Overview
Background
Associate Professor Melissa Eastgate is the Executive Director of Cancer Care Services at the RBWH, and the stream lead Metro North HHS Cancer Care Services. Melissa is the immediate past Chair of the Medical Oncology Group of Australia. Melissa completed her medical degree at the University of Queensland and gained her FRACP in Medical Onoclogy in 2004. Since then she has worked at the RBWH as a medical oncologist, with her main clinical interests being melanoma and gastrointestinal cancers, in which areas she is an active researcher. Melissa established the Melanoma MDT at the RBWH. Melissa supervises physician trainees throughout their training and is the previous Chair of the RACP Advanced Training Committee for Medical Oncology. Melissa has a strong interest in enabling access to care for patients, having provided outreach services to Bundaberg for nine years, and leading the establishment of the Telechemotherapy service in Longreach and Barcaldine.
Availability
- Associate Professor Melissa Eastgate is:
- Not available for supervision
Research interests
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Management of metastatic melanoma
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Management of gastrointestinal cancers
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Medical oncology training
Works
Search Professor Melissa Eastgate’s works on UQ eSpace
2023
Conference Publication
Chemoradiotherapy with concurrent durvalumab for the palliative treatment of oligometastatic esophageal and gastroesophageal carcinoma with dysphagia: A single arm phase 2 clinical trial, PALEO
Day, Fiona, Sridharan, Swetha, Michael, Michael, Christophersen, Louise, Moore, Melissa M., Eastgate, Melissa A., Thompson, Stephen, MWEEMPWA, ANGELA, Oldmeadow, Christopher, Fraser, Allison and Martin, Jarad (2023). Chemoradiotherapy with concurrent durvalumab for the palliative treatment of oligometastatic esophageal and gastroesophageal carcinoma with dysphagia: A single arm phase 2 clinical trial, PALEO. 2023 ASCO Annual Meeting, Chicago, IL United States, 2-6 June 2023. Alexandria, VA United States: American Society of Clinical Oncology. doi: 10.1200/jco.2023.41.16_suppl.tps4172
2023
Journal Article
Investigating the dietary knowledge, attitudes, and beliefs of Australian patients with cancer
Lee, Shu Fen, Brown, Teresa, Wyld, David, Edwards, Anna and Eastgate, Melissa (2023). Investigating the dietary knowledge, attitudes, and beliefs of Australian patients with cancer. Journal of Human Nutrition and Dietetics, 36 (3), 612-621. doi: 10.1111/jhn.13091
2022
Conference Publication
A multicenter, randomized, double-blind phase III study of HBI-8000 combined with nivolumab versus placebo with nivolumab in patients with unresectable or metastatic melanoma not previously treated with PD-1 or PD-L1 inhibitors
Khushalani, N.I., Shue, H., Gedye, C., Mazumder, A., Sharma, S., Eastgate, M., Majem Tarruella, M., Antonanzas Basa, M., Montaudie, H., Marais-Nieman, R., de la Cruz Merino, L., Clements, A., Mortier, L., Jameson, M., Shojaei, F., Ning, J., Aiyer, L., Gillings, M., Kabbinavar, F. and Ascierto, P. (2022). A multicenter, randomized, double-blind phase III study of HBI-8000 combined with nivolumab versus placebo with nivolumab in patients with unresectable or metastatic melanoma not previously treated with PD-1 or PD-L1 inhibitors. ESMO Asia Congress 2022, Singapore, 2-4 December 2022. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.annonc.2022.10.052
2022
Conference Publication
Adjuvant therapy in resected melanoma: Experience from royal brisbane and women's hospital
Turner, Cassie L. and Eastgate, Melissa (2022). Adjuvant therapy in resected melanoma: Experience from royal brisbane and women's hospital. HOBOKEN: WILEY.
2022
Journal Article
Toxicity and response to ipilimumab and nivolumab in older patients with metastatic melanoma: A multicentre retrospective analysis
Pathmanathan, Shivanshan, Babu, Hari, Dzienis, Marcin, Azer, Mary and Eastgate, Melissa (2022). Toxicity and response to ipilimumab and nivolumab in older patients with metastatic melanoma: A multicentre retrospective analysis. Pigment Cell and Melanoma Research, 35 (6), 587-594. doi: 10.1111/pcmr.13063
2022
Conference Publication
Cost-benefit of pre-treatment dihydropyrimidine dehydrogenase genotyping to individualise fluoropyrimidine-based chemotherapy in a contemporary Australian setting
Kim, Hansoo, Kulasegaran, Tivya, Eastgate, Melissa, Wyld, David, Burge, Matthew and Nalder, Mark (2022). Cost-benefit of pre-treatment dihydropyrimidine dehydrogenase genotyping to individualise fluoropyrimidine-based chemotherapy in a contemporary Australian setting. HOBOKEN: WILEY.
