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2004 Journal Article A Small Peptide (CEL-1000) Derived from the ß-Chain of the Human Major Histocompatibility Complex Class II Molecule Induces Complete Protection against Malaria in an Antigen-Independent MannerCharoenvit, Yupin, Brice, Gary T., Bacon, David, Majam, Victoria, Williams, Jackie, Abot, Esteban, Ganeshan, Harini, Sedegah, Martha, Doolan, Denise L., Carucci, Daniel J. and Zimmerman, Daniel H. (2004). A Small Peptide (CEL-1000) Derived from the ß-Chain of the Human Major Histocompatibility Complex Class II Molecule Induces Complete Protection against Malaria in an Antigen-Independent Manner. Antimicrobial agents and chemotherapy, 48 (7), 2455-2463. doi: 10.1128/AAC.48.7.2455-2463.2004 |
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2004 Journal Article Induction in Humans of CD8+ and CD4+ T Cell and Antibody Responses by Sequential Immunization with Malaria DNA and Recombinant ProteinWang, Ruobing, Epstein, Judith, Charoenvit, Yupin, Baraceros, Fe Maria, Rahardjo, Nancy, Gay, Tanya, Banania, Jo-Glenna, Chattopadhyay, Rana, de la Vega, Patricia, Richie, Thomas L., Tornieporth, Nadia, Doolan, Denise L., Kester, Kent E., Heppner, D. Gray, Norman, Jon, Carucci, Daniel J., Cohen, Joe D. and Hoffman, Stephen L. (2004). Induction in Humans of CD8+ and CD4+ T Cell and Antibody Responses by Sequential Immunization with Malaria DNA and Recombinant Protein. Journal of immunology, 172 (9), 5561-5569. doi: 10.4049/jimmunol.172.9.5561 |
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2003 Journal Article Utilization of genomic sequence information to develop malaria vaccinesDoolan, D. L., Aguiar, J. C., Weiss, W. R., Sette, A., Felgner, P. L., Regis, D. P., Quinones-Casas, P., Yates, J. R. III, Blair, P. L., Richie, T. L., Hoffman, S. L. and Carucci, D. J. (2003). Utilization of genomic sequence information to develop malaria vaccines. Journal of experimental biology, 206 (21), 3789-3802. doi: 10.1242/jeb.00615 |
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2003 Journal Article Identification of plasmodium falciparum antigens by antigenic analysis of genomic and proteomic dataDoolan, Denise, Southwood, S., Freilich, D. A., Sidney, J., Graber, N. L., Shatney, L., Bebris, L., Florens, L., Dobano, C., Witney, A.A., Apella, E., Hoffman, S. L., Yates, J. R. 3rd, Carucci, D. J. and Sette, A. (2003). Identification of plasmodium falciparum antigens by antigenic analysis of genomic and proteomic data. Proceedings of the National Academy of Sciences of the United States of America, 100 (17), 9952-9957. doi: 10.1073/pnas.1633254100 |
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2002 Journal Article Optimal induction of antigen-specific CD8+ T cell responses requires bystander cell participationBrice, Gary T., Graber, Norma L., Carucci, Daniel J. and Doolan, Denise L. (2002). Optimal induction of antigen-specific CD8+ T cell responses requires bystander cell participation. Journal of leukocyte biology, 72 (6), 1164-1171. doi: 10.1189/jlb.72.6.1164 |
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2002 Journal Article Erratum: Interleukin-12- and gamma interferon-dependent protection against malaria conferred by CpG oligodeoxynucleotide in mice (Infection and Immunity (2001) 69:3 (1643-1649))Gramzinski, Robert A., Doolan, Denise L., Sedegah, Martha, Davis, Heather L., Krieg, Arthur M. and Hoffman, Stephen L. (2002). Erratum: Interleukin-12- and gamma interferon-dependent protection against malaria conferred by CpG oligodeoxynucleotide in mice (Infection and Immunity (2001) 69:3 (1643-1649)). Infection and Immunity, 70 (9). doi: 10.1128/IAI.70.9.5338.2002 |
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2002 Journal Article Persistence of Protective Immunity to Malaria Induced by DNA Priming and Poxvirus Boosting: Characterization of Effector and Memory CD8+-T-Cell PopulationsSedegah, Martha, Brice, Gary T., Rogers, William O., Doolan, Denise L., Charoenvit, Yupin, Jones, Trevor R., Majam, Victoria F., Belmonte, Arnel, Lu, Minh, Belmonte, Maria, Carucci, Daniel J. and Hoffman, Stephen L. (2002). Persistence of Protective Immunity to Malaria Induced by DNA Priming and Poxvirus Boosting: Characterization of Effector and Memory CD8+-T-Cell Populations. Infection and immunity, 70 (7), 3493-3499. doi: 10.1128/IAI.70.7.3493-3499.2002 |
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2002 Journal Article Protection of humans against malaria by immunization with radiation-attenuated Plasmodium falciparum sporozoitesHoffman, Stephen L., Goh, Lucy M. L., Luke, Thomas C., Schneider, Imogene, Le, Thong P., Doolan, Denise L., Sacci, John, De la Vega, Patricia, Dowler, Megan, Paul, Chris, Gordon, Daniel M., Stoute, Jose A., Preston Church, L. W., Sedegah, Martha, Gray Heppner, D., Ripley Ballou, W. and Richie, Thomas L. (2002). Protection of humans against malaria by immunization with radiation-attenuated Plasmodium falciparum sporozoites. Journal of Infectious Diseases, 185 (8), 1155-1164. doi: 10.1086/339409 |
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2002 Journal Article A simple method for delivery and antigen presentation of a malaria protein in human dendritic cells (Application Note)Doolan, Denise L. and Graber, Norma L. (2002). A simple method for delivery and antigen presentation of a malaria protein in human dendritic cells (Application Note). Delivery, 22, 6-7. |
