|
2022 Journal Article Nucleocapsid specific diagnostics for the detection of divergent SARS-CoV-2 variantsIsaacs, Ariel, Amarilla, Alberto A., Aguado, Julio, Modhiran, Naphak, Albornoz, Eduardo A., Baradar, Alireza A., McMillan, Christopher L. D., Choo, Jovin J. Y., Idris, Adi, Supramaniam, Aroon, McMillan, Nigel A. J., Muller, David A., Young, Paul R., Woodruff, Trent M., Wolvetang, Ernst J., Chappell, Keith J. and Watterson, Daniel (2022). Nucleocapsid specific diagnostics for the detection of divergent SARS-CoV-2 variants. Frontiers in Immunology, 13 926262, 926262. doi: 10.3389/fimmu.2022.926262 |
|
2022 Journal Article Thrombin differentially modulates the acute inflammatory response to Escherichia coli and Staphylococcus aureus in human whole bloodJohnson, Christina, Quach, Huy Quang, Lau, Corinna, Ekholt, Karin, Espevik, Terje, Woodruff, Trent M., Pischke, Søren Erik, Mollnes, Tom Eirik and Nilsson, Per H. (2022). Thrombin differentially modulates the acute inflammatory response to Escherichia coli and Staphylococcus aureus in human whole blood. The Journal of Immunology, 208 (12), 2771-2778. doi: 10.4049/jimmunol.2101033 |
|
2022 Journal Article Bothrops jararaca snake venom inflammation induced in human whole blood: role of the complement systemLeonel, Thyago Bispo, Gabrili, Joel José Megale, Squaiella-Baptistão, Carla Cristina, Woodruff, Trent M., Lambris, John D. and Tambourgi, Denise V. (2022). Bothrops jararaca snake venom inflammation induced in human whole blood: role of the complement system. Frontiers in Immunology, 13 885223, 1-16. doi: 10.3389/fimmu.2022.885223 |
|
2022 Journal Article Complement drives circuit modulation in the adult brainParker, Sandra E., Bellingham, Mark C. and Woodruff, Trent M. (2022). Complement drives circuit modulation in the adult brain. Progress in Neurobiology, 214 102282, 102282. doi: 10.1016/j.pneurobio.2022.102282 |
|
2022 Journal Article Complement C5a induces the formation of neutrophil extracellular traps by myeloid-derived suppressor cells to promote metastasisOrtiz-Espinosa, Sergio, Morales, Xabier, Senent, Yaiza, Alignani, Diego, Tavira, Beatriz, Macaya, Irati, Ruiz, Borja, Moreno, Haritz, Remírez, Ana, Sainz, Cristina, Rodriguez-Pena, Alejandro, Oyarbide, Alvaro, Ariz, Mikel, Andueza, Maria P., Valencia, Karmele, Teijeira, Alvaro, Hoehlig, Kai, Vater, Axel, Rolfe, Barbara, Woodruff, Trent M., Lopez-Picazo, Jose Maria, Vicent, Silvestre, Kochan, Grazyna, Escors, David, Gil-Bazo, Ignacio, Perez-Gracia, Jose Luis, Montuenga, Luis M., Lambris, John D., Ortiz de Solorzano, Carlos ... Pio, Ruben (2022). Complement C5a induces the formation of neutrophil extracellular traps by myeloid-derived suppressor cells to promote metastasis. Cancer Letters, 529, 70-84. doi: 10.1016/j.canlet.2021.12.027 |
|
2022 Journal Article Reduced Growth, Altered Gut Microbiome and Metabolite Profile, and Increased Chronic Kidney Disease Risk in Young Pigs Consuming a Diet Containing Highly Resistant ProteinMurray, Margaret, Coughlan, Melinda T., Gibbon, Anne, Kumar, Vinod, Marques, Francine Z., Selby-Pham, Sophie, Snelson, Matthew, Tsyganov, Kirill, Williamson, Gary, Woodruff, Trent M., Wu, Tong and Bennett, Louise E. (2022). Reduced Growth, Altered Gut Microbiome and Metabolite Profile, and Increased Chronic Kidney Disease Risk in Young Pigs Consuming a Diet Containing Highly Resistant Protein. Frontiers in Nutrition, 9 816749, 816749. doi: 10.3389/fnut.2022.816749 |
