Dr Niwanthi Rajapakse
Dr

Niwanthi Rajapakse

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Phone: 
+61 7 336 52402

Availability

Dr Niwanthi Rajapakse is:
Available for supervision
Media expert

Qualifications

  • Bachelor (Honours), Monash University
  • Doctor of Philosophy, Monash University

Search Professor Niwanthi Rajapakse’s works on UQ eSpace

51 works between 2002 and 2024
All (51) Journal Article (48) Conference Publication (3)

21 - 40 of 51 works

2016

Journal Article

N-acetylcysteine attenuates the development of cardiac fibrosis and remodeling in a mouse model of heart failure

Giam, Beverly, Chu, Po-Yin, Kuruppu, Sanjaya, Smith, A. Ian, Horlock, Duncan, Kiriazis, Helen, Du, Xiao-Jun, Kaye, David M. and Rajapakse, Niwanthi W. (2016). N-acetylcysteine attenuates the development of cardiac fibrosis and remodeling in a mouse model of heart failure. Physiological Reports, 4 (7), 1-13. doi: 10.14814/phy2.12757

N-acetylcysteine attenuates the development of cardiac fibrosis and remodeling in a mouse model of heart failure

2016

Conference Publication

N‐terminal domain of Bothrops asper Myotoxin II Enhances the Activity of Endothelin Converting Enzyme and Neprilysin

Kuruppu, Sanjaya, Rajapakse, Niwanthi, Kleifeld, Oded, Small, David H., Whisstock, James and Smith, Alexander Ian (2016). N‐terminal domain of Bothrops asper Myotoxin II Enhances the Activity of Endothelin Converting Enzyme and Neprilysin. Experimental Biology 2016 Meeting, San Diego, CA United States, 1-5 April 2016. Hoboken, NJ United States: John Wiley & Sons. doi: 10.1096/fasebj.30.1_supplement.606.4

N‐terminal domain of Bothrops asper Myotoxin II Enhances the Activity of Endothelin Converting Enzyme and Neprilysin

2016

Conference Publication

N‐acetylcysteine reverses established cardiac and renal fibrosis in a mouse model of heart failure

Rajapakse, Niwanthi, Giam, Beverly, Chu, Po‐Yin, Kiriazis, Helen, Du, Xiao‐Jun and Kaye, David M. (2016). N‐acetylcysteine reverses established cardiac and renal fibrosis in a mouse model of heart failure. Experimental Biology 2016 Meeting, San Diego, CA United States, 1-5 April 2016. Hoboken, NJ United States: John Wiley & Sons. doi: 10.1096/fasebj.30.1_supplement.735.4

N‐acetylcysteine reverses established cardiac and renal fibrosis in a mouse model of heart failure

2016

Journal Article

N-terminal domain of Bothrops asper Myotoxin II Enhances the Activity of Endothelin Converting Enzyme-1 and Neprilysin

Smith, A. Ian, Rajapakse, Niwanthi W., Kleifeld, Oded, Lomonte, Bruno, Sikanyika, Nkumbu L., Spicer, Alexander J., Hodgson, Wayne C., Conroy, Paul J., Small, David H., Kaye, David M., Parkington, Helena C., Whisstock, James C. and Kuruppu, Sanjaya (2016). N-terminal domain of Bothrops asper Myotoxin II Enhances the Activity of Endothelin Converting Enzyme-1 and Neprilysin. Scientific Reports, 6 (1) 22413, 22413.1-22413.11. doi: 10.1038/srep22413

N-terminal domain of Bothrops asper Myotoxin II Enhances the Activity of Endothelin Converting Enzyme-1 and Neprilysin

2015

Journal Article

Cardio-protective effects of combined l-arginine and insulin: mechanism and therapeutic actions in myocardial ischemia-reperfusion injury

Venardos, Kylie M., Rajapakse, Niwanthi W., Williams, David, Hoe, Louise S., Peart, Jason N. and Kaye, David M. (2015). Cardio-protective effects of combined l-arginine and insulin: mechanism and therapeutic actions in myocardial ischemia-reperfusion injury. European Journal of Pharmacology, 769, 64-70. doi: 10.1016/j.ejphar.2015.09.046

Cardio-protective effects of combined l-arginine and insulin: mechanism and therapeutic actions in myocardial ischemia-reperfusion injury

2015

Journal Article

Pathogenesis and treatment of the cardiorenal syndrome: implications of L-arginine-nitric oxide pathway impairment

