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2021

Journal Article

Evaluation of efficient non-reducing enzymatic and chemical ligation strategies for complex disulfide-rich peptides

Tran, Hue N. T., Tran, Poanna, Deuis, Jennifer R., McMahon, Kirsten L., Yap, Kuok, Craik, David J., Vetter, Irina and Schroeder, Christina I. (2021). Evaluation of efficient non-reducing enzymatic and chemical ligation strategies for complex disulfide-rich peptides. Bioconjugate Chemistry, 32 (11) acs.bioconjchem.1c00452, 2407-2419. doi: 10.1021/acs.bioconjchem.1c00452

Evaluation of efficient non-reducing enzymatic and chemical ligation strategies for complex disulfide-rich peptides

2021

Journal Article

Asparaginyl ligases: new enzymes for the protein engineer's toolbox

Rehm, Fabian B. H., Tyler, Tristan J., Xie, Jing, Yap, Kuok, Durek, Thomas and Craik, David J. (2021). Asparaginyl ligases: new enzymes for the protein engineer's toolbox. ChemBioChem, 22 (12), 2079-2086. doi: 10.1002/cbic.202100071

Asparaginyl ligases: new enzymes for the protein engineer's toolbox

2021

Journal Article

Yeast-based bioproduction of disulfide-rich peptides and their cyclization via asparaginyl endopeptidases

Yap, Kuok, Du, Junqiao, Rehm, Fabian B. H., Tang, Shyn Ric, Zhou, Yan, Xie, Jing, Wang, Conan K., de Veer, Simon J., Lua, Linda H. L., Durek, Thomas and Craik, David J. (2021). Yeast-based bioproduction of disulfide-rich peptides and their cyclization via asparaginyl endopeptidases. Nature Protocols, 16 (3), 1-23. doi: 10.1038/s41596-020-00483-0

Yeast-based bioproduction of disulfide-rich peptides and their cyclization via asparaginyl endopeptidases

2020

Journal Article

Improved asparaginyl‐ligase‐catalyzed transpeptidation via selective nucleophile quenching

Rehm, Fabian B. H., Tyler, Tristan J., Yap, Kuok, Durek, Thomas and Craik, David J. (2020). Improved asparaginyl‐ligase‐catalyzed transpeptidation via selective nucleophile quenching. Angewandte Chemie, 133 (8) ange.202013584, 4050-4054. doi: 10.1002/ange.202013584

Improved asparaginyl‐ligase‐catalyzed transpeptidation via selective nucleophile quenching

2020

Journal Article

Production of a structurally validated cyclotide in rice suspension cells is enabled by a supporting biosynthetic enzyme

Qu, Haiou, Jackson, Mark A., Yap, Kuok, Harvey, Peta J., Gilding, Edward K. and Craik, David J. (2020). Production of a structurally validated cyclotide in rice suspension cells is enabled by a supporting biosynthetic enzyme. Planta, 252 (6) 97, 97. doi: 10.1007/s00425-020-03505-z

Production of a structurally validated cyclotide in rice suspension cells is enabled by a supporting biosynthetic enzyme

2020

Journal Article

Neurotoxic peptides from the venom of the giant Australian stinging tree

Gilding, Edward K., Jami, Sina, Deuis, Jennifer R., Israel, Mathilde R., Harvey, Peta J., Poth, Aaron G., Rehm, Fabian B. H., Stow, Jennifer L., Robinson, Samuel D., Yap, Kuok, Brown, Darren L., Hamilton, Brett R., Andersson, David, Craik, David J., Vetter, Irina and Durek, Thomas (2020). Neurotoxic peptides from the venom of the giant Australian stinging tree. Science Advances, 6 (38) eabb8828, 1-10. doi: 10.1126/sciadv.abb8828

Neurotoxic peptides from the venom of the giant Australian stinging tree

2020

Journal Article

An environmentally sustainable biomimetic production of cyclic disulfide-rich peptides

Yap, Kuok, Du, Junqiao, Looi, Fong Yang, Tang, Shyn Ric, de Veer, Simon J., Bony, Anuja R., Rehm, Fabian B. H., Xie, Jing, Chan, Lai Yue, Wang, Conan K., Adams, David J., Lua, Linda H. L., Durek, Thomas and Craik, David J. (2020). An environmentally sustainable biomimetic production of cyclic disulfide-rich peptides. Green Chemistry, 22 (15), 5002-5016. doi: 10.1039/d0gc01366h

An environmentally sustainable biomimetic production of cyclic disulfide-rich peptides

