Dr Maciej Trzaskowski
Dr

Maciej Trzaskowski

Email: 

Background

Dr Trzaskowski is Head of Research at Max Kelsen, providing supervision to 10 researchers and machine learning engineers, as well as 3 PhD students and 2 postdocs. He also holds a position of a visiting scientist at QIMR Berghofer Medical Research Institute and is an Associate Investigator at the ARC Centre of Excellence for Information Resilience (The University of Queensland) as well as the ARC Centre of Excellence for Automated Decision-Making and Society. He previously held the title of The British Academy Fellow aiming to improve utilisation of polygenic risk prediction in large population samples. He also underwent extensive training in a variety of Artificial Intelligence techniques such as Machine Learning and Multi-Agent Systems, with a specific focus on Agent Based Modelling, at University of Washington, Seattle, as well, as at the Department of Mathematics and Engineering, King's College London.

Availability

Dr Maciej Trzaskowski is:
Available for supervision

Qualifications

  • PhD in Statistical Genetics, University of London

Research impacts

My lab at Max Kelsen delivered ML-trained, RNA-based assay for detection of primary in cancer of unknown primary, which is currently trialed by QLD Health, SA and NT Pathology. We are also working on similar solutions for immunotherapy outcomes prediction and AI-aided pathways for discovery of novel cancer treatments. H-index: 40, citations: 9,127.

Search Professor Maciej Trzaskowski’s works on UQ eSpace

91 works between 2011 and 2026
All (91) Journal Article (79) Conference Publication (11) Book Chapter (1)

41 - 60 of 91 works

2018

Journal Article

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Adams, Mark J., Agerbo, Esben, Air, Tracy M., Andlauer, Till M. F., Bacanu, Silviu-Alin, Baekvad-Hansen, Marie, Beekman, Aartjan F. T., Bigdeli, Tim B., Binder, Elisabeth B., Blackwood, Douglas R. H., Bryois, Julien, Buttenschon, Henriette N., Bybjerg-Grauholm, Jonas, Cai, Na, Castelao, Enrique, Christensen, Jane Hvarregaard, Clarke, Toni-Kim, Coleman, Jonathan I. R., Colodro-Conde, Lucia, Couvy-Duchesne, Baptiste, Craddock, Nick, Crawford, Gregory E., Crowley, Cheynna A. ... Sullivan, Patrick F. (2018). Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression. Nature Genetics, 50 (5), 668-+. doi: 10.1038/s41588-018-0090-3

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

2018

Journal Article

Genetic influence on social outcomes during and after the Soviet era in Estonia

Rimfeld, Kaili, Krapohl, Eva, Trzaskowski, Maciej, Coleman, Jonathan R. I., Selzam, Saskia, Dale, Philip S., Esko, Tonu, Metspalu, Andres and Plomin, Robert (2018). Genetic influence on social outcomes during and after the Soviet era in Estonia. Nature Human Behaviour, 2 (4), 265-275. doi: 10.1038/s41562-018-0332-5

Genetic influence on social outcomes during and after the Soviet era in Estonia

2018

Journal Article

Improving genetic prediction by leveraging genetic correlations among human diseases and traits

Maier, Robert M, Zhu, Zhihong, Lee, Sang Hong, Trzaskowski, Maciej, Ruderfer, Douglas M, Stahl, Eli A, Ripke, Stephan, Wray, Naomi R, Yang, Jian, Visscher, Peter M and Robinson, Matthew R (2018). Improving genetic prediction by leveraging genetic correlations among human diseases and traits. Nature Communications, 9 (1) 989, 989. doi: 10.1038/s41467-017-02769-6

Improving genetic prediction by leveraging genetic correlations among human diseases and traits

2018

Journal Article

Causal associations between risk factors and common diseases inferred from GWAS summary data

Zhu, Zhihong, Zheng, Zhili, Zhang, Futao, Wu, Yang, Trzaskowski, Maciej, Maier, Robert, Robinson, Matthew R., McGrath, John J, Visscher, Peter M, Wray, Naomi R and Yang, Jian (2018). Causal associations between risk factors and common diseases inferred from GWAS summary data. Nature Communications, 9 (1) 224, 224. doi: 10.1038/s41467-017-02317-2

Causal associations between risk factors and common diseases inferred from GWAS summary data

2018

Journal Article

Association of whole-genome and NETRIN1 signaling pathway–derived polygenic risk scores for major depressive disorder and white matter microstructure in the UK Biobank

