![Associate Professor Lucy Burr](/sites/default/files/profiles/3504.jpeg)
Overview
Background
A/Prof Lucy Burr is an experienced respiratory physician, training supervisor and clinical trials researcher at Mater Health and Mater Research – University of Queensland (UQ). She has a PhD (2017) in bronchiectasis microbiology and is an Associate Professor at the School of Medicine, UQ. She is the Director of Respiratory, Sleep and Cystic Fibrosis medicine at the Mater Hospital, Brisbane.
As well as directing the respiratory clinical service at the Mater, Lucy has an active role in teaching both specialist trainees and medical students. She is a RACP college supervisor and trains one advanced trainee and four basic trainees per year. She directly supervises four medical students in her clinical team per year. Lucy is also currently supervising 5 PhD students, researching diverse fields such as glucose control in cystic fibrosis, asthma, fatigue, IL-22 and the effect of sleep on social cognition.
Lucy is recognised nationally for her clinical work on respiratory infections. She is the chair of the Acute and Critical Care panel for the National COVID-19 clinical evidence taskforce and a member of the guideline leadership group. Additionally, she is the recent chair (2020-2022) of the expert reference group on COVID-19 for the Royal Australasian College of Physicians. She is a recent (2019- 2021) convenor of the respiratory infectious disease special interest group of the Thoracic Society of Australia and New Zealand, the Queensland TSANZ branch president and past president (2017-2020), a recent board director of the TSANZ national body and current Chair of the Australian Bronchiectasis Consortium. Lucy is currently serving on the TSANZ annual scientific meeting and World Bronchiectasis conference steering committees. She is recognised internationally for her work on Cystic Fibrosis (top 1.8% expertscape February 2024) and Bronchiectasis (top 2.2% expertscape February 2024) and has published in high impact clinical journals including the New England Journal of Medicine and the Lancet Respiratory Medicine, across a range of respiratory and infectious disease subjects, with >1500 citations in the past 5 years.
In addition to her clinical work, Lucy is the custodian and manager of the David Serisier Research biobank at Mater Research, a clinical repository of human samples from patients living with respiratory diseases. Lucy is also an experienced principal investigator on many pharmaceutical studies ranging from phase 1b to phase 4 studies investigating therapeutics for CF, IPF, COPD, COVID, influenza pulmonary hypertension and bronchiectasis. She has designed and lead non-pharmaceutical interventional studies investigating the role of macrolide in modulating inflammation in healthy adults. She is the group leader of the respiratory clinical trials unit at Mater Research, and the program lead for the chronic and integrated care program at Mater Research.
Lucy has a proven track record in collaborative and translational research. She is currently a consultant on 2 peer reviewed external grants totalling $1,306,000, including one involving biobanked samples, and is a chief investigator on a 2021 Ideas grant and a 2021 MRFF grant totalling more than $3 million dollars.
Availability
- Associate Professor Lucy Burr is:
- Available for supervision
Fields of research
Qualifications
- Bachelor (Honours) of Medical Sciences, King's College London
- Bachelor of Medicine and Surgery and Medical Science, King's College London
- Doctor of Philosophy of Respiratory Diseases, The University of Queensland
- Diploma of Leadership and Management, unknown
- Fellow, Royal Australasian College of Physicians, Royal Australasian College of Physicians
- Fellow, Thoracic Society of Australia & New Zealand, Thoracic Society of Australia & New Zealand
Works
Search Professor Lucy Burr’s works on UQ eSpace
2024
Journal Article
Cloaking antibodies are prevalent in Burkholderia cepacia complex infection and their removal restores serum killing
