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2020 Journal Article Chimeric Virus-Like Particles and Capsomeres Induce Similar CD8+ T Cell Responses but Differ in Capacity to Induce CD4+ T Cell Responses and Antibody ResponsesPattinson, David J., Apte, Simon H., Wibowo, Nani, Rivera-Hernandez, Tania, Groves, Penny L., Middelberg, Anton P. J. and Doolan, Denise L. (2020). Chimeric Virus-Like Particles and Capsomeres Induce Similar CD8+ T Cell Responses but Differ in Capacity to Induce CD4+ T Cell Responses and Antibody Responses. Frontiers in Immunology, 11 564627, 1-13. doi: 10.3389/fimmu.2020.564627 |
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2020 Journal Article Pulmonary alveolar proteinosis after lung transplantationDivithotawela, Chandima, Apte, Simon H., Tan, Maxine E., De Silva, Tharushi A. and Chambers, Daniel C. (2020). Pulmonary alveolar proteinosis after lung transplantation. Respirology Case Reports, 8 (5) e00566, e00566. doi: 10.1002/rcr2.566 |
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2020 Journal Article Successful treatment of telomeropathy‐related interstitial lung disease with immunosuppression and danazolChambers, Daniel C., Lutzky, Viviana P., Apte, Simon H., Godbolt, David, Feenstra, John and Mackintosh, John (2020). Successful treatment of telomeropathy‐related interstitial lung disease with immunosuppression and danazol. Respirology Case Reports, 8 (6) e00607, 1-3. doi: 10.1002/rcr2.607 |
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2020 Journal Article A population of CD4hi CD38hi T cells correlates with disease severity in patients with acute malariaApte, Simon H, Minigo, Gabriela, Groves, Penny L, Spargo, Jessie C, Plebanski, Magdalena, Grigg, Matthew J, Kenangalem, Enny, Burel, Julie G, Loughland, Jessica R, Flanagan, Katie L, Piera, Kim A, William, Timothy, Price, Ric N, Woodberry, Tonia, Barber, Bridget E, Anstey, Nicholas M and Doolan, Denise L (2020). A population of CD4hi CD38hi T cells correlates with disease severity in patients with acute malaria. Clinical and Translational Immunology, 9 (11) e1209, 1-18. doi: 10.1002/cti2.1209 |
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2019 Journal Article SMG1 heterozygosity exacerbates haematopoietic cancer development in Atm null mice by increasing persistent DNA damage and oxidative stressHo, Uda, Luff, John, James, Alexander, Lee, Cheok Soon, Quek, Hazel, Lai, Hui-Chi, Apte, Simon, Lim, Yi Chieh, Lavin, Martin F. and Roberts, Tara L. (2019). SMG1 heterozygosity exacerbates haematopoietic cancer development in Atm null mice by increasing persistent DNA damage and oxidative stress. Journal of Cellular and Molecular Medicine, 23 (12) jcmm.14685, 8151-8160. doi: 10.1111/jcmm.14685 |
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2019 Journal Article Chimeric Murine Polyomavirus Virus-Like Particles Induce Plasmodium Antigen-Specific CD8(+) T Cell and Antibody ResponsesPattinson, David J., Apte, Simon H., Wibowo, Nani, Chuan, Yap P., Rivera-Hernandez, Tania, Groves, Penny L., Lua, Linda H., Middelberg, Anton P. J. and Doolan, Denise L. (2019). Chimeric Murine Polyomavirus Virus-Like Particles Induce Plasmodium Antigen-Specific CD8(+) T Cell and Antibody Responses. Frontiers in Cellular and Infection Microbiology, 9 (JUN) 215, 215. doi: 10.3389/fcimb.2019.00215 |
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2018 Journal Article Defined Small Molecules Produced by Himalayan Medicinal Plants Display Immunomodulatory PropertiesWangchuk, Phurpa, Apte, Simon H., Smout, Michael J., Groves, Penny L., Loukas, Alex and Doolan, Denise L. (2018). Defined Small Molecules Produced by Himalayan Medicinal Plants Display Immunomodulatory Properties. International journal of molecular sciences, 19 (11) 3490, 3490. doi: 10.3390/ijms19113490 |
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2018 Journal Article The influence of physicochemical properties of lipopeptide adjuvants on immune response: a rationale for engineering a potent vaccineEskandari, Sharareh, Pattinson, David, Stephenson, Rachel J., Groves, Penny L., Apte, Simon H., Sedaghat, Bita, Chandurudu, Saranya, Doolan, Denise L. and Toth, Istvan (2018). The influence of physicochemical properties of lipopeptide adjuvants on immune response: a rationale for engineering a potent vaccine. Chemistry: A European Journal, 24 (39), 9892-9902. doi: 10.1002/chem.201801378 |
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2017 Journal Article Novel Plasmodium antigens identified via genome-based antibody screen induce protection associated with polyfunctional T cell responsesSchussek, Sophie, Trieu, Angela, Apte, Simon H., Sidney, John, Sette, Alessandro and Doolan, Denise L. (2017). Novel Plasmodium antigens identified via genome-based antibody screen induce protection associated with polyfunctional T cell responses. Scientific reports, 7 (1) 15053, 1-18. doi: 10.1038/s41598-017-15354-0 |
