|
2021 Journal Article Preclinical Evaluation of a Fluorescent Probe Targeting Receptor CDCP1 for Identification of Ovarian CancerHe, Yaowu, Khan, Tashbib, Kryza, Thomas, Jones, Martina L., Goh, Justin B., Lyons, Nicholas J., Pearce, Lesley A., Lee, Michael D, Gough, Madeline, Rogers, Rebecca, Davies, Claire M,, Gilks, C. Blake, Hodgkinson, Thomas, Lourie, Rohan, Barry, Sinead C., Perrin, Lewis C., Williams, Charlotte C., Puttick, Simon, Adams, Timothy E., Munro, Trent P., Hooper, John D. and Chetty, Naven (2021). Preclinical Evaluation of a Fluorescent Probe Targeting Receptor CDCP1 for Identification of Ovarian Cancer. Molecular Pharmaceutics, 18 (9) acs.molpharmaceut.1c00401, 3464-3474. doi: 10.1021/acs.molpharmaceut.1c00401 |
|
2021 Journal Article Extracellular vesicle transmission of chemoresistance to ovarian cancer cells is associated with hypoxia-induced expression of glycolytic pathway proteins, and prediction of epithelial ovarian cancer disease recurrenceAlharbi, Mona, Lai, Andrew, Sharma, Shayna, Kalita-De Croft, Priyakshi, Godbole, Nihar, Campos, America, Guanzon, Dominic, Salas-Burgos, Alexis, Carrion, Flavio, Zuñiga, Felipe A., Perrin, Lewis, He, Yaowu, Pejovic, Tanja, Winters, Carmen, Morgan, Terry, Hooper, John D., Rice, Gregory E. and Salomon, Carlos (2021). Extracellular vesicle transmission of chemoresistance to ovarian cancer cells is associated with hypoxia-induced expression of glycolytic pathway proteins, and prediction of epithelial ovarian cancer disease recurrence. Cancers, 13 (14) 3388, 1-26. doi: 10.3390/cancers13143388 |
|
2021 Journal Article Substrate-biased activity-based probes identify proteases that cleave receptor CDCP1Kryza, Thomas, Khan, Tashbib, Lovell, Scott, Harrington, Brittney S., Yin, Julia, Porazinski, Sean, Pajic, Marina, Koistinen, Hannu, Rantala, Juha K., Dreyer, Tobias, Magdolen, Viktor, Reuning, Ute, He, Yaowu, Tate, Edward W. and Hooper, John D. (2021). Substrate-biased activity-based probes identify proteases that cleave receptor CDCP1. Nature Chemical Biology, 17 (7), 776-783. doi: 10.1038/s41589-021-00783-w |
|
2021 Journal Article The CDCP1 signalling hub: a target for cancer detection and therapeutic interventionKhan, Tashbib, Kryza, Thomas, Lyons, Nicholas J., He, Yaowu and Hooper, John D. (2021). The CDCP1 signalling hub: a target for cancer detection and therapeutic intervention. Cancer Research, 81 (9) canres.2978.2020, QF1-QF11. doi: 10.1158/0008-5472.can-20-2978 |
|
2021 Journal Article Histone modifying enzymes in gynaecological cancersRamarao-Milne, Priya, Kondrashova, Olga, Barry, Sinead, Hooper, John D., Lee, Jason S. and Waddell, Nicola (2021). Histone modifying enzymes in gynaecological cancers. Cancers, 13 (4) 816, 1-21. doi: 10.3390/cancers13040816 |
|
2021 Journal Article A nucleotide analog prevents colitis associated cancer via Β-catenin independently of inflammation and autophagySheng, Yong Hua, Giri, Rabina, Davies, Julie, Schreiber, Veronika, Alabbas, Saleh, Movva, Ramya, He, Yaowu, Wu, Andy, Hooper, John, McWhinney, Brett, Oancea, Iulia, Kijanka, Gregor, Hasnain, Sumaira, Lucke, Andrew J., Fairlie, David P., McGuckin, Michael A., Florin, Timothy H. and Begun, Jakob (2021). A nucleotide analog prevents colitis associated cancer via Β-catenin independently of inflammation and autophagy. Cellular and Molecular Gastroenterology and Hepatology, 11 (1), 33-53. doi: 10.1016/j.jcmgh.2020.05.012 |
|
2020 Journal Article PET imaging quantifying Ga-PSMA-11 uptake in metastatic colorectal cancerCuda, Tahleesa J., Riddell, Andrew D., Liu, Cheng, Whitehall, Vicki L., Borowsky, Jennifer, Wyld, David K., Burge, Matthew E., Ahern, Elizabeth, Griffin, Alison, Lyons, Nicholas J. R., Rose, Stephen E., Clark, David A., Stevenson, Andrew R. L., Hooper, John D., Puttick, Simon and Thomas, Paul A. (2020). PET imaging quantifying Ga-PSMA-11 uptake in metastatic colorectal cancer. The Journal of Nuclear Medicine, 61 (11), 1576-1579. doi: 10.2967/jnumed.119.233312 |
