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2015

Journal Article

ELF score ≥9.8 indicates advanced hepatic fibrosis and is influenced by age, steatosis and histological activity

Fagan, Kevin J., Pretorius, Carel J., Horsfall, Leigh U., Irvine, Katharine M., Wilgen, Urs, Choi, Kihoon, Fletcher, Linda M., Tate, Jill, Melino, Michelle, Nusrat, Sharmin, Miller, Gregory C., Clouston, Andrew D., Ballard, Emma, O'Rourke, Peter, Lampe, Guy, Ungerer, Jacobus P. J. and Powell, Elizabeth E. (2015). ELF score ≥9.8 indicates advanced hepatic fibrosis and is influenced by age, steatosis and histological activity. Liver International, 35 (6), 1673-1681. doi: 10.1111/liv.12760

ELF score ≥9.8 indicates advanced hepatic fibrosis and is influenced by age, steatosis and histological activity

2015

Journal Article

Systematic review: unmet supportive care needs in people diagnosed with chronic liver disease

Valery, Patricia C., Powell, Elizabeth, Moses, Neta, Volk, Michael L., McPhail, Steven M., Clark, Paul J. and Martin, Jennifer (2015). Systematic review: unmet supportive care needs in people diagnosed with chronic liver disease. BMJ Open, 5 (4) e007451, 1-16. doi: 10.1136/bmjopen-2014-007451

Systematic review: unmet supportive care needs in people diagnosed with chronic liver disease

2015

Journal Article

Ascites bacterial burden and immune cell profile are associated with poor clinical outcomes in the absence of overt infection

Fagan, Kevin J., Rogers, Geraint B., Melino, Michelle, Arthur, Dionne M., Costello, Mary-Ellen, Morrison, Mark, Powell, Elizabeth E. and Irvine, Katharine M. (2015). Ascites bacterial burden and immune cell profile are associated with poor clinical outcomes in the absence of overt infection. PLoS One, 10 (3) e0120642, e0120642. doi: 10.1371/journal.pone.0120642

Ascites bacterial burden and immune cell profile are associated with poor clinical outcomes in the absence of overt infection

2015

Journal Article

Interferon-λ rs12979860 genotype and liver fibrosis in viral and non-viral chronic liver disease

Eslam, Mohammed, Hashem, Ahmed M, Leung, Reynold, Romero-Gomez, Manuel, Berg, Thomas, Dore, Gregory J, Chan, Henry L.K, Irving, William L, Sheridan, David, Abate, Maria L, Adams, Leon A, Mangia, Alessandra, Weltman, Martin, Bugianesi, Elisabetta, Spengler, Ulrich, Shaker, Olfat, Fischer, Janett, Mollison, Lindsay, Cheng, Wendy, Powell, Elizabeth, Nattermann, Jacob, Riordan, Stephen, McLeod, Duncan, Armstrong, Nicola J, Douglas, Mark W, Liddle, Christopher, Booth, David R, George, Jacob, Ahlenstiel, Golo ... Santaro, Rosanna (2015). Interferon-λ rs12979860 genotype and liver fibrosis in viral and non-viral chronic liver disease. Nature Communications, 6 (6422) 6422. doi: 10.1038/ncomms7422

Interferon-λ rs12979860 genotype and liver fibrosis in viral and non-viral chronic liver disease

2015

Conference Publication

Discrepancies in the use of medications in patients with cirrhosis

Hayward, K., Valery, P. C., Cottrell, N., Irvine, K., Horsfall, L., Ruffin, B., Tallis, C., Chachay, V., Martin, J. and Powell, E. (2015). Discrepancies in the use of medications in patients with cirrhosis. GESA-AGW and WGO International Congress, Gastroenterological Society of Australia Australian Gastroenterology Week, Brisbane, QLD Australia, 28 September - 2 October 2015. Richmond, VIC Australia: Wiley-Blackwell. doi: 10.1111/jgh.13093

Discrepancies in the use of medications in patients with cirrhosis

2015

Conference Publication

Predicting clinical outcomes in chronic liver disease: the ELF test is superior to histology and simple scores

Irvine, K. M., Wockner, L. F., Shanker, M., Fagan, K. J., Horsfall, L. U., Fletcher, L. M., Ungerer, J., Pretorius, C. J., Miller, G. C., Clouston, A. D., Lampe, G. and Powell, E. E. (2015). Predicting clinical outcomes in chronic liver disease: the ELF test is superior to histology and simple scores. Gastro 2015 GESA-AGW and WGO International Congress, Gastroenterological Society of Australia Australian Gastroenterology Week 2015 | World Congress of Gastroenterology, Brisbane, QLD, Australia, 28 September-2 October 2015. Richmond, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.13093

