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2016

Journal Article

CRIg-expressing peritoneal macrophages are associated with disease severity in patients with cirrhosis and ascites

Irvine, Katharine M., Xuan Banh, Gadd, Victoria L., Wojcik, Kyle K., Ariffin, Juliana K., Jose, Sara, Lukowski, Samuel, Baillie, Gregory J., Sweet, Matthew J. and Powell, Elizabeth E. (2016). CRIg-expressing peritoneal macrophages are associated with disease severity in patients with cirrhosis and ascites. JCI Insight, 1 (8) e86914, e86914. doi: 10.1172/jci.insight.86914

CRIg-expressing peritoneal macrophages are associated with disease severity in patients with cirrhosis and ascites

2016

Journal Article

Patterns of service utilisation within Australian hepatology clinics: high prevalence of advanced liver disease

El-Atem, N. A., Wojcik, K., Horsfall, L., Irvine, K. M., Johnson, T., McPhail, S. M. and Powell, E. E. (2016). Patterns of service utilisation within Australian hepatology clinics: high prevalence of advanced liver disease. Internal Medicine Journal, 46 (4), 420-426. doi: 10.1111/imj.13008

Patterns of service utilisation within Australian hepatology clinics: high prevalence of advanced liver disease

2016

Journal Article

Spatiotemporal characterization of the cellular and molecular contributors to liver fibrosis in a murine hepatotoxic-injury model

Melino, Michelle, Gadd, Victoria L., Alexander, Kylie A., Beattie, Lynette, Lineburg, Katie E., Martinez, Michelle, Teal, Bianca, Le Texier, Laetitia, Irvine, Katharine M., Miller, Gregory C., Boyle, Glen M., Hill, Geoffrey R., Clouston, Andrew D., Powel, Elizabeth E. and MacDonald, Kelli P. A. (2016). Spatiotemporal characterization of the cellular and molecular contributors to liver fibrosis in a murine hepatotoxic-injury model. American Journal of Pathology, 186 (3), 524-538. doi: 10.1016/j.ajpath.2015.10.029

Spatiotemporal characterization of the cellular and molecular contributors to liver fibrosis in a murine hepatotoxic-injury model

2016

Journal Article

Salmonella employs multiple mechanisms to subvert the TLR-inducible zinc-mediated antimicrobial response of human macrophages

Kapetanovic, Ronan, Bokil, Nilesh J., Achard, Maud E. S., Ong, Cheryl-lynn Y, Peters, Kate M., Stocks, Claudia J., Phan, Minh-Duy, Monteleone, Mercedes, Schroder, Kate, Irvine, Katharine M., Saunders, Bernadette M., Walker, Mark J., Stacey, Katryn J., McEwan, Alastair G., Schembri, Mark A. and Sweet, Matthew J. (2016). Salmonella employs multiple mechanisms to subvert the TLR-inducible zinc-mediated antimicrobial response of human macrophages. The FASEB Journal, 30 (5), 1901-1912. doi: 10.1096/fj.201500061

Salmonella employs multiple mechanisms to subvert the TLR-inducible zinc-mediated antimicrobial response of human macrophages

2016

Conference Publication

Non-invasive markers indicate a high prevalence of advanced fibrosis in adults with type 2 diabetes

Patel, P. J., Stuart, K. A., Horsfall, L. U., Hossain, F., Williams, S., Johnson, T., Brown, N., Lampe, G., Buck, L., Clouston, A., Irvine, K. M., Russell, A. and Powell, E. E. (2016). Non-invasive markers indicate a high prevalence of advanced fibrosis in adults with type 2 diabetes. Gastroenterological Society of Australia, Australian Gastroenterology Week 2016, Adelaide, South Australia, Australia, 10–12 October, 2016. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.13520

Non-invasive markers indicate a high prevalence of advanced fibrosis in adults with type 2 diabetes

2016

Conference Publication

Medication adherence in outpatients with decompensated cirrhosis

Hayward, K. L., Cottrell, W. N., Karmakar, A., Patel, P. J., Horsfall, L. U., Martin, J. H., Irvine, K. M., Tallis, C. J., Wright, P. L., Stuart, K. A., Valery, P. C. and Powell, E. E. (2016). Medication adherence in outpatients with decompensated cirrhosis. Gastroenterological Society of Australia, Australian Gastroenterology Week 2016, Adelaide, SA Australia, 10–12 October 2016. Richmond, VIC Australia: Wiley-Blackwell. doi: 10.1111/jgh.13520

Medication adherence in outpatients with decompensated cirrhosis

2015

Journal Article

Can paracetamol (acetaminophen) be administered to patients with liver impairment?