|
2020 Journal Article Revisiting Glycogen in Cancer: A Conspicuous and Targetable Enabler of Malignant TransformationKhan, Tashbib, Sullivan, Mitchell A., Gunter, Jennifer H., Kryza, Thomas, Lyons, Nicholas, He, Yaowu and Hooper, John D. (2020). Revisiting Glycogen in Cancer: A Conspicuous and Targetable Enabler of Malignant Transformation. Frontiers in Oncology, 10 592455, 592455. doi: 10.3389/fonc.2020.592455 |
|
2020 Journal Article HBV induced hepatocellular carcinoma and related potential immunotherapyJia, Liyang, Gao, Yanan, He, Yaowu, Hooper, John D. and Yang, Pengyuan (2020). HBV induced hepatocellular carcinoma and related potential immunotherapy. Pharmacological Research, 159 104992, 104992. doi: 10.1016/j.phrs.2020.104992 |
|
2020 Journal Article miRNa signature in small extracellular vesicles and their association with platinum resistance and cancer recurrence in ovarian cancerAlharbi, Mona, Sharma, Shayna, Guanzon, Dominic, Lai, Andrew, Zuñiga, Felipe, Shiddiky, Muhammad J.A., Yamauchi, Yusuke, Salas-Burgos, Alexis, He, Yaowu, Pejovic, Tanja, Winters, Carmen, Morgan, Terry, Perrin, Lewis, Hooper, John D. and Salomon, Carlos (2020). miRNa signature in small extracellular vesicles and their association with platinum resistance and cancer recurrence in ovarian cancer. Nanomedicine: Nanotechnology, Biology, and Medicine, 28 102207, 102207. doi: 10.1016/j.nano.2020.102207 |
|
2020 Journal Article Risk-targeted alternatives to deterministic ground motion caps in US seismic provisionsStewart, Jonathan P., Luco, Nicolas, Hooper, John D. and Crouse, C. B. (2020). Risk-targeted alternatives to deterministic ground motion caps in US seismic provisions. Earthquake Spectra, 36 (2), 904-923. doi: 10.1177/8755293019892010 |
|
2020 Journal Article Disruption of glycogen utilization markedly improves the efficacy of carboplatin against preclinical models of clear cell ovarian carcinomaKhan, Tashbib, He, Yaowu, Kryza, Thomas, Harrington, Brittney S., Gunter, Jennifer H., Sullivan, Mitchell A., Cuda, Tahleesa, Rogers, Rebecca, Davies, Claire M., Broomfield, Amy, Gough, Madeline, Wu, Andy C., McGann, Thomas, Weroha, S. John, Haluska, Paul, Forbes, Josephine M., Armes, Jane E., Barry, Sinead C., Coward, Jermaine I., Jagasia, Nisha, Chetty, Naven, Snell, Cameron E., Lourie, Rohan, Perrin, Lewis C. and Hooper, John D. (2020). Disruption of glycogen utilization markedly improves the efficacy of carboplatin against preclinical models of clear cell ovarian carcinoma. Cancers, 12 (4) 869, 869. doi: 10.3390/cancers12040869 |
|
2020 Journal Article Anti-CDCP1 immuno-conjugates for detection and inhibition of ovarian cancerHarrington, Brittney S., He, Yaowu, Khan, Tashbib, Puttick, Simon, Conroy, Paul J., Kryza, Thomas, Cuda, Tahleesa, Sokolowski, Kamil A., Tse, Brian W.C ., Robbins, Katherine K., Arachchige, Buddhika J., Stehbens, Samantha J., Pollock, Pamela M., Reed, Sarah, Weroha, S. John, Haluska, Paul, Salomon, Carlos, Lourie, Rohan, Perrin, Lewis C., Law, Ruby H. P., Whisstock, James C. and Hooper, John D. (2020). Anti-CDCP1 immuno-conjugates for detection and inhibition of ovarian cancer. Theranostics, 10 (5), 2095-2114. doi: 10.7150/thno.30736 |
|
2020 Journal Article Effective targeting of intact and proteolysed CDCP1 for imaging and treatment of pancreatic ductal adenocarcinomaKryza, Thomas, Khan, Tashbib, Puttick, Simon, Li, Chao, Sokolowski, Kamil A., Tse, Brian W.C., Cuda, Tahleesa, Lyons, Nicholas, Gough, Madeline, Yin, Julia, Parkin, Ashleigh, Deryugina, Elena I., Quigley, James P., Law, Ruby H.P., Whisstock, James C., Riddell, Andrew D., Barbour, Andrew P., Wyld, David K., Thomas, Paul A., Rose, Stephen, Snell, Cameron E., Pajic, Marina, He, Yaowu and Hooper, John D. (2020). Effective targeting of intact and proteolysed CDCP1 for imaging and treatment of pancreatic ductal adenocarcinoma. Theranostics, 10 (9), 4116-4133. doi: 10.7150/thno.43589 |
