Overview
Availability
- Dr Alexis de Sa Ribeiro Do Bonfim Melo is:
- Available for supervision
Qualifications
- Doctor of Philosophy of Biological Sciences, Universidade Federal de São Paulo (Unifesp)
Works
Search Professor Alexis de Sa Ribeiro Do Bonfim Melo’s works on UQ eSpace
2024
Journal Article
Aurora B inhibitors promote RB hypophosphorylation and senescence independent of p53-dependent CDK2/4 inhibition
Vora, Shivam, Andrew, Ariel, Kumar, Ramyashree Prasanna, Nazareth, Deborah, Bonfim-Melo, Alexis, Lim, Yoon, Ong, Xin Yee, Fernando, Madushan, He, Yaowu, Hooper, John D., McMillan, Nigel A. J., Urosevic, Jelena, Travers, Jon, Saeh, Jamal, Kumar, Sharad, Jones, Mathew J. K. and Gabrielli, Brian (2024). Aurora B inhibitors promote RB hypophosphorylation and senescence independent of p53-dependent CDK2/4 inhibition. Cell Death & Disease, 15 (11) 810, 810. doi: 10.1038/s41419-024-07204-5
2024
Journal Article
PPTC7 antagonizes mitophagy by promoting BNIP3 and NIX degradation via SCFFBXL4
Nguyen-Dien, Giang Thanh, Townsend, Brendan, Kulkarni, Prajakta Gosavi, Kozul, Keri-Lyn, Ooi, Soo Siang, Eldershaw, Denaye N, Weeratunga, Saroja, Liu, Meihan, Jones, Mathew JK, Millard, S Sean, Ng, Dominic CH, Pagano, Michele, Bonfim-Melo, Alexis, Schneider, Tobias, Komander, David, Lazarou, Michael, Collins, Brett M and Pagan, Julia K (2024). PPTC7 antagonizes mitophagy by promoting BNIP3 and NIX degradation via SCFFBXL4. EMBO Reports, 25 (8), 3324-3347. doi: 10.1038/s44319-024-00181-y
2024
Journal Article
TGF-β signalling limits effector function capacity of NK cell anti-tumour immunity in human bladder cancer
Wong, Joshua K. M., McCulloch, Timothy R., Alim, Louisa, Omer, Natacha, Mehdi, Ahmed M., Tuong, Zewen Kelvin, Bonfim-Melo, Alexis, Chung, Eric, Nicol, Alice, Simpson, Fiona, Rhee, Handoo, Rossi, Gustavo Rodrigues and Souza-Fonseca-Guimaraes, Fernando (2024). TGF-β signalling limits effector function capacity of NK cell anti-tumour immunity in human bladder cancer. EBioMedicine, 104 105176. doi: 10.1016/j.ebiom.2024.105176
2023
Journal Article
An E-cadherin-actin clutch translates the mechanical force of cortical flow for cell-cell contact to inhibit epithelial cell locomotion
Noordstra, Ivar, Hermoso, Mario Díez, Schimmel, Lilian, Bonfim-Melo, Alexis, Currin-Ross, Denni, Duong, Cao Nguyen, Kalappurakkal, Joseph Mathew, Morris, Richard G., Vestweber, Dietmar, Mayor, Satyajit, Gordon, Emma, Roca-Cusachs, Pere and Yap, Alpha S. (2023). An E-cadherin-actin clutch translates the mechanical force of cortical flow for cell-cell contact to inhibit epithelial cell locomotion. Developmental Cell, 58 (18), 1748-1763.e6. doi: 10.1016/j.devcel.2023.06.011
2022
Journal Article
Successful invasion of Trypanosoma cruzi trypomastigotes is dependent on host cell actin cytoskeleton
Bonifácio, Bruno Souza, Bonfim‐Melo, Alexis, Mortara, Renato Arruda and Ferreira, Éden Ramalho (2022). Successful invasion of Trypanosoma cruzi trypomastigotes is dependent on host cell actin cytoskeleton. Journal of Eukaryotic Microbiology, 69 (3) e12903, e12903. doi: 10.1111/jeu.12903
2022
Journal Article
Rapid lamellipodial responses by neighbor cells drive epithelial sealing in response to pyroptotic cell death
Bonfim-Melo, Alexis, Noordstra, Ivar, Gupta, Shafali, Chan, Amy H., Jones, Mathew J.K., Schroder, Kate and Yap, Alpha S. (2022). Rapid lamellipodial responses by neighbor cells drive epithelial sealing in response to pyroptotic cell death. Cell Reports, 38 (5) 110316, 110316. doi: 10.1016/j.celrep.2022.110316
2022
Journal Article
Regulating life after death: how mechanical communication mediates the epithelial response to apoptosis