Rajapakse, Niwanthi W., Nanayakkara, Shane and Kaye, David M. (2015). Pathogenesis and treatment of the cardiorenal syndrome: implications of L-arginine-nitric oxide pathway impairment. Pharmacology & Therapeutics, 154, 1-12. doi: 10.1016/j.pharmthera.2015.05.011

Pathogenesis and treatment of the cardiorenal syndrome: implications of L-arginine-nitric oxide pathway impairment

2015

Journal Article

Augmented endothelial-specific L-arginine transport blunts the contribution of the sympathetic nervous system to obesity induced hypertension in mice

Rajapakse, Niwanthi W., Karim, Florian, Evans, Roger G., Kaye, David M. and Head, Geoffrey A. (2015). Augmented endothelial-specific L-arginine transport blunts the contribution of the sympathetic nervous system to obesity induced hypertension in mice. Plos One, 10 (7) e0131424, e0131424. doi: 10.1371/journal.pone.0131424

Augmented endothelial-specific L-arginine transport blunts the contribution of the sympathetic nervous system to obesity induced hypertension in mice

2015

Journal Article

Augmented endothelial l-arginine transport ameliorates pressure-overload-induced cardiac hypertrophy

Rajapakse, Niwanthi W., Johnston, Tamara, Kiriazis, Helen, Chin-Dusting, Jaye P., Du, Xiao-Jun and Kaye, David M. (2015). Augmented endothelial l-arginine transport ameliorates pressure-overload-induced cardiac hypertrophy. Experimental Physiology, 100 (7), 796-804. doi: 10.1113/EP085250

Augmented endothelial l-arginine transport ameliorates pressure-overload-induced cardiac hypertrophy

2014

Journal Article

Endothelial cationic amino acid transporter-1 overexpression blunts the effects of oxidative stress on pressor responses to behavioural stress in mice

Rajapakse, Niwanthi W., Konstantinidis, George, Evans, Roger G., Nguyen-Huu, Thu-Phuc, Kaye, David M. and Head, Geoffrey A. (2014). Endothelial cationic amino acid transporter-1 overexpression blunts the effects of oxidative stress on pressor responses to behavioural stress in mice. Clinical and Experimental Pharmacology and Physiology, 41 (12), 1031-1037. doi: 10.1111/1440-1681.12279

Endothelial cationic amino acid transporter-1 overexpression blunts the effects of oxidative stress on pressor responses to behavioural stress in mice

2014

Journal Article

Nitric oxide inhibits the production of soluble endothelin converting enzyme-1

Kuruppu, Sanjaya, Rajapakse, Niwanthi W., Dunstan, Rhys A. and Smith, A. Ian (2014). Nitric oxide inhibits the production of soluble endothelin converting enzyme-1. Molecular and Cellular Biochemistry, 396 (1-2), 49-54. doi: 10.1007/s11010-014-2141-0

Nitric oxide inhibits the production of soluble endothelin converting enzyme-1

2014

Journal Article

Augmented endothelial-specific L-arginine transport prevents obesity-induced hypertension

Rajapakse, N. W., Karim, F., Straznicky, N. E., Fernandez, S., Evans, R. G., Head, G. A. and Kaye, D. M. (2014). Augmented endothelial-specific L-arginine transport prevents obesity-induced hypertension. Acta Physiologica, 212 (1), 39-48. doi: 10.1111/apha.12344

Augmented endothelial-specific L-arginine transport prevents obesity-induced hypertension

2014

Journal Article

Renal oxygenation in acute renal ischemia-reperfusion injury

Abdelkader, Amany, Ho, Julie, Ow, Connie P. C., Eppel, Gabriela A., Rajapakse, Niwanthi W., Schlaich, Markus P. and Evans, Roger G. (2014). Renal oxygenation in acute renal ischemia-reperfusion injury. American Journal of Physiology-Renal Physiology, 306 (9), F1026-F1038. doi: 10.1152/ajprenal.00281.2013

Renal oxygenation in acute renal ischemia-reperfusion injury

2014

Journal Article

Production of soluble Neprilysin by endothelial cells

Kuruppu, Sanjaya, Rajapakse, Niwanthi W., Minond, Dmitriy and Smith, A. Ian (2014). Production of soluble Neprilysin by endothelial cells. Biochemical and Biophysical Research Communications, 446 (2), 423-427. doi: 10.1016/j.bbrc.2014.01.158

Production of soluble Neprilysin by endothelial cells

2014

Journal Article

Endothelial cationic amino acid transporter-1 overexpression can prevent oxidative stress and increases in arterial pressure in response to superoxide dismutase inhibition in mice

