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2026 Journal Article The ASSIST CLAD study: a phase 2 randomized controlled trial of mesenchymal stromal cells for new-onset chronic lung allograft dysfunctionChambers, Daniel C., Westall, Glen, Darley, David, Musk, Michael, Glanville, Allan R., Malouf, Monique, Holmes-Liew, Chien-Li, Tan, Maxine, Apte, Simon H., Groves, Penelope L., Lutzky, Viviana P., Sturm, Marian J., Lawrence, Sharon, Lawson, Natalee, Singleton, Lisa, Timmins, Sjane, Enever, Debra, Wildermuth, Holly, Daka, Omega, Cooper, Brittany, Winks, Leslie, Haines, Sharon, Zhang, Lai-Ying, Levvey, Bronwyn, Cristiano, Yvonne, Yaw, Meow, Snell, Greg, Trotter, Michael, Carew, Alan ... Hopkins, Peter M.A. (2026). The ASSIST CLAD study: a phase 2 randomized controlled trial of mesenchymal stromal cells for new-onset chronic lung allograft dysfunction. The Journal of Heart and Lung Transplantation, 45 (8), 1310-1318. doi: 10.1016/j.healun.2026.03.032 |
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2026 Journal Article Clinical Evaluation of Long-Read Sequencing for Telomere Length Assessment in Human Blood and Lung TissuesLutzky, Viviana P., Rai, Subash K., Tan, Maxine E., Groves, Penny L., Knuckey, Kiara M., Mackintosh, John A., Jones, Mathew J. K., Apte, Simon H. and Chambers, Daniel C. (2026). Clinical Evaluation of Long-Read Sequencing for Telomere Length Assessment in Human Blood and Lung Tissues. Cells, 15 (13) 1165, 1165-1165. doi: 10.3390/cells15131165 |
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2026 Journal Article Single-cell transcriptomics of bronchoalveolar lavage reveals divergent macrophage subpopulations and trajectories in interstitial lung diseaseZhang, Lai-Ying, Allen, Peter C., Lutzky, Viviana P., Apte, Simon H., Groves, Penny L., Tan, Maxine E., De Silva, Tharushi, Spenceley, Eleanor R., McCloy, Rachael A., Nguyen, Quan H., Powell, Joseph E., Chambers, Daniel C. and O’Sullivan, Brendan J. (2026). Single-cell transcriptomics of bronchoalveolar lavage reveals divergent macrophage subpopulations and trajectories in interstitial lung disease. PLOS One, 21 (4) e0347852, 1-18. doi: 10.1371/journal.pone.0347852 |
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2026 Journal Article Alveolar lipid–macrophage networks at the intersection of pulmonary fibrosisApte, Simon H., Lutzky, Viviana P., Groves, Penny L. and Chambers, Daniel C. (2026). Alveolar lipid–macrophage networks at the intersection of pulmonary fibrosis. Cells, 15 (8) 668, 1-23. doi: 10.3390/cells15080668 |
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2026 Journal Article Proteome-wide serological profiling reveals broad elevation of EBV immunity in idiopathic pulmonary fibrosisSarathkumara, Yomani D., Knuckey, Kiara M., Lutzky, Viviana P., Groves, Penny L., Tan, Maxine E., Chambers, Daniel C., Proietti, Carla, Doolan, Denise L. and Apte, Simon H. (2026). Proteome-wide serological profiling reveals broad elevation of EBV immunity in idiopathic pulmonary fibrosis. International Journal of Molecular Sciences, 27 (2) 783, 1-14. doi: 10.3390/ijms27020783 |
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2026 Journal Article Treatment of Pseudomonas by removal of cloaking antibodies: is common polysaccharide antigen a factor?Monteith, Joshua N., Ledger, Emma L., Chamoun, Michelle N., Henderson, Ian R., Goldberg, Joanna B., Smith, Daniel, Chambers, Daniel C., Apte, Simon H. and Wells, Timothy J. (2026). Treatment of Pseudomonas by removal of cloaking antibodies: is common polysaccharide antigen a factor?. The Journal of Infectious Diseases, 233 (4) jiag002, e948-e956. doi: 10.1093/infdis/jiag002 |
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2025 Journal Article Silicosis research priorities for health care, research, and health and safety professionals, and for people exposed to silica in Australia: a research priority setting exerciseBarnes, Hayley, Mathieu, Sharna, Glass, Deborah C., Sim, Malcolm R., Fritschi, Lin, Dickinson, Joanne L., Chambers, Daniel C., Driscoll, Tim R., Edwards, Graeme, LaBranche, Nikky, Jones, Catherine, Bourke, Jane E., Hoy, Ryan F., Jenkins, Christine R., Apte, Simon, Holland, Anne and Tikellis, Gabriella (2025). Silicosis research priorities for health care, research, and health and safety professionals, and for people exposed to silica in Australia: a research priority setting exercise. Medical Journal of Australia, 223 (5), 257-264. doi: 10.5694/mja2.70013 |