Bonfim-Melo, Alexis, Duszyc, Kinga, Gomez, Guillermo A. and Yap, Alpha S. (2022). Regulating life after death: how mechanical communication mediates the epithelial response to apoptosis. The European Physical Journal E, 45 (1) 9, 9. doi: 10.1140/epje/s10189-022-00163-9
2021
Journal Article
Trypanosoma cruzi extracellular amastigotes engage Rac1 and Cdc42 to invade RAW macrophages
Medina, Camila Macedo, Ferreira, Éden Ramalho, Bonifácio, Bruno Souza, Mortara, Renato Arruda and Bonfim-Melo, Alexis (2021). Trypanosoma cruzi extracellular amastigotes engage Rac1 and Cdc42 to invade RAW macrophages. Microbes and Infection, 23 (8) 104837, 104837. doi: 10.1016/j.micinf.2021.104837
2021
Journal Article
Parasite-mediated remodeling of the host microfilament cytoskeleton enables rapid egress of Trypanosoma cruzi following membrane rupture
Ferreira, Eden R., Bonfim-Melo, Alexis, Burleigh, Barbara A., Costales, Jaime A., Tyler, Kevin M. and Mortara, Renato A. (2021). Parasite-mediated remodeling of the host microfilament cytoskeleton enables rapid egress of Trypanosoma cruzi following membrane rupture. mBio, 12 (3) e00988-21. doi: 10.1128/mbio.00988-21
2020
Journal Article
Genomic properties and temporal analysis of the interaction of an invasive Escherichia albertii with epithelial cells
Romão, Fabiano T., Martins, Fernando H., Hernandes, Rodrigo T., Ooka, Tadasuke, Santos, Fernanda F., Yamamoto, Denise, Bonfim-Melo, Alexis, Jones, Nina, Hayashi, Tetsuya, Elias, Waldir P., Sperandio, Vanessa and Gomes, Tânia A. T. (2020). Genomic properties and temporal analysis of the interaction of an invasive Escherichia albertii with epithelial cells. Frontiers in Cellular and Infection Microbiology, 10 571088, 1-14. doi: 10.3389/fcimb.2020.571088
2019
Journal Article
Trypanosoma cruzi extracellular amastigotes selectively trigger the PI3K/Akt and Erk pathways during HeLa cell invasion
Ferreira, Bianca Lima, Ferreira, Éden Ramalho, Bonfim-Melo, Alexis, Mortara, Renato Arruda and Bahia, Diana (2019). Trypanosoma cruzi extracellular amastigotes selectively trigger the PI3K/Akt and Erk pathways during HeLa cell invasion. Microbes and Infection, 21 (10), 485-489. doi: 10.1016/j.micinf.2019.06.003
2019
Journal Article
Host cell protein LAMP‐2 is the receptor for Trypanosoma cruzi surface molecule gp82 that mediates invasion
Rodrigues, João Paulo Ferreira, Souza Onofre, Thiago, Barbosa, Bruno Couto, Ferreira, Éden Ramalho, Bonfim‐Melo, Alexis and Yoshida, Nobuko (2019). Host cell protein LAMP‐2 is the receptor for Trypanosoma cruzi surface molecule gp82 that mediates invasion. Cellular Microbiology, 21 (5) e13003, e13003. doi: 10.1111/cmi.13003
2018
Journal Article
Amastigote synapse: the tricks of Trypanosoma cruzi extracellular amastigotes
Bonfim-Melo, Alexis, Ferreira, Eden R., Florentino, Pilar T.V. and Mortara, Renato A. (2018). Amastigote synapse: the tricks of Trypanosoma cruzi extracellular amastigotes. Frontiers in Microbiology, 9 (JUN) 1341. doi: 10.3389/fmicb.2018.01341
2018
Journal Article
Rac1/WAVE2 and Cdc42/N-WASP participation in actin-dependent host cell invasion by extracellular amastigotes of Trypanosoma cruzi
Bonfim-Melo, Alexis, Ferreira, Éden R. and Mortara, Renato A. (2018). Rac1/WAVE2 and Cdc42/N-WASP participation in actin-dependent host cell invasion by extracellular amastigotes of Trypanosoma cruzi. Frontiers in Microbiology, 9 (FEB) 360, 360. doi: 10.3389/fmicb.2018.00360
2017
Journal Article
ERM proteins play distinct roles in cell invasion by extracellular amastigotes of Trypanosoma cruzi