Konstantinidis, G., Head, G. A., Evans, R. G., Nguyen-Huu, T. -P., Venardos, K., Croft, K. D., Mori, T. A., Kaye, D. M. and Rajapakse, N. W. (2014). Endothelial cationic amino acid transporter-1 overexpression can prevent oxidative stress and increases in arterial pressure in response to superoxide dismutase inhibition in mice. Acta Physiologica, 210 (4), 845-853. doi: 10.1111/apha.12215

Endothelial cationic amino acid transporter-1 overexpression can prevent oxidative stress and increases in arterial pressure in response to superoxide dismutase inhibition in mice

2013

Journal Article

Endothelin-converting enzyme-1 inhibition and renoprotection in end-stage renal disease

Kuruppu, Sanjaya, Rajapakse, Niwanthi W. and Smith, A. Ian (2013). Endothelin-converting enzyme-1 inhibition and renoprotection in end-stage renal disease. Pflugers Archiv - European Journal of Physiology, 465 (7), 929-934. doi: 10.1007/s00424-013-1216-1

Endothelin-converting enzyme-1 inhibition and renoprotection in end-stage renal disease

2013

Journal Article

Insulin-mediated activation of the L-arginine nitric oxide pathway in man, and its impairment in diabetes

Rajapakse, Niwanthi W., Chong, Abigail L., Zhang, Wei-Zheng and Kaye, David M. (2013). Insulin-mediated activation of the L-arginine nitric oxide pathway in man, and its impairment in diabetes. Plos One, 8 (5) e61840, e61840. doi: 10.1371/journal.pone.0061840

Insulin-mediated activation of the L-arginine nitric oxide pathway in man, and its impairment in diabetes

2013

Journal Article

Role of cellular L-arginine uptake and nitric oxide production on renal blood flow and arterial pressure regulation

Rajapakse, Niwanthi W. and Mattson, David L. (2013). Role of cellular L-arginine uptake and nitric oxide production on renal blood flow and arterial pressure regulation. Current Opinion in Nephrology and Hypertension, 22 (1), 45-50. doi: 10.1097/MNH.0b013e32835a6ff7

Role of cellular L-arginine uptake and nitric oxide production on renal blood flow and arterial pressure regulation

2012

Journal Article

Evidence that renal arginine transport is impaired in spontaneously hypertensive rats

Rajapakse, N. W., Kuruppu, S., Hanchapola, I., Venardos, K., Mattson, D. L., Smith, A. I., Kaye, D. M. and Evans, R. G. (2012). Evidence that renal arginine transport is impaired in spontaneously hypertensive rats. American Journal of Physiology-Renal Physiology, 302 (12), F1554-F1562. doi: 10.1152/ajprenal.00084.2011

Evidence that renal arginine transport is impaired in spontaneously hypertensive rats

2011

Journal Article

Role of l-arginine uptake mechanisms in renal blood flow responses to angiotensin II in rats

Rajapakse, N. W. and Mattson, D. L. (2011). Role of l-arginine uptake mechanisms in renal blood flow responses to angiotensin II in rats. Acta Physiologica, 203 (3), 391-400. doi: 10.1111/j.1748-1716.2011.02330.x

Role of l-arginine uptake mechanisms in renal blood flow responses to angiotensin II in rats

2010

Journal Article

Angiotensin II and neurohumoral control of the renal medullary circulation

Evans, Roger G., Head, Geoffrey A., Eppel, Gabriela A., Burke, Sandra L. and Rajapakse, Niwanthi W. (2010). Angiotensin II and neurohumoral control of the renal medullary circulation. Clinical and Experimental Pharmacology and Physiology, 37 (2), E58-E69. doi: 10.1111/j.1440-1681.2009.05233.x

Angiotensin II and neurohumoral control of the renal medullary circulation

Past funding

  • 2019
    Vevo 3100 Imaging System for ultrahigh resolution and frame rate echocardiographic assessment of small animals.
    UQ Major Equipment and Infrastructure
    Open grant

Availability

Dr Niwanthi Rajapakse is:
Available for supervision

Before you email them, read our advice on how to contact a supervisor.

Supervision history

Completed supervision

Enquiries

Contact Dr Niwanthi Rajapakse directly for media enquiries about:

  • cardiorenal disease
  • cardiovascular disease
  • heart failure
  • Kidney disease
  • kidney failure
  • nitric oxide

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