Predicting clinical outcomes in chronic liver disease: the ELF test is superior to histology and simple scores

2015

Conference Publication

Blocking Wnt protein secretion from macrophages exacerbates liver fibrosis and hepatic progenitor cell activation

Irvine, K. M., Clouston, A. D., Blumenthal, A. and Powell, E. E. (2015). Blocking Wnt protein secretion from macrophages exacerbates liver fibrosis and hepatic progenitor cell activation. GESA-AGW and WGO International Congress, Gastroenterological Society of Australia Australian Gastroenterology Week, Brisbane, QLD, Australia, 28 September - 2 October 2015. Richmond, VIC, Australia: Wiley-Blackwell. doi: 10.1111/jgh.13087

Blocking Wnt protein secretion from macrophages exacerbates liver fibrosis and hepatic progenitor cell activation

2015

Conference Publication

Deletion of Wntless in macrophages exacerbates liver fibrosis and the ductular reaction in chronic liver injury

Irvine, Katharine, Clouston, Andrew D., Blumenthal, Antje and Powell, Elizabeth E. (2015). Deletion of Wntless in macrophages exacerbates liver fibrosis and the ductular reaction in chronic liver injury. 66th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD), San Francisco, United States, Nov 13-17, 2015. Hoboken, United States: John Wiley & Sons.

Deletion of Wntless in macrophages exacerbates liver fibrosis and the ductular reaction in chronic liver injury

2015

Conference Publication

Predicting clinical outcomes in chronic liver disease: the ELF test is superior to histology and simple scores

Irvine, Katharine, Wockner, Leesa F., Shanker, Mihir, Fagan, Kevin, Horsfall, Leigh, Fletcher, Linda, Ungerer, Jacobus, Pretorius, Carel J., Miller, Gregory, Clouston, Andrew D., Lampe, Guy and Powell, Elizabeth E. (2015). Predicting clinical outcomes in chronic liver disease: the ELF test is superior to histology and simple scores. 66th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD), San Francisco, CA, United States, 13-17 November 2015. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/hep.28218

Predicting clinical outcomes in chronic liver disease: the ELF test is superior to histology and simple scores

2015

Conference Publication

Patterns of service utilisation within hepatology clinics: high prevalence of advanced liver disease

El-Atem, N., Wojcik, K., Horsfall, L., Irvine, K., Johnson, T., Mcphail, S. M. and Powell, E. E. (2015). Patterns of service utilisation within hepatology clinics: high prevalence of advanced liver disease. Gastro 2015 GESA-AGW and WGO International Congress, Gastroenterological Society of Australia Australian Gastroenterology Week 2015 | World Congress of Gastroenterology, Brisbane, Queensland, Australia, 28 September-2 October 2015. Richmond, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.13093

Patterns of service utilisation within hepatology clinics: high prevalence of advanced liver disease

2015

Conference Publication

Economic consideration for reducing hospital presentations among patients with decompensated cirrhosis: not all presentations avoided can be considered equal

Mcphail, S. M., Horsfall, L., Irvine, K., Fagan, K. J. and Powell, E. E. (2015). Economic consideration for reducing hospital presentations among patients with decompensated cirrhosis: not all presentations avoided can be considered equal. Gastro 2015 GESA-AGW and WGO International Congress, Gastroenterological Society of Australia Australian Gastroenterology Week 2015 World Congress of Gastroenterology, Brisbane, Queensland, Australia, 28 September-2 October 2015. Richmond, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.13093

Economic consideration for reducing hospital presentations among patients with decompensated cirrhosis: not all presentations avoided can be considered equal

2014

Journal Article

Senescent human hepatocytes express a unique secretory phenotype and promote macrophage migration

Irvine, Katharine M., Skoien, Richard, Bokil, Nilesh J., Melino, Michelle, Thomas, Gethin P., Loo, Dorothy, Gabrielli, Brian, Hill, Michelle M., Sweet, Matthew J., Clouston, Andrew D. and Powell, Elizabeth E. (2014). Senescent human hepatocytes express a unique secretory phenotype and promote macrophage migration. World Journal of Gastroenterology, 20 (47), 17851-17862. doi: 10.3748/wjg.v20.i47.17851

Senescent human hepatocytes express a unique secretory phenotype and promote macrophage migration

2014

Conference Publication

An ELF score of >= 9.8 can identify advanced fibrosis in Australian patients with chronic liver disease

Fagan, K., Horsfall, L., Irvine, K., Fletcher, L., Tate, J., Choi, K., Nusrat, S., Melino, M., Clouston, A., Ballard, E., O'Rourke, P., Lampe, G., Ungerer, J. and Powell, E. (2014). An ELF score of >= 9.8 can identify advanced fibrosis in Australian patients with chronic liver disease. Australian Gastroenterology Week 2014, UnknownGold Coast Convention & Exhibition Centre, Broadbeach, Queensland, 22-24 October. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia.

