfluidicsXie, Jing, Yap, Kuok, de Veer, Simon J., Edwardraja, Selvakumar, Durek, Thomas, Trau, Matt, Craik, David J. and Wang, Conan K. (2025). High-throughput enrichment of functional disulfide-rich peptides by droplet microfluidics. Lab on a Chip, 25 (14), 3525-3536. doi: 10.1039/d5lc00261c |
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2025 Journal Article Exploring use of a protein cage system for producing bioactive peptides in Escherichia coliHarding, Maxim D., Jackson, Mark A., Gilding, Edward K., Yap, Kuok, Craik, David J., Sainsbury, Frank and Lawrence, Nicole (2025). Exploring use of a protein cage system for producing bioactive peptides in Escherichia coli. Microbial Biotechnology, 18 (6) e70158, 1-14. doi: 10.1111/1751-7915.70158 |
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2025 Journal Article Anticoagulation during Extracorporeal Membrane Oxygenation (ECMO): A Selective Inhibitor of Activated Factor XII Compared to Heparin in an Ex Vivo ModelGandini, Lucia, de Veer, Simon J., Chan, Chris H. H., Passmore, Margaret R., Liu, Keibun, Lundon, Brooke, Rachakonda, Reema, White, Nicole, Rhodes, Madeleine, Shanahan, Emma, Yap, Kuok, See Hoe, Louise E., Semenzin, Clayton, Li Bassi, Gianluigi, Fraser, John F., Craik, David J. and Suen, Jacky Y. (2025). Anticoagulation during Extracorporeal Membrane Oxygenation (ECMO): A Selective Inhibitor of Activated Factor XII Compared to Heparin in an Ex Vivo Model. ACS Pharmacology & Translational Science, 8 (5), 1260-1269. doi: 10.1021/acsptsci.4c00352 |
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2025 Conference Publication Butterfly pea’s hidden treasure: Toxicity guided identification of bioactive compoundsShambhawi, Chan, Lai Yue, Yap, Kuok and Craik, David J. (2025). Butterfly pea’s hidden treasure: Toxicity guided identification of bioactive compounds. 5th TropAg Conference, Brisbane, QLD, Australia, 11-13 November 2025. |
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2025 Journal Article Yeast as a tool for exploring disulfide-rich peptidesYap, Kuok, Porth, Owen T, Xie, Jing, Wang, Conan K, Durek, Thomas, Wittrup, K Dane and Craik, David J (2025). Yeast as a tool for exploring disulfide-rich peptides. FEMS Yeast Research, 25 foaf069. doi: 10.1093/femsyr/foaf069 |
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2024 Journal Article Hijacking of N-fixing legume albumin-1 genes enables the cyclization and stabilization of defense peptidesGilding, Edward K., Jackson, Mark A., Nguyen, Linh T. T., Hamilton, Brett R., Farquharson, Katherine A., Ho, Wing L., Yap, Kuok, Hogg, Carolyn J., Belov, Katherine and Craik, David J. (2024). Hijacking of N-fixing legume albumin-1 genes enables the cyclization and stabilization of defense peptides. Nature Communications, 15 (1) 6565, 6565. doi: 10.1038/s41467-024-50742-x |
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2024 Conference Publication Site-directed scanning mutagenesis reveals specific residues that enhance both the enduring stability and insecticidal efficacy of the cyclotide kalata B1Huang, Yen-Hua, Jiang, Zhihao, Yap, Kuok, Bigot, Aurelien, Kaas, Quentin, Wang, Conan and Craik, David (2024). Site-directed scanning mutagenesis reveals specific residues that enhance both the enduring stability and insecticidal efficacy of the cyclotide kalata B1. 37th European Peptide Symposium 14th International Peptide Symposium, Florence, Italy, 25-29 August 2024. Oxford, United Kingdom: John Wiley & Sons. |
