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2026 Journal Article The ASSIST CLAD study: a phase 2 randomized controlled trial of mesenchymal stromal cells for new-onset chronic lung allograft dysfunctionChambers, Daniel C., Westall, Glen, Darley, David, Musk, Michael, Glanville, Allan R., Malouf, Monique, Holmes-Liew, Chien-Li, Tan, Maxine, Apte, Simon H., Groves, Penelope L., Lutzky, Viviana P., Sturm, Marian J., Lawrence, Sharon, Lawson, Natalee, Singleton, Lisa, Timmins, Sjane, Enever, Debra, Wildermuth, Holly, Daka, Omega, Cooper, Brittany, Winks, Leslie, Haines, Sharon, Zhang, Lai-Ying, Levvey, Bronwyn, Cristiano, Yvonne, Yaw, Meow, Snell, Greg, Trotter, Michael, Carew, Alan ... Hopkins, Peter M.A. (2026). The ASSIST CLAD study: a phase 2 randomized controlled trial of mesenchymal stromal cells for new-onset chronic lung allograft dysfunction. The Journal of Heart and Lung Transplantation, 45 (8), 1310-1318. doi: 10.1016/j.healun.2026.03.032 |
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2026 Journal Article Clinical Evaluation of Long-Read Sequencing for Telomere Length Assessment in Human Blood and Lung TissuesLutzky, Viviana P., Rai, Subash K., Tan, Maxine E., Groves, Penny L., Knuckey, Kiara M., Mackintosh, John A., Jones, Mathew J. K., Apte, Simon H. and Chambers, Daniel C. (2026). Clinical Evaluation of Long-Read Sequencing for Telomere Length Assessment in Human Blood and Lung Tissues. Cells, 15 (13) 1165, 1165-1165. doi: 10.3390/cells15131165 |
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2026 Journal Article Single-cell transcriptomics of bronchoalveolar lavage reveals divergent macrophage subpopulations and trajectories in interstitial lung diseaseZhang, Lai-Ying, Allen, Peter C., Lutzky, Viviana P., Apte, Simon H., Groves, Penny L., Tan, Maxine E., De Silva, Tharushi, Spenceley, Eleanor R., McCloy, Rachael A., Nguyen, Quan H., Powell, Joseph E., Chambers, Daniel C. and O’Sullivan, Brendan J. (2026). Single-cell transcriptomics of bronchoalveolar lavage reveals divergent macrophage subpopulations and trajectories in interstitial lung disease. PLOS One, 21 (4) e0347852, 1-18. doi: 10.1371/journal.pone.0347852 |
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2026 Journal Article Alveolar lipid–macrophage networks at the intersection of pulmonary fibrosisApte, Simon H., Lutzky, Viviana P., Groves, Penny L. and Chambers, Daniel C. (2026). Alveolar lipid–macrophage networks at the intersection of pulmonary fibrosis. Cells, 15 (8) 668, 1-23. doi: 10.3390/cells15080668 |
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2026 Journal Article Proteome-wide serological profiling reveals broad elevation of EBV immunity in idiopathic pulmonary fibrosisSarathkumara, Yomani D., Knuckey, Kiara M., Lutzky, Viviana P., Groves, Penny L., Tan, Maxine E., Chambers, Daniel C., Proietti, Carla, Doolan, Denise L. and Apte, Simon H. (2026). Proteome-wide serological profiling reveals broad elevation of EBV immunity in idiopathic pulmonary fibrosis. International Journal of Molecular Sciences, 27 (2) 783, 1-14. doi: 10.3390/ijms27020783 |
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2026 Journal Article Treatment of Pseudomonas by removal of cloaking antibodies: is common polysaccharide antigen a factor?Monteith, Joshua N., Ledger, Emma L., Chamoun, Michelle N., Henderson, Ian R., Goldberg, Joanna B., Smith, Daniel, Chambers, Daniel C., Apte, Simon H. and Wells, Timothy J. (2026). Treatment of Pseudomonas by removal of cloaking antibodies: is common polysaccharide antigen a factor?. The Journal of Infectious Diseases, 233 (4) jiag002, e948-e956. doi: 10.1093/infdis/jiag002 |
