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2020 Journal Article Molybdenum enzymes and how they support virulence in pathogenic bacteriaZhong, Qifeng, Kobe, Bostjan and Kappler, Ulrike (2020). Molybdenum enzymes and how they support virulence in pathogenic bacteria. Frontiers in Microbiology, 11 615860, 1-23. doi: 10.3389/fmicb.2020.615860 |
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2020 Journal Article Vaccinia virus immunomodulator A46: destructive interactions with MAL and MyD88 shown by negative-stain electron microscopyAzar, Daniel F., Haas, Meryl, Fedosyuk, Sofiya, Rahaman, Md. Habibur, Hedger, Andrew, Kobe, Bostjan and Skern, Tim (2020). Vaccinia virus immunomodulator A46: destructive interactions with MAL and MyD88 shown by negative-stain electron microscopy. Structure, 28 (12), 1271-1287.e5. doi: 10.1016/j.str.2020.09.007 |
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2020 Journal Article Molecular basis of regio- and stereo-specificity in biosynthesis of bacterial heterodimeric diketopiperazinesSun, Chenghai, Luo, Zhenyao, Zhang, Wenlu, Tian, Wenya, Peng, Haidong, Lin, Zhi, Deng, Zixin, Kobe, Bostjan, Jia, Xinying and Qu, Xudong (2020). Molecular basis of regio- and stereo-specificity in biosynthesis of bacterial heterodimeric diketopiperazines. Nature Communications, 11 (1) 6251, 1-10. doi: 10.1038/s41467-020-20022-5 |
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2020 Journal Article Targeting multiple epitopes on the spike protein: a new hope for COVID-19 antibody therapySun, Yeping, Kobe, Bostjan and Qi, Jianxun (2020). Targeting multiple epitopes on the spike protein: a new hope for COVID-19 antibody therapy. Signal Transduction and Targeted Therapy, 5 (1) 208, 208. doi: 10.1038/s41392-020-00320-6 |
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2020 Journal Article Comprehensive analysis of IncC plasmid conjugation identifies a crucial role for the transcriptional regulator AcaBHancock, Steven J., Phan, Minh-Duy, Luo, Zhenyao, Lo, Alvin W., Peters, Kate M., Nhu, Nguyen Thi Khanh, Forde, Brian M., Whitfield, Jason, Yang, Ji, Strugnell, Richard A., Paterson, David L., Walsh, Timothy R., Kobe, Bostjan, Beatson, Scott A. and Schembri, Mark A. (2020). Comprehensive analysis of IncC plasmid conjugation identifies a crucial role for the transcriptional regulator AcaB. Nature Microbiology, 5 (11), 1340-1348. doi: 10.1038/s41564-020-0775-0 |
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2020 Journal Article All major cholesterol-dependent cytolysins use glycans as cellular receptorsShewell, Lucy K., Day, Christopher J., Jen, Freda E.-C., Haselhorst, Thomas, Atack, John M., Reijneveld, Josephine F., Everest-Dass, Arun, James, David B. A., Boguslawski, Kristina M., Brouwer, Stephan, Gillen, Christine M., Luo, Zhenyao, Kobe, Bostjan, Nizet, Victor, von Itzstein, Mark, Walker, Mark J., Paton, Adrienne W., Paton, James C., Torres, Victor J. and Jennings, Michael P. (2020). All major cholesterol-dependent cytolysins use glycans as cellular receptors. Science Advances, 6 (21) EAAZ4926, eaaz4926. doi: 10.1126/sciadv.aaz4926 |
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2020 Journal Article Evolutionary model of protein secondary structure capable of revealing new biological relationshipsLai, Jhih‐Siang, Rost, Burkhard, Kobe, Bostjan and Bodén, Mikael (2020). Evolutionary model of protein secondary structure capable of revealing new biological relationships. Proteins: Structure, Function, and Bioinformatics, 88 (9) prot.25898, 1251-1259. doi: 10.1002/prot.25898 |