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2024 Journal Article Proximity labelling confirms the involvement of papain-like cysteine proteases and chaperones in cyclotide biosynthesisLee, Meng-Han, Jackson, Mark A., Rehm, Fabian B. H., Barkauskas, Deborah S., Ho, Wing L., Yap, Kuok, Craik, David J. and Gilding, Edward K. (2024). Proximity labelling confirms the involvement of papain-like cysteine proteases and chaperones in cyclotide biosynthesis. Plant Molecular Biology Reporter, 42 (3), 611-623. doi: 10.1007/s11105-024-01462-5 |
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2024 Journal Article Scanning mutagenesis identifies residues that improve the long-term stability and insecticidal activity of cyclotide kalata B1Huang, Yen-Hua, Jiang, Zhihao, Du, Qingdan, Yap, Kuok, Bigot, Aurélien, Kaas, Quentin, Wang, Conan K. and Craik, David J. (2024). Scanning mutagenesis identifies residues that improve the long-term stability and insecticidal activity of cyclotide kalata B1. Journal of Biological Chemistry, 300 (3) 105682, 105682. doi: 10.1016/j.jbc.2024.105682 |
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2023 Journal Article Nematicidal activity of cyclotides: toxicity against Caenorhabditis elegansBajpai, Abhishek, Jackson, Mark A., Huang, Yen-Hua, Yap, Kuok, Du, Qingdan, Chau, Tevin Chui-Ying, Craik, David J. and Gilding, Edward K. (2023). Nematicidal activity of cyclotides: toxicity against Caenorhabditis elegans. Journal of Natural Products, 86 (5), 1222-1229. doi: 10.1021/acs.jnatprod.2c01124 |
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2023 Journal Article Plant-based production of an orally active cyclotide for the treatment of multiple sclerosisJackson, Mark A., Xie, Jing, Nguyen, Linh T. T., Wang, Xiaohan, Yap, Kuok, Harvey, Peta J., Gilding, Edward K. and Craik, David J. (2023). Plant-based production of an orally active cyclotide for the treatment of multiple sclerosis. Transgenic Research, 32 (1-2), 121-133. doi: 10.1007/s11248-023-00341-1 |
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2023 Journal Article Novel constituents of Salvia hispanica L. (chia) nutlet mucilage and the improved in vitro fermentation of nutlets when groundAng, Main Ern, Cowley, James M., Yap, Kuok, Hahn, Michael G., Mikkelsen, Deirdre, Tucker, Matthew R., Williams, Barbara A. and Burton, Rachel A. (2023). Novel constituents of Salvia hispanica L. (chia) nutlet mucilage and the improved in vitro fermentation of nutlets when ground. Food and Function, 14 (3), 1401-1414. doi: 10.1039/d2fo03002k |
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2022 Journal Article Neurotoxic and cytotoxic peptides underlie the painful stings of the tree nettle Urtica feroxXie, Jing, Robinson, Samuel D., Gilding, Edward K., Jami, Sina, Deuis, Jennifer R., Rehm, Fabian B.H., Yap, Kuok, Ragnarsson, Lotten, Chan, Lai Yue, Hamilton, Brett R., Harvey, Peta J., Craik, David J., Vetter, Irina and Durek, Thomas (2022). Neurotoxic and cytotoxic peptides underlie the painful stings of the tree nettle Urtica ferox. Journal of Biological Chemistry, 298 (8) 102218, 1-12. doi: 10.1016/j.jbc.2022.102218 |
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2022 Journal Article Cystine knot peptides with tuneable activity and mechanismLi, Choi Yi, Rehm, Fabian B. H., Yap, Kuok, Zdenek, Christina N., Harding, Maxim D., Fry, Bryan G., Durek, Thomas, Craik, David J. and Veer, Simon J. (2022). Cystine knot peptides with tuneable activity and mechanism. Angewandte Chemie, 61 (19) e202200951, e202200951. doi: 10.1002/ange.202200951 |
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2021 Journal Article Enzymatic C-terminal protein engineering with aminesRehm, Fabian B. H., Tyler, Tristan J., Yap, Kuok, de Veer, Simon J., Craik, David J. and Durek, Thomas (2021). Enzymatic C-terminal protein engineering with amines. Journal of the American Chemical Society, 143 (46) jacs.1c08976, 19498-19504. doi: 10.1021/jacs.1c08976 |
