Overview
Background
Dr Mark Jackson is a senior researcher at the Queensland Alliance for Agriculture and Food Innovation (QAAFI), where his research focuses on developing innovative approaches to sustainable crop protection. His early postdoctoral studies at the Institute for Molecular Biosciences (IMB-UQ) were split between the development of plant produced peptides as ecofriendly insecticides, and utilising plants as biofactories for recombinant products of value. At QAFFI Dr Jackson works closely with the sugar, citrus and vegetable industries on projects that aim to develop biological solutions to pest and diseases. A rewarding aspect of his career has been in training of research higher degree students.
Availability
- Dr Mark Jackson is:
- Available for supervision
Fields of research
Qualifications
- Bachelor (Honours), The University of Queensland
- Doctor of Philosophy, The University of Queensland
Works
Search Professor Mark Jackson’s works on UQ eSpace
2020
Journal Article
Make it or break it: plant AEPs on stage in biotechnology
Jackson, Mark A., Nguyen, Linh T. T., Gilding, Edward K., Durek, Thomas and Craik, David J. (2020). Make it or break it: plant AEPs on stage in biotechnology. Biotechnology Advances, 45 107651, 107651. doi: 10.1016/j.biotechadv.2020.107651
2020
Journal Article
Production of a structurally validated cyclotide in rice suspension cells is enabled by a supporting biosynthetic enzyme
Qu, Haiou, Jackson, Mark A., Yap, Kuok, Harvey, Peta J., Gilding, Edward K. and Craik, David J. (2020). Production of a structurally validated cyclotide in rice suspension cells is enabled by a supporting biosynthetic enzyme. Planta, 252 (6) 97, 97. doi: 10.1007/s00425-020-03505-z
2020
Journal Article
Insecticidal diversity of butterfly pea (Clitoria ternatea) accessions
Oguis, Georgianna K., Gilding, Edward K., Huang, Yen-Hua, Poth, Aaron G., Jackson, Mark A. and Craik, David J. (2020). Insecticidal diversity of butterfly pea (Clitoria ternatea) accessions. Industrial Crops and Products, 147 112214, 112214. doi: 10.1016/j.indcrop.2020.112214
2020
Journal Article
Circular permutation of the native enzyme-mediated cyclization position in cyclotides
Smithies, Bronwyn J., Huang, Yen-Hua, Jackson, Mark A., Yap, Kuok, Gilding, Edward K., Harris, Karen S., Anderson, Marilyn A. and Craik, David J. (2020). Circular permutation of the native enzyme-mediated cyclization position in cyclotides. ACS Chemical Biology, 15 (4) acschembio.9b00996, 962-969. doi: 10.1021/acschembio.9b00996
2019
Journal Article
A suite of kinetically superior AEP ligases can cyclise an intrinsically disordered protein
Harris, Karen S., Guarino, Rosemary F., Dissanayake, Ravindu S., Quimbar, Pedro, McCorkelle, Owen C., Poon, Simon, Kaas, Quentin, Durek, Thomas, Gilding, Edward K., Jackson, Mark A., Craik, David J., van der Weerden, Nicole L., Anders, Robin F. and Anderson, Marilyn A. (2019). A suite of kinetically superior AEP ligases can cyclise an intrinsically disordered protein. Scientific Reports, 9 (1) 10820, 10820. doi: 10.1038/s41598-019-47273-7
2019
Journal Article
Butterfly pea (Clitoria ternatea), a cyclotide-bearing plant with applications in agriculture and medicine
Oguis, Georgianna K., Gilding, Edward K., Jackson, Mark A. and Craik, David J. (2019). Butterfly pea (Clitoria ternatea), a cyclotide-bearing plant with applications in agriculture and medicine. Frontiers in Plant Science, 10 645, 645. doi: 10.3389/fpls.2019.00645
2019
Journal Article
