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2024

Journal Article

Behavioural ‘nudging’ interventions to reduce low-value care for low back pain in the emergency department (NUDG-ED): protocol for a 2×2 factorial, before-after, cluster randomised trial

Altinger, Gemma, Sharma, Sweekriti, Maher, Chris G, Cullen, Louise, McCaffery, Kirsten, Linder, Jeffrey A, Buchbinder, Rachelle, Harris, Ian A, Coiera, Enrico, Li, Qiang, Howard, Kirsten, Coggins, Andrew, Middleton, Paul M, Gunja, Naren, Ferguson, Ian, Chan, Trevor, Tambree, Karen, Varshney, Ajay and Traeger, Adrian C (2024). Behavioural ‘nudging’ interventions to reduce low-value care for low back pain in the emergency department (NUDG-ED): protocol for a 2×2 factorial, before-after, cluster randomised trial. BMJ Open, 14 (3) e079870, 1-12. doi: 10.1136/bmjopen-2023-079870

Behavioural ‘nudging’ interventions to reduce low-value care for low back pain in the emergency department (NUDG-ED): protocol for a 2×2 factorial, before-after, cluster randomised trial

2024

Journal Article

External validation of a rapid algorithm using high-sensitivity troponin assay results for evaluating patients with suspected acute myocardial infarction

Cullen, Louise, Greenslade, Jaimi H., Stephensen, Laura, Ranasinghe, Isuru, Gaikwad, Niranjan, Khorramshahi Bayat, Maryam, Mahmoodi, Ehsan, Than, Martin, Apple, Fred, Parsonage, William and SAMIE study group 2022 (2024). External validation of a rapid algorithm using high-sensitivity troponin assay results for evaluating patients with suspected acute myocardial infarction. Emergency Medicine Journal, 41 (5), 313-319. doi: 10.1136/emermed-2023-213539

External validation of a rapid algorithm using high-sensitivity troponin assay results for evaluating patients with suspected acute myocardial infarction

2024

Journal Article

Biomarkers for diagnosis and prognostication of acute aortic syndromes

Morello, Fulvio, Nazerian, Peiman, Lupia, Enrico, Castelli, Matteo, Mills, Nicholas L, Mueller, Christian, Giannitsis, Evangelos, Daniels, Lori, Huber, Kurt, Mair, Johannes, Cullen, Louise, Hammarsten, Ola, Möckel, Martin, Krychtiuk, Konstantin, Thygesen, Kristian, Thielmann, Matthias, Jaffe, Allan S. and the Study Group on Biomarkers of the ESC Association for Acute Cardiovascular Care (2024). Biomarkers for diagnosis and prognostication of acute aortic syndromes. European Heart Journal: Acute Cardiovascular Care, 13 (2), 254-256. doi: 10.1093/ehjacc/zuae011

Biomarkers for diagnosis and prognostication of acute aortic syndromes

2023

Journal Article

Aiming toWards Evidence baSed inTerpretation of Cardiac biOmarkers in patients pResenting with chest pain using Point of Care Testing (WESTCOR-POC): study design

Thulin, Ingrid Viola Lavesson, Jordalen, Silje Marie Farestveit, Lekven, Ole Christian, Krishnapillai, Jeyaseelan, Steiro, Ole Thomas, Collinson, Paul, Apple, Fred, Cullen, Louise, Norekval, Tone M., Wisloff, Torbjorn, Vikenes, Kjell, Omland, Torbjorn, Bjorneklett, Rune O. and Aakre, Kristin Moberg (2023). Aiming toWards Evidence baSed inTerpretation of Cardiac biOmarkers in patients pResenting with chest pain using Point of Care Testing (WESTCOR-POC): study design. Scandinavian Cardiovascular Journal, 57 (1) 2272585, 1-7. doi: 10.1080/14017431.2023.2272585

Aiming toWards Evidence baSed inTerpretation of Cardiac biOmarkers in patients pResenting with chest pain using Point of Care Testing (WESTCOR-POC): study design

2023

Journal Article

Impacts of high sensitivity troponin T reporting on care and outcomes in clinical practice: interactions between low troponin concentrations and participant sex within two randomized clinical trials

