Overview
Background
MBBS(Hons), FRACP — Specialist Respiratory and Lung Transplant Physician
Dr John Mackintosh graduated from The University of Queensland in 2011 with honours. He trained in respiratory medicine in Queensland, before completing an interstitial lung disease clinical fellowship at the Royal Brompton Hospital in London — one of the world's leading interstitial lung disease (ILD) referral centres.
He returned to Brisbane in 2019 as a Respiratory & Lung Transplant Physician with the Queensland Lung Transplant Service at The Prince Charles Hospital, and as an academic at The University of Queensland, where he was promoted to Associate Professor in recognition of his clinical and research contribution to ILD. He leads The Prince Charles Hospital's ILD service and his research work centres on ILD, with particular expertise in idiopathic pulmonary fibrosis, familial pulmonary fibrosis and the genetic underpinnings of fibrotic lung disease.
Alongside his clinical practice, he co-chairs the Queensland Statewide ILD Multidisciplinary Meeting and is founder and chair of the Australasian ILD Genetics Multidisciplinary Meeting. Internationally, he was a Co-Lead for the International Society of Heart and Lung Transplantation's first consensus statement on short telomere syndrome and lung transplantation, and is first author of the current Thoracic Society of Australia and New Zealand position statement on the treatment of IPF and progressive pulmonary fibrosis.
Availability
- Dr John Mackintosh is:
- Not available for supervision
Research impacts
Dr Mackintosh's research centres on interstitial lung disease, with a particular focus on the genetics of pulmonary fibrosis, telomere biology disorders and outcomes after lung transplantation.
Works
Search Professor John Mackintosh’s works on UQ eSpace
2026
Journal Article
The ASSIST CLAD study: a phase 2 randomized controlled trial of mesenchymal stromal cells for new-onset chronic lung allograft dysfunction
Chambers, Daniel C., Westall, Glen, Darley, David, Musk, Michael, Glanville, Allan R., Malouf, Monique, Holmes-Liew, Chien-Li, Tan, Maxine, Apte, Simon H., Groves, Penelope L., Lutzky, Viviana P., Sturm, Marian J., Lawrence, Sharon, Lawson, Natalee, Singleton, Lisa, Timmins, Sjane, Enever, Debra, Wildermuth, Holly, Daka, Omega, Cooper, Brittany, Winks, Leslie, Haines, Sharon, Zhang, Lai-Ying, Levvey, Bronwyn, Cristiano, Yvonne, Yaw, Meow, Snell, Greg, Trotter, Michael, Carew, Alan ... Hopkins, Peter M.A. (2026). The ASSIST CLAD study: a phase 2 randomized controlled trial of mesenchymal stromal cells for new-onset chronic lung allograft dysfunction. The Journal of Heart and Lung Transplantation, 45 (8), 1310-1318. doi: 10.1016/j.healun.2026.03.032
2026
Journal Article
Palivizumab for donor‐derived RSV infection in an adult bilateral lung transplant recipient: a case report
Meharry, Rosemary, Vale, Cassandra and Mackintosh, John (2026). Palivizumab for donor‐derived RSV infection in an adult bilateral lung transplant recipient: a case report. Respirology Case Reports, 14 (8) e70706, e70706. doi: 10.1002/rcr2.70706
2026
Journal Article
Inhaled treprostinil for idiopathic pulmonary fibrosis
Nathan, Steven D., Smith, Peter, Deng, Chunqin, De Salvo, Maria, Wuyts, Wim, Pavie-Gallegos, Juana, Song, Jin Woo, Kramer, Mordechai R., King, Christopher S., Mackintosh, John A., Chambers, Daniel, Miranda, Georgina Viviana, Breytenbach, Natalie, Peterson, Leigh, Bell, Heidi, Flaherty, Kevin R., Behr, Juergen and Cottin, Vincent (2026). Inhaled treprostinil for idiopathic pulmonary fibrosis. New England Journal of Medicine, 395 (2), 127-137. doi: 10.1056/NEJMoa2512911