|
2021 Journal Article In vivo pharmacodynamic method to assess complement C5a receptor antagonist efficacyCui, Cedric S., Kumar, Vinod, Gorman, Declan M., Clark, Richard J., Lee, John D. and Woodruff, Trent M. (2021). In vivo pharmacodynamic method to assess complement C5a receptor antagonist efficacy. ACS Pharmacology and Translational Science, 5 (1) acsptsci.1c00227, 41-51. doi: 10.1021/acsptsci.1c00227 |
|
2021 Journal Article Unexpected off-target activities for recombinant C5a in human macrophagesLi, Xaria X., Gorman, Declan M., Lee, John D., Clark, Richard J. and Woodruff, Trent M. (2021). Unexpected off-target activities for recombinant C5a in human macrophages. Journal of Immunology, 208 (1), 133-142. doi: 10.4049/jimmunol.2100444 |
|
2021 Journal Article Sustained-release ketamine-loaded lipid-particulate system: in vivo assessment in miceXu, Weizhi, Maqbool, Faheem, Kumar, Vinod, Falconer, James R., Cui, Cedric S., Woodruff, Trent M., Borges, Karin, Whittaker, Andrew K., Smith, Maree T. and Han, Felicity Y. (2021). Sustained-release ketamine-loaded lipid-particulate system: in vivo assessment in mice. Drug Delivery and Translational Research, 12 (10), 2518-2526. doi: 10.1007/s13346-021-01093-3 |
|
2021 Journal Article Development of synthetic human and mouse C5a: application to binding and functional assays in vitro and in vivoGorman, Declan M., Li, Xaria X., Payne, Colton D., Cui, Cedric S., Lee, John D., Rosengren, K. Johan, Woodruff, Trent M. and Clark, Richard J. (2021). Development of synthetic human and mouse C5a: application to binding and functional assays in vitro and in vivo. ACS Pharmacology and Translational Science, 4 (6) acsptsci.1c00199, 1808-1817. doi: 10.1021/acsptsci.1c00199 |
|
2021 Journal Article Development of Potent and Selective Agonists for Complement C5a Receptor 1 with In Vivo ActivityGorman, Declan M., Li, Xaria X., Lee, John D., Fung, Jenny N., Cui, Cedric S., Lee, Han Siean, Rolfe, Barbara E., Woodruff, Trent M. and Clark, Richard J. (2021). Development of Potent and Selective Agonists for Complement C5a Receptor 1 with In Vivo Activity. Journal of Medicinal Chemistry, 64 (22) acs.jmedchem.1c01174, 16598-16608. doi: 10.1021/acs.jmedchem.1c01174 |
|
2021 Journal Article Air bubbles activate complement and trigger hemostasis and C3-dependent cytokine release ex vivo in human whole bloodStorm, Benjamin S., Christiansen, Dorte, Fure, Hilde, Ludviksen, Judith K., Lau, Corinna, Lambris, John D., Woodruff, Trent M., Brekke, Ole-Lars, Braaten, Tonje, Nielsen, Erik W. and Mollnes, Tom Eirik (2021). Air bubbles activate complement and trigger hemostasis and C3-dependent cytokine release ex vivo in human whole blood. The Journal of Immunology, 207 (11), ji2100308-2840. doi: 10.4049/jimmunol.2100308 |
|
2021 Journal Article Intrinsic bias at non-canonical, β-arrestin-coupled seven transmembrane receptorsPandey, Shubhi, Kumari, Punita, Baidya, Mithu, Kise, Ryoji, Cao, Yubo, Dwivedi-Agnihotri, Hemlata, Banerjee, Ramanuj, Li, Xaria X., Cui, Cedric S., Lee, John D., Kawakami, Kouki, Maharana, Jagannath, Ranjan, Ashutosh, Chaturvedi, Madhu, Jhingan, Gagan Deep, Laporte, Stéphane A., Woodruff, Trent M., Inoue, Asuka and Shukla, Arun K. (2021). Intrinsic bias at non-canonical, β-arrestin-coupled seven transmembrane receptors. Molecular Cell, 81 (22), 4605-4621.e11. doi: 10.1016/j.molcel.2021.09.007 |
