Overview
Background
MBBS(Hons), FRACP — Specialist Respiratory and Lung Transplant Physician
Dr John Mackintosh graduated from The University of Queensland in 2011 with honours. He trained in respiratory medicine in Queensland, before completing an interstitial lung disease clinical fellowship at the Royal Brompton Hospital in London — one of the world's leading interstitial lung disease (ILD) referral centres.
He returned to Brisbane in 2019 as a Respiratory & Lung Transplant Physician with the Queensland Lung Transplant Service at The Prince Charles Hospital, and as an academic at The University of Queensland, where he was promoted to Associate Professor in recognition of his clinical and research contribution to ILD. He leads The Prince Charles Hospital's ILD service and his research work centres on ILD, with particular expertise in idiopathic pulmonary fibrosis, familial pulmonary fibrosis and the genetic underpinnings of fibrotic lung disease.
Alongside his clinical practice, he co-chairs the Queensland Statewide ILD Multidisciplinary Meeting and is founder and chair of the Australasian ILD Genetics Multidisciplinary Meeting. Internationally, he was a Co-Lead for the International Society of Heart and Lung Transplantation's first consensus statement on short telomere syndrome and lung transplantation, and is first author of the current Thoracic Society of Australia and New Zealand position statement on the treatment of IPF and progressive pulmonary fibrosis.
Availability
- Dr John Mackintosh is:
- Not available for supervision
Research impacts
Dr Mackintosh's research centres on interstitial lung disease, with a particular focus on the genetics of pulmonary fibrosis, telomere biology disorders and outcomes after lung transplantation.
Works
Search Professor John Mackintosh’s works on UQ eSpace
2024
Conference Publication
Telomere length in Australian adults with pulmonary fibrosis
Mackintosh, J., Zhang, L., Lutzky, , Tan, M., Apte, S., Groves, P., O'Sullivan, B., Watson, S., Dixon, O., Hopkins, P., Corte, T. and Chambers, D. (2024). Telomere length in Australian adults with pulmonary fibrosis. HOBOKEN: WILEY.
2024
Journal Article
Exertional desaturation during the 6-minute walk test versus daily life in people with fibrotic interstitial lung disease
Hoffman, Mariana, Burge, Angela T., Wong, Nick, McDonald, Christine F., Chambers, Daniel C., Glaspole, Ian, Mackintosh, John A., Ekstrom, Magnus, Sköld, Magnus, Goh, Nicole SL., Corte, Tamera J. and Holland, Anne E. (2024). Exertional desaturation during the 6-minute walk test versus daily life in people with fibrotic interstitial lung disease. CHEST, 165 (3), 632-635. doi: 10.1016/j.chest.2023.08.024
2024
Conference Publication
The utility of genetic testing in adults with pulmonary fibrosis: a retrospective cohort study
Dixon, O., Lutzky, , Zhang, L., Watson, S., Rodgers, D., Chambers, D. and Mackintosh, J. (2024). The utility of genetic testing in adults with pulmonary fibrosis: A retrospective cohort study. HOBOKEN: WILEY.
2024
Journal Article
Treatment of idiopathic pulmonary fibrosis and progressive pulmonary fibrosis: A position statement from the Thoracic Society of Australia and New Zealand 2023 revision
Mackintosh, John A., Keir, Gregory, Troy, Lauren K., Holland, Anne E., Grainge, Christopher, Chambers, Daniel C., Sandford, Debra, Jo, Helen E., Glaspole, Ian, Wilsher, Margaret, Goh, Nicole S. L., Reynolds, Paul N., Chapman, Sally, Mutsaers, Steven E., de Boer, Sally, Webster, Susanne, Moodley, Yuben and Corte, Tamera J. (2024). Treatment of idiopathic pulmonary fibrosis and progressive pulmonary fibrosis: A position statement from the Thoracic Society of Australia and New Zealand 2023 revision. Respirology, 29 (2), 105-135. doi: 10.1111/resp.14656
2024
Book Chapter
Post-Transplant Phase: Issues in the Early Postoperative Period
Mackintosh, John and Hopkins, Peter (2024). Post-Transplant Phase: Issues in the Early Postoperative Period. Textbook of Transplantation and Mechanical Support for End-Stage Heart and Lung Disease. (pp. 1217-1239) Hoboken, NJ United States: John Wiley & Sons. doi: 10.1002/9781119633884.ch89
2024
Journal Article
Telomere length and immunosuppression in non-idiopathic pulmonary fibrosis interstitial lung disease
