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2026

Journal Article

Non-Invasive Distal Airway Proteomics by Particles in Exhaled Air (PExA) Sampling Demonstrates Shared Proteomic Features with Matched Bronchoalveolar Lavage

Knuckey, Kiara M., Timmins, Sjane, Pham, Amy, Tan, Maxine E., Groves, Penny L., Lutzky, Viviana P., Rai, Subash K., Carew, Alan M., Chambers, Daniel C. and Apte, Simon H. (2026). Non-Invasive Distal Airway Proteomics by Particles in Exhaled Air (PExA) Sampling Demonstrates Shared Proteomic Features with Matched Bronchoalveolar Lavage. Biomolecules, 16 (10), 1396-1396. doi: 10.3390/biom16101396

Non-Invasive Distal Airway Proteomics by Particles in Exhaled Air (PExA) Sampling Demonstrates Shared Proteomic Features with Matched Bronchoalveolar Lavage

2026

Journal Article

The ASSIST CLAD study: a phase 2 randomized controlled trial of mesenchymal stromal cells for new-onset chronic lung allograft dysfunction

Chambers, Daniel C., Westall, Glen, Darley, David, Musk, Michael, Glanville, Allan R., Malouf, Monique, Holmes-Liew, Chien-Li, Tan, Maxine, Apte, Simon H., Groves, Penelope L., Lutzky, Viviana P., Sturm, Marian J., Lawrence, Sharon, Lawson, Natalee, Singleton, Lisa, Timmins, Sjane, Enever, Debra, Wildermuth, Holly, Daka, Omega, Cooper, Brittany, Winks, Leslie, Haines, Sharon, Zhang, Lai-Ying, Levvey, Bronwyn, Cristiano, Yvonne, Yaw, Meow, Snell, Greg, Trotter, Michael, Carew, Alan ... Hopkins, Peter M.A. (2026). The ASSIST CLAD study: a phase 2 randomized controlled trial of mesenchymal stromal cells for new-onset chronic lung allograft dysfunction. The Journal of Heart and Lung Transplantation, 45 (8), 1310-1318. doi: 10.1016/j.healun.2026.03.032

The ASSIST CLAD study: a phase 2 randomized controlled trial of mesenchymal stromal cells for new-onset chronic lung allograft dysfunction

2026

Journal Article

Clinical evaluation of long-read sequencing for telomere length assessment in human blood and lung tissues

Lutzky, Viviana P., Rai, Subash K., Tan, Maxine E., Groves, Penny L., Knuckey, Kiara M., Mackintosh, John A., Jones, Mathew J. K., Apte, Simon H. and Chambers, Daniel C. (2026). Clinical Evaluation of Long-Read Sequencing for Telomere Length Assessment in Human Blood and Lung Tissues. Cells, 15 (13) 1165, 1165-1165. doi: 10.3390/cells15131165

Clinical evaluation of long-read sequencing for telomere length assessment in human blood and lung tissues

2026

Journal Article

Single-cell transcriptomics of bronchoalveolar lavage reveals divergent macrophage subpopulations and trajectories in interstitial lung disease

Zhang, Lai-Ying, Allen, Peter C., Lutzky, Viviana P., Apte, Simon H., Groves, Penny L., Tan, Maxine E., De Silva, Tharushi, Spenceley, Eleanor R., McCloy, Rachael A., Nguyen, Quan H., Powell, Joseph E., Chambers, Daniel C. and O’Sullivan, Brendan J. (2026). Single-cell transcriptomics of bronchoalveolar lavage reveals divergent macrophage subpopulations and trajectories in interstitial lung disease. PLOS One, 21 (4) e0347852, 1-18. doi: 10.1371/journal.pone.0347852

Single-cell transcriptomics of bronchoalveolar lavage reveals divergent macrophage subpopulations and trajectories in interstitial lung disease

2026

Journal Article

Alveolar lipid–macrophage networks at the intersection of pulmonary fibrosis

Apte, Simon H., Lutzky, Viviana P., Groves, Penny L. and Chambers, Daniel C. (2026). Alveolar lipid–macrophage networks at the intersection of pulmonary fibrosis. Cells, 15 (8) 668, 1-23. doi: 10.3390/cells15080668

