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2005

Journal Article

Gastrointestinal absorption of Heparin by lipidization or coadministration with penetration enhancers

Ross, B. P. and Toth, I. (2005). Gastrointestinal absorption of Heparin by lipidization or coadministration with penetration enhancers. Current Drug Delivery, 2 (3), 277-287. doi: 10.2174/1567201054367968

Gastrointestinal absorption of Heparin by lipidization or coadministration with penetration enhancers

2005

Conference Publication

Protection against group A streptococcal infection by vaccination with self-adjuvanting lipid core M protein peptides

Olive, C., Hsien, K., Horvath, A., Clair, T., Yarwood, P., Toth, I. and Good, M. F. (2005). Protection against group A streptococcal infection by vaccination with self-adjuvanting lipid core M protein peptides. 4th World Congress on Vaccines and Immunisation (WCVI), Tokyo Japan, Sep 30-Oct 03, 2004. Oxford, U.K.: Elsevier. doi: 10.1016/j.vaccine.2005.01.041

Protection against group A streptococcal infection by vaccination with self-adjuvanting lipid core M protein peptides

2005

Journal Article

Functional implications of modifying RyR‐activating peptides for membrane permeability

Dulhunty, Angela F., Cengia, Louise, Young, Jacqui, Pace, Suzy M., Harvey, Peta J., Lamb, Graham D., Chan, Yiu-Ngok, Wimmer, Norbert, Toth, Istvan and Casarotto, Marco G. (2005). Functional implications of modifying RyR‐activating peptides for membrane permeability. British Journal of Pharmacology, 144 (6), 743-754. doi: 10.1038/sj.bjp.0705981

Functional implications of modifying RyR‐activating peptides for membrane permeability

2005

Journal Article

Versatile peptide dendrimers for nucleic acid delivery

Bayele, Henry, Sakthivel, T., O'Donell, Martin, Pasi, K. John, Wilderspin, Andrew F., Lee, Christine A., Toth, Istvan and Florence, Alexander T. (2005). Versatile peptide dendrimers for nucleic acid delivery. Journal of Pharmaceutical Sciences, 94 (2), 446-457. doi: 10.1002/jps.20230

Versatile peptide dendrimers for nucleic acid delivery

2005

Book Chapter

Modification of peptides and other drugs using lipoamino acids and sugars

Blanchfield, J. T. and Toth, I. (2005). Modification of peptides and other drugs using lipoamino acids and sugars. Methods in Molecular Biology: Peptide Synthesis and Applications. (pp. 45-61) edited by John Howl. New Jersey: Humana Press. doi: 10.1385/1-59259-877-3:045

Modification of peptides and other drugs using lipoamino acids and sugars

2005

Conference Publication

Anti-proliferative effects of novel glyco-lipoaminoacid-modified arsenicals (III) on MCF-7 human breast cancer cells

Wimmer, N., Robinson, J. A., Thomson, S. J., Monteith, G. R. and Toth, I. (2005). Anti-proliferative effects of novel glyco-lipoaminoacid-modified arsenicals (III) on MCF-7 human breast cancer cells. 19th American Peptide Symposium, San Diego, U.S., 18-23 June, 2005. Hoboken, U.S.: Wiley Interscience.

Anti-proliferative effects of novel glyco-lipoaminoacid-modified arsenicals (III) on MCF-7 human breast cancer cells

2005

Journal Article

Encapsulation of lipopeptides within liposomes: Effect of number of lipid chains, chain length and method of liposome preparation

Liang, M. T., Davies, N. M. and Toth, I. (2005). Encapsulation of lipopeptides within liposomes: Effect of number of lipid chains, chain length and method of liposome preparation. International Journal of Pharmaceutics, 301 (1-2), 247-254. doi: 10.1016/j.ijpharm.2005.06.010

Encapsulation of lipopeptides within liposomes: Effect of number of lipid chains, chain length and method of liposome preparation

2005

Conference Publication

The synthesis and immunological activity of a lipid-core peptide (LCP) based Human Papillomavirus (HPV) type-16 vaccine

Moyle, Peter M., Olive, Colleen, Sun, Hsien, Good, Michael and Toth, Istvan (2005). The synthesis and immunological activity of a lipid-core peptide (LCP) based Human Papillomavirus (HPV) type-16 vaccine. 3rd International Peptide Symposium and 28th European Peptide Symposium, Prague, Czech Republic, 5-10 September 2004. GENEVA 1: Kenes International.

The synthesis and immunological activity of a lipid-core peptide (LCP) based Human Papillomavirus (HPV) type-16 vaccine

2005

Journal Article

The stability of lipidic analogues of GnRH in plasma and kidney preparations: the stereoselective release of the parent peptide

Blanchfield, J. T., Lew, R. A., Smith, A. I. and Toth, I. (2005). The stability of lipidic analogues of GnRH in plasma and kidney preparations: the stereoselective release of the parent peptide. Bioorganic & Medicinal Chemistry Letters, 15 (6), 1609-1612. doi: 10.1016/j.bmcl.2005.01.069

The stability of lipidic analogues of GnRH in plasma and kidney preparations: the stereoselective release of the parent peptide

2005

Conference Publication

The chemoenzymatic synthesis of oligosaccharide-linked peptides aimed at improved drug delivery

Johnstone, K.D., Dieckelmann, M., Jennings, M.P., Blanchfield, J.T. and Toth, I. (2005). The chemoenzymatic synthesis of oligosaccharide-linked peptides aimed at improved drug delivery. 19th American Peptide Symposium, San Diego, CA, United States, 18-23 June 2005. Hoboken, NJ, United States: John Wiley & Sons .