2026
Journal Article
Deep-learning algorithm diagnostic support for usual interstitial pneumonia pattern recognition in fibrotic interstitial lung disease
Fermoyle, Caitlin C., Mackintosh, John A., Navaratnam, Vidya, Ellis, Samantha J., Cooper, Wendy A., Goh, Nicole S. L., Moodley, Yuben, Reynolds, Paul N., Zappala, Christopher J., Hopkins, Peter, Glaspole, Ian N., Corte, Tamera J., Walsh, Simon L. F., Accornero, Daniele, Agrawal, Aditya, Akilli, Isil Kibar, Alamoudi, Omer, Alberti, Maria Laura, Aliannejad, Rasoul, Aljahdali, Hamdan, Amanda, Gina, Anconina, Reut, Antuni, Julio Daniel, Aquaro, Giuseppe, Arenas-Jimenez, Juan, Asuquo, Bassey, Au-Yong, Iain, Avdeev, Sergey, Balbi, Maurizio ... Zompatori, Maurizio (2026). Deep-learning algorithm diagnostic support for usual interstitial pneumonia pattern recognition in fibrotic interstitial lung disease. Respirology, 31 (7), 711-720. doi: 10.1002/resp.70246
2026
Journal Article
Clinical evaluation of long-read sequencing for telomere length assessment in human blood and lung tissues
Lutzky, Viviana P., Rai, Subash K., Tan, Maxine E., Groves, Penny L., Knuckey, Kiara M., Mackintosh, John A., Jones, Mathew J. K., Apte, Simon H. and Chambers, Daniel C. (2026). Clinical Evaluation of Long-Read Sequencing for Telomere Length Assessment in Human Blood and Lung Tissues. Cells, 15 (13) 1165, 1165-1165. doi: 10.3390/cells15131165
2026
Journal Article
Idiopathic Pulmonary Fibrosis update, comparing the Australasian Interstitial Lung Disease Registry to the Australian Idiopathic Pulmonary Fibrosis Registry
Chee, Michelle, Khor, Yet Hong, Jackson, Dan, Cooper, Wendy, D’Costa, Jason, de Boer, Sally, Edwards, Adrienne, Ellis, Samantha, Gabbay, Eli, Gallagher, Henry, Glaspole, Ian, Goh, Nicole, Grainge, Christopher, Hopkins, Peter, Keir, Gregory, Kwan, Benjamin, Mackintosh, John, Moodley, Yuben, Moore, Irene, Navaratnam, Vidya, Ong, Chong, Reynolds, Paul, Royals, Karen, Teoh, Alan, Troy, Lauren, Veitch, Elizabeth, Wilsher, Margaret, Wrobel, Jeremy, Zappala, Chris ... on behalf of the AILDR Steering Committee (2026). Idiopathic Pulmonary Fibrosis update, comparing the Australasian Interstitial Lung Disease Registry to the Australian Idiopathic Pulmonary Fibrosis Registry. Internal Medicine Journal, 56 (9) imj.70490, 1518-1527. doi: 10.1111/imj.70490
2026
Conference Publication
International Mapping of Access to Genetic Testing for Interstitial Lung Disease (ILD)
Stanel, S., Lough, G., Emery, H., Adegunsoye, A. O., Aguiar, F. M., Bonella, F., Borie, R., Buendia-Roldan, , Chambers, D., Duckworth, A., Froidure, A., Hunninghake, G. M., Hurley, K. J., Johannson, K. A., Kam, M. L., Kulkarni, T., Mackintosh, J., Molina-Molina, M., Newton, C., Renzoni, E., Wolters, P., Zhang, D., Corte, T. J. and Rivera Ortega, P. (2026). International Mapping of Access to Genetic Testing for Interstitial Lung Disease (ILD). OXFORD: OXFORD UNIV PRESS. doi: 10.1093/ajrccm/aamag162.2493
2026
Journal Article
Ambulatory oxygen for treatment of exertional hypoxaemia in pulmonary fibrosis (PFOX): a multicentre, randomised, sham-controlled trial
Holland, Anne E, Hoffman, Mariana, Corte, Tamera J, Chambers, Daniel C, Hepworth, Graham, Ekström, Magnus P, Glaspole, Ian, Goh, Nicole S, Khor, Yet H, Palmer, Andrew J, Barton, Carly, Cox, Ingrid, Dowman, Leona, Einarsson, Jonas, Fuhrmeister, Lisa, Mackintosh, John A, Neglén, Pernilla, Prasad, Jyotika D, Bucciarelli, Jessica, Scherp, Simon, Sköld, Magnus, Smallwood, Natasha, Symons, Karen, Thompson, Michelle and McDonald, Christine F (2026). Ambulatory oxygen for treatment of exertional hypoxaemia in pulmonary fibrosis (PFOX): a multicentre, randomised, sham-controlled trial. The Lancet Respiratory Medicine, 14 (4), 317-326. doi: 10.1016/S2213-2600(26)00005-6
