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2014

Journal Article

Solution structure, membrane interactions and protein binding partners of the tetraspanin Sm-TSP-2, a vaccine antigen from the human blood fluke Schistosoma mansoni

Jia, Xinying, Schulte, Leigh, Loukas, Alex, Pickering, Darren, Pearson, Mark, Mobli, Mehdi, Jones, Alun, Rosengren, Karl J., Daly, Norelle L., Gobert, Geoffrey N., Jones, Malcolm K., Craik, David J. and Mulvenna, Jason (2014). Solution structure, membrane interactions and protein binding partners of the tetraspanin Sm-TSP-2, a vaccine antigen from the human blood fluke Schistosoma mansoni. Journal of Biological Chemistry, 289 (10), 1-26. doi: 10.1074/jbc.M113.531558

Solution structure, membrane interactions and protein binding partners of the tetraspanin Sm-TSP-2, a vaccine antigen from the human blood fluke Schistosoma mansoni

2014

Journal Article

Semienzymatic cyclization of disulfide-rich peptides using sortase A

Jia, Xinying, Kwon, Soohyun, Wang, Ching-I Anderson, Huang, Yen-Hua, Chan, Lai Y., Tan, Chia Chia, Rosengren, K. Johan, Mulvenna, Jason P., Schroeder, Christina I. and Craik, David J. (2014). Semienzymatic cyclization of disulfide-rich peptides using sortase A. Journal of Biological Chemistry, Papers in Press (10), 1-25. doi: 10.1074/jbc.M113.539262

Semienzymatic cyclization of disulfide-rich peptides using sortase A

2014

Journal Article

Understanding the Molecular Basis of Toxin Promiscuity: The Analgesic Sea Anemone Peptide APETx2 Interacts with Acid-Sensing Ion Channel 3 and hERG Channels via Overlapping Pharmacophores

Jensen, Jonas E., Cristofori-Armstrong, Ben, Anangi, Raveendra, Rosengren, K. Johan, Lau, Carus H. Y., Mobli, Mehdi, Brust, Andreas, Alewood, Paul F., King, Glenn F. and Rash, Lachlan D. (2014). Understanding the Molecular Basis of Toxin Promiscuity: The Analgesic Sea Anemone Peptide APETx2 Interacts with Acid-Sensing Ion Channel 3 and hERG Channels via Overlapping Pharmacophores. Journal of Medicinal Chemistry, 57 (21), 9195-9203. doi: 10.1021/jm501400p

Understanding the Molecular Basis of Toxin Promiscuity: The Analgesic Sea Anemone Peptide APETx2 Interacts with Acid-Sensing Ion Channel 3 and hERG Channels via Overlapping Pharmacophores

2014

Journal Article

Seed storage albumins: Biosynthesis, trafficking and structures

Mylne, Joshua S., Hara-Nishimura, Ikuko and Rosengren, K. Johan (2014). Seed storage albumins: Biosynthesis, trafficking and structures. Functional Plant Biology, 41 (7), 671-677. doi: 10.1071/FP14035

Seed storage albumins: Biosynthesis, trafficking and structures

2013

Journal Article

The Self-Association of the Cyclotide Kalata B2 in Solution is Guided by Hydrophobic Interactions (vol 100, pg 453, 2013)

Rosengren, K. Johan, Daly, Norelle L., Harvey, Peta J. and Craik, David J. (2013). The Self-Association of the Cyclotide Kalata B2 in Solution is Guided by Hydrophobic Interactions (vol 100, pg 453, 2013). Biopolymers, 102 (1), 136-136. doi: 10.1002/bip.22443

The Self-Association of the Cyclotide Kalata B2 in Solution is Guided by Hydrophobic Interactions (vol 100, pg 453, 2013)

2013

Journal Article

Relaxin-3/RXFP3 system regulates alcohol-seeking

Ryan,Philip J., Kastman, Hanna E., Krstew, Elena V., Rosengren, K. Johan, Hossain, Mohammed Akhter, Churilov, Leonid, Wade, John D., Gundlach, Andrew L. and Lawrence, Andrew J. (2013). Relaxin-3/RXFP3 system regulates alcohol-seeking. Proceedings of the National Academy of Sciences of the United States of America, 110 (51), 20789-20794. doi: 10.1073/pnas.1317807110

