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2007

Journal Article

Toward the development of prophylactic and therapeutic human papillomavirus type-16 lipopeptide vaccines

Moyle, Peter M., Olive, Colleen, Ho, Mei-Fong, Pandey, Manisha, Dyer, Joanne, Suhrbier, Andreas, Fujita, Yoshio and Toth, Istvan (2007). Toward the development of prophylactic and therapeutic human papillomavirus type-16 lipopeptide vaccines. Journal of Medicinal Chemistry, 50 (19), 4721-4727. doi: 10.1021/jm070287b

Toward the development of prophylactic and therapeutic human papillomavirus type-16 lipopeptide vaccines

2007

Journal Article

The anti-mutagenic and antioxidant effects of bile pigments in the Ames Salmonella test

Bulmer, A., Ried, K., Coombes, J., Blanchfield, J., Toth, I. and Wagner, K. (2007). The anti-mutagenic and antioxidant effects of bile pigments in the Ames Salmonella test. Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 629 (2), 122-132. doi: 10.1016/j.mrgentox.2007.01.008

The anti-mutagenic and antioxidant effects of bile pigments in the Ames Salmonella test

2007

Journal Article

Comparison of the in vitro apparent permeability and stability of opioid mimetic compounds with that of the native peptide

Koda, Y., Shiotani, K., Toth, I., Tsuda, Y., Okada, Y. and Blanchfield, J. (2007). Comparison of the in vitro apparent permeability and stability of opioid mimetic compounds with that of the native peptide. Bioorganic & Medicinal Chemistry Letters, 17 (7), 2043-2046. doi: 10.1016/j.bmcl.2007.01.051

Comparison of the in vitro apparent permeability and stability of opioid mimetic compounds with that of the native peptide

2007

Journal Article

Permeability studies of Kavalactones using a Caco-2 cell monolayer model

Matthias, A., Blanchfield, J., Penman, K., Bone, K., Toth, I. and Lehmann, R. (2007). Permeability studies of Kavalactones using a Caco-2 cell monolayer model. Journal of Clinical Pharmacy and Therapeutics, 32 (3), 233-239. doi: 10.1111/j.1365-2710.2007.00810.x

Permeability studies of Kavalactones using a Caco-2 cell monolayer model

2007

Conference Publication

Enhancement of Oral Drug Absorption - Effect of Lipid and Glycoside Conjugation on the Enzymatic Stability and Intestinal Permeability of IM862

Bergeon, J., Chan, Y. and Toth, I. (2007). Enhancement of Oral Drug Absorption - Effect of Lipid and Glycoside Conjugation on the Enzymatic Stability and Intestinal Permeability of IM862. 4th International Peptide Symposium, Cairns QLD Australia, 21-25 October 2007. Australia: Australian Peptide Association.

Enhancement of Oral Drug Absorption - Effect of Lipid and Glycoside Conjugation on the Enzymatic Stability and Intestinal Permeability of IM862

2007

Conference Publication

Peptide-lipid-carbohydrate based vaccine against group A Streptococcal infection.

Simerska, P., Abdel-Aal, A. B., McGeary, R., Moyle, P.M., Fujita, Y., Good, M.F. and Toth, I. (2007). Peptide-lipid-carbohydrate based vaccine against group A Streptococcal infection.. 13th International Congress of Immunology, Rio de Janeiro, Brazil, August 21-25.

Peptide-lipid-carbohydrate based vaccine against group A Streptococcal infection.

2007

Journal Article

Modified Influenza Virosomes: Recent Advances and Potential in Gene Delivery

Khoshnejad, M., Young, P. R., Toth, I. and Minchin, R. F. (2007). Modified Influenza Virosomes: Recent Advances and Potential in Gene Delivery. Current Medicinal Chemistry, 14 (29), 3152-3156. doi: 10.2174/092986707782793989

Modified Influenza Virosomes: Recent Advances and Potential in Gene Delivery

2007

Journal Article

Enhanced protection against Streptococcus pyogenes infection by intranasal vaccination with a dual antigen component M protein/SfbI lipid core peptide vaccine formulation