Hayward, Kelly L., Powell, Elizabeth E., Irvine, Katharine M. and Martin, Jennifer H. (2015). Can paracetamol (acetaminophen) be administered to patients with liver impairment?. British Journal of Clinical Pharmacology, 81 (2), 210-222. doi: 10.1111/bcp.12802

Can paracetamol (acetaminophen) be administered to patients with liver impairment?

2015

Journal Article

Deletion of Wntless in myeloid cells exacerbates liver fibrosis and the ductular reaction in chronic liver injury

Irvine, Katharine M., Clouston, Andrew D., Gadd, Victoria L., Miller, Gregory C., Wong, Weng-Yew, Melino, Michelle, Maradana, Muralidhara Rao, MacDonald, Kelli, Lang, Richard A., Sweet, Matthew J., Blumenthal, Antje and Powell, Elizabeth E. (2015). Deletion of Wntless in myeloid cells exacerbates liver fibrosis and the ductular reaction in chronic liver injury. Fibrogenesis and Tissue Repair, 8 (19) 19, 19. doi: 10.1186/s13069-015-0036-7

Deletion of Wntless in myeloid cells exacerbates liver fibrosis and the ductular reaction in chronic liver injury

2015

Journal Article

The Enhanced liver fibrosis score is associated with clinical outcomes and disease progression in patients with chronic liver disease

Irvine, Katharine M., Wockner, Leesa F., Shanker, Mihir, Fagan, Kevin J., Horsfall, Leigh U., Fletcher, Linda M., Ungerer, Jacobus P. J., Pretorius, Carel J., Miller, Gregory C., Clouston, Andrew D., Lampe, Guy and Powell, Elizabeth E. (2015). The Enhanced liver fibrosis score is associated with clinical outcomes and disease progression in patients with chronic liver disease. Liver International, 36 (3), 370-377. doi: 10.1111/liv.12896

The Enhanced liver fibrosis score is associated with clinical outcomes and disease progression in patients with chronic liver disease

2015

Journal Article

Expression profiling pre-diabetic mice to uncover drugs with clinical application to type 1 diabetes

Pang, Dimeng, Irvine, Katharine M., Mehdi, Ahmed M., Thomas, Helen E., Harris, Mark, Hamilton-Williams, Emma E. and Thomas, Ranjeny (2015). Expression profiling pre-diabetic mice to uncover drugs with clinical application to type 1 diabetes. Clinical and Translational Immunology, 4 (8) e41, e41.1-e41.9. doi: 10.1038/cti.2015.17

Expression profiling pre-diabetic mice to uncover drugs with clinical application to type 1 diabetes

2015

Journal Article

Response to ELF cut-off points: aetiology is also a relevant factor

Powell, Elizabeth E., Irvine, Katharine M., Fagan, Kevin J., Ballard, Emma and O'Rourke, Peter (2015). Response to ELF cut-off points: aetiology is also a relevant factor. Liver International, 35 (7), 1921-1921. doi: 10.1111/liv.12822

Response to ELF cut-off points: aetiology is also a relevant factor

2015

Journal Article

ELF score ≥9.8 indicates advanced hepatic fibrosis and is influenced by age, steatosis and histological activity

Fagan, Kevin J., Pretorius, Carel J., Horsfall, Leigh U., Irvine, Katharine M., Wilgen, Urs, Choi, Kihoon, Fletcher, Linda M., Tate, Jill, Melino, Michelle, Nusrat, Sharmin, Miller, Gregory C., Clouston, Andrew D., Ballard, Emma, O'Rourke, Peter, Lampe, Guy, Ungerer, Jacobus P. J. and Powell, Elizabeth E. (2015). ELF score ≥9.8 indicates advanced hepatic fibrosis and is influenced by age, steatosis and histological activity. Liver International, 35 (6), 1673-1681. doi: 10.1111/liv.12760

ELF score ≥9.8 indicates advanced hepatic fibrosis and is influenced by age, steatosis and histological activity

2015

Journal Article

Ascites bacterial burden and immune cell profile are associated with poor clinical outcomes in the absence of overt infection

Fagan, Kevin J., Rogers, Geraint B., Melino, Michelle, Arthur, Dionne M., Costello, Mary-Ellen, Morrison, Mark, Powell, Elizabeth E. and Irvine, Katharine M. (2015). Ascites bacterial burden and immune cell profile are associated with poor clinical outcomes in the absence of overt infection. PLoS One, 10 (3) e0120642, e0120642. doi: 10.1371/journal.pone.0120642

Ascites bacterial burden and immune cell profile are associated with poor clinical outcomes in the absence of overt infection