Ferreira, Éden R., Bonfim-Melo, Alexis, Cordero, Esteban M. and Mortara, Renato A. (2017). ERM proteins play distinct roles in cell invasion by extracellular amastigotes of Trypanosoma cruzi. Frontiers in Microbiology, 8 (NOV) 2230, 2230. doi: 10.3389/fmicb.2017.02230
2017
Journal Article
Candida albicans: the ability to invade epithelial cells and survive under oxidative stress is unlinked to hyphal length
Maza, Paloma K., Bonfim-Melo, Alexis, Padovan, Ana C.B., Mortara, Renato A., Orikaza, Cristina M., Ramos, Lilian M. Damas, Moura, Tauany R., Soriani, Frederico M., Almeida, Ricardo S., Suzuki, Erika and Bahia, Diana (2017). Candida albicans: the ability to invade epithelial cells and survive under oxidative stress is unlinked to hyphal length. Frontiers in Microbiology, 8 (JUL) 1235, 1235. doi: 10.3389/fmicb.2017.01235
2016
Journal Article
Genetic relatedness and virulence properties of enteropathogenic Escherichia coli strains of serotype O119: H6 expressing localized adherence or localized and aggregative adherence-like patterns on HeLa cells
Garcia, Bruna G., Ooka, Tadasuke, Gotoh, Yasuhiro, Vieira, Mônica A.M., Yamamoto, Denise, Ogura, Yoshitoshi, Girão, Dennys M., Sampaio, Suely C.F., Melo, Alexis Bonfim, Irino, Kinue, Hayashi, Tetsuya and Gomes, Tânia A.T. (2016). Genetic relatedness and virulence properties of enteropathogenic Escherichia coli strains of serotype O119: H6 expressing localized adherence or localized and aggregative adherence-like patterns on HeLa cells. International Journal of Medical Microbiology, 306 (3), 152-164. doi: 10.1016/j.ijmm.2016.02.008
2016
Journal Article
Unique behavior of Trypanosoma cruzi mevalonate kinase: a conserved glycosomal enzyme involved in host cell invasion and signaling
Ferreira, Éden Ramalho, Horjales, Eduardo, Bonfim-Melo, Alexis, Cortez, Cristian, Da Silva, Claudio Vieira, De Groote, Michel, Sobreira, Tiago José Paschoal, Cruz, Mário Costa, Lima, Fabio Mitsuo, Cordero, Esteban Mauricio, Yoshida, Nobuko, Da Silveira, José Franco, Mortara, Renato Arruda and Bahia, Diana (2016). Unique behavior of Trypanosoma cruzi mevalonate kinase: a conserved glycosomal enzyme involved in host cell invasion and signaling. Scientific Reports, 6 (1) 24610. doi: 10.1038/srep24610
2015
Journal Article
Trypanosoma cruzi extracellular amastigotes trigger the protein kinase D1-cortactin-actin pathway during cell invasion
Bonfim-Melo, Alexis, Zanetti, Bianca Ferrarini, Ferreira, Éden Ramalho, Vandoninck, Sandy, Han, Sang Won, Van Lint, Johan, Mortara, Renato Arruda and Bahia, Diana (2015). Trypanosoma cruzi extracellular amastigotes trigger the protein kinase D1-cortactin-actin pathway during cell invasion. Cellular Microbiology, 17 (12), 1797-1810. doi: 10.1111/cmi.12472
2014
Journal Article
An historical perspective on how advances in microscopic imaging contributed to understanding the Leishmania Spp. and Trypanosoma cruzi host-parasite relationship
Florentino, P. T.V., Real, F., Bonfim-Melo, A., Orikaza, C. M., Ferreira, E. R., Pessoa, C. C., Lima, B. R., Sasso, G. R.S. and Mortara, R. A. (2014). An historical perspective on how advances in microscopic imaging contributed to understanding the Leishmania Spp. and Trypanosoma cruzi host-parasite relationship. BioMed Research International, 2014 565291, 1-16. doi: 10.1155/2014/565291
Supervision
Availability
- Dr Alexis de Sa Ribeiro Do Bonfim Melo is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Decoding the spatiotemporal control of DNA replication and repair
Associate Advisor
Other advisors: Professor Paul Clarke, Dr Mathew Jones
Media
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