Lambrakis, Kristina, Khan, Ehsan, van den Merkhof, Anke, Papendick, Cynthia, Chuang, Anthony, Zhai, Yuze, Eng-Frost, Joanne, Rocheleau, Simon, Lehman, Sam J., Blyth, Andrew, Briffa, Tom, Quinn, Stephen, French, John K., Cullen, Louise and Chew, Derek P. (2023). Impacts of high sensitivity troponin T reporting on care and outcomes in clinical practice: interactions between low troponin concentrations and participant sex within two randomized clinical trials. International Journal of Cardiology, 393 131396, 1-8. doi: 10.1016/j.ijcard.2023.131396

Impacts of high sensitivity troponin T reporting on care and outcomes in clinical practice: interactions between low troponin concentrations and participant sex within two randomized clinical trials

2023

Journal Article

Suspected myocardial infarction in the emergency department: An evaluation of clinical thresholds for the Beckman Coulter Access hsTnI high-sensitivity cardiac troponin I assay

Meek, Robert, Cullen, Louise, Lu, Zhong, Nasis, Arthur, Kuhn, Lisa and Sorace, Laurence (2023). Suspected myocardial infarction in the emergency department: An evaluation of clinical thresholds for the Beckman Coulter Access hsTnI high-sensitivity cardiac troponin I assay. EMA - Emergency Medicine Australasia, 35 (6), 1005-1012. doi: 10.1111/1742-6723.14282

Suspected myocardial infarction in the emergency department: An evaluation of clinical thresholds for the Beckman Coulter Access hsTnI high-sensitivity cardiac troponin I assay

2023

Journal Article

Cardiac troponin T and I: back to basics

Mingels, Alma M., Mills, Nicholas L., Mueller, Christian, Jaffe, Allan, Giannitsis, Evangelos, Daniels, Lori, Huber, Kurt, Mair, Johannes, Cullen, Louise, Hammarsten, Ola, Möckel, Martin, Krychtiuk, Konstantin, Thygesen, Kristian, Thielmann, Matthias and Study Group on Biomarkers of the ESC Association for Acute CardioVascular Care (2023). Cardiac troponin T and I: back to basics. European Heart Journal: Acute Cardiovascular Care, 12 (9), 631-632. doi: 10.1093/ehjacc/zuad084

Cardiac troponin T and I: back to basics

2023

Journal Article

Improving difficult peripheral intravenous access requires thought, training and technology (DART3): a stepped-wedge, cluster randomised controlled trial protocol

Schults, Jessica A., Marsh, Nicole, Ullman, Amanda J., Kleidon, Tricia M., Ware, Robert S., Byrnes, Joshua, Young, Emily, Hall, Lisa, Keijzers, Gerben, Cullen, Louise, Calleja, Pauline, McTaggart, Steven, Peters, Nathan, Watkins, Stuart, Corley, Amanda, Brown, Christine, Lin, Zhen, Williamson, Frances, Burgess, Luke, Macfarlane, Fiona, Cooke, Marie, Battley, Callan and Rickard, Claire M. (2023). Improving difficult peripheral intravenous access requires thought, training and technology (DART3): a stepped-wedge, cluster randomised controlled trial protocol. BMC Health Services Research, 23 (1) 587, 1-12. doi: 10.1186/s12913-023-09499-0

Improving difficult peripheral intravenous access requires thought, training and technology (DART3): a stepped-wedge, cluster randomised controlled trial protocol

2023

Journal Article

Healthcare cost burden of acute chest pain presentations

Dawson, Luke, Nehme, Emily, Nehme, Ziad, Zomer, Ella, Bloom, Jason, Cox, Shelley, Anderson, David, Stephenson, Michael, Lefkovits, Jeffrey, Taylor, Andrew, Kaye, David, Cullen, Louise, Smith, Karen and Stub, Dion (2023). Healthcare cost burden of acute chest pain presentations. Emergency Medicine Journal, 40 (6) emermed-2022-212674, 1-7. doi: 10.1136/emermed-2022-212674

Healthcare cost burden of acute chest pain presentations

2023

Journal Article

High-sensitivity cardiac troponin in stable atherosclerotic vascular disease

Morrow, David A., Mills, Nicholas L., Mueller, Christian, Jaffe, Allan, Giannitsis, Evangelos, Daniels, Lori, Huber, Kurt, Mair, Johannes, Cullen, Louise, Hammarsten, Ola, Möckel, Martin, Krychtiuk, Konstantin, Thygesen, Kristian and Thielmann, Matthias (2023). High-sensitivity cardiac troponin in stable atherosclerotic vascular disease. European Heart Journal: Acute Cardiovascular Care, 12 (6), 396-398. doi: 10.1093/ehjacc/zuad054

