Dr Niwanthi Rajapakse
Dr

Niwanthi Rajapakse

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Phone: 
+61 7 336 52402

Availability

Dr Niwanthi Rajapakse is:
Available for supervision
Media expert

Qualifications

  • Bachelor (Honours), Monash University
  • Doctor of Philosophy, Monash University

Search Professor Niwanthi Rajapakse’s works on UQ eSpace

48 works between 2002 and 2023
All (48) Journal Article (45) Conference Publication (3)

1 - 20 of 48 works

2023

Journal Article

SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein

Albornoz, Eduardo A., Amarilla, Alberto A., Modhiran, Naphak, Parker, Sandra, Li, Xaria X., Wijesundara, Danushka K., Aguado, Julio, Zamora, Adriana Pliego, McMillan, Christopher L. D., Liang, Benjamin, Peng, Nias Y. G., Sng, Julian D. J., Saima, Fatema Tuj, Fung, Jenny N., Lee, John D., Paramitha, Devina, Parry, Rhys, Avumegah, Michael S., Isaacs, Ariel, Lo, Martin W., Miranda-Chacon, Zaray, Bradshaw, Daniella, Salinas-Rebolledo, Constanza, Rajapakse, Niwanthi W., Wolvetang, Ernst J., Munro, Trent P., Rojas-Fernandez, Alejandro, Young, Paul R., Stacey, Katryn J. ... Woodruff, Trent M. (2023). SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein. Molecular Psychiatry, 28 (7), 2878-2893. doi: 10.1038/s41380-022-01831-0

SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein

2022

Journal Article

Stimulation of angiotensin converting enzyme 2: A novel treatment strategy for diabetic nephropathy

Nomura, Haru, Kuruppu, Sanjaya and Rajapakse, Niwanthi W. (2022). Stimulation of angiotensin converting enzyme 2: A novel treatment strategy for diabetic nephropathy. Frontiers in Physiology, 12 813012, 813012. doi: 10.3389/fphys.2021.813012

Stimulation of angiotensin converting enzyme 2: A novel treatment strategy for diabetic nephropathy

2022

Journal Article

Chronic renin-angiotensin system activation induced neuroinflammation: common mechanisms underlying hypertension and dementia?

Tran, Shirley, Kuruppu, Sanjaya and Rajapakse, Niwanthi W. (2022). Chronic renin-angiotensin system activation induced neuroinflammation: common mechanisms underlying hypertension and dementia?. Journal of Alzheimer's Disease, 85 (3), 943-955. doi: 10.3233/JAD-215231

Chronic renin-angiotensin system activation induced neuroinflammation: common mechanisms underlying hypertension and dementia?

2021

Conference Publication

Stimulating the Activity of NEP and ACE2: A Unique Approach to Prevent Dementia

Tran, Shirley, Woodruff, Trent, Kumar, Vinod, Smith, A. Ian, Rajapakse, Niwanthi and Kuruppu, Sanjaya (2021). Stimulating the Activity of NEP and ACE2: A Unique Approach to Prevent Dementia. Experimental Biology Meeting EB 2021, Online, 27–30 April 2022. Hoboken, NJ United States: John Wiley & Sons. doi: 10.1096/fasebj.2021.35.s1.01628

Stimulating the Activity of NEP and ACE2: A Unique Approach to Prevent Dementia

2020

Journal Article

Endothelial-specific overexpression of cationic amino acid transporter-1 prevents loss of kidney function in heart failure

Giam, Beverly, Nomura, Haru, Kuruppu, Sanjaya, Chu, Po-Yin, Essid, Sumia, Kiriazis, Helen, Du, Xiao-Jun, Kaye, David M. and Rajapakse, Niwanthi W. (2020). Endothelial-specific overexpression of cationic amino acid transporter-1 prevents loss of kidney function in heart failure. Clinical Science, 134 (20), 2755-2769. doi: 10.1042/CS20200087

Endothelial-specific overexpression of cationic amino acid transporter-1 prevents loss of kidney function in heart failure

2019

Journal Article

Impaired L-arginine-nitric oxide pathway contributes to the pathogenesis of resistant hypertension

Rajapakse, Niwanthi W., Giam, Beverly, Kuruppu, Sanjaya, Head, Geoffrey A. and Kaye, David M. (2019). Impaired L-arginine-nitric oxide pathway contributes to the pathogenesis of resistant hypertension. Clinical Science, 133 (20), 2061-2067. doi: 10.1042/CS20190851

Impaired L-arginine-nitric oxide pathway contributes to the pathogenesis of resistant hypertension

2018

Journal Article

Serelaxin attenuates renal inflammation and fibrosis in a mouse model of dilated cardiomyopathy

Giam, Beverly, Chu, Po-Yin, Kuruppu, Sanjaya, Smith, A. Ian, Horlock, Duncan, Murali, Aishwarya, Kiriazis, Helen, Du, Xiao-Jun, Kaye, David M. and Rajapakse, Niwanthi W. (2018). Serelaxin attenuates renal inflammation and fibrosis in a mouse model of dilated cardiomyopathy. Experimental Physiology, 103 (12), 1593-1602. doi: 10.1113/EP087189