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2025 Journal Article Silicosis research priorities for health care, research, and health and safety professionals, and for people exposed to silica in Australia: a research priority setting exerciseBarnes, Hayley, Mathieu, Sharna, Glass, Deborah C., Sim, Malcolm R., Fritschi, Lin, Dickinson, Joanne L., Chambers, Daniel C., Driscoll, Tim R., Edwards, Graeme, LaBranche, Nikky, Jones, Catherine, Bourke, Jane E., Hoy, Ryan F., Jenkins, Christine R., Apte, Simon, Holland, Anne and Tikellis, Gabriella (2025). Silicosis research priorities for health care, research, and health and safety professionals, and for people exposed to silica in Australia: a research priority setting exercise. Medical Journal of Australia, 223 (5), 257-264. doi: 10.5694/mja2.70013 |
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2025 Journal Article Transcriptomic plasticity of human alveolar macrophages revealed by single-cell RNA sequencing following drug exposure: implications for therapeutic developmentGroves, Penny L., Hockey, Levi, O’Sullivan, Brendan J., Zhang, Lai-Ying, Xiong, Zherui, Nguyen, Quan H., Tan, Maxine E., Lutzky, Viviana P., Davis, Rohan A., Chambers, Daniel C. and Apte, Simon H. (2025). Transcriptomic plasticity of human alveolar macrophages revealed by single-cell RNA sequencing following drug exposure: implications for therapeutic development. International Journal of Molecular Sciences, 26 (9) 4439, 4439. doi: 10.3390/ijms26094439 |
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2024 Journal Article Iron Alters the Transcriptome and Volatile Organic Compounds in the BAL of Patients with SilicosisAloe, Christian Anthony, Goh, Nicole Soo Leng, Wang, Hao, McQualter, Jonathan Luke, Doomun, Sheik Nadeem Elahee, De Souza, David, Pujari, Reshma, Papagianis, Paris Claris, Apte, Simon Hall, Barnes, Hayley, Vlahos, Ross, McDonald, Christine Faye, Hoy, Ryan Francis, Chambers, Daniel Charles, Leong, Tracy Li-Tsein and Bozinovski, Steven (2024). Iron Alters the Transcriptome and Volatile Organic Compounds in the BAL of Patients with Silicosis. American Journal of Respiratory Cell and Molecular Biology, 71 (5) PMID 8917225, 617-621. doi: 10.1165/rcmb.2024-0181le |
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2024 Journal Article Immunological landscapes in lung transplantation: Insights from T cell profiling in BAL and PBMCde Silva, Tharushi Ayanthika, Apte, Simon, Voisey, Joanne, Spann, Kirsten, Tan, Maxine, Chambers, Daniel and O’Sullivan, Brendan (2024). Immunological landscapes in lung transplantation: Insights from T cell profiling in BAL and PBMC. International Journal of Molecular Sciences, 25 (5) 2476, 1-16. doi: 10.3390/ijms25052476 |
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2023 Journal Article A methodological approach to identify natural compounds with antifibrotic activity and the potential to treat pulmonary fibrosis using single-cell sequencing and primary human lung macrophagesApte, Simon H., Groves, Penny L., Tan, Maxine E., Lutzky, Viviana P., de Silva, Tharushi, Monteith, Joshua N., Yerkovich, Stephanie T., O’Sullivan, Brendan J., Davis, Rohan A. and Chambers, Daniel C. (2023). A methodological approach to identify natural compounds with antifibrotic activity and the potential to treat pulmonary fibrosis using single-cell sequencing and primary human lung macrophages. International Journal of Molecular Sciences, 24 (20) 15104, 1-14. doi: 10.3390/ijms242015104 |
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2023 Journal Article Single-cell profiling of cells in the lung of a patient with chronic hypersensitivity pneumonitis reveals inflammatory niche with abundant CD39+ T cells with functional ATPase phenotype: A case studyde Silva, Tharushi Ayanthika, Apte, Simon, Voisey, Joanne, Spann, Kirsten, Tan, Maxine, Divithotawela, Chandima, Chambers, Daniel and O’Sullivan, Brendan (2023). Single-cell profiling of cells in the lung of a patient with chronic hypersensitivity pneumonitis reveals inflammatory niche with abundant CD39+ T cells with functional ATPase phenotype: A case study. International Journal of Molecular Sciences, 24 (19) 14442, 1-16. doi: 10.3390/ijms241914442 |