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2017 Conference Publication REDUCED <i>PLASMODIUM</i> BURDEN IN HUMANS ASSOCIATES WITH CD38<sub>+</sub> CD4<sub>+</sub> T CELLS DISPLAYING CYTOLYTIC POTENTIALBurel, Julie G., Apte, Simon H., Groves, Penny L., Klein, Kere, McCarthy, James S. and Doolan, Denise (2017). REDUCED PLASMODIUM BURDEN IN HUMANS ASSOCIATES WITH CD38+ CD4+ T CELLS DISPLAYING CYTOLYTIC POTENTIAL. 65th Annual Meeting of the American-Society-of-Tropical-Medicine-and-Hygiene (ASTMH), Atlanta Ga, Nov 13-16, 2016. MCLEAN: AMER SOC TROP MED & HYGIENE. |
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2017 Journal Article Dichotomous miR expression and immune responses following primary blood-stage malariaBurel, Julie G., Apte, Simon H., Groves, Penny L., Boyle, Michelle J., Langer, Christine, Beeson, James G., McCarthy, James S. and Doolan, Denise L. (2017). Dichotomous miR expression and immune responses following primary blood-stage malaria. JCI Insight, 2 (15) e93434. doi: 10.1172/jci.insight.93434 |
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2017 Journal Article Polyfunctional and IFN- monofunctional human CD4 T cell populations are molecularly distinctBurel, Julie G., Apte, Simon H., Groves, Penny L., McCarthy, James S. and Doolan, Denise L. (2017). Polyfunctional and IFN- monofunctional human CD4 T cell populations are molecularly distinct. JCI Insight, 2 (3) e87499, e87499. doi: 10.1172/jci.insight.87499 |
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2016 Journal Article Plasmodium vivax but not Plasmodium falciparum blood-stage infection in humans is associated with the expansion of a CD8+T cell population with cytotoxic potentialBurel, Julie G., Apte, Simon H., McCarthy, James S. and Doolan, Denise L. (2016). Plasmodium vivax but not Plasmodium falciparum blood-stage infection in humans is associated with the expansion of a CD8+T cell population with cytotoxic potential. PLoS Neglected Tropical Diseases, 10 (12) e0005031, e0005031. doi: 10.1371/journal.pntd.0005031 |
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2016 Journal Article Reduced Plasmodium parasite burden associates with CD38+ CD4+ T cells displaying cytolytic potential and impaired IFN-γ productionBurel, Julie G., Apte, Simon H., Groves, Penny L., Klein, Kerenaftali, McCarthy, James S. and Doolan, Denise L. (2016). Reduced Plasmodium parasite burden associates with CD38+ CD4+ T cells displaying cytolytic potential and impaired IFN-γ production. PLoS Pathogens, 12 (9) e1005839, e1005839. doi: 10.1371/journal.ppat.1005839 |
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2016 Journal Article Quantitative assessment of the functional plasticity of memory CD8+ T cellsBaz, Adriana, Groves, Penny, Buttigieg, Kathy, Apte, Simon H., Kienzle, Norbert and Kelso, Anne (2016). Quantitative assessment of the functional plasticity of memory CD8+ T cells. European Journal of Immunology, 46 (4), 863-873. doi: 10.1002/eji.201545726 |
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2016 Journal Article Synthesis of mannosylated lipopeptides with receptor targeting propertiesSedaghat, Bita, Stephenson, Rachel J., Giddam, Ashwini Kumar, Eskandari, Sharareh, Apte, Simon H., Pattinson, David J., Doolan, Denise L. and Toth, Istvan (2016). Synthesis of mannosylated lipopeptides with receptor targeting properties. Bioconjugate Chemistry, 27 (3), 533-548. doi: 10.1021/acs.bioconjchem.5b00547 |
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2016 Journal Article Systems approaches towards molecular profiling of human immunityBurel, Julie G., Apte, Simon H. and Doolan, Denise L. (2016). Systems approaches towards molecular profiling of human immunity. Trends in Immunology, 37 (1), 53-67. doi: 10.1016/j.it.2015.11.006 |
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2016 Journal Article Systematic evaluation of self-adjuvanting lipopeptide nano-vaccine platforms for the induction of potent CD8+ T-cell responsesApte, Simon H., Stephenson, Rachel J., Simerska, Pavla, Groves, Penny L., Aljohani, Salwa, Eskandari, Sharareh, Toth, Istvan and Doolan, Denise L. (2016). Systematic evaluation of self-adjuvanting lipopeptide nano-vaccine platforms for the induction of potent CD8+ T-cell responses. Nanomedicine, 11 (2), 137-152. doi: 10.2217/nnm.15.184 |
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2015 Journal Article Synthesis and characterisation of self-assembled and self-adjuvanting asymmetric multi-epitope lipopeptides of ovalbuminEskandari, Sharareh, Stephenson, Rachel J., Fuaad, Abdullah Ahmad, Apte, Simon H., Doolan, Denise L. and Toth, Istvan (2015). Synthesis and characterisation of self-assembled and self-adjuvanting asymmetric multi-epitope lipopeptides of ovalbumin. Chemistry - A European Journal, 21 (3), 1251-1261. doi: 10.1002/chem.201404997 |
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2015 Journal Article Development of a cytokine-secreting-based assay for the identification, sorting and transcriptomic analysis of polyfunctional human T cellsBurel, Julie G., Apte, Simon H. and Doolan, Denise L. (2015). Development of a cytokine-secreting-based assay for the identification, sorting and transcriptomic analysis of polyfunctional human T cells. European Cytokine Network, 26 (4), 67-72. doi: 10.1684/ecn.2015.0369 |