Barbu, Miruna C., Zeng, Yanni, Shen, Xueyi, Cox, Simon R., Clarke, Toni-Kim, Gibson, Jude, Adams, Mark J., Johnstone, Mandy, Haley, Chris S., Lawrie, Stephen M., Deary, Ian J., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Adams, Mark J., Agerbo, Esben, Air, Tracy M., Andlauer, Till F.M., Bacanu, Silviu-Alin, Bækvad-Hansen, Marie, Beekman, Aartjan T.F., Bigdeli, Tim B., Binder, Elisabeth B., Blackwood, Douglas H.R., Bryois, Julien ... Whalley, Heather C. (2018). Association of whole-genome and NETRIN1 signaling pathway–derived polygenic risk scores for major depressive disorder and white matter microstructure in the UK Biobank. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 4 (1), 91-100. doi: 10.1016/j.bpsc.2018.07.006

Association of whole-genome and NETRIN1 signaling pathway–derived polygenic risk scores for major depressive disorder and white matter microstructure in the UK Biobank

2018

Conference Publication

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depressive disorder

Trzaskowski, Maciej, Wray, Naomi and Sullivan, Patrick (2018). Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depressive disorder. Human Genome Meeting 2018, Yokohama, Japan, 12-15 March 2018. London, United Kingdom: BioMed Central . doi: 10.1186/s40246-018-0138-6

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depressive disorder

2018

Conference Publication

Higher genetic risk for schizophrenia is associated with living in more densely populated areas

Conde, Lucia Colodro, Couvy-Duchesne, Baptiste, Whitfield, John, Streit, Fabian, Yengo, Loic, Trzaskowski, Maciej, De Zeeuw, Eveline, Nivard, Michel, Whiteman, David, Boomsma, Dorret, Yang, Jian, Rietschel, Marcella, Mcgrath, John, Medland, Sarah and Martin, Nick (2018). Higher genetic risk for schizophrenia is associated with living in more densely populated areas. 48th Annual Meeting of the Behavior Genetics Association (BGA), Boston, MA United States, 20-23 June 2018. New York, NY United States: Springer.

Higher genetic risk for schizophrenia is associated with living in more densely populated areas

2017

Journal Article

Hair Cortisol in Twins: Heritability and Genetic Overlap with Psychological Variables and Stress-System Genes

Rietschel, Liz, Streit, Fabian, Zhu, Gu, McAloney, Kerrie, Frank, Josef, Couvy-Duchesne, Baptiste, Witt, Stephanie H., Binz, Tina M., Bolton, Jennifer L., Hayward, Caroline, Direk, Nese, Anderson, Anna, Huffman, Jennifer, Wilson, James F., Campbell, Harry, Rudan, Igor, Wright, Alan, Hastie, Nicholas, Wild, Sarah H., Velders, Fleur P., Hofman, Albert, Uitterlinden, Andre G., Lahti, Jari, Räikkönen, Katri, Kajantie, Eero, Widen, Elisabeth, Palotie, Aarno, Eriksson, Johan G., Kaakinen, Marika ... Rietschel, Marcella (2017). Hair Cortisol in Twins: Heritability and Genetic Overlap with Psychological Variables and Stress-System Genes. Scientific Reports, 7 (1) 15351, 15351. doi: 10.1038/s41598-017-11852-3

Hair Cortisol in Twins: Heritability and Genetic Overlap with Psychological Variables and Stress-System Genes

2017

Journal Article

Genetic effects influencing risk for major depressive disorder in China and Europe

Bigdeli, T. B., Ripke, S., Peterson, R. E., Trzaskowski, M., Bacanu, S-A, Abdellaoui, A., Andlauer, T. F. M., Beekman, A. T. F., Berger, K., Blackwood, D. H. R., Boomsma, D. I., Breen, G., Buttenschon, H. N., Byrne, E. M., Cichon, S., Clarke, T-K, Couvy-Duchesne, B., Craddock, N., de Geus, E. J. C., Degenhardt, F., Dunn, E. C., Edwards, A. C., Fanous, A. H., Forstner, A. J., Frank, J., Gill, M., Gordon, S. D., Grabe, H. J., Hamilton, S. P. ... Kendler, K. S. (2017). Genetic effects influencing risk for major depressive disorder in China and Europe. Translational Psychiatry, 7 (3) e1074, e1074-e1074. doi: 10.1038/tp.2016.292

Genetic effects influencing risk for major depressive disorder in China and Europe

2016

Journal Article

Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses (vol 48, pg 624, 2016)

