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2007 Journal Article Design of bioavailable derivatives of 12-(3-adamantan-1-yl-ureido)dodecanoic acid, a potent inhibitor of the soluble epoxide hydrolaseKim, I., Nishi, I., Tsai, H., Bradford, T., Koda, Y., Watanabe, T., Morriseau, C., Blanchfield, J., Toth, I. and Hammock, B. (2007). Design of bioavailable derivatives of 12-(3-adamantan-1-yl-ureido)dodecanoic acid, a potent inhibitor of the soluble epoxide hydrolase. Bioorganic & Medicinal Chemistry, 15 (1), 312-323. doi: 10.1016/j.bmc.2006.09.057 |
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2007 Conference Publication Enhancement of Oral Drug Absorption - Effect of Lipid and Glycoside Conjugation on the Enzymatic Stability and Intestinal Permeability of IM862Bergeon, J., Chan, Y. and Toth, I. (2007). Enhancement of Oral Drug Absorption - Effect of Lipid and Glycoside Conjugation on the Enzymatic Stability and Intestinal Permeability of IM862. 4th International Peptide Symposium, Cairns QLD Australia, 21-25 October 2007. Australia: Australian Peptide Association. |
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2007 Conference Publication Peptide-lipid-carbohydrate based vaccine against group A Streptococcal infection.Simerska, P., Abdel-Aal, A. B., McGeary, R., Moyle, P.M., Fujita, Y., Good, M.F. and Toth, I. (2007). Peptide-lipid-carbohydrate based vaccine against group A Streptococcal infection.. 13th International Congress of Immunology, Rio de Janeiro, Brazil, August 21-25. |
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2007 Journal Article Modified Influenza Virosomes: Recent Advances and Potential in Gene DeliveryKhoshnejad, M., Young, P. R., Toth, I. and Minchin, R. F. (2007). Modified Influenza Virosomes: Recent Advances and Potential in Gene Delivery. Current Medicinal Chemistry, 14 (29), 3152-3156. doi: 10.2174/092986707782793989 |
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2007 Journal Article Enhanced protection against Streptococcus pyogenes infection by intranasal vaccination with a dual antigen component M protein/SfbI lipid core peptide vaccine formulationOlive, C., Schulze, K., Sun, H. K., Ebensen, T., Horváth, A., Toth, I. and Guzman, C. A. (2007). Enhanced protection against Streptococcus pyogenes infection by intranasal vaccination with a dual antigen component M protein/SfbI lipid core peptide vaccine formulation. Vaccine, 25 (10), 1789-1797. doi: 10.1016/j.vaccine.2006.11.031 |
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2007 Conference Publication Development of a Multivalent Heteroepitopic Group A Streptococcus VaccineFujita, Y., Moyle, P., Abdel-Aal, A., Batzloff, M., Good, M. and Toth, I. (2007). Development of a Multivalent Heteroepitopic Group A Streptococcus Vaccine. 4th International Peptide Symposium, Cairns, 21-25 October 2007. Australia: Australian Peptide Association. |
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2007 Conference Publication Vaccine delivery: Synthesis and investigation of a highly pure, multi-epitopic lipopeptide vaccine candidateToth, I., Moyle, P. M., Simerska, P., Fujita, Y., Olive, C. and Good, M. F. (2007). Vaccine delivery: Synthesis and investigation of a highly pure, multi-epitopic lipopeptide vaccine candidate. 20th American Peptide Symposium, Montréal, Quebec, Canada, 26-30 June 2007. HOBOKEN: Wiley Periodicals. doi: 10.1002/bip.20783 |
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2007 Journal Article A védőoltások gyógyszerkémiájának egyik legújabb fejezete. Zsír-aminosav komplexen alapuló vakcinák (Recent developments in prophylactic drug chemistry. Vaccines based on fatty-amino acid complexes)Toth, I. (2007). A védőoltások gyógyszerkémiájának egyik legújabb fejezete. Zsír-aminosav komplexen alapuló vakcinák (Recent developments in prophylactic drug chemistry. Vaccines based on fatty-amino acid complexes). Magyar kémikusok lapja, 62, 274-276. |
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2007 Conference Publication The importance of epitope and lipid orientation in the design of synthetic self-adjuvanting group A streptococcal (GAS) vaccineAbdel-Aal, A. M., Batzloff, M. R., Faria, A., Fujita, Y., Good, M. F., Phillipps, K. S. M., Simerska, P., Toth, I. and Zaman, M. (2007). The importance of epitope and lipid orientation in the design of synthetic self-adjuvanting group A streptococcal (GAS) vaccine. 4th international Peptide Symposium in conjunction with the 7th Australian Peptide Conference and the 2nd Asia-Pacific International Peptide Symposium, 2007, Cairns, Queensland, Australia, 21 - 25 October 2007. Australian Peptide Association. |
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2007 Conference Publication The Characterisation of Novel Dendritic Carriers with DNA by Isothermal Titration CalorimetryColes, D., Yang, S., Esposito, A., Mitchell, D., Minchin, R. and Toth, I. (2007). The Characterisation of Novel Dendritic Carriers with DNA by Isothermal Titration Calorimetry. 4th International Peptide Symposium, Cairns, 21-25 October 2007. Australia: Australian Peptide Association. |