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2025 Journal Article Transcriptomic plasticity of human alveolar macrophages revealed by single-cell RNA sequencing following drug exposure: implications for therapeutic developmentGroves, Penny L., Hockey, Levi, O’Sullivan, Brendan J., Zhang, Lai-Ying, Xiong, Zherui, Nguyen, Quan H., Tan, Maxine E., Lutzky, Viviana P., Davis, Rohan A., Chambers, Daniel C. and Apte, Simon H. (2025). Transcriptomic plasticity of human alveolar macrophages revealed by single-cell RNA sequencing following drug exposure: implications for therapeutic development. International Journal of Molecular Sciences, 26 (9) 4439, 4439. doi: 10.3390/ijms26094439 |
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2025 Conference Publication Efficacy and Safety of Danazol in Pulmonary Fibrosis Associated With Short Telomeres: A Phase 2 Randomized Clinical TrialMackintosh, J., Wells, J., Lutzky, V., Yerkovich, S.T., Yeh, R., Hsu, A., Pickett, H., Pietsch, M., Cooper, B., Enever, D., Bancroft, S., Apte, S., Tan, M., Dickinson, J., Lucas, S., Selvadurai, H., Grainge, C., Hopkins, P., Glaspole, I., Reynolds, P.N., Wrobel, J.P., Goh, N., Corte, T.J. and Chambers, D. (2025). Efficacy and Safety of Danazol in Pulmonary Fibrosis Associated With Short Telomeres: A Phase 2 Randomized Clinical Trial. ATS International Conference, San Francisco, CA United States, 16-21 May 2025. New York, NY United States: American Thoracic Society. doi: 10.1164/ajrccm.2025.211.abstracts.a1010 |
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2024 Journal Article Iron Alters the Transcriptome and Volatile Organic Compounds in the BAL of Patients with SilicosisAloe, Christian Anthony, Goh, Nicole Soo Leng, Wang, Hao, McQualter, Jonathan Luke, Doomun, Sheik Nadeem Elahee, De Souza, David, Pujari, Reshma, Papagianis, Paris Claris, Apte, Simon Hall, Barnes, Hayley, Vlahos, Ross, McDonald, Christine Faye, Hoy, Ryan Francis, Chambers, Daniel Charles, Leong, Tracy Li-Tsein and Bozinovski, Steven (2024). Iron Alters the Transcriptome and Volatile Organic Compounds in the BAL of Patients with Silicosis. American Journal of Respiratory Cell and Molecular Biology, 71 (5) PMID 8917225, 617-621. doi: 10.1165/rcmb.2024-0181le |
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2024 Conference Publication Cellular Genomics of Bronchoalveolar Lavage Reveals Insight into Mechanisms of Human Pulmonary FibrosisZhang, L.-Y., Apte, S., Lutzky, V., Groves, P., Tan, M., de Silva, T.A., Nguyen, Q., Powell, J., Chambers, D. and O'Sullivan, B. (2024). Cellular Genomics of Bronchoalveolar Lavage Reveals Insight into Mechanisms of Human Pulmonary Fibrosis. American Thoracic Society 2024 International Conference, San Diego, CA United States, 17-22 May 2024. New York, NY United States: American Thoracic Society. doi: 10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a2580 |
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2024 Journal Article Immunological landscapes in lung transplantation: Insights from T cell profiling in BAL and PBMCde Silva, Tharushi Ayanthika, Apte, Simon, Voisey, Joanne, Spann, Kirsten, Tan, Maxine, Chambers, Daniel and O’Sullivan, Brendan (2024). Immunological landscapes in lung transplantation: Insights from T cell profiling in BAL and PBMC. International Journal of Molecular Sciences, 25 (5) 2476, 1-16. doi: 10.3390/ijms25052476 |
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2023 Journal Article A methodological approach to identify natural compounds with antifibrotic activity and the potential to treat pulmonary fibrosis using single-cell sequencing and primary human lung macrophagesApte, Simon H., Groves, Penny L., Tan, Maxine E., Lutzky, Viviana P., de Silva, Tharushi, Monteith, Joshua N., Yerkovich, Stephanie T., O’Sullivan, Brendan J., Davis, Rohan A. and Chambers, Daniel C. (2023). A methodological approach to identify natural compounds with antifibrotic activity and the potential to treat pulmonary fibrosis using single-cell sequencing and primary human lung macrophages. International Journal of Molecular Sciences, 24 (20) 15104, 1-14. doi: 10.3390/ijms242015104 |