2022
Conference Publication
Tumour naive circulating tumour DNA (ctDNA) analysis in patients (pts) with resected colorectal cancer (CRC) in the phase III ASCOLT trial
Day, D., Starus, A., Lamik, A., Sieber, O., Begbie, S., Bonaventura, A., Rai, S., Karanth, N., Underhill, C. R., Nott, L. M., Van Hazel, G., Van Hagen, T., Wong, M., Saqib, A., Eastgate, M., Srivastav, R., Chia, J., Toh, H. C., Jones, F. and Segelov, E. (2022). Tumour naive circulating tumour DNA (ctDNA) analysis in patients (pts) with resected colorectal cancer (CRC) in the phase III ASCOLT trial. Annual Meeting of the European-Society-for-Medical-Oncology (ESMO), Electr Network, Sep 09-13, 2022. AMSTERDAM: ELSEVIER. doi: 10.1016/j.annonc.2022.07.518
2022
Conference Publication
Toxicity and response to ipilimumab and nivolumab in elderly patients with metastatic melanoma: A multicenter retrospective analysis
Pathmanathan, Shivanshan, Babu, Hari S., Dzienis, Marcin Radoslaw, Azer, Mary and Eastgate, Melissa A. (2022). Toxicity and response to ipilimumab and nivolumab in elderly patients with metastatic melanoma: A multicenter retrospective analysis. Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Electr Network, Jun 03-07, 2022. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.
2022
Journal Article
Selective targeting of protein kinase C (PKC)-θ nuclear translocation reduces mesenchymal gene signatures and reinvigorates dysfunctional CD8+ T cells in immunotherapy-resistant and metastatic cancers
Dunn, Jenny, McCuaig, Robert D., Tan, Abel H. Y., Tu, Wen Juan, Wu, Fan, Wagstaff, Kylie M., Zafar, Anjum, Ali, Sayed, Diwakar, Himanshu, Dahlstrom, Jane E., Bean, Elaine G., Forwood, Jade K., Tsimbalyuk, Sofiya, Cross, Emily M., Hardy, Kristine, Bain, Amanda L., Ahern, Elizabeth, Dolcetti, Riccardo, Mazzieri, Roberta, Yip, Desmond, Eastgate, Melissa, Malik, Laeeq, Milburn, Peter, Jans, David A. and Rao, Sudha (2022). Selective targeting of protein kinase C (PKC)-θ nuclear translocation reduces mesenchymal gene signatures and reinvigorates dysfunctional CD8+ T cells in immunotherapy-resistant and metastatic cancers. Cancers, 14 (6) 1596, 1596. doi: 10.3390/cancers14061596
2021
Journal Article
Catheter-associated bloodstream infection in patients with cancer: comparison of left- and right-sided insertions
Jones, M., Okano, S., Looke, D., Kennedy, G., Pavilion, G., Clouston, J., Van Kuilenburg, R., Geary, A., Joubert, W., Eastgate, M. and Mollee, P. (2021). Catheter-associated bloodstream infection in patients with cancer: comparison of left- and right-sided insertions. Journal of Hospital Infection, 118, 70-76. doi: 10.1016/j.jhin.2021.10.008
2021
Journal Article
The effects of a family-centered psychosocial-based nutrition intervention in patients with advanced cancer: the PiCNIC2 pilot randomised controlled trial
Molassiotis, Alex, Brown, Teresa, Cheng, Hui Lin, Byrnes, Angela, Chan, Raymond Javan, Wyld, David, Eastgate, Melissa, Yates, Patsy, Marshall, Andrea P, Fichera, Rebecca, Isenring, Liz, To, Ki Fung, Ko, Po Shan, Lam, Wang, Lam, Yuk Fong, Au, Lai Fan and Lo, Raymond See-kit (2021). The effects of a family-centered psychosocial-based nutrition intervention in patients with advanced cancer: the PiCNIC2 pilot randomised controlled trial. Nutrition Journal, 20 (1) 2, 2. doi: 10.1186/s12937-020-00657-2
2021
Journal Article
Surgical series of metastatic cerebral melanoma: clinical association of resection, BRAF-mutation status, and survival
Colditz, M.J., Lee, S.F., Eastgate, M., Elder, S., Brandis, P., Anderson, D., Withers, T., Jeffree, R.L., Pinkham, M.B. and Olson, S. (2021). Surgical series of metastatic cerebral melanoma: clinical association of resection, BRAF-mutation status, and survival. Interdisciplinary Neurosurgery, 24 101075, 101075. doi: 10.1016/j.inat.2020.101075
2021
Journal Article
Semiqualitative research protocol to explore cancer care workforce perceptions of the health system response to COVID-19 preparations in Southeast Queensland, Australia
Gasper, Harry, Ahern, Elizabeth, Roberts, Natasha, Chan, Bryan, Hughes, Brett, Kennedy, Glen, Wyld, David, Eastgate, Melissa and Lwin, Zarnie (2021). Semiqualitative research protocol to explore cancer care workforce perceptions of the health system response to COVID-19 preparations in Southeast Queensland, Australia. BMJ Open, 11 (5) e044655, e044655. doi: 10.1136/bmjopen-2020-044655