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2006 Conference Publication Epidermal penetration of a therapeutic peptide by lipid conjugation; stereo-selective peptide availability of a topical diastereomeric lipopeptideCaccetta, Rima, Blanchfield, Joanne T., Harrison, Jessica, Toth, Istvan and Benson, Heather A. E. (2006). Epidermal penetration of a therapeutic peptide by lipid conjugation; stereo-selective peptide availability of a topical diastereomeric lipopeptide. doi: 10.1007/s10989-006-9024-5 |
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2006 Journal Article Method for the Synthesis of Multi-Epitopic Streptococcus pyogenes Lipopeptide Vaccines Using Native Chemical LigationMoyle, P. M., Olive, C., Ho, M. F., Burgess, M., Karpati, L., Good, M. F. and Toth, I. (2006). Method for the Synthesis of Multi-Epitopic Streptococcus pyogenes Lipopeptide Vaccines Using Native Chemical Ligation. Journal of Organic Chemistry, 71 (18), 6846-6850. doi: 10.1021/jo060960p |
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2006 Journal Article Intranasal administration is an effective mucosal vaccine delivery route for self-adjuvanting lipid core peptides targeting the group A streptococcal M proteinOlive, Colleen, Sun, Hsien Kuo, Ho, Mei‐Fong, Dyer, Joanne, Horvath, Aniko, Toth, Istvan and Good, Michael F. (2006). Intranasal administration is an effective mucosal vaccine delivery route for self-adjuvanting lipid core peptides targeting the group A streptococcal M protein. Journal of Infectious Diseases, 194 (3), 316-324. doi: 10.1086/505580 |
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2006 Journal Article Lipidation and glycosylation of a T cell antigen receptor (TCR) transmembrane hvdrophobic peptide dramatically enhances in vitro and in vivo functionAmon, Michael A., Ali, Marina, Bender, Vera, Chan, Yiu-Ngok, Toth, Istvan and Manolios, Nicholas (2006). Lipidation and glycosylation of a T cell antigen receptor (TCR) transmembrane hvdrophobic peptide dramatically enhances in vitro and in vivo function. Biochimica Et Biophysica Acta-molecular Cell Research, 1763 (8), 879-888. doi: 10.1016/j.bbamcr.2006.04.013 |
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2006 Journal Article Immunization with a tetraepitopic lipid core peptide vaccine construct induces broadly protective immune responses against group A streptococcusOlive, Colleen, Ho, Mei‐Fong, Dyer, Joanne, Lincoln, Douglas, Barozzi, Nadia, Toth, Istvan and Good, Michael F. (2006). Immunization with a tetraepitopic lipid core peptide vaccine construct induces broadly protective immune responses against group A streptococcus. Journal of Infectious Diseases, 193 (12), 1666-1676. doi: 10.1086/504266 |
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2006 Journal Article The lipid core peptide system in vaccine deliveryToth, Istvan, Moyle, Peter, Karpati, Levente, Horvath, Aniko, Olive, Colleen and Good, Michael (2006). The lipid core peptide system in vaccine delivery. International Congress Series, 1289, 307-310. doi: 10.1016/j.ics.2005.11.057 |
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2006 Conference Publication Uptake of a multi-component non-viral gene delivery system and gene expression in mammalian cellsYang, S, Coles, D. J., Esposito, A., Mitchell, D J, Toth, I and Minchin, R F (2006). Uptake of a multi-component non-viral gene delivery system and gene expression in mammalian cells. Annual Conference of the Australasian Pharmaceutical Science n, Adelaide, 3-5 December, 2006. |
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2006 Conference Publication Synthesis and characterisation of Trp modified Leu-Enkephalin analoguesDel Borgo, M, Wang, R., Toth, I and Blanchfield, J T (2006). Synthesis and characterisation of Trp modified Leu-Enkephalin analogues. Brisbane Biological & Organic Chemistry Symposium, Brisbane, 24 Nov 2006. |
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2006 Journal Article Method for the synthesis of highly pure vaccines using the lipid core peptide systemMoyle, P. M., Olive, C., Good, M. F. and Toth, I. (2006). Method for the synthesis of highly pure vaccines using the lipid core peptide system. Journal of Peptide Science, 12 (12), 800-807. doi: 10.1002/psc.815 |
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2006 Journal Article Enhancement of drug affinity for cell membranes by conjugation with lipoamino acids II. Experimental and computational evidence using biomembrane modelsPignatello, Rosario, Guccione, Salvatore, Castelli, Francesco, Sarpietro, Maria G., Giurato, Laura, Lombardo, Massimo, Puglisi, Giovanni and Toth, Istvan (2006). Enhancement of drug affinity for cell membranes by conjugation with lipoamino acids II. Experimental and computational evidence using biomembrane models. International Journal of Pharmaceutics, 310 (1-2), 53-63. doi: 10.1016/j.ijpharm.2005.11.044 |