Mackintosh, John A. and Chambers, Daniel C. (2024). Telomere length and immunosuppression in non-idiopathic pulmonary fibrosis interstitial lung disease. European Respiratory Journal, 63 (1) 2301806, 2301806. doi: 10.1183/13993003.01806-2023
2023
Journal Article
Long‐term exposure to low concentrations of air pollution and decline in lung function in people with idiopathic pulmonary fibrosis: Evidence from Australia
Zheng, Qiang, Cox, Ingrid A., Leigh, Lucy, de Graaff, Barbara, Johnston, Fay H., Corte, Tamera J., Knibbs, Luke D., Otahal, Petr, Navaratnam, Vidya, Campbell, Julie A., Glaspole, Ian, Moodley, Yuben, Hopkins, Peter, Mackintosh, John A., Ahmad, Hasnat, Walters, E. Haydn and Palmer, Andrew J. (2023). Long‐term exposure to low concentrations of air pollution and decline in lung function in people with idiopathic pulmonary fibrosis: Evidence from Australia. Respirology, 28 (10), 916-924. doi: 10.1111/resp.14552
2023
Conference Publication
Deep learning-based quantification of traction bronchiectasis severity for predicting outcome in idiopathic pulmonary fibrosis
Felder, Federico, Nan, Yang, Yang, Guang, Mackintosh, John, Calandriello, Lucio, Silva, Mario, Glaspole, Ian, Goh, Nicole, Cooper, Wendy, Grainge, Christopher, Hopkins, Peter, Moodley, Yuben, Vidya, Navaratnam, Reynolds, Paul, Wells, Athol, Corte, Tamera and Walsh, Simon (2023). Deep learning-based quantification of traction bronchiectasis severity for predicting outcome in idiopathic pulmonary fibrosis. Annual congress of the European-Respiratory-Society (ERS), Milan Ia, Sep 09-13, 2023. SHEFFIELD: EUROPEAN RESPIRATORY SOC JOURNALS LTD. doi: 10.1183/13993003.congress-2023.OA4853
2023
Conference Publication
A deep learning algorithm for predicting disease progression in idiopathic pulmonary fibrosis
Fang, Yingying, Felder, Federico, Yang, Guang, Mackintosh, John, Calandriello, Lucio, Silva, Mario, Cooper, Wendy, Glaspole, Ian, Goh, Nicole, Grainge, Christopher, Hopkins, Peter, Moodley, Yuben, Vidya, Navaratnam, Reynolds, Paul, Wells, Athol, Corte, Tamera and Walsh, Simon (2023). A deep learning algorithm for predicting disease progression in idiopathic pulmonary fibrosis. Annual congress of the European-Respiratory-Society (ERS), Milan Ia, Sep 09-13, 2023. SHEFFIELD: EUROPEAN RESPIRATORY SOC JOURNALS LTD. doi: 10.1183/13993003.congress-2023.OA4852
2023
Journal Article
Telomere biology disorder presenting acutely with pulmonary fibrosis and hepatopulmonary syndrome in a young adult male
Kung, Samantha Chin‐Yun, Dixon, Olivia, Kentwell, Sarah, Vasireddy, Raja S., Rodgers, Jonathan, Ding, Yuming, Rahman, Tony, Tallis, Caroline, Yang, Ian A. and Mackintosh, John A. (2023). Telomere biology disorder presenting acutely with pulmonary fibrosis and hepatopulmonary syndrome in a young adult male. Respirology Case Reports, 11 (8) e01182, 1-4. doi: 10.1002/rcr2.1182
2023
Journal Article
Preclinical interstitial lung disease in relatives of familial pulmonary fibrosis patients
Lucas, S. E. M., Raspin, K., Mackintosh, J., Glaspole, I., Reynolds, P. N., Chia, C., Grainge, C., Kendall, P., Troy, L., Schwartz, D. A., Wood-Baker, R., Walsh, S. L. F., Moodley, Y., Robertson, J., Macansh, S., Walters, E. H., Chambers, D., Corte, T.J. and Dickinson, J. L. (2023). Preclinical interstitial lung disease in relatives of familial pulmonary fibrosis patients. Pulmonology, 29 (3), 257-260. doi: 10.1016/j.pulmoe.2022.09.002
2023
Journal Article
Sex- and race-based differences in the treatment of interstitial lung diseases in North America And Australasia
Assayag, Deborah, Adegunsoye, Ayodeji, Sheehy, Robert, Morisset, Julie, Khalil, Nasreen, Johannson, Kerri A., Marcoux, Veronica, Kolb, Martin, Fisher, Jolene H., Manganas, Helene, Wrobel, Jeremy, Wilsher, Margaret, De Boer, Sally, Mackintosh, John, Chambers, Daniel C., Glaspole, Ian, Keir, Gregory J., Lee, Cathryn T., Jablonski, Renea, Vij, Rekha, Strek, Mary E., Corte, Tamera J. and Ryerson, Christopher J. (2023). Sex- and race-based differences in the treatment of interstitial lung diseases in North America And Australasia. Chest, 163 (5), 1156-1165. doi: 10.1016/j.chest.2022.12.039
2023
Conference Publication
Gender and treatment of interstitial lung disease: a registry study
Sheehy, R., Wrobel, J., Wilsher, M., de Boer, S., Mackintosh, J., Chambers, D., Glaspole, , Keir, G. and Corte, T. (2023). Gender and treatment of interstitial lung disease: A registry study. HOBOKEN: WILEY.