2020
Journal Article
Eftilagimod alpha, a soluble lymphocyte activation gene-3 (LAG-3) protein plus pembrolizumab in patients with metastatic melanoma
Atkinson, Victoria, Khattak, Adnan, Haydon, Andrew, Eastgate, Melissa, Roy, Amitesh, Prithviraj, Prashanth, Mueller, Christian, Brignone, Chrystelle and Triebel, Frederic (2020). Eftilagimod alpha, a soluble lymphocyte activation gene-3 (LAG-3) protein plus pembrolizumab in patients with metastatic melanoma. Journal for ImmunoTherapy of Cancer, 8 (2) e001681, 1-9. doi: 10.1136/jitc-2020-001681
2020
Conference Publication
Psychosocial impacts of COVID-19 on oncology workforces: metro versus regional Australia
Ahern, Elizabeth Stephanie, Gasper, Harry Michael, Chan, Bryan, Roberts, Natasha Anne, Hughes, Brett Gordon Maxwell, Wyld, David, Kennedy, Glen, Eastgate, Melissa A. and Lwin, Zarnie (2020). Psychosocial impacts of COVID-19 on oncology workforces: metro versus regional Australia. 2020 ASCO Quality Care Symposium, Chicago, IL USA, 9-10 October 2020. Alexandria, VA USA: American Society of Clinical Oncology. doi: 10.1200/jco.2020.38.29_suppl.111
2020
Conference Publication
Emotional impact of COVID-19 preparations on metro and regional cancer workforces in Queensland Australia: "We are all in this together"
Roberts, Natasha Anne, Chan, Bryan, Ahern, Elizabeth Stephanie, Gasper, Harry Michael, Kennedy, Glen, Hughes, Brett Gordon Maxwell, Wyld, David, Eastgate, Melissa A. and Lwin, Zarnie (2020). Emotional impact of COVID-19 preparations on metro and regional cancer workforces in Queensland Australia: "We are all in this together". 2020 ASCO Quality Care Symposium, Chicago, IL USA, 9-10 October 2020. Alexandria, VA USA: American Society of Clinical Oncology. doi: 10.1200/jco.2020.38.29_suppl.44
2020
Journal Article
Catheter-associated bloodstream infections in adults with cancer: a prospective randomized controlled trial
Mollee, P., Okano, S., Abro, E., Looke, D., Kennedy, G., Harper, J., Clouston, J., Van Kuilenburg, R., Geary, A., Joubert, W., Eastgate, M. and Jones, M. (2020). Catheter-associated bloodstream infections in adults with cancer: a prospective randomized controlled trial. Journal of Hospital Infection, 106 (2), 335-342. doi: 10.1016/j.jhin.2020.07.021
2020
Journal Article
Trends in epidemiology, treatment and molecular testing of metastatic colorectal cancer in a real‐world multi‐institution cohort study
Kuchel, Anna, Ahern, Elizabeth, Collins, Stephanie, Whitehall, Vicki, Okano, Satomi, Pelecanos, Anita, Wyld, David, Eastgate, Melissa and Burge, Matthew (2020). Trends in epidemiology, treatment and molecular testing of metastatic colorectal cancer in a real‐world multi‐institution cohort study. Asia-Pacific Journal of Clinical Oncology, 17 (1) ajco.13420, 84-93. doi: 10.1111/ajco.13420
2020
Journal Article
Supporting patients and carers affected by pancreatic cancer: a feasibility study of a counselling intervention
Beesley, Vanessa L., Turner, Jane M., Chan, Raymond J., Yates, Patsy, Gordon, Louisa G., Burge, Matthew, Eastgate, Melissa A., Staneva, Aleksandra A., Northfield, Sarah, Beebe, Hanna, Wyld, David K. and Neale, Rachel E. (2020). Supporting patients and carers affected by pancreatic cancer: a feasibility study of a counselling intervention. European Journal of Oncology Nursing, 46 101729, 101729. doi: 10.1016/j.ejon.2020.101729
2020
Journal Article
Tumor CD155 expression is associated with resistance to anti-PD1 immunotherapy in metastatic melanoma
Lepletier, Ailin, Madore, Jason, O'Donnell, Jake S., Johnston, Rebecca L., Li, Xian-Yang, McDonald, Elizabeth, Ahern, Elizabeth, Kuchel, Anna, Eastgate, Melissa, Pearson, Sally-Ann, Mallardo, Domenico, Ascierto, Paolo A., Massi, Daniela, Merelli, Barbara, Mandala, Mario, Wilmott, James S., Menzies, Alexander M., Leduc, Charles, Stagg, John, Routy, Bertrand, Long, Georgina V., Scolyer, Richard A., Bald, Tobias, Waddell, Nicola, Dougall, William C., Teng, Michele W. L. and Smyth, Mark J. (2020). Tumor CD155 expression is associated with resistance to anti-PD1 immunotherapy in metastatic melanoma. Clinical Cancer Research, 26 (14), 3671-3681. doi: 10.1158/1078-0432.ccr-19-3925
Media
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