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2020

Journal Article

The rise of non-tuberculosis mycobacterial lung disease

Ratnatunga, Champa N., Lutzky, Viviana P., Kupz, Andreas, Doolan, Denise L., Reid, David W., Field, Matthew, Bell, Scott C., Thomson, Rachel M. and Miles, John J. (2020). The rise of non-tuberculosis mycobacterial lung disease. Frontiers in Immunology, 11 303, 303. doi: 10.3389/fimmu.2020.00303

The rise of non-tuberculosis mycobacterial lung disease

2020

Journal Article

Deciphering host immunity to malaria using systems immunology

Loiseau, Claire, Cooper, Martha M. and Doolan, Denise L. (2020). Deciphering host immunity to malaria using systems immunology. Immunological Reviews, 293 (1), 115-143. doi: 10.1111/imr.12814

Deciphering host immunity to malaria using systems immunology

2019

Journal Article

Protective immunity against severe malaria in children is associated with a limited repertoire of antibodies to conserved PfEMP1 variants

Tessema, Sofonias K., Nakajima, Rie, Jasinskas, Algis, Monk, Stephanie L., Lekieffre, Lea, Lin, Enmoore, Kiniboro, Benson, Proietti, Carla, Siba, Peter, Felgner, Philip L., Doolan, Denise L., Mueller, Ivo and Barry, Alyssa E. (2019). Protective immunity against severe malaria in children is associated with a limited repertoire of antibodies to conserved PfEMP1 variants. Cell Host & Microbe, 26 (5), 579-590+. doi: 10.1016/j.chom.2019.10.012

Protective immunity against severe malaria in children is associated with a limited repertoire of antibodies to conserved PfEMP1 variants

2019

Journal Article

Multilaboratory assessment of Epstein-Barr virus serologic assays: the case for standardization

Liu, Zhiwei, Yu, Kelly J., Coghill, Anna E., Brenner, Nicole, Cao, Su-Mei, Chen, Chien-Jen, Chen, Yufeng, Doolan, Denise L., Hsu, Wan-Lun, Labo, Nazzarena, Middeldorp, Jaap M., Miley, Wendell, Simon, Julia, Wang, Cheng-Ping, Waterboer, Tim, Whitby, Denise, Xie, Shang-Hang, Ye, Weimin and Hildesheim, Allan (2019). Multilaboratory assessment of Epstein-Barr virus serologic assays: the case for standardization. Journal of Clinical Microbiology, 57 (11) e01107-19, 1-8. doi: 10.1128/JCM.01107-19

Multilaboratory assessment of Epstein-Barr virus serologic assays: the case for standardization

2019

Journal Article

Casting a wide net around immunity to malaria catches p53

Cooper, Martha M., Loiseau, Claire and Doolan, Denise L. (2019). Casting a wide net around immunity to malaria catches p53. Immunity, 51 (4), 603-605. doi: 10.1016/j.immuni.2019.09.011

Casting a wide net around immunity to malaria catches p53

2019

Journal Article

IgM in human immunity to Plasmodium falciparum malaria

Boyle, M. J., Chan, J. A., Handayuni, I., Reiling, L., Feng, G., Hilton, A., Kurtovic, L., Oyong, D., Piera, K. A., Barber, B. E., William, T., Eisen, D. P., Minigo, G., Langer, C., Drew, D. R., de Labastida Rivera, F., Amante, F. H., Williams, T. N., Kinyanjui, S., Marsh, K., Doolan, D. L., Engwerda, C., Fowkes, F. J.I., Grigg, M. J., Mueller, I., McCarthy, J. S., Anstey, N. M. and Beeson, J. G. (2019). IgM in human immunity to Plasmodium falciparum malaria. Science Advances, 5 (9) eaax4489, eaax4489. doi: 10.1126/sciadv.aax4489

IgM in human immunity to Plasmodium falciparum malaria

2019

Journal Article

2018 ISV Congress: advances in the 100 years since the world’s deadliest pandemic

Doolan, Denise L. and Ross, Ted M. (2019). 2018 ISV Congress: advances in the 100 years since the world’s deadliest pandemic. Human Vaccines & Immunotherapeutics, 15 (9), 2006-2008. doi: 10.1080/21645515.2019.1660544

2018 ISV Congress: advances in the 100 years since the world’s deadliest pandemic

2019

Journal Article

A balanced proinflammatory and regulatory cytokine signature in young African children is associated with lower risk of clinical malaria