2026
Conference Publication
Palivizumab in donor derived RSV infection in an adult bilateral lung transplant recipient
Meharry, R.S., Vale, C., Winks, L., Vemuri, K., Tse, T., Carew, A., Chambers, D., Trotter, M., Fiene, A., Divithotawela, C., Bell, P., Zhang, L., Hopkins, P. and Mackintosh, J. (2026). Palivizumab in donor derived RSV infection in an adult bilateral lung transplant recipient. 46th Annual Meeting & Scientific Sessions of the International Society for Heart and Lung Transplantation (ISHLT) (ISHLT2026), Totonto, ON Canada, 22-26 April 2026. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.healun.2026.02.782
2026
Journal Article
Corrigendum to “Elastin distribution in lung tumours, including non-small cell lung Carcinoma”
Duhig, Edwina, Walsh, Michael, Lal, Sameeta, van Zwieten, Anthony, Broomfield, Amy, Stephens, Edward, Jaffrey, Daniel, Goldsworthy, Anita, Godbolt, David, Davidson, Morgan, Mackintosh, John, Hopkins, Peter, Chambers, Daniel, Bowman, Rayleen, Fong, Kwun and Yang, Ian (2026). Corrigendum to “Elastin distribution in lung tumours, including non-small cell lung Carcinoma”[Pathol 58 (supplement 1) S11]. Pathology, 58 (5), S11-642. doi: 10.1016/j.pathol.2026.03.003
2026
Conference Publication
The Australasian Interstitial Lung Disease Registry (AILDR): demographics, disease characteristics, and transplant-free survival insights from a bi-national cohort
Fraser, A., Zhao, C., Glaspole, , Glenn, L., Goh, N., Mackintosh, J., Symons, K., Wilsher, M., Chambers, D., D'Costa, J., de Boer, S., Edwards, A., Gabbay, E., Gallagher, H., Grainge, C., Keir, G., Khor, Y., Kwan, B., Lim, K. P., Moodley, Y., Moore, , Navaratnam, , Ong, C., Polasek, J., Reynolds, P., Teoh, A., Thien, F., Troy, L., Veitch, E. ... Corte, T. (2026). THE AUSTRALASIAN INTERSTITIAL LUNG DISEASE REGISTRY (AILDR): DEMOGRAPHICS, DISEASE CHARACTERISTICS, AND TRANSPLANT-FREE SURVIVAL INSIGHTS FROM A BI-NATIONAL COHORT. HOBOKEN: WILEY.
2026
Conference Publication
The relationship between anti-ro antibodies, phenotype and outcomes in the Australasian Interstitial Lung Disease Registry
Watson, Stella, Hansen, Dylan, Glaspole, Ian, Glenn, Laura, Goh, Nicole, Mackintosh, John, Symons, Karen, Wilsher, Margaret, Wrobel, Jeremy, Chambers, Daniel, D'costa, Jason, De Boer, Sally, Edwards, Adrienne, Gabbay, Eli, Gallagher, Henry, Grainge, Christopher, Keir, Gregory, Kwan, Ben, Lim, K. P., Moodley, Yuben, Moore, Irene, Navaratnam, Vidya, Ong, Chong, Polasek, Jonathon, Reynolds, Paul, Teoh, Alan, Thien, Frank, Troy, Lauren, Veitch, Elizabeth ... Parker, Matthew J. S. (2026). THE RELATIONSHIP BETWEEN ANTI-RO ANTIBODIES, PHENOTYPE AND OUTCOMES IN THE AUSTRALASIAN INTERSTITIAL LUNG DISEASE REGISTRY. HOBOKEN: WILEY.
2026
Journal Article
Relationship between pulmonary function and six-minute walk-test performance in ILD
Reeves, J., Roberston, L., Rogers, K., Zhao, C., Glaspole, , Glenn, L., Goh, N., Mackintosh, J., Symons, K., Wilsher, M., Chambers, D., D'costa, J., De Boer, S., Edwards, A., Gabbay, E., Gallagher, H., Grainge, C., Keir, G., Khor, Y., Kwan, B., Lim, Kp, Moodley, Y., Moore, , Navaratnam, , Ong, C., Polasek, J., Reynolds, P., Teoh, A., Thien, F. ... Corte, T. (2026). RELATIONSHIP BETWEEN PULMONARY FUNCTION AND SIX-MINUTE WALK-TEST PERFORMANCE IN ILD. HOBOKEN: WILEY.