Relaxin-3/RXFP3 system regulates alcohol-seeking

2013

Journal Article

Structural insights into the role of the cyclic backbone in a squash trypsin inhibitor

Daly, Norelle L., Thorstholm, Louise, Greenwood, Kathryn P., King, Gordon J., Rosengren, K. Johan, Heras, Begona, Martin, Jennifer L. and Craik, David J. (2013). Structural insights into the role of the cyclic backbone in a squash trypsin inhibitor. Journal of Biological Chemistry, 288 (50), 36141-36148. doi: 10.1074/jbc.M113.528240

Structural insights into the role of the cyclic backbone in a squash trypsin inhibitor

2013

Journal Article

The self-association of the cyclotide kalata B2 in solution is guided by hydrophobic interactions

Rosengren, K. Johan, Daly, Norelle L., Harvey, Peta J. and Craik, David J. (2013). The self-association of the cyclotide kalata B2 in solution is guided by hydrophobic interactions. Peptide Science, Accepted Article (5), 1-16. doi: 10.1002/bip.22269

The self-association of the cyclotide kalata B2 in solution is guided by hydrophobic interactions

2013

Journal Article

The cyclic cystine ladder in theta-defensins is important for structure and stability, but not antibacterial activity

Conibear, Anne C., Rosengren, K. Johan, Daly, Norelle L., Henriques, Sonia Troeira and Craik, David J. (2013). The cyclic cystine ladder in theta-defensins is important for structure and stability, but not antibacterial activity. Journal of Biological Chemistry, 288 (15), 10830-10840. doi: 10.1074/jbc.M113.451047

The cyclic cystine ladder in theta-defensins is important for structure and stability, but not antibacterial activity

2013

Journal Article

Conopeptide p-tia defines a new allosteric site on the extracellular surface of the α1b-adrenoceptor

Ragnarsson, Lotten, Wang, Ching-I Anderson, Andersson, Asa, Fajarningsih, Dewi, Monks, Thea, Brust, Andreas, Rosengren, K. Johan and Lewis, Richard J. (2013). Conopeptide p-tia defines a new allosteric site on the extracellular surface of the α1b-adrenoceptor. Journal of Biological Chemistry, 288 (3), 1814-1827. doi: 10.1074/jbc.M112.430785

Conopeptide p-tia defines a new allosteric site on the extracellular surface of the α1b-adrenoceptor

2013

Journal Article

Elucidation of relaxin-3 binding interactions in the extracellular loops of RXFP3

Bathgate, Ross A. D., Oh, Maria H. Y., Ling, W. J. Jason, Kaas, Quentin, Hossain, M. Akhter, Gooley, Paul R. and Rosengren, K. Johan (2013). Elucidation of relaxin-3 binding interactions in the extracellular loops of RXFP3. Frontiers in Endocrinology, 4 (FEB) article 13. doi: 10.3389/fendo.2013.00013

Elucidation of relaxin-3 binding interactions in the extracellular loops of RXFP3

2012

Journal Article

Structural characterization of the cyclic cystine ladder motif of θ-defensins

Conibear, Anne C., Rosengren, K. Johan, Harvey, Peta J. and Craik, David J. (2012). Structural characterization of the cyclic cystine ladder motif of θ-defensins. Biochemistry, 51 (48), 9718-9726. doi: 10.1021/bi301363a

Structural characterization of the cyclic cystine ladder motif of θ-defensins

2012

Journal Article

The different ligand-binding modes of relaxin family peptide receptors RXFP1 and RXFP2

Scott, Daniel J., Rosengren, K. Johan and Bathgate, Ross A. D. (2012). The different ligand-binding modes of relaxin family peptide receptors RXFP1 and RXFP2. Molecular Endocrinology, 26 (11), 1896-1906. doi: 10.1210/me.2012-1188

The different ligand-binding modes of relaxin family peptide receptors RXFP1 and RXFP2