Dobaño, Carlota, Nhabomba, Augusto J, Manaca, Maria N, Berthoud, Tamara, Aguilar, Ruth, Quintó, Llorenç, Barbosa, Arnoldo, Rodríguez, Mauricio H, Jiménez, Alfons, Groves, Penny L, Santano, Rebeca, Bassat, Quique, Aponte, John J, Guinovart, Caterina, Doolan, Denise L and Alonso, Pedro L (2019). A balanced proinflammatory and regulatory cytokine signature in young African children is associated with lower risk of clinical malaria. Clinical Infectious Diseases, 69 (5) ciy934, 820-828. doi: 10.1093/cid/ciy934

A balanced proinflammatory and regulatory cytokine signature in young African children is associated with lower risk of clinical malaria

2019

Journal Article

Chimeric Murine Polyomavirus Virus-Like Particles Induce Plasmodium Antigen-Specific CD8(+) T Cell and Antibody Responses

Pattinson, David J., Apte, Simon H., Wibowo, Nani, Chuan, Yap P., Rivera-Hernandez, Tania, Groves, Penny L., Lua, Linda H., Middelberg, Anton P. J. and Doolan, Denise L. (2019). Chimeric Murine Polyomavirus Virus-Like Particles Induce Plasmodium Antigen-Specific CD8(+) T Cell and Antibody Responses. Frontiers in Cellular and Infection Microbiology, 9 (JUN) 215, 215. doi: 10.3389/fcimb.2019.00215

Chimeric Murine Polyomavirus Virus-Like Particles Induce Plasmodium Antigen-Specific CD8(+) T Cell and Antibody Responses

2019

Journal Article

Human challenge models: tools to accelerate the development of malaria vaccines

Cooper, Martha M., Loiseau, Claire, McCarthy, James S. and Doolan, Denise L. (2019). Human challenge models: tools to accelerate the development of malaria vaccines. Expert Review of Vaccines, 18 (3), 241-251. doi: 10.1080/14760584.2019.1580577

Human challenge models: tools to accelerate the development of malaria vaccines

2018

Journal Article

Identification of Cytauxzoon felis antigens via protein microarray and assessment of expression library immunization against cytauxzoonosis

Schreeg, Megan E, Marr, Henry S, Tarigo, Jaime L, Sherrill, Meredith K, Outi, Hilton K, Scholl, Elizabeth H, Bird, David M, Vigil, Adam, Hung, Chris, Nakajima, Rie, Liang, Li, Trieu, Angela, Doolan, Denise L, Thomas, Jennifer E, Levy, Michael G, Reichard, Mason V, Felgner, Philip L, Cohn, Leah A and Birkenheuer, Adam J (2018). Identification of Cytauxzoon felis antigens via protein microarray and assessment of expression library immunization against cytauxzoonosis. Clinical Proteomics, 15 (1) 44, 1-17. doi: 10.1186/s12014-018-9218-9

Identification of Cytauxzoon felis antigens via protein microarray and assessment of expression library immunization against cytauxzoonosis

2018

Journal Article

Defined Small Molecules Produced by Himalayan Medicinal Plants Display Immunomodulatory Properties

Wangchuk, Phurpa, Apte, Simon H., Smout, Michael J., Groves, Penny L., Loukas, Alex and Doolan, Denise L. (2018). Defined Small Molecules Produced by Himalayan Medicinal Plants Display Immunomodulatory Properties. International journal of molecular sciences, 19 (11) 3490, 3490. doi: 10.3390/ijms19113490

Defined Small Molecules Produced by Himalayan Medicinal Plants Display Immunomodulatory Properties

2018

Journal Article

ISV Congress back to Europe

Doolan, Denise L. and Lu, Shan (2018). ISV Congress back to Europe. Human Vaccines and Immunotherapeutics, 14 (9), 2101-2104. doi: 10.1080/21645515.2018.1518065

ISV Congress back to Europe

2018

Journal Article

Patterns of interindividual variability in the antibody repertoire targeting proteins across the Epstein-Barr virus proteome

Liu, Zhiwei, Coghill, Anna E., Pfeiffer, Ruth M., Proietti, Carla, Hsu, Wan-Lun, Chien, Yin-Chu, Lekieffre, Lea, Krause, Lutz, Yu, Kelly J., Lou, Pei-Jen, Wang, Cheng-Ping, Mulvenna, Jason, Middeldorp, Jaap M., Bethony, Jeff, Chen, Chien-Jen, Doolan, Denise L. and Hildesheim, Allan (2018). Patterns of interindividual variability in the antibody repertoire targeting proteins across the Epstein-Barr virus proteome. The Journal of Infectious Diseases, 217 (12), 1923-1931. doi: 10.1093/infdis/jiy122

Patterns of interindividual variability in the antibody repertoire targeting proteins across the Epstein-Barr virus proteome