2015

Conference Publication

Discrepancies in the use of medications in patients with cirrhosis

Hayward, K., Valery, P. C., Cottrell, N., Irvine, K., Horsfall, L., Ruffin, B., Tallis, C., Chachay, V., Martin, J. and Powell, E. (2015). Discrepancies in the use of medications in patients with cirrhosis. GESA-AGW and WGO International Congress, Gastroenterological Society of Australia Australian Gastroenterology Week, Brisbane, QLD Australia, 28 September - 2 October 2015. Richmond, VIC Australia: Wiley-Blackwell. doi: 10.1111/jgh.13093

Discrepancies in the use of medications in patients with cirrhosis

2015

Conference Publication

Economic consideration for reducing hospital presentations among patients with decompensated cirrhosis: not all presentations avoided can be considered equal

Mcphail, S. M., Horsfall, L., Irvine, K., Fagan, K. J. and Powell, E. E. (2015). Economic consideration for reducing hospital presentations among patients with decompensated cirrhosis: not all presentations avoided can be considered equal. Gastro 2015 GESA-AGW and WGO International Congress, Gastroenterological Society of Australia Australian Gastroenterology Week 2015 World Congress of Gastroenterology, Brisbane, Queensland, Australia, 28 September-2 October 2015. Richmond, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.13093

Economic consideration for reducing hospital presentations among patients with decompensated cirrhosis: not all presentations avoided can be considered equal

2015

Conference Publication

Predicting clinical outcomes in chronic liver disease: the ELF test is superior to histology and simple scores

Irvine, K. M., Wockner, L. F., Shanker, M., Fagan, K. J., Horsfall, L. U., Fletcher, L. M., Ungerer, J., Pretorius, C. J., Miller, G. C., Clouston, A. D., Lampe, G. and Powell, E. E. (2015). Predicting clinical outcomes in chronic liver disease: the ELF test is superior to histology and simple scores. Gastro 2015 GESA-AGW and WGO International Congress, Gastroenterological Society of Australia Australian Gastroenterology Week 2015 | World Congress of Gastroenterology, Brisbane, QLD, Australia, 28 September-2 October 2015. Richmond, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.13093

Predicting clinical outcomes in chronic liver disease: the ELF test is superior to histology and simple scores

2015

Conference Publication

Deletion of Wntless in macrophages exacerbates liver fibrosis and the ductular reaction in chronic liver injury

Irvine, Katharine, Clouston, Andrew D., Blumenthal, Antje and Powell, Elizabeth E. (2015). Deletion of Wntless in macrophages exacerbates liver fibrosis and the ductular reaction in chronic liver injury. 66th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD), San Francisco, United States, Nov 13-17, 2015. Hoboken, United States: John Wiley & Sons.

Deletion of Wntless in macrophages exacerbates liver fibrosis and the ductular reaction in chronic liver injury

2015

Conference Publication

Blocking Wnt protein secretion from macrophages exacerbates liver fibrosis and hepatic progenitor cell activation

Irvine, K. M., Clouston, A. D., Blumenthal, A. and Powell, E. E. (2015). Blocking Wnt protein secretion from macrophages exacerbates liver fibrosis and hepatic progenitor cell activation. GESA-AGW and WGO International Congress, Gastroenterological Society of Australia Australian Gastroenterology Week, Brisbane, QLD, Australia, 28 September - 2 October 2015. Richmond, VIC, Australia: Wiley-Blackwell. doi: 10.1111/jgh.13087

Blocking Wnt protein secretion from macrophages exacerbates liver fibrosis and hepatic progenitor cell activation

2015

Conference Publication

Patterns of service utilisation within hepatology clinics: high prevalence of advanced liver disease

El-Atem, N., Wojcik, K., Horsfall, L., Irvine, K., Johnson, T., Mcphail, S. M. and Powell, E. E. (2015). Patterns of service utilisation within hepatology clinics: high prevalence of advanced liver disease. Gastro 2015 GESA-AGW and WGO International Congress, Gastroenterological Society of Australia Australian Gastroenterology Week 2015 | World Congress of Gastroenterology, Brisbane, Queensland, Australia, 28 September-2 October 2015. Richmond, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.13093

Patterns of service utilisation within hepatology clinics: high prevalence of advanced liver disease

2015

Conference Publication

Predicting clinical outcomes in chronic liver disease: the ELF test is superior to histology and simple scores

Irvine, Katharine, Wockner, Leesa F., Shanker, Mihir, Fagan, Kevin, Horsfall, Leigh, Fletcher, Linda, Ungerer, Jacobus, Pretorius, Carel J., Miller, Gregory, Clouston, Andrew D., Lampe, Guy and Powell, Elizabeth E. (2015). Predicting clinical outcomes in chronic liver disease: the ELF test is superior to histology and simple scores. 66th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD), San Francisco, CA, United States, 13-17 November 2015. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/hep.28218

Predicting clinical outcomes in chronic liver disease: the ELF test is superior to histology and simple scores