The chemoenzymatic synthesis of oligosaccharide-linked peptides aimed at improved drug delivery

2005

Journal Article

Chemo-enzymatic synthesis of a trisaccharide-linked peptide aimed at improved drug-delivery

Johnstone, K. D., Dieckelmann, M., Jennings, M. P., Toth, I. and Blanchfield, J. T. (2005). Chemo-enzymatic synthesis of a trisaccharide-linked peptide aimed at improved drug-delivery. Current Drug Delivery, 2 (3), 215-222. doi: 10.2174/1567201054367977

Chemo-enzymatic synthesis of a trisaccharide-linked peptide aimed at improved drug-delivery

2005

Conference Publication

A synthetic group A streptococcal vaccine of high purity and broad protective range

Horvath, Aniko, Olive, Colleen, Good, Michael F. and Toth, Istvan (2005). A synthetic group A streptococcal vaccine of high purity and broad protective range. 3rd International Peptide Symposium/28th European Peptide Symposium, Prague Czech Republic, Sep 05-10, 2004. GENEVA 1: KENES INT.

A synthetic group A streptococcal vaccine of high purity and broad protective range

2004

Journal Article

Increased adjuvant activity of minimal CD8 T cell peptides incorporated into lipid-core-peptides

White, K., Kearns, P., Toth, I. and Hook, S. (2004). Increased adjuvant activity of minimal CD8 T cell peptides incorporated into lipid-core-peptides. Immunology And Cell Biology, 82 (5), 517-522. doi: 10.1111/j.1440-1711.2004.01269.x

Increased adjuvant activity of minimal CD8 T cell peptides incorporated into lipid-core-peptides

2004

Journal Article

Inhibition of in vitro VEGF expression and choroidal neovascularization by synthetic dendrimer peptide mediated delivery of a sense oligonucleotide

Marano, Robert J., Wimmer, Norbert, Kearns, Philip S., Thomas, Bradley G., Toth, Istvan, Brankov, Meliha and Rakoczy, P. Elizabeth (2004). Inhibition of in vitro VEGF expression and choroidal neovascularization by synthetic dendrimer peptide mediated delivery of a sense oligonucleotide. Experimental Eye Research, 79 (4), 525-535. doi: 10.1016/j.exer.2004.06.023

Inhibition of in vitro VEGF expression and choroidal neovascularization by synthetic dendrimer peptide mediated delivery of a sense oligonucleotide

2004

Journal Article

Micellar aggregation and membrane partitioning of bile salts, fatty acids, sodium dodecyl sulfate, and sugar-conjugated fatty acids: correlation with hemolytic potency and implications for drug delivery

Ross, Benjamin P., Braddy, April C., McGeary, Ross P., Blanchfield, Joanne T., Prokai, Laszlo and Toth, Istvan (2004). Micellar aggregation and membrane partitioning of bile salts, fatty acids, sodium dodecyl sulfate, and sugar-conjugated fatty acids: correlation with hemolytic potency and implications for drug delivery. Molecular Pharmaceutics, 1 (3), 233-245. doi: 10.1021/mp049964d

Micellar aggregation and membrane partitioning of bile salts, fatty acids, sodium dodecyl sulfate, and sugar-conjugated fatty acids: correlation with hemolytic potency and implications for drug delivery

2004

Conference Publication

Investigation of urotensin-II converting enzyme activity in human cells and blood

Kearns, P., Russell, F. D., Toth, I. and Molenaar, P. (2004). Investigation of urotensin-II converting enzyme activity in human cells and blood. 8th Annual Scientific Sessions of the Latin American Section of the International-Society for Heart Research, Brisbane, Qld, Australia, 7th - 11th August, 2004. United Kingdom: Academic Press. doi: 10.1016/j.yjmcc.2004.05.003

Investigation of urotensin-II converting enzyme activity in human cells and blood

2004

Conference Publication

Liposaccharides in peptide drug delivery

Blanchfield, J. T., Gallagher, O. P., Koda, Y., Alewood, P.F., Lewis, R. J. and Toth, I. (2004). Liposaccharides in peptide drug delivery. 18th American Peptide Symposium, Boston, 19-23 July, 2003. WASHINGTON: AMER CHEMICAL SOC.

Liposaccharides in peptide drug delivery

2004

Journal Article

Group A streptococcal vaccine delivery by immunization with a self-adjuvanting M protein-based lipid core peptide construct

Olive, C., Batzloff, M., Horvath, A., Clair, T., Yarwood, P., Toth, I. and Good, M. F. (2004). Group A streptococcal vaccine delivery by immunization with a self-adjuvanting M protein-based lipid core peptide construct. Indian Journal of Medical Research, 119 (Suppl.), 88-94.

Group A streptococcal vaccine delivery by immunization with a self-adjuvanting M protein-based lipid core peptide construct

2004

Conference Publication

Liposaccharide delivery system: application to conotoxin MII and endomorphin I

Blanchfield, J. T., Koda, Y., Gallagher, O. P. and Toth, I. (2004). Liposaccharide delivery system: application to conotoxin MII and endomorphin I. PSWC 2004, Kyoto, 29 May - 3 June, 2004.

Liposaccharide delivery system: application to conotoxin MII and endomorphin I

2004

Conference Publication

Liposaccharides for drug and vaccine delivery

Toth, I., Horvath, A., Karpati, L., Moyle, P., Olive, C. and Good, M. (2004). Liposaccharides for drug and vaccine delivery. 3rd International and 28th European Peptide Symposium, Prague, Czech Republic, 5–10 September 2004. Chichester, West Sussex, United Kingdom: John Wiley & Sons. doi: 10.1002/psc.618

Liposaccharides for drug and vaccine delivery