High-sensitivity cardiac troponin in stable atherosclerotic vascular disease

2023

Journal Article

Clinical characteristics of Aboriginal and Torres Strait Islander emergency department patients with suspected acute coronary syndrome

Stephensen, Laura, Greenslade, Jaimi, Starmer, Katrina, Starmer, Greg, Stone, Richard, Bonnin, Robert, Brazzale, Anthony, Drahm‐Butler, Tileah, Campbell, Virginia, Davis, Tania, Mowatt, Elizabeth, Brown, Nathan, Proctor, Karlie, Ashover, Sarah, Milburn, Tanya, McCormack, Louise, Graves, Nicholas, Gatton, Michelle, Mahoney, Ray, Parsonage, William and Cullen, Louise (2023). Clinical characteristics of Aboriginal and Torres Strait Islander emergency department patients with suspected acute coronary syndrome. Emergency Medicine Australasia, 35 (3), 442-449. doi: 10.1111/1742-6723.14138

Clinical characteristics of Aboriginal and Torres Strait Islander emergency department patients with suspected acute coronary syndrome

2023

Journal Article

Machine learning for diagnosis of myocardial infarction using cardiac troponin concentrations

Doudesis, Dimitrios, Lee, Kuan Ken, Boeddinghaus, Jasper, Bularga, Anda, Ferry, Amy V., Tuck, Chris, Lowry, Matthew T. H., Lopez-Ayala, Pedro, Nestelberger, Thomas, Koechlin, Luca, Bernabeu, Miguel O., Neubeck, Lis, Anand, Atul, Schulz, Karen, Apple, Fred S., Parsonage, William, Greenslade, Jaimi H., Cullen, Louise, Pickering, John W., Than, Martin P., Gray, Alasdair, Mueller, Christian, Mills, Nicholas L., Richards, A. Mark, Pemberton, Chris, Troughton, Richard W., Aldous, Sally J., Brown, Anthony F. T., Dalton, Emily ... CoDE-ACS Investigators (2023). Machine learning for diagnosis of myocardial infarction using cardiac troponin concentrations. Nature Medicine, 29 (5), 1201-1210. doi: 10.1038/s41591-023-02325-4

Machine learning for diagnosis of myocardial infarction using cardiac troponin concentrations

2023

Journal Article

Personalized diagnosis in suspected myocardial infarction

Neumann, Johannes Tobias, Twerenbold, Raphael, Ojeda, Francisco, Aldous, Sally J., Allen, Brandon R., Apple, Fred S., Babel, Hugo, Christenson, Robert H., Cullen, Louise, Di Carluccio, Eleonora, Doudesis, Dimitrios, Ekelund, Ulf, Giannitsis, Evangelos, Greenslade, Jaimi, Inoue, Kenji, Jernberg, Tomas, Kavsak, Peter, Keller, Till, Lee, Kuan Ken, Lindahl, Bertil, Lorenz, Thiess, Mahler, Simon A., Mills, Nicholas L., Mokhtari, Arash, Parsonage, William, Pickering, John W., Pemberton, Christopher J., Reich, Christoph, Richards, A. Mark ... Zournazi, Anna (2023). Personalized diagnosis in suspected myocardial infarction. Clinical Research in Cardiology, 112 (9), 1288-1301. doi: 10.1007/s00392-023-02206-3

Personalized diagnosis in suspected myocardial infarction

2023

Journal Article

Rapid rule-out of myocardial infarction using a single high-sensitivity cardiac troponin I measurement strategy at presentation to the emergency department: The SAFETY Study

Fabre-Estremera, Blanca, Smith, Stephen W., Sandoval, Yader, Schulz, Karen, Okeson, Brynn, Cullen, Louise and Apple, Fred S. (2023). Rapid rule-out of myocardial infarction using a single high-sensitivity cardiac troponin I measurement strategy at presentation to the emergency department: The SAFETY Study. Clinical Chemistry, 69 (6), 627-636. doi: 10.1093/clinchem/hvad033

Rapid rule-out of myocardial infarction using a single high-sensitivity cardiac troponin I measurement strategy at presentation to the emergency department: The SAFETY Study