2020

Journal Article

Inside Cover: Application and Structural Analysis of Triazole‐Bridged Disulfide Mimetics in Cyclic Peptides (Angew. Chem. Int. Ed. 28/2020)

White, Andrew M., Veer, Simon J., Wu, Guojie, Harvey, Peta J., Yap, Kuok, King, Gordon J., Swedberg, Joakim E., Wang, Conan K., Law, Ruby H. P., Durek, Thomas and Craik, David J. (2020). Inside Cover: Application and Structural Analysis of Triazole‐Bridged Disulfide Mimetics in Cyclic Peptides (Angew. Chem. Int. Ed. 28/2020). Angewandte Chemie International Edition, 59 (28), 11162-11162. doi: 10.1002/anie.202006713

Inside Cover: Application and Structural Analysis of Triazole‐Bridged Disulfide Mimetics in Cyclic Peptides (Angew. Chem. Int. Ed. 28/2020)

2020

Journal Article

Innentitelbild: Application and Structural Analysis of Triazole‐Bridged Disulfide Mimetics in Cyclic Peptides (Angew. Chem. 28/2020)

White, Andrew M., Veer, Simon J., Wu, Guojie, Harvey, Peta J., Yap, Kuok, King, Gordon J., Swedberg, Joakim E., Wang, Conan K., Law, Ruby H. P., Durek, Thomas and Craik, David J. (2020). Innentitelbild: Application and Structural Analysis of Triazole‐Bridged Disulfide Mimetics in Cyclic Peptides (Angew. Chem. 28/2020). Angewandte Chemie, 132 (28), 11258-11258. doi: 10.1002/ange.202006713

Innentitelbild: Application and Structural Analysis of Triazole‐Bridged Disulfide Mimetics in Cyclic Peptides (Angew. Chem. 28/2020)

2020

Journal Article

Application and structural analysis of triazole‐bridged disulfide mimetics in cyclic peptides

White, Andrew M., Veer, Simon J., Wu, Guojie, Harvey, Peta J., Yap, Kuok, King, Gordon J., Swedberg, Joakim E., Wang, Conan K., Law, Ruby H. P., Durek, Thomas and Craik, David J. (2020). Application and structural analysis of triazole‐bridged disulfide mimetics in cyclic peptides. Angewandte Chemie International Edition, 132 (28) anie.202003435, 11369-11373. doi: 10.1002/anie.202003435

Application and structural analysis of triazole‐bridged disulfide mimetics in cyclic peptides

Featured

2020

Journal Article

A bifunctional asparaginyl endopeptidase efficiently catalyzes both cleavage and cyclization of cyclic trypsin inhibitors

Du, Junqiao, Yap, Kuok, Chan, Lai Yue, Rehm, Fabian B. H., Looi, Fong Yang, Poth, Aaron G., Gilding, Edward K., Kaas, Quentin, Durek, Thomas and Craik, David J. (2020). A bifunctional asparaginyl endopeptidase efficiently catalyzes both cleavage and cyclization of cyclic trypsin inhibitors. Nature Communications, 11 (1) 1575, 1-11. doi: 10.1038/s41467-020-15418-2

A bifunctional asparaginyl endopeptidase efficiently catalyzes both cleavage and cyclization of cyclic trypsin inhibitors

2020

Journal Article

Circular permutation of the native enzyme-mediated cyclization position in cyclotides

Smithies, Bronwyn J., Huang, Yen-Hua, Jackson, Mark A., Yap, Kuok, Gilding, Edward K., Harris, Karen S., Anderson, Marilyn A. and Craik, David J. (2020). Circular permutation of the native enzyme-mediated cyclization position in cyclotides. ACS Chemical Biology, 15 (4) acschembio.9b00996, 962-969. doi: 10.1021/acschembio.9b00996

Circular permutation of the native enzyme-mediated cyclization position in cyclotides

2020

Journal Article

Binding loop substitutions in the cyclic peptide SFTI-1 generate potent and selective chymase inhibitors

Li, Choi Yi, Yap, Kuok, Swedberg, Joakim E., Craik, David J. and de Veer, Simon J. (2020). Binding loop substitutions in the cyclic peptide SFTI-1 generate potent and selective chymase inhibitors. Journal of Medicinal Chemistry, 63 (2) acs.jmedchem.9b01811, 816-826. doi: 10.1021/acs.jmedchem.9b01811

Binding loop substitutions in the cyclic peptide SFTI-1 generate potent and selective chymase inhibitors