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2022 Journal Article Markers of rejection of a lung allograft: state of the artSilva, Tharushi de, Voisey, Joanne, Hopkins, Peter, Apte, Simon, Chambers, Daniel and O'Sullivan, Brendan (2022). Markers of rejection of a lung allograft: state of the art. Biomarkers in Medicine, 16 (6), 483-498. doi: 10.2217/bmm-2021-1013 |
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2022 Journal Article Alveolar crystal burden in stone workers with artificial stone silicosisApte, Simon H., Tan, Maxine E., Lutzky, Viviana P., De Silva, Tharushi A., Fiene, Andreas, Hundloe, Justin, Deller, David, Sullivan, Clair, Bell, Peter T. and Chambers, Daniel C. (2022). Alveolar crystal burden in stone workers with artificial stone silicosis. Respirology, 27 (6), 437-446. doi: 10.1111/resp.14229 |
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2022 Journal Article Proteomic identification of the contents of small extracellular vesicles from in vivo Plasmodium yoelii infectionDe Sousa, Karina P., Potriquet, Jeremy, Mulvenna, Jason, Sotillo, Javier, Groves, Penny L., Loukas, Alex, Apte, Simon H. and Doolan, Denise L. (2022). Proteomic identification of the contents of small extracellular vesicles from in vivo Plasmodium yoelii infection. International Journal for Parasitology, 52 (1), 35-45. doi: 10.1016/j.ijpara.2021.06.001 |
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2021 Journal Article TELO-SCOPE study: A randomised, double-blind, placebo-controlled, phase 2 trial of danazol for short telomere related pulmonary fibrosisMacKintosh, John A., Pietsch, Maria, Lutzky, Viviana, Enever, Debra, Bancroft, Sandra, Apte, Simon H., Tan, Maxine, Yerkovich, Stephanie T., Dickinson, Joanne L., Pickett, Hilda A., Selvadurai, Hiran, Grainge, Christopher, Goh, Nicole S., Hopkins, Peter, Glaspole, Ian, Reynolds, Paul N., Wrobel, Jeremy, Jaffe, Adam, Corte, Tamera J. and Chambers, Daniel C. (2021). TELO-SCOPE study: A randomised, double-blind, placebo-controlled, phase 2 trial of danazol for short telomere related pulmonary fibrosis. BMJ Open Respiratory Research, 8 (1) e001127, 1-8. doi: 10.1136/bmjresp-2021-001127 |
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2021 Journal Article Radiological outcomes of whole lung lavage for artificial stone-associated silicosisChambers, Daniel C., Apte, Simon H., Deller, David, Masel, Philip J., Jones, Catherine M., Newbigin, Katrina, Matula, Michael and Rapchuk, Ivan L. (2021). Radiological outcomes of whole lung lavage for artificial stone-associated silicosis. Respirology, 26 (5), 501-503. doi: 10.1111/resp.14018 |
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2020 Journal Article Chimeric Virus-Like Particles and Capsomeres Induce Similar CD8+ T Cell Responses but Differ in Capacity to Induce CD4+ T Cell Responses and Antibody ResponsesPattinson, David J., Apte, Simon H., Wibowo, Nani, Rivera-Hernandez, Tania, Groves, Penny L., Middelberg, Anton P. J. and Doolan, Denise L. (2020). Chimeric Virus-Like Particles and Capsomeres Induce Similar CD8+ T Cell Responses but Differ in Capacity to Induce CD4+ T Cell Responses and Antibody Responses. Frontiers in Immunology, 11 564627, 1-13. doi: 10.3389/fimmu.2020.564627 |
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2020 Journal Article Pulmonary alveolar proteinosis after lung transplantationDivithotawela, Chandima, Apte, Simon H., Tan, Maxine E., De Silva, Tharushi A. and Chambers, Daniel C. (2020). Pulmonary alveolar proteinosis after lung transplantation. Respirology Case Reports, 8 (5) e00566, e00566. doi: 10.1002/rcr2.566 |
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2020 Journal Article Successful treatment of telomeropathy‐related interstitial lung disease with immunosuppression and danazolChambers, Daniel C., Lutzky, Viviana P., Apte, Simon H., Godbolt, David, Feenstra, John and Mackintosh, John (2020). Successful treatment of telomeropathy‐related interstitial lung disease with immunosuppression and danazol. Respirology Case Reports, 8 (6) e00607, 1-3. doi: 10.1002/rcr2.607 |