2018

Journal Article

Anomalies in T cell function are associated with individuals at risk of Mycobacterium abscessus complex infection

Lutzky, Viviana P., Ratnatunga, Champa N., Smith, Daniel J., Kupz, Andreas, Doolan, Denise L., Reid, David W., Thomson, Rachel M., Bell, Scott C. and Miles, John J. (2018). Anomalies in T cell function are associated with individuals at risk of Mycobacterium abscessus complex infection. Frontiers in Immunology, 9 (June) 1319, 1319. doi: 10.3389/fimmu.2018.01319

Anomalies in T cell function are associated with individuals at risk of Mycobacterium abscessus complex infection

2018

Journal Article

High production of pro-inflammatory cytokines by maternal blood mononuclear cells is associated with reduced maternal malaria but increased cord blood infection

Dobaño, Carlota, Berthoud, Tamara, Manaca, Maria Nelia, Nhabomba, Augusto, Guinovart, Caterina, Aguilar, Ruth, Barbosa, Arnoldo, Groves, Penny, Rodríguez, Mauricio H, Jimenez, Alfons, Quimice, Lazaro M, Aponte, John J, Ordi, Jaume, Doolan, Denise L, Mayor, Alfredo and Alonso, Pedro L (2018). High production of pro-inflammatory cytokines by maternal blood mononuclear cells is associated with reduced maternal malaria but increased cord blood infection. Malaria Journal, 17 (1) 177, 1-13. doi: 10.1186/s12936-018-2317-2

High production of pro-inflammatory cytokines by maternal blood mononuclear cells is associated with reduced maternal malaria but increased cord blood infection

2018

Journal Article

The influence of physicochemical properties of lipopeptide adjuvants on immune response: a rationale for engineering a potent vaccine

Eskandari, Sharareh, Pattinson, David, Stephenson, Rachel J., Groves, Penny L., Apte, Simon H., Sedaghat, Bita, Chandurudu, Saranya, Doolan, Denise L. and Toth, Istvan (2018). The influence of physicochemical properties of lipopeptide adjuvants on immune response: a rationale for engineering a potent vaccine. Chemistry: A European Journal, 24 (39), 9892-9902. doi: 10.1002/chem.201801378

The influence of physicochemical properties of lipopeptide adjuvants on immune response: a rationale for engineering a potent vaccine

2018

Journal Article

Identification of a Novel, EBV-based antibody risk stratification signature for early detection of nasopharyngeal carcinoma in Taiwan

Coghill, Anna E., Pfeiffer, Ruth M., Proietti, Carla, Hsu, Wan-Lun, Chien, Yin-Chu, Lekieffre, Lea, Krause, Lutz, Teng, Andy, Pablo, Jocelyn, Yu, Kelly J., Lou, Pei-Jen, Wang, Cheng-Ping, Liu, Zhiwei, Chen, Chien-Jen, Middeldorp, Jaap, Mulvenna, Jason, Bethony, Jeff, Hildesheim, Allan and Doolan, Denise L. (2018). Identification of a Novel, EBV-based antibody risk stratification signature for early detection of nasopharyngeal carcinoma in Taiwan. Clinical Cancer Research, 24 (6), 1305-1314. doi: 10.1158/1078-0432.CCR-17-1929

Identification of a Novel, EBV-based antibody risk stratification signature for early detection of nasopharyngeal carcinoma in Taiwan

2017

Journal Article

Profiling the targets of protective CD8+ T cell responses to infection

Bruder, Joseph T., Chen, Ping, Ekberg, Greg, Smith, Emily C., Lazarski, Christopher A., Myers, Bennett A., Bolton, Jessica, Sedegah, Martha, Villasante, Eileen, Richie, Thomas L., King, C Richter, Aguiar, Joao C., Doolan, Denise L. and Brough, Douglas E. (2017). Profiling the targets of protective CD8+ T cell responses to infection. Molecular Therapy - Methods & Clinical Development, 7, 20-31. doi: 10.1016/j.omtm.2017.08.003

Profiling the targets of protective CD8+ T cell responses to infection

2017

Journal Article

Novel Plasmodium antigens identified via genome-based antibody screen induce protection associated with polyfunctional T cell responses

Schussek, Sophie, Trieu, Angela, Apte, Simon H., Sidney, John, Sette, Alessandro and Doolan, Denise L. (2017). Novel Plasmodium antigens identified via genome-based antibody screen induce protection associated with polyfunctional T cell responses. Scientific reports, 7 (1) 15053, 1-18. doi: 10.1038/s41598-017-15354-0

Novel Plasmodium antigens identified via genome-based antibody screen induce protection associated with polyfunctional T cell responses