Rapid and scalable plant-based production of a potent plasmin inhibitor peptide
Jackson, Mark A., Yap, Kuok, Poth, Aaron G., Gilding, Edward K., Swedberg, Joakim E., Poon, Simon, Qu, Haiou, Durek, Thomas, Harris, Karen, Anderson, Marilyn A. and Craik, David J. (2019). Rapid and scalable plant-based production of a potent plasmin inhibitor peptide. Frontiers in Plant Science, 10 602, 602. doi: 10.3389/fpls.2019.00602
2019
Journal Article
Papain-like cysteine proteases prepare plant cyclic peptide precursors for cyclization
Rehm, Fabian B. H., Jackson, Mark A., De Geyter, Ewout, Yap, Kuok, Gilding, Edward K., Durek, Thomas and Craik, David J. (2019). Papain-like cysteine proteases prepare plant cyclic peptide precursors for cyclization. Proceedings of the National Academy of Sciences, 116 (16), 7831-7836. doi: 10.1073/pnas.1901807116
2018
Journal Article
Molecular basis for the production of cyclic peptides by plant asparaginyl endopeptidases
Jackson, M. A., Gilding, E. K., Shafee, T., Harris, K. S., Kaas, Q., Poon, S., Yap, K., Jia, H., Guarino, R., Chan, L. Y., Durek, T., Anderson, M. A. and Craik, D. J. (2018). Molecular basis for the production of cyclic peptides by plant asparaginyl endopeptidases. Nature Communications, 9 (1) 2411, 2411. doi: 10.1038/s41467-018-04669-9
2018
Conference Publication
Co-expression of cyclizing capable asparaginyl endopeptidase enables efficient producton of cyclic peptides in planta
Jackson, M.A., Gilding, E.K., Durek, T., Anderson, M. and Craik, D.J. (2018). Co-expression of cyclizing capable asparaginyl endopeptidase enables efficient producton of cyclic peptides in planta. International Society of Plant Molecular Farming, Helsinki, Finland, 10 - 14 June 2018.
2017
Journal Article
Co-expression of a cyclizing asparaginyl endopeptidase enables efficient production of cyclic peptides in planta
Poon, Simon, Harris, Karen S, Jackson, Mark A, McCorkelle, Owen C, Gilding, Edward K, Durek, Thomas, van der Weerden, Nicole L, Craik, David J and Anderson, Marilyn A (2017). Co-expression of a cyclizing asparaginyl endopeptidase enables efficient production of cyclic peptides in planta. Journal of experimental botany, 69 (3), 633-641. doi: 10.1093/jxb/erx422
2016
Conference Publication
Design and plant-based production of therapeutic cyclic peptides
Craik, D., Oguis, G. K., Smithies, B., Qu, H., Gilding, E. K. and Jackson, M. A. (2016). Design and plant-based production of therapeutic cyclic peptides. 34th European Peptide Symposium, Leipzig, Germany, 4‐9 September 2016. Oxford, United Kingdom: John Wiley & Sons.
2015
Journal Article
Gene coevolution and regulation lock cyclic plant defence peptides to their targets
Gilding, Edward K., Jackson, Mark A., Poth, Aaron G., Henriques, Sonia Troeira, Prentis, Peter J., Mahatmanto, Tunjung and Craik, David J. (2015). Gene coevolution and regulation lock cyclic plant defence peptides to their targets. New Phytologist, 210 (2), 717-730. doi: 10.1111/nph.13789
2015
Conference Publication
Plants as production vehicles for cyclic therapeutic peptides
Jackson, M.A., Gilding, E.K., Jia, H. and Craik, D.J. (2015). Plants as production vehicles for cyclic therapeutic peptides. 3rd International Conference of Circular Peptides, Moreton Island, QLD, Australia, 1 -4 November 2015.
2015
Conference Publication
Plants as production vehicles for cyclic therapeutic peptides
Jackson, M.A., Gilding, E.K., Jia, H. and Craik, D.J. (2015). Plants as production vehicles for cyclic therapeutic peptides. Combio, Melbourne, VIC, Australia, 27 September - 1 October 2015.