Alveolar lipid–macrophage networks at the intersection of pulmonary fibrosis

2026

Conference Publication

Deconvoluting fibrotic niches in idiopathic pulmonary fibrosis lungs using single-cell multiomics

Callen, Peter, Bartie, Caitlin, Tuzesi, Agota, Marx, Scarlett, McCloy, Rachael A., Sagi-Zsigmond, Eszter, Apte, Simon H., Tan, Maxine E., Chambers, Daniel C. and Powell, Joseph E. (2026). DECONVOLUTING FIBROTIC NICHES IN IDIOPATHIC PULMONARY FIBROSIS LUNGS USING SINGLE-CELL MULTIOMICS. HOBOKEN: WILEY.

Deconvoluting fibrotic niches in idiopathic pulmonary fibrosis lungs using single-cell multiomics

2026

Conference Publication

AI interpretation of broncho-alveolar lavage cytology for personalised pulmonary fibrosis care

Hockey, Levi, Xiong, Zherui, Kaur, Ashandeep, Apte, Simon H., Groves, Penny L., Tan, Maxine E., Lutzky, Viviana P., Knuckley, Kiara, Zhang, Lai-Ying, Timmins, Sjane, Carew, Alan, Nguyen, Quan and Chambers, Daniel C. (2026). AI interpretation of broncho-alveolar lavage cytology for personalised pulmonary fibrosis care. Unknown, Unknown, Unknown. Richmond, VIC Australia: John Wiley & Sons.

AI interpretation of broncho-alveolar lavage cytology for personalised pulmonary fibrosis care

2026

Journal Article

Proteome-wide serological profiling reveals broad elevation of EBV immunity in idiopathic pulmonary fibrosis

Sarathkumara, Yomani D., Knuckey, Kiara M., Lutzky, Viviana P., Groves, Penny L., Tan, Maxine E., Chambers, Daniel C., Proietti, Carla, Doolan, Denise L. and Apte, Simon H. (2026). Proteome-wide serological profiling reveals broad elevation of EBV immunity in idiopathic pulmonary fibrosis. International Journal of Molecular Sciences, 27 (2) 783, 1-14. doi: 10.3390/ijms27020783

Proteome-wide serological profiling reveals broad elevation of EBV immunity in idiopathic pulmonary fibrosis

2026

Journal Article

Treatment of Pseudomonas by removal of cloaking antibodies: is common polysaccharide antigen a factor?

Monteith, Joshua N., Ledger, Emma L., Chamoun, Michelle N., Henderson, Ian R., Goldberg, Joanna B., Smith, Daniel, Chambers, Daniel C., Apte, Simon H. and Wells, Timothy J. (2026). Treatment of Pseudomonas by removal of cloaking antibodies: is common polysaccharide antigen a factor?. The Journal of Infectious Diseases, 233 (4) jiag002, e948-e956. doi: 10.1093/infdis/jiag002

Treatment of Pseudomonas by removal of cloaking antibodies: is common polysaccharide antigen a factor?

2025

Journal Article

Silicosis research priorities for health care, research, and health and safety professionals, and for people exposed to silica in Australia: a research priority setting exercise

Barnes, Hayley, Mathieu, Sharna, Glass, Deborah C., Sim, Malcolm R., Fritschi, Lin, Dickinson, Joanne L., Chambers, Daniel C., Driscoll, Tim R., Edwards, Graeme, LaBranche, Nikky, Jones, Catherine, Bourke, Jane E., Hoy, Ryan F., Jenkins, Christine R., Apte, Simon, Holland, Anne and Tikellis, Gabriella (2025). Silicosis research priorities for health care, research, and health and safety professionals, and for people exposed to silica in Australia: a research priority setting exercise. Medical Journal of Australia, 223 (5), 257-264. doi: 10.5694/mja2.70013

Silicosis research priorities for health care, research, and health and safety professionals, and for people exposed to silica in Australia: a research priority setting exercise

2025

Journal Article

Transcriptomic plasticity of human alveolar macrophages revealed by single-cell RNA sequencing following drug exposure: implications for therapeutic development

