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2006

Journal Article

Method for the synthesis of highly pure vaccines using the lipid core peptide system

Moyle, P. M., Olive, C., Good, M. F. and Toth, I. (2006). Method for the synthesis of highly pure vaccines using the lipid core peptide system. Journal of Peptide Science, 12 (12), 800-807. doi: 10.1002/psc.815

Method for the synthesis of highly pure vaccines using the lipid core peptide system

2006

Journal Article

Enhancement of drug affinity for cell membranes by conjugation with lipoamino acids II. Experimental and computational evidence using biomembrane models

Pignatello, Rosario, Guccione, Salvatore, Castelli, Francesco, Sarpietro, Maria G., Giurato, Laura, Lombardo, Massimo, Puglisi, Giovanni and Toth, Istvan (2006). Enhancement of drug affinity for cell membranes by conjugation with lipoamino acids II. Experimental and computational evidence using biomembrane models. International Journal of Pharmaceutics, 310 (1-2), 53-63. doi: 10.1016/j.ijpharm.2005.11.044

Enhancement of drug affinity for cell membranes by conjugation with lipoamino acids II. Experimental and computational evidence using biomembrane models

2006

Conference Publication

Chemoselective peptide attachment to well-defined star polymer for peptide delivery

Liang, M, Monteiro, M J and Toth, I (2006). Chemoselective peptide attachment to well-defined star polymer for peptide delivery. Annual Conference of the Australasian Pharmaceutical Science n, Adelaide, 3-5 Dec, 2006.

Chemoselective peptide attachment to well-defined star polymer for peptide delivery

2006

Conference Publication

Liposaccharide based vaccine carrier adjuvant systems

Simerska, P., Bong, Y. K., McGeary, R. P., Moyle, P. M. and Toth, I. (2006). Liposaccharide based vaccine carrier adjuvant systems. Drug Design Amongst the Vines, Hunter Valley, 3 - 7 December 2006.

Liposaccharide based vaccine carrier adjuvant systems

2006

Conference Publication

Structure-activity relationships of potential self-adjuvanting vaccines against Group A streptococcus based on the carboxyl group of its M-protein

Abdel-Aal, A. M. and Toth, I (2006). Structure-activity relationships of potential self-adjuvanting vaccines against Group A streptococcus based on the carboxyl group of its M-protein. Brisbane Biological & Organic Chemistry Symposium, Brisbane, 24 November 2006.

Structure-activity relationships of potential self-adjuvanting vaccines against Group A streptococcus based on the carboxyl group of its M-protein

2006

Journal Article

Anti-proliferative effects of novel Glyco-lipid-arsenicals (III) on MCF-7 human breast cancer cells

Wimmer, N., Robinson, J. A., Gopisetty Venkata, N., Roberts-Thomson, S. J., Monteith, G. R. and Toth, I. (2006). Anti-proliferative effects of novel Glyco-lipid-arsenicals (III) on MCF-7 human breast cancer cells. Medicinal Chemistry, 2 (1), 79-87. doi: 10.2174/157340606775197714

Anti-proliferative effects of novel Glyco-lipid-arsenicals (III) on MCF-7 human breast cancer cells

2006

Journal Article

Synthesis of a library of polycationic lipid core dendrimers and their evaluation in the delivery of an oligonucleotide with hVEGF inhibition

Parekh, H. S., Marano, R. J., Rakoczy, E. P., Blanchfield, J. and Toth, I. (2006). Synthesis of a library of polycationic lipid core dendrimers and their evaluation in the delivery of an oligonucleotide with hVEGF inhibition. Bioorganic & Medicinal Chemistry, 14 (14), 4775-4780. doi: 10.1016/j.bmc.2006.03.029

Synthesis of a library of polycationic lipid core dendrimers and their evaluation in the delivery of an oligonucleotide with hVEGF inhibition

2005

Journal Article

Dendrimer delivery of an anti-VEGF oligonucleotide into the eye: A long-term study into inhibition of laser-induced CNV, distribution, uptake and toxicity

Marano, R. J., Toth, I., Wimmer, N., Brankov, M. and Rakoczy, E. P. (2005). Dendrimer delivery of an anti-VEGF oligonucleotide into the eye: A long-term study into inhibition of laser-induced CNV, distribution, uptake and toxicity. Gene Therapy, 12 (21), 1544-1550. doi: 10.1038/sj.gt.3302579

Dendrimer delivery of an anti-VEGF oligonucleotide into the eye: A long-term study into inhibition of laser-induced CNV, distribution, uptake and toxicity

2005

Journal Article

Gastrointestinal absorption of Heparin by lipidization or coadministration with penetration enhancers

Ross, B. P. and Toth, I. (2005). Gastrointestinal absorption of Heparin by lipidization or coadministration with penetration enhancers. Current Drug Delivery, 2 (3), 277-287. doi: 10.2174/1567201054367968

Gastrointestinal absorption of Heparin by lipidization or coadministration with penetration enhancers

2005

Conference Publication

Protection against group A streptococcal infection by vaccination with self-adjuvanting lipid core M protein peptides

Olive, C., Hsien, K., Horvath, A., Clair, T., Yarwood, P., Toth, I. and Good, M. F. (2005). Protection against group A streptococcal infection by vaccination with self-adjuvanting lipid core M protein peptides. 4th World Congress on Vaccines and Immunisation (WCVI), Tokyo Japan, Sep 30-Oct 03, 2004. Oxford, U.K.: Elsevier. doi: 10.1016/j.vaccine.2005.01.041

Protection against group A streptococcal infection by vaccination with self-adjuvanting lipid core M protein peptides

