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2014 Book Chapter Hepatitis C VirusThompson, A. J., Clark, P. and Aghemo, A. (2014). Hepatitis C Virus. Handbook of Pharmacogenomics and Stratified Medicine. (pp. 859-877) edited by Sandosh Padmanabhan . London, UK: Academic Press. doi: 10.1016/B978-0-12-386882-4.00037-2 |
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2013 Journal Article Predictors of consent to pharmacogenomics testing in the IDEAL studyJazwinski, Alison B., Clark, Paul J., Thompson, Alexander J., Gordon, Stuart C., Lawitz, Eric J., Noviello, Stephanie, Brass, Clifford A., Pedicone, Lisa D., Albrecht, Janice K., Sulkowski, Mark S. and Muir, Andrew J. (2013). Predictors of consent to pharmacogenomics testing in the IDEAL study. Pharmacogenetics and Genomics, 23 (11), 619-623. doi: 10.1097/FPC.0000000000000002 |
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2013 Conference Publication ITPA genotype predicts the development of on-treatment anaemia after 4 weeks of protease inhibitor therapy irrespective of fibrosis stage and past treatment experience status: A multi-centre real-life experienceHolmes, J. A., Mangia, A., Clark, P. J., Iser, D. M., Nguyen, T., Bell, S. J., Ryan, M., Bonanzinga, S., Desmond, P. V., Petruzzellis, D., Bowden, D. S. and Thompson, A. J. (2013). ITPA genotype predicts the development of on-treatment anaemia after 4 weeks of protease inhibitor therapy irrespective of fibrosis stage and past treatment experience status: A multi-centre real-life experience. HOBOKEN: WILEY-BLACKWELL. |
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2013 Conference Publication ITPA ACTIVITY PREDICTS Hb DECLINE AFTER FOUR WEEKS OF PI TRIPLE THERAPY, REGARDLESS OF PREVIOUS TREATMENT OR NAIVE STATUS AND FIBROSIS: A MULTICENTER REAL-LIFE EXPERIENCEMangia, A., Clark, P. J., Piazzolla, V., Santoro, R., Holmes, J. A., Mottola, L., Ripoli, M., Iser, D., Nguyen, T., Bell, S. J., Desmond, P. V., Petruzzellis, D., Patel, K., Muir, A. J. and Thompson, A. J. (2013). ITPA ACTIVITY PREDICTS Hb DECLINE AFTER FOUR WEEKS OF PI TRIPLE THERAPY, REGARDLESS OF PREVIOUS TREATMENT OR NAIVE STATUS AND FIBROSIS: A MULTICENTER REAL-LIFE EXPERIENCE. International Liver Congress / 48th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL), Amsterdam Netherlands, Apr 24-28, 2013. AMSTERDAM: ELSEVIER SCIENCE BV. |
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2013 Journal Article Inosine triphosphatase deficiency helps predict anaemia, anaemia management and response in chronic hepatitis C therapyClark, P. J., Aghemo, A., Degasperi, E., Galmozzi, E., Urban, T. J., Vock, D. M., Patel, K., Thompson, A. J., Rumi, M. G., D'Ambrosio, R., Muir, A. J. and Colombo, M. (2013). Inosine triphosphatase deficiency helps predict anaemia, anaemia management and response in chronic hepatitis C therapy. Journal of Viral Hepatitis, 20 (12), 858-866. doi: 10.1111/jvh.12113 |
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2012 Journal Article Search for anomalous production of prompt like-sign lepton pairs at √<i>s</i>=7 TeV with the ATLAS detectorAad, G., Abajyan, T., Abbott, B., Abdallah, J., Khalek, S. Abdel, Abdelalim, A. A., Abdinov, O., Aben, R., Abi, B., Abolins, M., AbouZeid, O. S., Abramowicz, H., Abreu, H., Acerbi, E., Acharya, B. S., Adamczyk, L., Adams, D. L., Addy, T. N., Adelman, J., Adomeit, S., Adragna, P., Adye, T., Aefsky, S., Aguilar-Saavedra, J. A., Agustoni, M., Aharrouche, M., Ahlen, S. P., Ahles, F., Ahmad, A. ... Zwalinski, L. (2012). Search for anomalous production of prompt like-sign lepton pairs at √s=7 TeV with the ATLAS detector. Journal of High Energy Physics, 2012 (12) 007. doi: 10.1007/JHEP12(2012)007 |
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2012 Journal Article Dysregulation of innate immunity in hepatitis C virus genotype 1 IL28B-unfavorable genotype patients: Impaired viral kinetics and therapeutic responseNaggie, Susanna, Osinusi, Anu, Katsounas, Antonios, Lempicki, Richard, Herrmann, Eva, Thompson, Alexander J., Clark, Paul J., Patel, Keyur, Muir, Andrew J., McHutchison, John G., Schlaak, Joerg F., Trippler, Martin, Shivakumar, Bhavana, Masur, Henry, Polis, Michael A. and Kottilil, Shyam (2012). Dysregulation of innate immunity in hepatitis C virus genotype 1 IL28B-unfavorable genotype patients: Impaired viral kinetics and therapeutic response. Hepatology, 56 (2), 444-454. doi: 10.1002/hep.25647 |