Olive, C., Schulze, K., Sun, H. K., Ebensen, T., Horváth, A., Toth, I. and Guzman, C. A. (2007). Enhanced protection against Streptococcus pyogenes infection by intranasal vaccination with a dual antigen component M protein/SfbI lipid core peptide vaccine formulation. Vaccine, 25 (10), 1789-1797. doi: 10.1016/j.vaccine.2006.11.031

Enhanced protection against Streptococcus pyogenes infection by intranasal vaccination with a dual antigen component M protein/SfbI lipid core peptide vaccine formulation

2007

Conference Publication

Development of a Multivalent Heteroepitopic Group A Streptococcus Vaccine

Fujita, Y., Moyle, P., Abdel-Aal, A., Batzloff, M., Good, M. and Toth, I. (2007). Development of a Multivalent Heteroepitopic Group A Streptococcus Vaccine. 4th International Peptide Symposium, Cairns, 21-25 October 2007. Australia: Australian Peptide Association.

Development of a Multivalent Heteroepitopic Group A Streptococcus Vaccine

2007

Conference Publication

Vaccine delivery: Synthesis and investigation of a highly pure, multi-epitopic lipopeptide vaccine candidate

Toth, I., Moyle, P. M., Simerska, P., Fujita, Y., Olive, C. and Good, M. F. (2007). Vaccine delivery: Synthesis and investigation of a highly pure, multi-epitopic lipopeptide vaccine candidate. 20th American Peptide Symposium, Montréal, Quebec, Canada, 26-30 June 2007. HOBOKEN: Wiley Periodicals. doi: 10.1002/bip.20783

Vaccine delivery: Synthesis and investigation of a highly pure, multi-epitopic lipopeptide vaccine candidate

2007

Journal Article

A védőoltások gyógyszerkémiájának egyik legújabb fejezete. Zsír-aminosav komplexen alapuló vakcinák (Recent developments in prophylactic drug chemistry. Vaccines based on fatty-amino acid complexes)

Toth, I. (2007). A védőoltások gyógyszerkémiájának egyik legújabb fejezete. Zsír-aminosav komplexen alapuló vakcinák (Recent developments in prophylactic drug chemistry. Vaccines based on fatty-amino acid complexes). Magyar kémikusok lapja, 62, 274-276.

A védőoltások gyógyszerkémiájának egyik legújabb fejezete. Zsír-aminosav komplexen alapuló vakcinák (Recent developments in prophylactic drug chemistry. Vaccines based on fatty-amino acid complexes)

2007

Conference Publication

The importance of epitope and lipid orientation in the design of synthetic self-adjuvanting group A streptococcal (GAS) vaccine

Abdel-Aal, A. M., Batzloff, M. R., Faria, A., Fujita, Y., Good, M. F., Phillipps, K. S. M., Simerska, P., Toth, I. and Zaman, M. (2007). The importance of epitope and lipid orientation in the design of synthetic self-adjuvanting group A streptococcal (GAS) vaccine. 4th international Peptide Symposium in conjunction with the 7th Australian Peptide Conference and the 2nd Asia-Pacific International Peptide Symposium, 2007, Cairns, Queensland, Australia, 21 - 25 October 2007. Australian Peptide Association.

The importance of epitope and lipid orientation in the design of synthetic self-adjuvanting group A streptococcal (GAS) vaccine

2007

Conference Publication

The Characterisation of Novel Dendritic Carriers with DNA by Isothermal Titration Calorimetry

Coles, D., Yang, S., Esposito, A., Mitchell, D., Minchin, R. and Toth, I. (2007). The Characterisation of Novel Dendritic Carriers with DNA by Isothermal Titration Calorimetry. 4th International Peptide Symposium, Cairns, 21-25 October 2007. Australia: Australian Peptide Association.

The Characterisation of Novel Dendritic Carriers with DNA by Isothermal Titration Calorimetry

2007

Conference Publication

Novel lipoamino acid based vaccine adjuvant carrier system

Toth, I., Moyle, P. M., Simerska, P., Fujita, Y., Olive, C. and Good, M. F. (2007). Novel lipoamino acid based vaccine adjuvant carrier system. International Congress of Immunology, Rio de Janeiro, Brazil, 21-25 August 2007. Toronto, Canada: Hogrefe & Huber.