2012

Journal Article

Identification of key residues essential for the structural fold and receptor selectivity within the A-chain of human gene-2 (H2) relaxin

Chan, Linda J., Rosengren, K. Johan, Layfield, Sharon L., Bathgate, Ross A. D., Separovic, Frances, Samuel, Chrishan S., Hossain, Mohammed A. and Wade, John D. (2012). Identification of key residues essential for the structural fold and receptor selectivity within the A-chain of human gene-2 (H2) relaxin. Journal of Biological Chemistry, 287 (49), 41152-41164. doi: 10.1074/jbc.M112.409284

Identification of key residues essential for the structural fold and receptor selectivity within the A-chain of human gene-2 (H2) relaxin

2012

Journal Article

Circular proteins from plants and fungi

Goransson, Ulf, Burman, Robert, Gunasekera, Sunithi, Stromstedt, Adam A. and Rosengren, K. Johan (2012). Circular proteins from plants and fungi. Journal of Biological Chemistry, 287 (32), 27001-27006. doi: 10.1074/jbc.R111.300129

Circular proteins from plants and fungi

2012

Journal Article

Extensive polymorphism in the porcine Toll-like receptor 10 gene

Bergman, I.-M., Edman, K., Ekdahl, K. N., Rosengren, K. J. and Edfors, I. (2012). Extensive polymorphism in the porcine Toll-like receptor 10 gene. International Journal of Immunogenetics, 39 (1), 68-76. doi: 10.1111/j.1744-313X.2011.01057.x

Extensive polymorphism in the porcine Toll-like receptor 10 gene

2012

Journal Article

The structural determinants of insulin-like peptide 3 activity

Bathgate, Ross A. D., Zhang, Soude, Hughes, Richard A., Rosengren, K. Johan and Wade, John D. (2012). The structural determinants of insulin-like peptide 3 activity. Frontiers in Endocrinology, 3 (FEB) Article 11, 11.1-11.10. doi: 10.3389/fendo.2012.00011

The structural determinants of insulin-like peptide 3 activity

2012

Journal Article

The α-defensin salt-bridge induces backbone stability to facilitate folding and confer proteolytic resistance

Andersson, Hakan S., Figueredo, Sharel M., Haugaard-Kedstrom, Linda M., Bengtsson, Elina, Daly, Norelle L., Qu, Xiaoqing, Craik, David J., Ouellette, Andre J. and Rosengren, K. Johan (2012). The α-defensin salt-bridge induces backbone stability to facilitate folding and confer proteolytic resistance. Amino Acids, 43 (4), 1471-1483. doi: 10.1007/s00726-012-1220-3

The α-defensin salt-bridge induces backbone stability to facilitate folding and confer proteolytic resistance

2011

Journal Article

The minimal active structure of human relaxin-2

Hossain, Mohammed Akhter, Rosengren, K. Johan, Samuel, Chrishan S., Shabanpoor, Fazel, Chan, Linda J., Bathgate, Ross A. D. and Wade, John D. (2011). The minimal active structure of human relaxin-2. Journal of Biological Chemistry, 286 (43), 37555-37565. doi: 10.1074/jbc.M111.282194

The minimal active structure of human relaxin-2

2011

Journal Article

Decoding the membrane activity of the cyclotide kalata B1: The importance of phosphatidylethanolamine phospholipids and lipid organization on hemolytic and anti-HIV activities

Henriques, Sónia Troeira, Huang, Yen-Hua, Rosengren, K. Johan, Franquelim, Henri G., Carvalho, Filomena A., Johnson, Adam, Sonza, Secondo, Tachedjian, Gilda, Castanho, Miguel A. R. B., Daly, Norelle L. and Craik, David J. (2011). Decoding the membrane activity of the cyclotide kalata B1: The importance of phosphatidylethanolamine phospholipids and lipid organization on hemolytic and anti-HIV activities. Journal of Biological Chemistry, 286 (27), 24231-24241. doi: 10.1074/jbc.M111.253393

Decoding the membrane activity of the cyclotide kalata B1: The importance of phosphatidylethanolamine phospholipids and lipid organization on hemolytic and anti-HIV activities