Serelaxin attenuates renal inflammation and fibrosis in a mouse model of dilated cardiomyopathy

2017

Journal Article

N-Acetylcysteine Attenuates the Development of Renal Fibrosis in Transgenic Mice with Dilated Cardiomyopathy

Giam, Beverly, Kuruppu, Sanjaya, Chu, Po-Yin, Smith, A. Ian, Marques, Francine Z., Fiedler, April, Horlock, Duncan, Kiriazis, Helen, Du, Xiao-Jun, Kaye, David M. and Rajapakse, Niwanthi W. (2017). N-Acetylcysteine Attenuates the Development of Renal Fibrosis in Transgenic Mice with Dilated Cardiomyopathy. Scientific Reports, 7 (1) 17718, 1-12. doi: 10.1038/s41598-017-17927-5

N-Acetylcysteine Attenuates the Development of Renal Fibrosis in Transgenic Mice with Dilated Cardiomyopathy

2017

Journal Article

High fibre diet and acetate supplementation change the gut microbiota and prevent the development of hypertension and heart failure in hypertensive mice

Marques, Francine Z., Nelson, Erin, Chu, Po-Yin, Horlock, Duncan, Fiedler, April, Ziemann, Mark, Tan, Jian K., Kuruppu, Sanjaya, Rajapakse, Niwanthi W., El-Osta, Assam, Mackay, Charles R. and Kaye, David M. (2017). High fibre diet and acetate supplementation change the gut microbiota and prevent the development of hypertension and heart failure in hypertensive mice. Circulation, 135 (10), 964-977. doi: 10.1161/CIRCULATIONAHA.116.024545

High fibre diet and acetate supplementation change the gut microbiota and prevent the development of hypertension and heart failure in hypertensive mice

2017

Journal Article

The cardiovascular and neurotoxic effects of the venoms of six bony and cartilaginous fish species

Han, Han, Baumann, Kate, Casewell, Nicholas R., Ali, Syed A., Dobson, James, Koludarov, Ivan, Debono, Jordan, Cutmore, Scott C., Rajapakse, Niwanthi W., Jackson, Timothy N. W., Jones, Rob, Hodgson, Wayne C., Fry, Bryan G. and Kuruppu, Sanjaya (2017). The cardiovascular and neurotoxic effects of the venoms of six bony and cartilaginous fish species. Toxins, 9 (2) 67, 67. doi: 10.3390/toxins9020067

The cardiovascular and neurotoxic effects of the venoms of six bony and cartilaginous fish species

2017

Journal Article

The characteristics of astrocyte on Aβ clearance altered in Alzheimer’s disease were reversed by anti-inflammatory agent (+)-2-(1-hydroxyl-4-oxocyclohexyl) ethyl caffeate

Kuruppu, Sanjaya, Rajapakse, Niwanthi W., Parkington, Helena C. and Smith, A. Ian (2017). The characteristics of astrocyte on Aβ clearance altered in Alzheimer’s disease were reversed by anti-inflammatory agent (+)-2-(1-hydroxyl-4-oxocyclohexyl) ethyl caffeate. American Journal of Translational Research, 9 (7), 3514-3516.

The characteristics of astrocyte on Aβ clearance altered in Alzheimer’s disease were reversed by anti-inflammatory agent (+)-2-(1-hydroxyl-4-oxocyclohexyl) ethyl caffeate

2016

Journal Article

Stimulating the activity of amyloid-beta degrading enzymes: a novel approach for the therapeutic manipulation of amyloid-beta levels

Kuruppu, Sanjaya, Rajapakse, Niwanthi W., Spicer, Alexander J., Parkington, Helena C. and Smith, A. Ian (2016). Stimulating the activity of amyloid-beta degrading enzymes: a novel approach for the therapeutic manipulation of amyloid-beta levels. Journal of Alzheimers Disease, 54 (3), 891-895. doi: 10.3233/JAD-160492

Stimulating the activity of amyloid-beta degrading enzymes: a novel approach for the therapeutic manipulation of amyloid-beta levels

2016

Journal Article

Role of renal oxidative stress in the pathogenesis of the cardiorenal syndrome

Giam, Beverly, Kaye, David M. and Rajapakse, Niwanthi W. (2016). Role of renal oxidative stress in the pathogenesis of the cardiorenal syndrome. Heart, Lung and Circulation, 25 (8), 874-880. doi: 10.1016/j.hlc.2016.02.022

Role of renal oxidative stress in the pathogenesis of the cardiorenal syndrome

2016

Journal Article

Letter by Rajapakse et al regarding article, "Combined angiotensin receptor antagonism and neprilysin inhibition"