Novel lipoamino acid based vaccine adjuvant carrier system

2007

Conference Publication

Liposaccharides in Peptide Vaccine Delivery

Simerska, P., Moyle, P. M., Abdel-Aal, A. M., Fujita, Y., Olive, C., Batzloff, M. R., Good, M. F. and Toth, I. (2007). Liposaccharides in Peptide Vaccine Delivery. 4th International Peptide Symposium, Cairns, 21-25 October 2007. Australia: Australian Peptide Association.

Liposaccharides in Peptide Vaccine Delivery

2007

Conference Publication

Vaccine Delivery Utilizing Liposaccharides

Simerska, P., Moyle, P. M., Zhong, W., McGeary, R., Abdel-Aal, A. B., Good, M. F. and Toth, I. (2007). Vaccine Delivery Utilizing Liposaccharides. 20th American Peptide Symposium, Montréal, Quebec, Canada, 26-30 June 2007. Hoboken: John Wiley & Sons. doi: 10.1002/bip.20783

Vaccine Delivery Utilizing Liposaccharides

2007

Journal Article

Design of bioavailable derivatives of 12-(3-adamantan-1-yl-ureido)dodecanoic acid, a potent inhibitor of the soluble epoxide hydrolase

Kim, I., Nishi, I., Tsai, H., Bradford, T., Koda, Y., Watanabe, T., Morriseau, C., Blanchfield, J., Toth, I. and Hammock, B. (2007). Design of bioavailable derivatives of 12-(3-adamantan-1-yl-ureido)dodecanoic acid, a potent inhibitor of the soluble epoxide hydrolase. Bioorganic & Medicinal Chemistry, 15 (1), 312-323. doi: 10.1016/j.bmc.2006.09.057

Design of bioavailable derivatives of 12-(3-adamantan-1-yl-ureido)dodecanoic acid, a potent inhibitor of the soluble epoxide hydrolase

2006

Conference Publication

Epidermal penetration of a therapeutic peptide by lipid conjugation; stereo-selective peptide availability of a topical diastereomeric lipopeptide

Caccetta, Rima, Blanchfield, Joanne T., Harrison, Jessica, Toth, Istvan and Benson, Heather A. E. (2006). Epidermal penetration of a therapeutic peptide by lipid conjugation; stereo-selective peptide availability of a topical diastereomeric lipopeptide. doi: 10.1007/s10989-006-9024-5

Epidermal penetration of a therapeutic peptide by lipid conjugation; stereo-selective peptide availability of a topical diastereomeric lipopeptide

2006

Journal Article

Method for the Synthesis of Multi-Epitopic Streptococcus pyogenes Lipopeptide Vaccines Using Native Chemical Ligation

Moyle, P. M., Olive, C., Ho, M. F., Burgess, M., Karpati, L., Good, M. F. and Toth, I. (2006). Method for the Synthesis of Multi-Epitopic Streptococcus pyogenes Lipopeptide Vaccines Using Native Chemical Ligation. Journal of Organic Chemistry, 71 (18), 6846-6850. doi: 10.1021/jo060960p

Method for the Synthesis of Multi-Epitopic Streptococcus pyogenes Lipopeptide Vaccines Using Native Chemical Ligation

2006

Journal Article

Lipidation and glycosylation of a T cell antigen receptor (TCR) transmembrane hvdrophobic peptide dramatically enhances in vitro and in vivo function

Amon, Michael A., Ali, Marina, Bender, Vera, Chan, Yiu-Ngok, Toth, Istvan and Manolios, Nicholas (2006). Lipidation and glycosylation of a T cell antigen receptor (TCR) transmembrane hvdrophobic peptide dramatically enhances in vitro and in vivo function. Biochimica Et Biophysica Acta-molecular Cell Research, 1763 (8), 879-888. doi: 10.1016/j.bbamcr.2006.04.013

Lipidation and glycosylation of a T cell antigen receptor (TCR) transmembrane hvdrophobic peptide dramatically enhances in vitro and in vivo function