2005

Journal Article

Functional implications of modifying RyR‐activating peptides for membrane permeability

Dulhunty, Angela F., Cengia, Louise, Young, Jacqui, Pace, Suzy M., Harvey, Peta J., Lamb, Graham D., Chan, Yiu-Ngok, Wimmer, Norbert, Toth, Istvan and Casarotto, Marco G. (2005). Functional implications of modifying RyR‐activating peptides for membrane permeability. British Journal of Pharmacology, 144 (6), 743-754. doi: 10.1038/sj.bjp.0705981

Functional implications of modifying RyR‐activating peptides for membrane permeability

2005

Conference Publication

The chemoenzymatic synthesis of oligosaccharide-linked peptides aimed at improved drug delivery

Johnstone, K.D., Dieckelmann, M., Jennings, M.P., Blanchfield, J.T. and Toth, I. (2005). The chemoenzymatic synthesis of oligosaccharide-linked peptides aimed at improved drug delivery. 19th American Peptide Symposium, San Diego, CA, United States, 18-23 June 2005. Hoboken, NJ, United States: John Wiley & Sons .

The chemoenzymatic synthesis of oligosaccharide-linked peptides aimed at improved drug delivery

2005

Book Chapter

Modification of peptides and other drugs using lipoamino acids and sugars

Blanchfield, J. T. and Toth, I. (2005). Modification of peptides and other drugs using lipoamino acids and sugars. Methods in Molecular Biology: Peptide Synthesis and Applications. (pp. 45-61) edited by John Howl. New Jersey: Humana Press. doi: 10.1385/1-59259-877-3:045

Modification of peptides and other drugs using lipoamino acids and sugars

2005

Conference Publication

Anti-proliferative effects of novel glyco-lipoaminoacid-modified arsenicals (III) on MCF-7 human breast cancer cells

Wimmer, N., Robinson, J. A., Thomson, S. J., Monteith, G. R. and Toth, I. (2005). Anti-proliferative effects of novel glyco-lipoaminoacid-modified arsenicals (III) on MCF-7 human breast cancer cells. 19th American Peptide Symposium, San Diego, U.S., 18-23 June, 2005. Hoboken, U.S.: Wiley Interscience.

Anti-proliferative effects of novel glyco-lipoaminoacid-modified arsenicals (III) on MCF-7 human breast cancer cells

2005

Journal Article

Encapsulation of lipopeptides within liposomes: Effect of number of lipid chains, chain length and method of liposome preparation

Liang, M. T., Davies, N. M. and Toth, I. (2005). Encapsulation of lipopeptides within liposomes: Effect of number of lipid chains, chain length and method of liposome preparation. International Journal of Pharmaceutics, 301 (1-2), 247-254. doi: 10.1016/j.ijpharm.2005.06.010

Encapsulation of lipopeptides within liposomes: Effect of number of lipid chains, chain length and method of liposome preparation

2005

Conference Publication

A synthetic group A streptococcal vaccine of high purity and broad protective range

Horvath, Aniko, Olive, Colleen, Good, Michael F. and Toth, Istvan (2005). A synthetic group A streptococcal vaccine of high purity and broad protective range. 3rd International Peptide Symposium/28th European Peptide Symposium, Prague Czech Republic, Sep 05-10, 2004. GENEVA 1: KENES INT.

A synthetic group A streptococcal vaccine of high purity and broad protective range

2005

Journal Article

The stability of lipidic analogues of GnRH in plasma and kidney preparations: the stereoselective release of the parent peptide

Blanchfield, J. T., Lew, R. A., Smith, A. I. and Toth, I. (2005). The stability of lipidic analogues of GnRH in plasma and kidney preparations: the stereoselective release of the parent peptide. Bioorganic & Medicinal Chemistry Letters, 15 (6), 1609-1612. doi: 10.1016/j.bmcl.2005.01.069

The stability of lipidic analogues of GnRH in plasma and kidney preparations: the stereoselective release of the parent peptide

2005

Journal Article

Chemo-enzymatic synthesis of a trisaccharide-linked peptide aimed at improved drug-delivery

Johnstone, K. D., Dieckelmann, M., Jennings, M. P., Toth, I. and Blanchfield, J. T. (2005). Chemo-enzymatic synthesis of a trisaccharide-linked peptide aimed at improved drug-delivery. Current Drug Delivery, 2 (3), 215-222. doi: 10.2174/1567201054367977

Chemo-enzymatic synthesis of a trisaccharide-linked peptide aimed at improved drug-delivery

2005

Conference Publication

The synthesis and immunological activity of a lipid-core peptide (LCP) based Human Papillomavirus (HPV) type-16 vaccine

Moyle, Peter M., Olive, Colleen, Sun, Hsien, Good, Michael and Toth, Istvan (2005). The synthesis and immunological activity of a lipid-core peptide (LCP) based Human Papillomavirus (HPV) type-16 vaccine. 3rd International Peptide Symposium and 28th European Peptide Symposium, Prague, Czech Republic, 5-10 September 2004. GENEVA 1: Kenes International.

The synthesis and immunological activity of a lipid-core peptide (LCP) based Human Papillomavirus (HPV) type-16 vaccine

2005

Journal Article

Versatile peptide dendrimers for nucleic acid delivery

Bayele, Henry, Sakthivel, T., O'Donell, Martin, Pasi, K. John, Wilderspin, Andrew F., Lee, Christine A., Toth, Istvan and Florence, Alexander T. (2005). Versatile peptide dendrimers for nucleic acid delivery. Journal of Pharmaceutical Sciences, 94 (2), 446-457. doi: 10.1002/jps.20230

Versatile peptide dendrimers for nucleic acid delivery