|
2019 Journal Article The molecular function of kallikrein-related peptidase 14 demonstrates a key modulatory role in advanced prostate cancerKryza, Thomas, Bock, Nathalie, Lovell, Scott, Rockstroh, Anja, Lehman, Melanie L., Lesner, Adam, Panchadsaram, Janaththani, Silva, Lakmali Munasinghage, Srinivasan, Srilakshmi, Snell, Cameron E., Williams, Elizabeth D., Fazli, Ladan, Gleave, Martin, Batra, Jyotsna, Nelson, Colleen, Tate, Edward W., Harris, Jonathan, Hooper, John D. and Clements, Judith A. (2019). The molecular function of kallikrein-related peptidase 14 demonstrates a key modulatory role in advanced prostate cancer. Molecular Oncology, 14 (1) 1878-0261.12587, 105-128. doi: 10.1002/1878-0261.12587 |
|
2019 Journal Article CDCP1 enhances Wnt signaling in colorectal cancer promoting nuclear localization of β-catenin and E-cadherinHe, Yaowu, Davies, Claire M., Harrington, Brittney S., Hellmers, Linh, Sheng, Yonghua, Broomfield, Amy, McGann, Thomas, Bastick, Kate, Zhong, Laurie, Wu, Andy, Maresh, Grace, McChesney, Shannon, Yau Wong, Kuan, Adams, Mark N., Sullivan, Ryan C., Palmer, James S., Burke, Lez J., Ewing, Adam D., Zhang, Xin, Margolin, David, Li, Li, Lourie, Rohan, Matsika, Admire, Srinivasan, Bhuvana, McGuckin, Michael A., Lumley, John W. and Hooper, John D. (2019). CDCP1 enhances Wnt signaling in colorectal cancer promoting nuclear localization of β-catenin and E-cadherin. Oncogene, 39 (1), 219-233. doi: 10.1038/s41388-019-0983-3 |
|
2019 Journal Article MUC13 promotes the development of colitis-associated colorectal tumors via β-catenin activitySheng, Yong Hua, Wong, Kuan Yau, Seim, Inge, Wang, Ran, He, Yaowu, Wu, Andy, Patrick, Maya, Lourie, Rohan, Schreiber, Veronika, Giri, Rabina, Ng, Choa Ping, Popat, Amirali, Hooper, John, Kijanka, Gregor, Florin, Timothy H., Begun, Jakob, Radford, Kristen J., Hasnain, Sumaira and McGuckin, Michael A. (2019). MUC13 promotes the development of colitis-associated colorectal tumors via β-catenin activity. Oncogene, 38 (48), 7294-7310. doi: 10.1038/s41388-019-0951-y |
|
2019 Journal Article Ovarian cancer-derived exosomes promote tumor metastasis in vivo an effect modulated by the invasiveness capacity of their originating cellsAlharbi, Mona, Lai, Andrew, Guanzon, Dominic, Palma, Carlos, Zuñiga, Felipe, Perrin, Lewis, He, Yaowu, Hooper, John D and Salomon, Carlos (2019). Ovarian cancer-derived exosomes promote tumor metastasis in vivo an effect modulated by the invasiveness capacity of their originating cells. Clinical Science, 133 (13), CS20190082-1419. doi: 10.1042/cs20190082 |
|
2018 Journal Article The potential role of miRNAs and exosomes in chemotherapy in ovarian cancerAlharbi, Mona, Zuñiga, Felipe, Elfeky, Omar, Guanzon, Dominic, Lai, Andrew, Rice, Gregory E., Perrin, Lewis, Hooper, John and Salomon, Carlos (2018). The potential role of miRNAs and exosomes in chemotherapy in ovarian cancer. Endocrine-Related Cancer, 25 (12), R663-R685. doi: 10.1530/erc-18-0019 |
|
2018 Journal Article Proteomic analysis of exosomes reveals an association between cell invasiveness and exosomal bioactivity on endothelial and mesenchymal cell migrationSharma, Shayna, Alharbi, Mona, Kobayashi, Miharu, Lai, Andrew, Guanzon, Dominic, Zuñiga, Felipe, Ormazabal, Valeska, Palma, Carlos, Scholz-Romero, Katherin, Rice, Gregory E., Hooper, John D. and Salomon, Carlos (2018). Proteomic analysis of exosomes reveals an association between cell invasiveness and exosomal bioactivity on endothelial and mesenchymal cell migration. Clinical Science, 132 (18), 2029-2044. doi: 10.1042/CS20180425 |