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2023 Journal Article Single-cell profiling of cells in the lung of a patient with chronic hypersensitivity pneumonitis reveals inflammatory niche with abundant CD39+ T cells with functional ATPase phenotype: A case studyde Silva, Tharushi Ayanthika, Apte, Simon, Voisey, Joanne, Spann, Kirsten, Tan, Maxine, Divithotawela, Chandima, Chambers, Daniel and O’Sullivan, Brendan (2023). Single-cell profiling of cells in the lung of a patient with chronic hypersensitivity pneumonitis reveals inflammatory niche with abundant CD39+ T cells with functional ATPase phenotype: A case study. International Journal of Molecular Sciences, 24 (19) 14442, 1-16. doi: 10.3390/ijms241914442 |
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2023 Conference Publication Late Breaking Abstract - Transcriptomic profiling identifies pro-fibrotic macrophages under ferroptotic stress in silicosisAloe, Christian, Goh, Nicole Soo Leng, Mcqualter, Jonathan, Pujari, Reshma, Cameron, Rhoda, Teague, Julie, Papagianis, Paris, Apte, Simon Hall, O'Sullivan, Brendan, Vlahos, Ross, Mcdonald, Christine Faye, Hoy, Ryan Francis, Chambers, Daniel Charles, Leong, Tracy Li-Tsein and Bozinovski, Steven (2023). Late Breaking Abstract - Transcriptomic profiling identifies pro-fibrotic macrophages under ferroptotic stress in silicosis. Annual Congress of the European-Respiratory-Society (ERS), Milan Ia, Sep 09-13, 2023. SHEFFIELD: EUROPEAN RESPIRATORY SOC JOURNALS LTD. doi: 10.1183/13993003.congress-2023.PA2233 |
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2022 Journal Article Markers of rejection of a lung allograft: state of the artSilva, Tharushi de, Voisey, Joanne, Hopkins, Peter, Apte, Simon, Chambers, Daniel and O'Sullivan, Brendan (2022). Markers of rejection of a lung allograft: state of the art. Biomarkers in Medicine, 16 (6), 483-498. doi: 10.2217/bmm-2021-1013 |
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2022 Journal Article Alveolar crystal burden in stone workers with artificial stone silicosisApte, Simon H., Tan, Maxine E., Lutzky, Viviana P., De Silva, Tharushi A., Fiene, Andreas, Hundloe, Justin, Deller, David, Sullivan, Clair, Bell, Peter T. and Chambers, Daniel C. (2022). Alveolar crystal burden in stone workers with artificial stone silicosis. Respirology, 27 (6), 437-446. doi: 10.1111/resp.14229 |
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2022 Journal Article Proteomic identification of the contents of small extracellular vesicles from in vivo Plasmodium yoelii infectionDe Sousa, Karina P., Potriquet, Jeremy, Mulvenna, Jason, Sotillo, Javier, Groves, Penny L., Loukas, Alex, Apte, Simon H. and Doolan, Denise L. (2022). Proteomic identification of the contents of small extracellular vesicles from in vivo Plasmodium yoelii infection. International Journal for Parasitology, 52 (1), 35-45. doi: 10.1016/j.ijpara.2021.06.001 |
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2021 Journal Article TELO-SCOPE study: A randomised, double-blind, placebo-controlled, phase 2 trial of danazol for short telomere related pulmonary fibrosisMacKintosh, John A., Pietsch, Maria, Lutzky, Viviana, Enever, Debra, Bancroft, Sandra, Apte, Simon H., Tan, Maxine, Yerkovich, Stephanie T., Dickinson, Joanne L., Pickett, Hilda A., Selvadurai, Hiran, Grainge, Christopher, Goh, Nicole S., Hopkins, Peter, Glaspole, Ian, Reynolds, Paul N., Wrobel, Jeremy, Jaffe, Adam, Corte, Tamera J. and Chambers, Daniel C. (2021). TELO-SCOPE study: A randomised, double-blind, placebo-controlled, phase 2 trial of danazol for short telomere related pulmonary fibrosis. BMJ Open Respiratory Research, 8 (1) e001127, 1-8. doi: 10.1136/bmjresp-2021-001127 |
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2021 Journal Article Radiological outcomes of whole lung lavage for artificial stone-associated silicosisChambers, Daniel C., Apte, Simon H., Deller, David, Masel, Philip J., Jones, Catherine M., Newbigin, Katrina, Matula, Michael and Rapchuk, Ivan L. (2021). Radiological outcomes of whole lung lavage for artificial stone-associated silicosis. Respirology, 26 (5), 501-503. doi: 10.1111/resp.14018 |