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2019 Journal Article The structure and metal binding properties of Chlamydia trachomatis YtgALuo, Zhenyao, Neville, Stephanie L., Campbell, Rebecca, Morey, Jacqueline R., Menon, Shruti, Thomas, Mark, Eijkelkamp, Bart A., Ween, Miranda P., Huston, Wilhelmina M., Kobe, Bostjan and McDevitt, Christopher A. (2019). The structure and metal binding properties of Chlamydia trachomatis YtgA. Journal of Bacteriology, 202 (1) e00580. doi: 10.1128/jb.00580-19 |
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2019 Journal Article NAD+ cleavage activity by animal and plant TIR domains in cell death pathwaysHorsefield, Shane, Burdett, Hayden, Zhang, Xiaoxiao, Manik, Mohammad K., Shi, Yun, Chen, Jian, Qi, Tiancong, Gilley, Jonathan, Lai, Jhih-Siang, Rank, Maxwell X., Casey, Lachlan W., Gu, Weixi, Ericsson, Daniel J., Foley, Gabriel, Hughes, Robert O., Bosanac, Todd, von Itzstein, Mark, Rathjen, John P., Nanson, Jeffrey D., Boden, Mikael, Dry, Ian B., Williams, Simon J., Staskawicz, Brian J., Coleman, Michael P., Ve, Thomas, Dodds, Peter N. and Kobe, Bostjan (2019). NAD+ cleavage activity by animal and plant TIR domains in cell death pathways. Science, 365 (6455), 793-799. doi: 10.1126/science.aax1911 |
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2019 Journal Article The plant “resistosome”: structural insights into immune signalingBurdett, Hayden, Bentham, Adam R., Williams, Simon J., Dodds, Peter N., Anderson, Peter A., Banfield, Mark J. and Kobe, Bostjan (2019). The plant “resistosome”: structural insights into immune signaling. Cell Host and Microbe, 26 (2), 193-201. doi: 10.1016/j.chom.2019.07.020 |
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2019 Journal Article Animal NLRs continue to inform plant NLR structure and functionBurdett, Hayden, Kobe, Bostjan and Anderson, Peter A. (2019). Animal NLRs continue to inform plant NLR structure and function. Archives of Biochemistry and Biophysics, 670, 58-68. doi: 10.1016/j.abb.2019.05.001 |
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2019 Journal Article The single nucleotide polymorphism Mal-D96N mice provide new insights into functionality of Mal in TLR immune responsesDowling, Jennifer K., Tate, Michelle E., Bourke, Nollaig M., Bitto, Natalie, Lauterbach, Mario A., Cheung, Shane, Ve, Thomas, Kobe, Bostjan, Golenbock, Douglas and Mansell, Ashley (2019). The single nucleotide polymorphism Mal-D96N mice provide new insights into functionality of Mal in TLR immune responses. The Journal of Immunology, 202 (8), ji1800501-2396. doi: 10.4049/jimmunol.1800501 |
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2019 Journal Article Autoimmunity and effector recognition in Arabidopsis thaliana can be uncoupled by mutations in the RRS1-R immune receptorNewman, Toby E., Lee, Jungmin, Williams, Simon J., Choi, Sera, Halane, Morgan K., Zhou, Jun, Solomon, Peter, Kobe, Bostjan, Jones, Jonathan D. G., Segonzac, Cécile and Sohn, Kee Hoon (2019). Autoimmunity and effector recognition in Arabidopsis thaliana can be uncoupled by mutations in the RRS1-R immune receptor. New Phytologist, 222 (2), 954-965. doi: 10.1111/nph.15617 |
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2019 Journal Article Death, TIR, and RHIM: Self-assembling domains involved in innate immunity and cell-death signalingNanson, Jeffrey D., Kobe, Bostjan and Ve, Thomas (2019). Death, TIR, and RHIM: Self-assembling domains involved in innate immunity and cell-death signaling. Journal of Leukocyte Biology, 105 (2), 363-375. doi: 10.1002/JLB.MR0318-123R |