Okbay, Aysu, Baselmans, Bart M. L., De Neve, Jan-Emmanuel, Turley, Patrick, Nivard, Michel G., Fontana, Mark Alan, Meddens, S. Fleur W., Linner, Richard Karlsson, Rietveld, Cornelius A., Derringer, Jaime, Gratten, Jacob, Lee, James J., Liu, Jimmy Z., de Vlaming, Ronald, Ahluwalia, Tarunveer S., Buchwald, Jadwiga, Cavadino, Alana, Frazier-Wood, Alexis C., Furlotte, Nicholas A., Garfield, Victoria, Geisel, Marie Henrike, Gonzalez, Juan R., Haitjema, Saskia, Karlsson, Robert, van der Laan, Sander W., Ladwig, Karl-Heinz, Lahti, Jari, van der Lee, Sven J., Lind, Penelope A. ... Cesarini, David (2016). Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses (vol 48, pg 624, 2016). Nature Genetics, 48 (12), 1591-1591. doi: 10.1038/ng1216-1587b

Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses (vol 48, pg 624, 2016)

2016

Journal Article

A genome-wide association meta-analysis of attention-deficit/hyperactivity disorder symptoms in population-based pediatric cohorts

Middeldorp, Christel M., Hammerschlag, Anke R., Ouwens, Klaasjan G., Groen-Blokhuis, Maria M., St Pourcain, Beate, Greven, Corina U., Pappa, Irene, Tiesler, Carla M. T., Ang, Wei, Nolte, Ilja M., Vilor-Tejedor, Natalia, Bacelis, Jonas, Ebejer, Jane L., Zhao, Huiying, Davies, Gareth E., Ehli, Erik A., Evans, David M., Fedko, Iryna O., Guxens, Monica, Hottenga, Jouke-Jan, Hudziak, James J., Jugessur, Astanand, Kemp, John P., Krapohl, Eva, Martin, Nicholas G., Murcia, Mario, Myhre, Ronny, Ormel, Johan, Ring, Susan M. ... Boomsma, Dorret I. (2016). A genome-wide association meta-analysis of attention-deficit/hyperactivity disorder symptoms in population-based pediatric cohorts. Journal of the American Academy of Child and Adolescent Psychiatry, 55 (10), 896-905.e6. doi: 10.1016/j.jaac.2016.05.025

A genome-wide association meta-analysis of attention-deficit/hyperactivity disorder symptoms in population-based pediatric cohorts

2016

Journal Article

Genetic correlation analysis suggests association between increased self-reported sleep duration in adults and schizophrenia and type 2 diabetes

Byrne, Enda M., Gehrman, Philip R., Trzaskowski, Maciej, Tiemeier, Henning and Pack, Allan I. (2016). Genetic correlation analysis suggests association between increased self-reported sleep duration in adults and schizophrenia and type 2 diabetes. Sleep, 39 (10), 1853-1857. doi: 10.5665/sleep.6168

Genetic correlation analysis suggests association between increased self-reported sleep duration in adults and schizophrenia and type 2 diabetes

2016

Journal Article

Across-cohort QC analyses of GWAS summary statistics from complex traits

Chen, Guo-Bo, Lee, Sang Hong, Robinson, Matthew R., Trzaskowski, Maciej, Zhu, Zhi-Xiang, Winkler, Thomas W., Day, Felix R., Croteau-Chonka, Damien C., Wood, Andrew R., Locke, Adam E., Kutalik, Zoltán, Loos, Ruth J. F., Frayling, Timothy M., Hirschhorn, Joel N., Yang, Jian, Wray, Naomi R. and Visscher, Peter M. (2016). Across-cohort QC analyses of GWAS summary statistics from complex traits. European Journal of Human Genetics, 25 (1), 137-146. doi: 10.1038/ejhg.2016.106

Across-cohort QC analyses of GWAS summary statistics from complex traits

2016

Journal Article

Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

Okbay, Aysu, Baselmans, Bart M. L., De Neve, Jan-Emmanuel, Turley, Patrick, Nivard, Michel G., Fontana, Mark Alan, Meddens, S. Fleur W., Linner, Richard Karlsson, Rietveld, Cornelius A., Derringer, Jaime, Gratten, Jacob, Lee, James J., Liu, Jimmy Z., de Vlaming, Ronald, Ahluwalia, Tarunveer S., Buchwald, Jadwiga, Cavadino, Alana, Frazier-Wood, Alexis C., Furlotte, Nicholas A., Garfield, Victoria, Geisel, Marie Henrike, Gonzalez, Juan R., Haitjema, Saskia, Karlsson, Robert, van der Laan, Sander W., Ladwig, Karl-Heinz, Lahti, Jari, van der Lee, Sven J., Lind, Penelope A. ... Cesarini, David (2016). Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nature Genetics, 48 (6), 624-633. doi: 10.1038/ng.3552

Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

2016

Journal Article

Application of linear mixed models to study genetic stability of height and body mass index across countries and time

Trzaskowski, Maciej, Lichtenstein, Paul, Magnusson, Patrik K., Pedersen, Nancy L. and Plomin, Robert (2016). Application of linear mixed models to study genetic stability of height and body mass index across countries and time. International Journal of Epidemiology, 45 (2), 417-423. doi: 10.1093/ije/dyv355

Application of linear mixed models to study genetic stability of height and body mass index across countries and time

2016

Conference Publication

Exploring heterogeneity in major depression

Mehta, Divya, Trzaskowski, Maciej, Maier, Robert and Wray, Naomi (2016). Exploring heterogeneity in major depression. 46th Annual Meeting of the Behavior-Genetics-Association, Brisbane Australia, Jun 20-23, 2016. New York, United States: Springer.

Exploring heterogeneity in major depression

2016

Conference Publication

Genetic influence on educational attainment and occupational status during and after the Soviet era in Estonia

Rimfeld, Kaili, Trzaskowski, Maciej, Esko, Tonu, Metspalu, Andres and Plomin, Robert (2016). Genetic influence on educational attainment and occupational status during and after the Soviet era in Estonia. 46th Annual Meeting of the Behavior-Genetics-Association, Brisbane Australia, 20-23 June 2016. New York, NY United States: Springer.

Genetic influence on educational attainment and occupational status during and after the Soviet era in Estonia

2015

Journal Article

Discontinuity in the genetic and environmental causes of the intellectual disability spectrum

Reichenberg, Abraham, Cederlöf, Martin, McMillan, Andrew, Trzaskowski, Maciej, Kapara, Ori, Fruchter, Eyal, Ginat, Karen, Davidson, Michael, Weiser, Mark, Larsson, Henrik, Plomin, Robert and Lichtenstein, Paul (2015). Discontinuity in the genetic and environmental causes of the intellectual disability spectrum. Proceedings of the National Academy of Sciences of the United States of America, 113 (4), 1098-1103. doi: 10.1073/pnas.1508093112

Discontinuity in the genetic and environmental causes of the intellectual disability spectrum

2015

Journal Article

Generalised anxiety disorder - a twin study of genetic architecture, genome-wide association and differential gene expression

Davies, Matthew N., Verdi, Serena, Burri, Andrea, Trzaskowski, Maciej, Lee, Minyoung, Hettema, John M., Jansen, Rick, Boomsma, Dorret I. and Spector, Tim D. (2015). Generalised anxiety disorder - a twin study of genetic architecture, genome-wide association and differential gene expression. PLoS ONE, 10 (8) e0134865, e0134865. doi: 10.1371/journal.pone.0134865

Generalised anxiety disorder - a twin study of genetic architecture, genome-wide association and differential gene expression

2015

Journal Article

Mosaic structural variation in children with developmental disorders

King, Daniel A., Jones, Wendy D., Crow, Yanick J., Dominiczak, Anna F., Foster, Nicola A., Gaunt, Tom R., Harris, Jade, Hellens, Stephen W., Homfray, Tessa, Innes, Josie, Jones, Elizabeth A., Joss, Shelagh, Kulkarni, Abhijit, Mansour, Sahar, Andrew D. Morris, D. Morris, Parker, Michael J., Porteous, David J., Shihab, Hashem A., Smith, Blair H., Tatton-Brown, Katrina, Tolmie, John L., Trzaskowski, Maciej, Vasudevan, Pradeep C., Wakeling, Emma, Wright, Michael, Plomin, Robert, Timpson, Nicholas J. and Hurles, Matthew E. (2015). Mosaic structural variation in children with developmental disorders. Human Molecular Genetics, 24 (10) ddv033, 2733-2745. doi: 10.1093/hmg/ddv033

Mosaic structural variation in children with developmental disorders

Current funding

  • 2025 - 2026
    Revolutionising disease gene discovery and risk prediction for glaucoma: an AI-driven approach utilising eye imaging and omics data (NHMRC Ideas Grant led by QIMR)
    Queensland Institute of Medical Research
    Open grant

Availability

Dr Maciej Trzaskowski is:
Available for supervision

Looking for a supervisor? Read our advice on how to choose a supervisor.

Supervision history

Current supervision

  • Doctor Philosophy

    Harness artificial intelligence to predict glaucoma risk using eye imaging and genetic data

    Associate Advisor

  • Doctor Philosophy

    Interpretable AI-Theory and Practice

    Associate Advisor

    Other advisors: Dr Quan Nguyen, Professor Fred Roosta

Completed supervision

Enquiries

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