|
2021 Journal Article Anaphylatoxin receptor promiscuity for commonly used complement C5a peptide agonistsLi, Xaria X., Clark, Richard J. and Woodruff, Trent M. (2021). Anaphylatoxin receptor promiscuity for commonly used complement C5a peptide agonists. International Immunopharmacology, 100 108074, 108074. doi: 10.1016/j.intimp.2021.108074 |
|
2021 Journal Article The emerging role of complement in neuromuscular disordersLee, John D. and Woodruff, Trent M. (2021). The emerging role of complement in neuromuscular disorders. Seminars in Immunopathology, 43 (6), 817-828. doi: 10.1007/s00281-021-00895-4 |
|
2021 Journal Article Optimisation of a microfluidic method for the delivery of a small peptideHan, Felicity Y., Xu, Weizhi, Kumar, Vinod, Cui, Cedric S., Li, Xaria, Jiang, Xingyu, Woodruff, Trent M., Whittaker, Andrew K. and Smith, Maree T. (2021). Optimisation of a microfluidic method for the delivery of a small peptide. Pharmaceutics, 13 (9) 1505, 1505. doi: 10.3390/pharmaceutics13091505 |
|
2021 Journal Article The concise guide to pharmacology 2021/22: G protein‐coupled receptorsAlexander, Stephen PH, Christopoulos, Arthur, Davenport, Anthony P, Kelly, Eamonn, Mathie, Alistair, Peters, John A, Veale, Emma L, Armstrong, Jane F, Faccenda, Elena, Harding, Simon D, Pawson, Adam J, Southan, Christopher, Davies, Jamie A, Abbracchio, Maria Pia, Alexander, Wayne, Al‐hosaini, Khaled, Bäck, Magnus, Barnes, Nicholas M., Bathgate, Ross, Beaulieu, Jean‐Martin, Bernstein, Kenneth E., Bettler, Bernhard, Birdsall, Nigel J.M., Blaho, Victoria, Boulay, Francois, Bousquet, Corinne, Bräuner‐Osborne, Hans, Burnstock, Geoffrey, Caló, Girolamo ... Ye, Richard D. (2021). The concise guide to pharmacology 2021/22: G protein‐coupled receptors. British Journal of Pharmacology, 178 (S1), S27-S156. doi: 10.1111/bph.15538 |
|
2021 Journal Article Complement peptide receptors in GtoPdb v.2021.3Cianciulli, Antonia, Coulthard, Liam, Hawksworth, Owen, Lee, John D., Li, Xaria X., Mitolo, Vincenzo, Monk, Peter, Panaro, Maria A. and Woodruff, Trent M. (2021). Complement peptide receptors in GtoPdb v.2021.3. IUPHAR/BPS Guide to Pharmacology CITE, 2021 (3), 1-13. doi: 10.2218/gtopdb/f5/2021.3 |
|
2021 Journal Article The complement cascade in the regulation of neuroinflammation, nociceptive sensitization, and painWarwick, Charles A., Keyes, Alex L., Woodruff, Trent M. and Usachev, Yuriy M. (2021). The complement cascade in the regulation of neuroinflammation, nociceptive sensitization, and pain. Journal of Biological Chemistry, 297 (3) 101085, 101085. doi: 10.1016/J.JBC.2021.101085 |
|
2021 Journal Article Monocyte CD14 and HLA-DR expression increases with disease duration and severity in amyotrophic lateral sclerosisMcGill, R.B., Steyn, F.J., Ngo, S.T., Thorpe, K.A., Heggie, S., Henderson, R.D., Mccombe, P.A. and Woodruff, T.M. (2021). Monocyte CD14 and HLA-DR expression increases with disease duration and severity in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 23 (5-6), 1-8. doi: 10.1080/21678421.2021.1964531 |