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2019 Journal Article Structural and functional insights into the modulation of the activity of a flax cytokinin oxidase by flax rust effector AvrL567-AWan, Li, Koeck, Markus, Williams, Simon J., Ashton, Anthony R., Lawrence, Gregory J., Sakakibara, Hitoshi, Kojima, Mikiko, Böttcher, Christine, Ericsson, Daniel J., Hardham, Adrienne R., Jones, David A., Ellis, Jeffrey G., Kobe, Bostjan and Dodds, Peter N. (2019). Structural and functional insights into the modulation of the activity of a flax cytokinin oxidase by flax rust effector AvrL567-A. Molecular Plant Pathology, 20 (2), 211-222. doi: 10.1111/mpp.12749 |
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2019 Journal Article Handling of nutrient copper in the bacterial envelopeStewart, Louisa J., Thaqi, Denis, Kobe, Bostjan, McEwan, Alastair G., Waldron, Kevin J. and Djoko, Karrera Y. (2019). Handling of nutrient copper in the bacterial envelope. Metallomics, 11 (1), 50-63. doi: 10.1039/c8mt00218e |
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2018 Journal Article Pathological mutations differentially affect the self-assembly and polymerisation of the innate immune system signalling adaptor molecule MyD88O'Carroll, Ailís, Chauvin, Brieuc, Brown, James W.P., Meagher, Ava, Coyle, Joanne, Schill, Jurgen, Bhumkhar, Akshay, Hunter, Dominic J.B., Ve, Thomas, Kobe, Bostjan, Sierecki, Emma and Gambin, Yann (2018). Pathological mutations differentially affect the self-assembly and polymerisation of the innate immune system signalling adaptor molecule MyD88. BMC Biology, 16 (149) 149, 149. doi: 10.1186/s12915-018-0611-7 |
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2018 Journal Article Megahertz serial crystallographyWiedorn, Max O., Oberthür, Dominik, Bean, Richard, Schubert, Robin, Werner, Nadine, Abbey, Brian, Aepfelbacher, Martin, Adriano, Luigi, Allahgholi, Aschkan, Al-Qudami, Nasser, Andreasson, Jakob, Aplin, Steve, Awel, Salah, Ayyer, Kartik, Bajt, Saša, Barák, Imrich, Bari, Sadia, Bielecki, Johan, Botha, Sabine, Boukhelef, Djelloul, Brehm, Wolfgang, Brockhauser, Sandor, Cheviakov, Igor, Coleman, Matthew A., Cruz-Mazo, Francisco, Danilevski, Cyril, Darmanin, Connie, Doak, R. Bruce, Domaracky, Martin ... Barty, Anton (2018). Megahertz serial crystallography. Nature Communications, 9 (1) 4025, 4025. doi: 10.1038/s41467-018-06156-7 |
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2018 Journal Article Antifungal benzo[b]thiophene 1,1-dioxide IMPDH inhibitors exhibit pan-assay interference (PAINS) profilesKummari, Lalith K., Butler, Mark S., Furlong, Emily, Blundell, Ross, Nouwens, Amanda, Silva, Alberto B., Kappler, Ulrike, Fraser, James A., Kobe, Bostjan, Cooper, Matthew A. and Robertson, Avril A.B. (2018). Antifungal benzo[b]thiophene 1,1-dioxide IMPDH inhibitors exhibit pan-assay interference (PAINS) profiles. Bioorganic and Medicinal Chemistry, 26 (20), 5408-5419. doi: 10.1016/j.bmc.2018.09.004 |
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2018 Journal Article Structural characterisation of the HT3 motif of the polyhistidine triad protein D from Streptococcus pneumoniaeLuo, Zhenyao, Pederick, Victoria G., Paton, James C., McDevitt, Christopher A. and Kobe, Bostjan (2018). Structural characterisation of the HT3 motif of the polyhistidine triad protein D from Streptococcus pneumoniae. FEBS letters, 592 (13), 2341-2350. doi: 10.1002/1873-3468.13122 |