2023
Journal Article
Machine learning in radiology: the new frontier in interstitial lung diseases
Barnes, Hayley, Humphries, Stephen M., George, Peter M., Assayag, Deborah, Glaspole, Ian, Mackintosh, John A., Corte, Tamera J., Glassberg, Marilyn, Johannson, Kerri A., Calandriello, Lucio, Felder, Federico, Wells, Athol and Walsh, Simon (2023). Machine learning in radiology: the new frontier in interstitial lung diseases. The Lancet Digital Health, 5 (1), e41-e50. doi: 10.1016/S2589-7500(22)00230-8
2023
Journal Article
Multi-center evaluation of baseline neutrophil-to-lymphocyte (NLR) ratio as an independent predictor of mortality and clinical risk stratifier in idiopathic pulmonary fibrosis
Mikolasch, Theresia A., George, Peter M., Sahota, Jagdeep, Nancarrow, Thomas, Barratt, Shaney L., Woodhead, Felix A., Kouranos, Vasilis, Cope, Victoria S.A., Creamer, Andrew W., Fidan, Silan, Ganeshan, Balaji, Hoy, Luke, Mackintosh, John A., Shortman, Robert, Duckworth, Anna, Fallon, Janet, Garthwaite, Helen, Heightman, Melissa, Adamali, Huzaifa I., Lines, Sarah, Win, Thida, Wollerton, Rebecca, Renzoni, Elisabetta A., Steward, Matthew, Wells, Athol U., Gibbons, Michael, Groves, Ashley M., Gooptu, Bibek, Scotton, Chris J. and Porter, Joanna C. (2023). Multi-center evaluation of baseline neutrophil-to-lymphocyte (NLR) ratio as an independent predictor of mortality and clinical risk stratifier in idiopathic pulmonary fibrosis. eClinicalMedicine, 55 101758. doi: 10.1016/j.eclinm.2022.101758
2022
Book Chapter
Interstitial abnormalities from solid and haematological cancers
Mackintosh, John A., Duhig, Edwina E., Reddy, Taryn, Stephens, Edward K.H., Fong, Kwun M. and Yang, Ian A. (2022). Interstitial abnormalities from solid and haematological cancers. Lung diseases and cancer. (pp. 225-240) edited by Miguel Ángel Martínez-García, Mina Gaga, Kwun M. Fong and Peter M.A. Calverley. Sheffield, United Kingdom: European Respiratory Society. doi: 10.1183/2312508x.10020221
2022
Journal Article
Quantitative computed tomography predicts outcomes in idiopathic pulmonary fibrosis
Humphries, Stephen M., Mackintosh, John A., Jo, Helen E., Walsh, Simon L. F., Silva, Mario, Calandriello, Lucio, Chapman, Sally, Ellis, Samantha, Glaspole, Ian, Goh, Nicole, Grainge, Christopher, Hopkins, Peter M. A., Keir, Gregory J., Moodley, Yuben, Reynolds, Paul N., Walters, E. Haydn, Baraghoshi, David, Wells, Athol U., Lynch, David A. and Corte, Tamera J. (2022). Quantitative computed tomography predicts outcomes in idiopathic pulmonary fibrosis. Respirology, 27 (12), 1045-1053. doi: 10.1111/resp.14333
2022
Journal Article
Deep Learning-based Outcome Prediction in Progressive Fibrotic Lung Disease Using High-Resolution Computed Tomography
Walsh, Simon L. F., Mackintosh, John A., Calandriello, Lucio, Silva, Mario, Sverzellati, Nicola, Larici, Anna Rita, Humphries, Stephen M., Lynch, David A., Jo, Helen E., Glaspole, Ian, Grainge, Christopher, Goh, Nicole, Hopkins, Peter M. A., Moodley, Yuben, Reynolds, Paul N., Zappala, Christopher, Keir, Gregory, Cooper, Wendy A., Mahar, Annabelle M., Ellis, Samantha, Wells, Athol U. and Corte, Tamera J. (2022). Deep Learning-based Outcome Prediction in Progressive Fibrotic Lung Disease Using High-Resolution Computed Tomography. American Journal of Respiratory and Critical Care Medicine, 206 (7), 883-891. doi: 10.1164/rccm.202112-2684OC
2022
Journal Article
Airway complications—lung transplantation’s Achilles’ heel
Carew, Alan M. and Mackintosh, John A. (2022). Airway complications—lung transplantation’s Achilles’ heel. Journal of Thoracic Disease, 14 (9), 3116-3118. doi: 10.21037/jtd-22-889
2022
Journal Article
Towards truly ‘idiopathic’ pulmonary fibrosis
Mackintosh, John A. and Chambers, Daniel C. (2022). Towards truly ‘idiopathic’ pulmonary fibrosis. Respirology, 27 (9), 682-683. doi: 10.1111/resp.14320
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