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2012 Journal Article The Association of Genetic Variants with Hepatic Steatosis in Patients with Genotype 1 Chronic Hepatitis C Infection (vol 57, pg 2213, 2012)Clark, Paul J., Thompson, Alexander J., Zhu, Qianqian, Vock, David M., Zhu, Mingfu, Patel, Keyur, Harrison, Stephen A., Naggie, Susanna, Ge, Dongliang, Tillmann, Hans L., Urban, Thomas J., Shianna, Kevin, Fellay, Jacques, Goodman, Zachary, Noviello, Stephanie, Pedicone, Lisa D., Afdhal, Nezam, Sulkowski, Mark, Albrecht, Janice K., Goldstein, David B., McHutchison, John G. and Muir, Andrew J. (2012). The Association of Genetic Variants with Hepatic Steatosis in Patients with Genotype 1 Chronic Hepatitis C Infection (vol 57, pg 2213, 2012). Digestive Diseases and Sciences, 57 (9), 2479-2479. doi: 10.1007/s10620-012-2309-y |
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2012 Journal Article Overcoming Barriers to Care for Hepatitis CClark, Paul J. and Muir, Andrew J. (2012). Overcoming Barriers to Care for Hepatitis C. New England Journal of Medicine, 366 (26), 2436-2438. doi: 10.1056/NEJMp1202608 |
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2012 Journal Article Interleukin 28B polymorphisms are the only common genetic variants associated with low-density lipoprotein cholesterol (LDL-C) in genotype-1 chronic hepatitis C and determine the association between LDL-C and treatment responseClark, P. J., Thompson, A. J., Zhu, M., Vock, D. M., Zhu, Q., Ge, D., Patel, K., Harrison, S. A., Urban, T. J., Naggie, S., Fellay, J., Tillmann, H. L., Shianna, K., Noviello, S., Pedicone, L. D., Esteban, R., Kwo, P., Sulkowski, M. S., Afdhal, N., Albrecht, J. K., Goldstein, D. B., McHutchison, J. G. and Muir, A. J. (2012). Interleukin 28B polymorphisms are the only common genetic variants associated with low-density lipoprotein cholesterol (LDL-C) in genotype-1 chronic hepatitis C and determine the association between LDL-C and treatment response. Journal of Viral Hepatitis, 19 (5), 332-340. doi: 10.1111/j.1365-2893.2011.01553.x |
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2012 Conference Publication Association of Serum Adipocytokines With IL28B and SVR in Chronic Hepatitis CClark, Paul J., Thompson, Alexander J., Jazwinski, Alison, Tillmann, Hans L., Naggie, Susanna, Muir, Andrew J. and Patel, Keyur (2012). Association of Serum Adipocytokines With IL28B and SVR in Chronic Hepatitis C. Digestive Disease Week (DDW), San Diego Ca, May 19-22, 2012. PHILADELPHIA: W B SAUNDERS CO-ELSEVIER INC. |
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2012 Journal Article Elevated serum CK18 levels in chronic hepatitis C patients are associated with advanced fibrosis but not steatosisJazwinski, A. B., Thompson, A. J., Clark, P. J., Naggie, S., Tillmann, H. L. and Patel, K. (2012). Elevated serum CK18 levels in chronic hepatitis C patients are associated with advanced fibrosis but not steatosis. Journal of Viral Hepatitis, 19 (4), 278-282. doi: 10.1111/j.1365-2893.2011.01546.x |
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2012 Journal Article Reply to "IL28B polymorphism and hepatitis C: A genetic marker of peginterferon-alpha sensitivity devoid from classical interferon-alpha side effects?"Thompson, A. J., Clark, P. J., Muir, A. J. and Sulkowski, M. S. (2012). Reply to "IL28B polymorphism and hepatitis C: A genetic marker of peginterferon-alpha sensitivity devoid from classical interferon-alpha side effects?". Journal of Hepatology, 56 (3), 742-743. doi: 10.1016/j.jhep.2011.08.011 |