2015
Book Chapter
Cyclotides in a biotechnological context: opportunities and challenges
Jackson, Mark A. and Gilding, Edward K. (2015). Cyclotides in a biotechnological context: opportunities and challenges. Plant cyclotides. (pp. 305-333) edited by David J. Craik. Amsterdam, Netherlands: Academic Press. doi: 10.1016/bs.abr.2015.09.010
2014
Journal Article
Design rules for efficient transgene expression in plants
Jackson M.A., Sternes, Peter R., Mudge, Stephen R., Graham, Michael W. and Birch, Robert G. (2014). Design rules for efficient transgene expression in plants. Plant Biotechnology Journal, 12 (7), 925-933. doi: 10.1111/pbi.12197
2013
Journal Article
Comparison of Agrobacterium and particle bombardment using whole plasmid or minimal cassette for production of high-expressing, low-copy transgenic plants
Jackson, Mark A., Anderson, David J. and Birch, Robert G. (2013). Comparison of Agrobacterium and particle bombardment using whole plasmid or minimal cassette for production of high-expressing, low-copy transgenic plants. Transgenic Research, 22 (1), 143-151. doi: 10.1007/s11248-012-9639-6
2011
Journal Article
A soluble acid invertase is directed to the vacuole by a signal anchor mechanism
Rae, Anne L., Casu, Rosanne E., Perroux, Jai M., Jackson, Mark A. and Grof, Christopher P. L. (2011). A soluble acid invertase is directed to the vacuole by a signal anchor mechanism. Journal of Plant Physiology, 168 (9), 983-989. doi: 10.1016/j.jplph.2010.11.003
2010
Journal Article
Comparative efficiency of subcellular targeting signals for expression of a toxic protein in sugarcane
Jackson, Mark A., Nutt, Kerry A., Hassall, Rachael and Rae, Anne L. (2010). Comparative efficiency of subcellular targeting signals for expression of a toxic protein in sugarcane. Functional Plant Biology, 37 (8), 785-793. doi: 10.1071/FP09243
Funding
Current funding
Supervision
Availability
- Dr Mark Jackson is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Biocontrol of pest and diseases of vegetable crops
Principal Advisor
Other advisors: Professor Andrew Geering, Dr Nipuni Peththa Thanthrige, Dr Nga Tran
-
Doctor Philosophy
Interactions between turnip yellows virus and its associated RNAs and impact on plant disease epidemiology
Associate Advisor
Other advisors: Professor Andrew Geering
Completed supervision
-
2026
Doctor Philosophy
Protein engineering for plant and microbial synthetic biology
Associate Advisor
Other advisors: Professor David Craik, Dr Nicole Lawrence
-
2024
Doctor Philosophy
Discovery, production, and application of plant cyclic peptides
Associate Advisor
Other advisors: Professor David Craik
-
2023
Doctor Philosophy
Nematicidal properties of natural cyclotides and expression of therapeutic cyclotides in plants
Associate Advisor
Other advisors: Professor David Craik
-
2022
Doctor Philosophy
Elucidating cyclotide biosynthetic pathways for plant-based recombinant expression
Associate Advisor
Other advisors: Professor David Craik
-
2020
Doctor Philosophy
From Farm to Pharm: Taking plant pharmaceuticals from research to production
Associate Advisor
Other advisors: Professor David Craik
-
2020
Doctor Philosophy
The compatibility of trypsin inhibitor cyclotides with plant-based recombinant expression systems
Associate Advisor
Other advisors: Professor David Craik
-
2019
Doctor Philosophy
Plant derived cyclic peptides: from discovery to biotechnological applications
Associate Advisor
Other advisors: Professor David Craik
-
2019
Doctor Philosophy
Clitoria ternatea (butterfly pea) cyclotides: Insights on functional diversity, regulation and biotechnological applications
Associate Advisor
Other advisors: Professor David Craik
-
2016
Doctor Philosophy
Harnessing Plants to Produce Cyclic Peptide Drugs
Associate Advisor
Other advisors: Professor David Craik
Media
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