2023

Journal Article

Snapshot of suspected acute coronary syndrome assessment processes in the emergency department: A national cross‐sectional survey

Brownlee, Emily, Greenslade, Jaimi H, Kelly, Anne‐Maree, Meek, Robert A, Parsonage, William A and Cullen, Louise (2023). Snapshot of suspected acute coronary syndrome assessment processes in the emergency department: A national cross‐sectional survey. Emergency Medicine Australasia, 35 (2), 261-268. doi: 10.1111/1742-6723.14115

Snapshot of suspected acute coronary syndrome assessment processes in the emergency department: A national cross‐sectional survey

2023

Journal Article

Sex differences in epidemiology, care, and outcomes in patients with acute chest pain

Dawson, Luke P., Nehme, Emily, Nehme, Ziad, Davis, Esther, Bloom, Jason, Cox, Shelley, Nelson, Adam J., Okyere, Daniel, Anderson, David, Stephenson, Michael, Lefkovits, Jeffrey, Taylor, Andrew J., Nicholls, Stephen J., Cullen, Louise, Kaye, David, Smith, Karen and Stub, Dion (2023). Sex differences in epidemiology, care, and outcomes in patients with acute chest pain. Journal of the American College of Cardiology, 81 (10), 933-945. doi: 10.1016/j.jacc.2022.12.025

Sex differences in epidemiology, care, and outcomes in patients with acute chest pain

2023

Journal Article

Acute cardiovascular care in the Emergency Department and beyond: a call for interdisciplinary collaboration in clinical research

Platz, Elke, Morrow, David A, Verbrugge, Frederik H, Vranckx, Pascal and Cullen, Louise (2023). Acute cardiovascular care in the Emergency Department and beyond: a call for interdisciplinary collaboration in clinical research. European Heart Journal. Acute Cardiovascular Care, 12 (2), 77-79. doi: 10.1093/ehjacc/zuac170

Acute cardiovascular care in the Emergency Department and beyond: a call for interdisciplinary collaboration in clinical research

2023

Journal Article

Chest pain management using prehospital point-of-care troponin and paramedic risk assessment

Dawson, Luke P., Nehme, Emily, Nehme, Ziad, Zomer, Ella, Bloom, Jason, Cox, Shelley, Anderson, David, Stephenson, Michael, Ball, Jocasta, Zhou, Jennifer, Lefkovits, Jeffrey, Taylor, Andrew J., Horrigan, Mark, Chew, Derek P., Kaye, David, Cullen, Louise, Mihalopoulos, Cathrine, Smith, Karen and Stub, Dion (2023). Chest pain management using prehospital point-of-care troponin and paramedic risk assessment. JAMA Internal Medicine, 183 (3), 203-211. doi: 10.1001/jamainternmed.2022.6409

Chest pain management using prehospital point-of-care troponin and paramedic risk assessment

2022

Journal Article

Single high-sensitivity point of care whole blood cardiac troponin I measurement to rule out acute myocardial infarction at low risk

Apple, Fred S., Smith, Stephen W., Greenslade, Jaimi H., Sandoval, Yader, Parsonage, William, Ranasinghe, Isuru, Gaikwad, Niranjan J, Schulz, Karen, Stephensen, Laura, Schmidt, Christian W., Okeson, Brynn and Cullen, Louise (2022). Single high-sensitivity point of care whole blood cardiac troponin I measurement to rule out acute myocardial infarction at low risk. Circulation, 146 (25), 1918-1929. doi: 10.1161/circulationaha.122.061148

Single high-sensitivity point of care whole blood cardiac troponin I measurement to rule out acute myocardial infarction at low risk

2022

Journal Article

Diagnostic and prognostic performance of the ratio between high-sensitivity cardiac troponin I and troponin T in patients with chest pain

Eggers, Kai M., Hammarsten, Ola, Aldous, Sally J., Cullen, Louise, Greenslade, Jaimi H., Lindahl, Bertil, Parsonage, William A., Pemberton, Christopher J., Pickering, John W., Richards, A. Mark, Troughton, Richard W. and Than, Martin P. (2022). Diagnostic and prognostic performance of the ratio between high-sensitivity cardiac troponin I and troponin T in patients with chest pain. PLoS One, 17 (11) e0276645, 1-14. doi: 10.1371/journal.pone.0276645

Diagnostic and prognostic performance of the ratio between high-sensitivity cardiac troponin I and troponin T in patients with chest pain