Groves, Penny L., Hockey, Levi, O’Sullivan, Brendan J., Zhang, Lai-Ying, Xiong, Zherui, Nguyen, Quan H., Tan, Maxine E., Lutzky, Viviana P., Davis, Rohan A., Chambers, Daniel C. and Apte, Simon H. (2025). Transcriptomic plasticity of human alveolar macrophages revealed by single-cell RNA sequencing following drug exposure: implications for therapeutic development. International Journal of Molecular Sciences, 26 (9) 4439, 4439. doi: 10.3390/ijms26094439

Transcriptomic plasticity of human alveolar macrophages revealed by single-cell RNA sequencing following drug exposure: implications for therapeutic development

2025

Conference Publication

Efficacy and Safety of Danazol in Pulmonary Fibrosis Associated With Short Telomeres: A Phase 2 Randomized Clinical Trial

Mackintosh, J., Wells, J., Lutzky, V., Yerkovich, S.T., Yeh, R., Hsu, A., Pickett, H., Pietsch, M., Cooper, B., Enever, D., Bancroft, S., Apte, S., Tan, M., Dickinson, J., Lucas, S., Selvadurai, H., Grainge, C., Hopkins, P., Glaspole, I., Reynolds, P.N., Wrobel, J.P., Goh, N., Corte, T.J. and Chambers, D. (2025). Efficacy and Safety of Danazol in Pulmonary Fibrosis Associated With Short Telomeres: A Phase 2 Randomized Clinical Trial. ATS International Conference, San Francisco, CA United States, 16-21 May 2025. New York, NY United States: American Thoracic Society. doi: 10.1164/ajrccm.2025.211.abstracts.a1010

Efficacy and Safety of Danazol in Pulmonary Fibrosis Associated With Short Telomeres: A Phase 2 Randomized Clinical Trial

2025

Conference Publication

Iron alters the transcriptome and volatile organic compounds in the BAL of silicosis patients

Aloe, C., Goh, N., Wang, H., McQualter, J., Doomun, S., De Souza, D., Pujari, R., Papagianis, P., Apte, S., Barnes, H., Vlahos, R., McDonald, C., Hoy, R., Chambers, D., Leong, T. and Bozinovski, S. (2025). IRON ALTERS THE TRANSCRIPTOME AND VOLATILE ORGANIC COMPOUNDS IN THE BAL OF SILICOSIS PATIENTS. HOBOKEN: WILEY.

Iron alters the transcriptome and volatile organic compounds in the BAL of silicosis patients

2024

Journal Article

Iron Alters the Transcriptome and Volatile Organic Compounds in the BAL of Patients with Silicosis

Aloe, Christian Anthony, Goh, Nicole Soo Leng, Wang, Hao, McQualter, Jonathan Luke, Doomun, Sheik Nadeem Elahee, De Souza, David, Pujari, Reshma, Papagianis, Paris Claris, Apte, Simon Hall, Barnes, Hayley, Vlahos, Ross, McDonald, Christine Faye, Hoy, Ryan Francis, Chambers, Daniel Charles, Leong, Tracy Li-Tsein and Bozinovski, Steven (2024). Iron Alters the Transcriptome and Volatile Organic Compounds in the BAL of Patients with Silicosis. American Journal of Respiratory Cell and Molecular Biology, 71 (5) PMID 8917225, 617-621. doi: 10.1165/rcmb.2024-0181le

Iron Alters the Transcriptome and Volatile Organic Compounds in the BAL of Patients with Silicosis

2024

Conference Publication

Cellular Genomics of Bronchoalveolar Lavage Reveals Insight into Mechanisms of Human Pulmonary Fibrosis

Zhang, L.-Y., Apte, S., Lutzky, V., Groves, P., Tan, M., de Silva, T.A., Nguyen, Q., Powell, J., Chambers, D. and O'Sullivan, B. (2024). Cellular Genomics of Bronchoalveolar Lavage Reveals Insight into Mechanisms of Human Pulmonary Fibrosis. American Thoracic Society 2024 International Conference, San Diego, CA United States, 17-22 May 2024. New York, NY United States: American Thoracic Society. doi: 10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a2580

Cellular Genomics of Bronchoalveolar Lavage Reveals Insight into Mechanisms of Human Pulmonary Fibrosis

2024

Conference Publication

The Assist CLAD Study - Mesenchymal Stromal Cell Therapy in Chronic Lung Allograft Dysfunction