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2012 Journal Article Genome-wide association study of interferon-related cytopenia in chronic hepatitis C patientsThompson, Alexander J., Clark, Paul J., Singh, Abanish, Ge, Dongliang, Fellay, Jacques, Zhu, Mingfu, Zhu, Qianqian, Urban, Thomas J., Patel, Keyur, Tillmann, Hans L., Naggie, Susanna, Afdhal, Nezam H., Jacobson, Ira M., Esteban, Rafael, Poordad, Fred, Lawitz, Eric J., McCone, Jonathan, Shiffman, Mitchell L., Galler, Greg W., King, John W., Kwo, Paul Y., Shianna, Kevin V., Noviello, Stephanie, Pedicone, Lisa D., Brass, Clifford A., Albrecht, Janice K., Sulkowski, Mark S., Goldstein, David B., McHutchison, John G. and Muir, Andrew J. (2012). Genome-wide association study of interferon-related cytopenia in chronic hepatitis C patients. Journal of Hepatology, 56 (2), 313-319. doi: 10.1016/j.jhep.2011.04.021 |
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2012 Journal Article Variants in the ITPA gene protect against ribavirin-induced hemolytic anemia in HIV/HCV-coinfected patients with all HCV genotypesNaggie, Susanna, Rallon, Norma I., Benito, Jose M., Morello, Judith, Rodriguez-Novoa, Sonia, Clark, Paul J., Thompson, Alexander J., Shianna, Kevin V., Vispo, Eugenia, McHutchison, John G., Goldstein, David B. and Soriano, Vincent (2012). Variants in the ITPA gene protect against ribavirin-induced hemolytic anemia in HIV/HCV-coinfected patients with all HCV genotypes. Journal of Infectious Diseases, 205 (3), 376-383. doi: 10.1093/infdis/jir754 |
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2012 Journal Article The association of genetic variants with hepatic steatosis in patients with genotype 1 chronic Hepatitis C infectionClark, Paul J., Thompson, Alexander J., Zhu, Qianqian, Vock, David M., Zhu, Mingfu, Patel, Keyur, Harrison, Stephen A., Naggie, Susanna, Ge, Dongliang, Tillmann, Hans L., Urban, Thomas J., Shianna, Kevin, Fellay, Jacques, Goodman, Zachary, Noviello, Stephanie, Pedicone, Lisa D., Afdhal, Nezam, Sulkowski, Mark, Albrecht, Janice K., Goldstein, David B., McHutchison, John G. and Muir, Andrew J. (2012). The association of genetic variants with hepatic steatosis in patients with genotype 1 chronic Hepatitis C infection. Digestive Diseases and Sciences, 57 (8), 2213-2221. doi: 10.1007/s10620-012-2171-y |
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2012 Conference Publication Optimizing ribavirin dose is critical for sustained viral response in patients with thalassemia major treated for chronic hepatitis CClark, Paul J., Santoro, Rosanna, Piazzolla, Valeria, Mottola, Leonardo, Bacca, D., Dello Iacono, N., Grimaldi, Salvatore, Quarta, Antonella, Urban, Thomas J., Naggie, Susanna, Patel, Keyur, Thompson, Alexander J., Muir, Andrew J. and Mangia, Alessandra (2012). Optimizing ribavirin dose is critical for sustained viral response in patients with thalassemia major treated for chronic hepatitis C. 63rd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), Boston Ma, Nov 09-13, 2012. HOBOKEN: WILEY-BLACKWELL. |
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2012 Journal Article Systemic thrombolysis for acute, severe Budd-Chiari syndromeClark, P.J., Slaughter, R.E. and Radford, D.J. (2012). Systemic thrombolysis for acute, severe Budd-Chiari syndrome. Journal of Thrombosis and Thrombolysis, 34 (3), 410-415. doi: 10.1007/s11239-012-0760-4 |
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2012 Journal Article Hepatitis C virus selectively perturbs the distal cholesterol synthesis pathway in a genotype-specific mannerClark, Paul J., Thompson, Alexander J., Vock, David M., Kratz, Lisa E., Tolun, Adviye A., Muir, Andrew J., Mchutchison, John G., Subramanian, Mani, Millington, David M., Kelley, Richard I. and Patel, Keyur (2012). Hepatitis C virus selectively perturbs the distal cholesterol synthesis pathway in a genotype-specific manner. Hepatology, 56 (1), 49-56. doi: 10.1002/hep.25631 |
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2012 Conference Publication Itpa Variants Predict Treatment-Induced Anemia and the Need for Ribavirin Dose Reduction and Erythropoietin SupportClark, P. J., Aghemo, A., Degasperi, E., Galmozzi, E., Thompson, A. J., Patel, K., Rumi, M. Grazia, Prati, G. M., Muir, A. J. and Colombo, M. (2012). Itpa Variants Predict Treatment-Induced Anemia and the Need for Ribavirin Dose Reduction and Erythropoietin Support. 47th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL), Barcelona Spain, Apr 18-22, 2012. AMSTERDAM: ELSEVIER SCIENCE BV. doi: 10.1016/S0168-8278(12)61111-8 |