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2002 Journal Article Nucleic acid vaccines against malariaDoolan, Denise L. and Hoffman, Stephen L. (2002). Nucleic acid vaccines against malaria. Chemical Immunology, 80, 308-321. doi: 10.1159/000058851 |
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2001 Journal Article Foreword--MBP thematic issue on genomicsDoolan, D. L., Coppel, R. L. and Waters, A. P. (2001). Foreword--MBP thematic issue on genomics. Molecular and Biochemical Parasitology, 118 (2), 127-8. doi: 10.1016/s0166-6851(01)00389-9 |
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2001 Journal Article Determining liver stage parasite burden by real time quantitative PCR as a method for evaluating pre-erythrocytic malaria vaccine efficacyWitney, Adam A., Doolan, Denise L., Anthony, Robert M., Weiss, Walter R., Hoffman, Stephen L. and Carucci, Daniel J. (2001). Determining liver stage parasite burden by real time quantitative PCR as a method for evaluating pre-erythrocytic malaria vaccine efficacy. Molecular and Biochemical Parasitology, 118 (2), 233-245. doi: 10.1016/S0166-6851(01)00372-3 |
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2001 Journal Article Expression of the chemokine MIG is a sensitive and predictive marker for antigen-specific, genetically restricted IFN-γ production and IFN-γ-secreting cellsBrice, G. T., Graber, N. L., Hoffman, S. L. and Doolan, D. L. (2001). Expression of the chemokine MIG is a sensitive and predictive marker for antigen-specific, genetically restricted IFN-γ production and IFN-γ-secreting cells. Journal of Immunological Methods, 257 (1-2), 55-69. doi: 10.1016/s0022-1759(01)00446-x |
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2001 Journal Article Induction of CD4+ T cell-dependent CD8+ type 1 responses in humans by a malaria DNA vaccineWang, Ruobing, Epstein, Judith, Baraceros, Fe Maria, Gorak, Edward J., Charoenvit, Yupin, Carucci, Daniel J., Hedstrom, Richard C., Rahardjo, Nancy, Gay, Tanya, Hobart, Peter, Stout, Rick, Jones, Trevor R., Richie, Thomas L., Parker, Suezanne E., Doolan, Denise L., Norman, Jon and Hoffman, Stephen L. (2001). Induction of CD4+ T cell-dependent CD8+ type 1 responses in humans by a malaria DNA vaccine. Proceedings of the National Academy of Sciences of the United States of America, 98 (19), 10817-10822. doi: 10.1073/pnas.181123498 |
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2001 Journal Article DNA-based vaccines against malaria: Status and promise of the Multi-Stage Malaria DNA Vaccine OperationDoolan, Denise L and Hoffman, Stephen L (2001). DNA-based vaccines against malaria: Status and promise of the Multi-Stage Malaria DNA Vaccine Operation. International Journal for Parasitology, 31 (8), 753-762. doi: 10.1016/S0020-7519(01)00184-9 |
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2001 Journal Article Interleukin-12- and gamma interferon-dependent protection against malaria conferred by CpG oligodeoxynucleotide in miceGramzinski, R. A., Doolan, D. L., Sedegah, M., Davis, H. L., Krieg, A. M. and Hoffman, S. L. (2001). Interleukin-12- and gamma interferon-dependent protection against malaria conferred by CpG oligodeoxynucleotide in mice. Infection and Immunity, 69 (3), 1643-1649. doi: 10.1128/IAI.69.3.1643-1649.2001 |
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2000 Journal Article Malaria vaccines-targeting infected hepatocytesHoffman, Stephen L. and Doolan, Denise L. (2000). Malaria vaccines-targeting infected hepatocytes. Nature Medicine, 6 (11), 1218-1219. doi: 10.1038/81315 |
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2000 Journal Article HLA degenerate T-cell epitopes from Plasmodium falciparum liver stage-specific antigen 1 (LSA-1) are highly conserved in isolates from geographically distinct areasRavichandran, M., Doolan, D. L., Cox-Singh, J., Hoffman, S. L. and Singh, B. (2000). HLA degenerate T-cell epitopes from Plasmodium falciparum liver stage-specific antigen 1 (LSA-1) are highly conserved in isolates from geographically distinct areas. Parasite Immunology, 22 (9), 469-473. doi: 10.1046/j.1365-3024.2000.00324.x |
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2000 Journal Article The complexity of protective immunity against liver-stage malariaDoolan, Denise L. and Hoffman, Stephen L. (2000). The complexity of protective immunity against liver-stage malaria. Journal of Immunology, 165 (3), 1453-1462. doi: 10.4049/jimmunol.165.3.1453 |
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2000 Journal Article HLA-DR-promiscuous T cell epitopes frown Plasmodium falciparum pre- erythrocytic-stage antigens restricted by multiple HLA class II allelesDoolan, Denise L., Southwood, Scott, Chesnut, Robert, Appella, Ettore, Gomez, Eduardo, Richards, Allen, Higashimoto, Yuichiro I., Maewal, Ajesh, Sidney, John, Gramzinski, Robert A., Mason, Carl, Koech, Davy, Hoffman, Stephen L. and Sette, Alessandro (2000). HLA-DR-promiscuous T cell epitopes frown Plasmodium falciparum pre- erythrocytic-stage antigens restricted by multiple HLA class II alleles. Journal of Immunology, 165 (2), 1123-1137. doi: 10.4049/jimmunol.165.2.1123 |