2019

Journal Article

Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling

Zhao, Kening, Bleackley, Mark, Chisanga, David, Gangoda, Lahiru, Fonseka, Pamali, Liem, Michael, Kalra, Hina, Al Saffar, Haidar, Keerthikumar, Shivakumar, Ang, Ching-Seng, Adda, Christopher G., Jiang, Lanzhou, Yap, Kuok, Poon, Ivan K., Lock, Peter, Bulone, Vincent, Anderson, Marilyn and Mathivanan, Suresh (2019). Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling. Communications Biology, 2 (1) 305. doi: 10.1038/s42003-019-0538-8

Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling

2019

Journal Article

Site-specific sequential protein labeling catalyzed by a single recombinant ligase

Rehm, Fabian B. H., Harmand, Thibault J., Yap, Kuok, Durek, Thomas, Craik, David J. and Ploegh, Hidde L. (2019). Site-specific sequential protein labeling catalyzed by a single recombinant ligase. Journal of the American Chemical Society, 141 (43) jacs.9b09166, 17388-17393. doi: 10.1021/jacs.9b09166

Site-specific sequential protein labeling catalyzed by a single recombinant ligase

2019

Journal Article

Rapid and scalable plant-based production of a potent plasmin inhibitor peptide

Jackson, Mark A., Yap, Kuok, Poth, Aaron G., Gilding, Edward K., Swedberg, Joakim E., Poon, Simon, Qu, Haiou, Durek, Thomas, Harris, Karen, Anderson, Marilyn A. and Craik, David J. (2019). Rapid and scalable plant-based production of a potent plasmin inhibitor peptide. Frontiers in Plant Science, 10 602, 602. doi: 10.3389/fpls.2019.00602

Rapid and scalable plant-based production of a potent plasmin inhibitor peptide

2019

Journal Article

Papain-like cysteine proteases prepare plant cyclic peptide precursors for cyclization

Rehm, Fabian B. H., Jackson, Mark A., De Geyter, Ewout, Yap, Kuok, Gilding, Edward K., Durek, Thomas and Craik, David J. (2019). Papain-like cysteine proteases prepare plant cyclic peptide precursors for cyclization. Proceedings of the National Academy of Sciences, 116 (16), 7831-7836. doi: 10.1073/pnas.1901807116

Papain-like cysteine proteases prepare plant cyclic peptide precursors for cyclization

2018

Journal Article

Molecular basis for the production of cyclic peptides by plant asparaginyl endopeptidases

Jackson, M. A., Gilding, E. K., Shafee, T., Harris, K. S., Kaas, Q., Poon, S., Yap, K., Jia, H., Guarino, R., Chan, L. Y., Durek, T., Anderson, M. A. and Craik, D. J. (2018). Molecular basis for the production of cyclic peptides by plant asparaginyl endopeptidases. Nature Communications, 9 (1) 2411, 2411. doi: 10.1038/s41467-018-04669-9

Molecular basis for the production of cyclic peptides by plant asparaginyl endopeptidases

2018

Journal Article

Method for hull-less barley transformation and manipulation of grain mixed-linkage beta-glucan

Lim, Wai Li, Collins, Helen M., Singh, Rohan R., Kibble, Natalie A. J., Yap, Kuok, Taylor, Jillian, Fincher, Geoffrey B. and Burton, Rachel A. (2018). Method for hull-less barley transformation and manipulation of grain mixed-linkage beta-glucan. Journal of Integrative Plant Biology, 60 (5), 382-396. doi: 10.1111/jipb.12625

Method for hull-less barley transformation and manipulation of grain mixed-linkage beta-glucan

2018

Journal Article

Functional Characterization of a Glycosyltransferase from the Moss Physcomitrella patens Involved in the Biosynthesis of a Novel Cell Wall Arabinoglucan

Roberts, Alison W., Lahnstein, Jelle, Hsieh, Yves S. Y., Xing, Xiaohui, Yap, Kuok, Chaves, Arielle M., Scavuzzo-Duggan, Tess R., Dimitroff, George, Lonsdale, Andrew, Roberts, Eric M., Bulone, Vincent, Fincher, Geoffrey B., Doblin, Monika Susanne, Bacic, Antony and Burton, Rachel A. (2018). Functional Characterization of a Glycosyltransferase from the Moss Physcomitrella patens Involved in the Biosynthesis of a Novel Cell Wall Arabinoglucan. The Plant Cell, 30 (6), 1293-1308. doi: 10.1105/tpc.18.00082

Functional Characterization of a Glycosyltransferase from the Moss Physcomitrella patens Involved in the Biosynthesis of a Novel Cell Wall Arabinoglucan