Chambers, D.C., Westall, G., Darley, D., Glanville, A., Malouf, M., Musk, M., Sturm, M., Holmes-Liew, C., Lawrence, S., Bushell, D., Holsworth, L., Lawson, N., Singleton, L., Timmins, S., Enever, D., Wildermuth, H., Daka, O., Cooper, B., Apte, S.H., Pham, A., Haines, S., Zhang, L., Tan, M., Groves, P., Lutzky, V.P., Levvey, B., Cristiano, Y., Yaw, M., Winks, L. ... Hopkins, P. (2024). The Assist CLAD Study - Mesenchymal Stromal Cell Therapy in Chronic Lung Allograft Dysfunction. ISHLT 44th Annual Meeting and Scientific Sessions, Prague, Czech Republic, 10-13 April 2024. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.healun.2024.02.016

The Assist CLAD Study - Mesenchymal Stromal Cell Therapy in Chronic Lung Allograft Dysfunction

2024

Conference Publication

Longitudinal Increases in Bronchoalveolar Lavage Interleukin-6, Interleukin-8, Macrophage Inflammatory Protein-1a, and Transforming Growth Factor ß Predict Progressive Chronic Lung Allograft Dysfunction

O'Sullivan, B., Tan, M., Apte, S.H., de Silva, T., Groves, P., Lutzky, V.P., Westall, G., Darley, D., Musk, M., Glanville, A., Malouf, M., Holmes-Liew, C., Sturm, M., Lawrence, S., Bushell, D., Holsworth, L., Lawson, N., Singleton, L., Timmins, S., Enever, D., Wildermuth, H., Daka, O., Cooper, B., Pham, A., Winks, L., Haines, S., Zhang, L., Levvey, B., Cristiano, Y. ... Chambers, D.C. (2024). Longitudinal Increases in Bronchoalveolar Lavage Interleukin-6, Interleukin-8, Macrophage Inflammatory Protein-1a, and Transforming Growth Factor ß Predict Progressive Chronic Lung Allograft Dysfunction. ISHLT 44th Annual Meeting and Scientific Sessions, Prague, Czech Republic, 10-13 April 2024. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.healun.2024.02.425

Longitudinal Increases in Bronchoalveolar Lavage Interleukin-6, Interleukin-8, Macrophage Inflammatory Protein-1a, and Transforming Growth Factor ß Predict Progressive Chronic Lung Allograft Dysfunction

2024

Conference Publication

Telomere length in Australian adults with pulmonary fibrosis

Mackintosh, J., Zhang, L., Lutzky, , Tan, M., Apte, S., Groves, P., O'Sullivan, B., Watson, S., Dixon, O., Hopkins, P., Corte, T. and Chambers, D. (2024). Telomere length in Australian adults with pulmonary fibrosis. HOBOKEN: WILEY.

Telomere length in Australian adults with pulmonary fibrosis

2024

Journal Article

Immunological landscapes in lung transplantation: Insights from T cell profiling in BAL and PBMC

de Silva, Tharushi Ayanthika, Apte, Simon, Voisey, Joanne, Spann, Kirsten, Tan, Maxine, Chambers, Daniel and O’Sullivan, Brendan (2024). Immunological landscapes in lung transplantation: Insights from T cell profiling in BAL and PBMC. International Journal of Molecular Sciences, 25 (5) 2476, 1-16. doi: 10.3390/ijms25052476

Immunological landscapes in lung transplantation: Insights from T cell profiling in BAL and PBMC

2023

Journal Article

A methodological approach to identify natural compounds with antifibrotic activity and the potential to treat pulmonary fibrosis using single-cell sequencing and primary human lung macrophages

Apte, Simon H., Groves, Penny L., Tan, Maxine E., Lutzky, Viviana P., de Silva, Tharushi, Monteith, Joshua N., Yerkovich, Stephanie T., O’Sullivan, Brendan J., Davis, Rohan A. and Chambers, Daniel C. (2023). A methodological approach to identify natural compounds with antifibrotic activity and the potential to treat pulmonary fibrosis using single-cell sequencing and primary human lung macrophages. International Journal of Molecular Sciences, 24 (20) 15104, 1-14. doi: 10.3390/ijms242015104

A methodological approach to identify natural compounds with antifibrotic activity and the potential to treat pulmonary fibrosis using single-cell sequencing and primary human lung macrophages