An ELF score of >= 9.8 can identify advanced fibrosis in Australian patients with chronic liver disease

2014

Journal Article

Burden of decompensated cirrhosis and ascites on hospital services in a tertiary care facility: time for change?

Fagan, K. J., Zhao, Eileen Y., Horsfall, L. U., Ruffin, Brittany J., Kruger, Mark S., McPhail, S. M., O'Rourke, Peter, Ballard, Emma, Irvine, K. M. and Powell, E. E. (2014). Burden of decompensated cirrhosis and ascites on hospital services in a tertiary care facility: time for change?. Internal Medicine Journal, 44 (9), 865-872. doi: 10.1111/imj.12491

Burden of decompensated cirrhosis and ascites on hospital services in a tertiary care facility: time for change?

2014

Journal Article

Diagnostic sensitivity of carbohydrate deficient transferrin in heavy drinkers

Fagan K.J., Irvine K.M., McWhinney B.C., Fletcher L.M., Horsfall L.U., Johnson L., O'Rourke P., Martin J., Scott I., Pretorius C.J., Ungerer J.P.J. and Powell E.E. (2014). Diagnostic sensitivity of carbohydrate deficient transferrin in heavy drinkers. BMC Gastroenterology, 14 (1) 97, 1-6. doi: 10.1186/1471-230X-14-97

Diagnostic sensitivity of carbohydrate deficient transferrin in heavy drinkers

2014

Journal Article

The portal inflammatory infiltrate and ductular reaction in human nonalcoholic fatty liver disease

Gadd, Victoria L., Skoien, Richard, Powell, Elizabeth E., Fagan, Kevin J., Winterford, Clay, Horsfall, Leigh, Irvine, Katharine and Clouston, Andrew D. (2014). The portal inflammatory infiltrate and ductular reaction in human nonalcoholic fatty liver disease. Hepatology, 59 (4), 1393-1405. doi: 10.1002/hep.26937

The portal inflammatory infiltrate and ductular reaction in human nonalcoholic fatty liver disease

2014

Conference Publication

Spaciotemporal characterization of the cellular and molecular contributors to chronic hepatic fibrosis in a hepatotoxin-induced mouse model

Melino, M., Gadd, V., Martinez, M., Lineburg, K., Irvine, K., Clouston, A. D., Powell, E. E. and Macdonald, K. P. (2014). Spaciotemporal characterization of the cellular and molecular contributors to chronic hepatic fibrosis in a hepatotoxin-induced mouse model. Australian Gastroenterology Week 2014, Broadbeach, QLD Australia, 22-24 October 2014. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.12736

Spaciotemporal characterization of the cellular and molecular contributors to chronic hepatic fibrosis in a hepatotoxin-induced mouse model

2014

Conference Publication

Microbial burden is associated with clinical outcomes and reduced ascites innate immune cells in non-infected ascites

Fagan, K. J., Melino, M., Powell, E. E. and Irvine, K. M. (2014). Microbial burden is associated with clinical outcomes and reduced ascites innate immune cells in non-infected ascites. Australian Gastroenterology Week 2014, Broadbeach, QLD Australia, 22-24 October 2014. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.12736_5

Microbial burden is associated with clinical outcomes and reduced ascites innate immune cells in non-infected ascites

2014

Journal Article

New paradigms in the histopathology of NAFLD

Clouston, Andrew D., Gadd, Victoria L., Irvine, Katharine M. and Powell, Elizabeth E. (2014). New paradigms in the histopathology of NAFLD. Current Hepatitis Reports, 13 (2), 81-87. doi: 10.1007/s11901-014-0214-x

New paradigms in the histopathology of NAFLD

2013

Journal Article

Assessment of alcohol histories obtained from patients with liver disease: opportunities to improve early intervention

Fagan, K. J., Irvine, K. M., Kumar, S., Bates, A., Horsfall, L. U., Feeney, G. F. and Powell, E. E. (2013). Assessment of alcohol histories obtained from patients with liver disease: opportunities to improve early intervention. Internal Medicine Journal, 43 (10), 1096-1102. doi: 10.1111/imj.12229

Assessment of alcohol histories obtained from patients with liver disease: opportunities to improve early intervention