2026
Conference Publication
Impact of the size of FVC decline on lung transplant-free survival among the Australasian Interstitial Lung Disease Registry (AILDR) patients
Li, Andrew, Stewart, Iain, Higginson, Emily, Buck, Evan, Teoh, Alan, Glenn, Laura, Troy, Lauren, Glaspole, Ian, Symons, Karen, Wilsher, Margaret, De Boer, Sally, Wrobel, Jeremy, Moodley, Yuben, Thien, Francis, Gallagher, Henry, Chambers, Daniel, Mackintosh, John, Goh, Nicole, Khor, Yet, Edwards, Adrienne, Grainge, Christopher, Kwan, Benjamin, Keir, Gregory, Ong, Chong, Reynolds, Paul, Veitch, Elizabeth, Gabbay, Eli, Pin, Lim Kuan, Polasek, Jonathon ... Corte, Tamera (2026). IMPACT OF THE SIZE OF FVC DECLINE ON LUNG TRANSPLANT-FREE SURVIVAL AMONG THE AUSTRALASIAN INTERSTITIAL LUNG DISEASE REGISTRY (AILDR) PATIENTS. HOBOKEN: WILEY.
2026
Conference Publication
Immunohistochemical expression within lung disease including carcinoma, with reference to cell lineage, the tumour microenvironment and elastin related proteins
Duhig, Edwina, van Zwieten, Anthony, Broomfield, Amy, Walsh, Michael, Lal, Sameeta, Godbolt, David, Davidson, Morgan, Mackintosh, John, Hopkins, Peter, Chambers, Daniel, Bowman, Rayleen, Fong, Kwun and Yang, Ian (2026). Immunohistochemical expression within lung disease including carcinoma, with reference to cell lineage, the tumour microenvironment and elastin related proteins. Pathology Update 2026, Sydney, NSW Australia, 6-8 March. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.pathol.2026.01.049
2026
Journal Article
Likelihood of usual interstitial pneumonia: a novel approach to prognosis for pulmonary fibrosis
Mackintosh, John A., Walsh, Simon L. F., Silva, Mario, Calandriello, Lucio, Humphries, Stephen M., Lynch, David A., Jo, Helen E., Glaspole, Ian, Grainge, Christopher, Goh, Nicole, Hopkins, Peter M. A., Moodley, Yuben, Reynolds, Paul N., Zappala, Christopher, Keir, Gregory, Cooper, Wendy A., Mahar, Annabelle M., Ellis, Samantha, Wells, Athol U. and Corte, Tamera J. (2026). Likelihood of Usual Interstitial Pneumonia: A Novel Approach to Prognosis for Pulmonary Fibrosis. Respirology, 31 (5) PMID 9616368, 521-529. doi: 10.1002/resp.70196
2026
Journal Article
Clearing the haze around familial interstitial lung abnormalities
Bajwa, Ramey and Mackintosh, John (2026). Clearing the haze around familial interstitial lung abnormalities. Thorax. doi: 10.1136/thorax-2026-225326
2026
Journal Article
Primed to React: Neutrophil-To-Lymphocyte Ratio to Predict Severe Checkpoint Inhibitor Pneumonitis
Mackintosh, John A. (2026). Primed to React: Neutrophil-To-Lymphocyte Ratio to Predict Severe Checkpoint Inhibitor Pneumonitis. Respirology, 31 (9), 864-865. doi: 10.1002/resp.70294
2026
Journal Article
Do we need to prioritise interstitial lung disease clinical diagnoses? A comment on the 2025 interstitial pneumonia statement
Fraser, Ashley, Tsai, Ling-Ling, Fermoyle, Caitlin C., Mortimer, Nathan, Troy, Lauren, Mackintosh, John, Chambers, Daniel C., Goh, Nicole, Milne, David, Wrobel, Jeremy, Wilsher, Margaret, de Boer, Sally, Parker, Matthew J S, Webster, Susanne, Baker, Amy, Hyde, Tania, Alison, Jennifer and Corte, Tamera J. (2026). Do we need to prioritise interstitial lung disease clinical diagnoses? A comment on the 2025 interstitial pneumonia statement. The European respiratory journal, 67 (1) 2501987, 2501987. doi: 10.1183/13993003.01987-2025
2025
Journal Article
A randomised clinical trial of a digital self-management package for people with interstitial lung disease: the REBUILD-SM protocol
Barton, Carly, Hoffman, Mariana, Cox, Narelle S., Glenn, Laura M., Lee, Joanna Y. T., Cox, Ingrid, Goh, Nicole S. L., Troy, Lauren K., Mackintosh, John, Chambers, Daniel C., Glaspole, Ian N., Gebski, Val, Keech, Anthony, Palmer, Andrew, Laranjo, Liliana, Knibbs, Luke D., Moodley, Yuben, Brooke, Mark, Holland, Anne E. and Corte, Tamera J. (2025). A randomised clinical trial of a digital self-management package for people with interstitial lung disease: the REBUILD-SM protocol. Respiratory Research, 27 (1) 14. doi: 10.1186/s12931-025-03442-z
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