Rajapakse, Niwanthi W., Kuruppu, Sanjaya and Smith, A. Ian (2016). Letter by Rajapakse et al regarding article, "Combined angiotensin receptor antagonism and neprilysin inhibition". Circulation, 134 (3), E9-E10. doi: 10.1161/CIRCULATIONAHA.116.023086

Letter by Rajapakse et al regarding article, "Combined angiotensin receptor antagonism and neprilysin inhibition"

2016

Journal Article

Canopy venom: proteomic comparison among new world arboreal pit-viper venoms

Debono, Jordan, Cochran, Chip, Kuruppu, Sanjaya, Nouwens, Amanda, Rajapakse, Niwanthi W., Kawasaki, Minami, Wood, Kelly, Dobson, James, Baumann, Kate, Jouiaei, Mahdokht, Jackson, Timothy N. W., Koludarov, Ivan, Low, Dolyce, Ali, Syed A., Smith, A. Ian, Barnes, Andrew and Fry, Bryan G. (2016). Canopy venom: proteomic comparison among new world arboreal pit-viper venoms. Toxins, 8 (7) 210, 210.1-210.19. doi: 10.3390/toxins8070210

Canopy venom: proteomic comparison among new world arboreal pit-viper venoms

2016

Journal Article

Effects of dietary L-arginine on nitric oxide bioavailability in obese normotensive and obese hypertensive subjects

Giam, Beverly, Kuruppu, Sanjaya, Head, Geoffrey A., Kaye, David M. and Rajapakse, Niwanthi W. (2016). Effects of dietary L-arginine on nitric oxide bioavailability in obese normotensive and obese hypertensive subjects. Nutrients, 8 (6) 364, 364. doi: 10.3390/nu8060364

Effects of dietary L-arginine on nitric oxide bioavailability in obese normotensive and obese hypertensive subjects

2016

Journal Article

Say NO to obesity-related hypertension: role of the l-arginine-nitric oxide pathway

Rajapakse, Niwanthi W., Head, Geoffrey A. and Kaye, David M. (2016). Say NO to obesity-related hypertension: role of the l-arginine-nitric oxide pathway. Hypertension, 67 (5), 813-819. doi: 10.1161/HYPERTENSIONAHA.116.06778

Say NO to obesity-related hypertension: role of the l-arginine-nitric oxide pathway

2016

Journal Article

N-acetylcysteine attenuates the development of cardiac fibrosis and remodeling in a mouse model of heart failure

Giam, Beverly, Chu, Po-Yin, Kuruppu, Sanjaya, Smith, A. Ian, Horlock, Duncan, Kiriazis, Helen, Du, Xiao-Jun, Kaye, David M. and Rajapakse, Niwanthi W. (2016). N-acetylcysteine attenuates the development of cardiac fibrosis and remodeling in a mouse model of heart failure. Physiological Reports, 4 (7), 1-13. doi: 10.14814/phy2.12757

N-acetylcysteine attenuates the development of cardiac fibrosis and remodeling in a mouse model of heart failure

2016

Conference Publication

N‐acetylcysteine reverses established cardiac and renal fibrosis in a mouse model of heart failure

Rajapakse, Niwanthi, Giam, Beverly, Chu, Po‐Yin, Kiriazis, Helen, Du, Xiao‐Jun and Kaye, David M. (2016). N‐acetylcysteine reverses established cardiac and renal fibrosis in a mouse model of heart failure. Experimental Biology 2016 Meeting, San Diego, CA United States, 1-5 April 2016. Hoboken, NJ United States: John Wiley & Sons. doi: 10.1096/fasebj.30.1_supplement.735.4

N‐acetylcysteine reverses established cardiac and renal fibrosis in a mouse model of heart failure

2016

Conference Publication

N‐terminal domain of Bothrops asper Myotoxin II Enhances the Activity of Endothelin Converting Enzyme and Neprilysin

Kuruppu, Sanjaya, Rajapakse, Niwanthi, Kleifeld, Oded, Small, David H., Whisstock, James and Smith, Alexander Ian (2016). N‐terminal domain of Bothrops asper Myotoxin II Enhances the Activity of Endothelin Converting Enzyme and Neprilysin. Experimental Biology 2016 Meeting, San Diego, CA United States, 1-5 April 2016. Hoboken, NJ United States: John Wiley & Sons. doi: 10.1096/fasebj.30.1_supplement.606.4

N‐terminal domain of Bothrops asper Myotoxin II Enhances the Activity of Endothelin Converting Enzyme and Neprilysin

Past funding

  • 2019
    Vevo 3100 Imaging System for ultrahigh resolution and frame rate echocardiographic assessment of small animals.
    UQ Major Equipment and Infrastructure
    Open grant

Availability

Dr Niwanthi Rajapakse is:
Available for supervision

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Supervision history

Completed supervision

Enquiries

Contact Dr Niwanthi Rajapakse directly for media enquiries about:

  • cardiorenal disease
  • cardiovascular disease
  • heart failure
  • Kidney disease
  • kidney failure
  • nitric oxide

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