Pham, Amy, Tan, Kellynn K. Y., Ledger, Emma L., Smith, Daniel J., Reid, David W., Burr, Lucy, Chambers, Daniel C. and Wells, Timothy J. (2024). Cloaking antibodies are prevalent in Burkholderia cepacia complex infection and their removal restores serum killing. Frontiers in Cellular and Infection Microbiology, 14 1426773. doi: 10.3389/fcimb.2024.1426773
2024
Journal Article
Current physiotherapy practice for adults with bronchiectasis: data from the Australian Bronchiectasis Registry
Webb, Elizabeth M., Holland, Anne E., Chang, Anne B., Burr, Lucy, Holmes-Liew, Chien-Li, King, Paul T., Middleton, Peter G., Morgan, Lucy, Thomson, Rachel M., Wong, Conroy and Lee, Annemarie L. (2024). Current physiotherapy practice for adults with bronchiectasis: data from the Australian Bronchiectasis Registry. Respiratory Medicine, 233 107777, 107777. doi: 10.1016/j.rmed.2024.107777
2024
Journal Article
Pancreatic beta-cell IL-22 receptor deficiency induces age-dependent dysregulation of insulin biosynthesis and systemic glucose homeostasis
Sajiir, Haressh, Wong, Kuan Yau, Müller, Alexandra, Keshvari, Sahar, Burr, Lucy, Aiello, Elena, Mezza, Teresa, Giaccari, Andrea, Sebastiani, Guido, Dotta, Francesco, Ramm, Grant A., Macdonald, Graeme A., McGuckin, Michael A., Prins, Johannes B. and Hasnain, Sumaira Z. (2024). Pancreatic beta-cell IL-22 receptor deficiency induces age-dependent dysregulation of insulin biosynthesis and systemic glucose homeostasis. Nature Communications, 15 (1) 4527, 4527. doi: 10.1038/s41467-024-48320-2
2024
Journal Article
Liver and pancreatic-targeted interleukin-22 as a therapeutic for metabolic dysfunction-associated steatohepatitis
Sajiir, Haressh, Keshvari, Sahar, Wong, Kuan Yau, Borg, Danielle J., Steyn, Frederik J., Fercher, Christian, Taylor, Karin, Taylor, Breten, Barnard, Ross T., Müller, Alexandra, Moniruzzaman, Md, Miller, Gregory, Wang, Ran, Fotheringham, Amelia, Schreiber, Veronika, Sheng, Yong Hua, Hancock, Janelle Louise, Loo, Dorothy, Burr, Lucy, Huynh, Tony, Lockett, Jack, Ramm, Grant A., Macdonald, Graeme A., Prins, Johannes B., McGuckin, Michael A. and Hasnain, Sumaira Z. (2024). Liver and pancreatic-targeted interleukin-22 as a therapeutic for metabolic dysfunction-associated steatohepatitis. Nature Communications, 15 (1) 4528, 4528. doi: 10.1038/s41467-024-48317-x
2024
Journal Article
Erdosteine in children and adults with bronchiectasis (BETTER trial): study protocol for a multicentre, double-blind, randomised controlled trial
Chang, Anne B., Yerkovich, Stephanie T., Baines, Katherine J., Burr, Lucy, Champion, Anita, Chatfield, Mark D., Eg, Kah P, Goyal, Vikas, Marsh, Robyn L, McCallum, Gabrielle B, McElrea, Margaret, McPhail, Steven, Morgan, Lucy C, Morris, Peter S, Nathan, Anne M, O’Farrell, Hannah, Sanchez, Marion O, Parsons, Marianne, Schultz, André, Torzillo, Paul J, West, Nicholas P, Versteegh, Lesley, Marchant, Julie M and Grimwood, Keith (2024). Erdosteine in children and adults with bronchiectasis (BETTER trial): study protocol for a multicentre, double-blind, randomised controlled trial. BMJ Open Respiratory Research, 11 (1) e002216, e002216. doi: 10.1136/bmjresp-2023-002216
2024
Journal Article
Efficacy of biologically-directed daylight therapy on sleep and circadian rhythm in Parkinson's disease: a randomised, double-blind, parallel-group, active-controlled, phase 2 clinical trial
Feigl, Beatrix, Lewis, Simon J.G., Burr, Lucy D., Schweitzer, Daniel, Gnyawali, Subodh, Vagenas, Dimitrios, Carter, Drew D. and Zele, Andrew J. (2024). Efficacy of biologically-directed daylight therapy on sleep and circadian rhythm in Parkinson's disease: a randomised, double-blind, parallel-group, active-controlled, phase 2 clinical trial. eClinicalMedicine, 69 102474, 102474. doi: 10.1016/j.eclinm.2024.102474
2024
Journal Article
Immunogenicity and safety of a bivalent (omicron BA.5 plus ancestral) SARS-CoV-2 recombinant spike protein vaccine as a heterologous booster dose: interim analysis of a phase 3, non-inferiority, randomised, clinical trial
Bennett, Chijioke, Woo, Wayne, Bloch, Mark, Cheung, King, Griffin, Paul, Mohan, Rahul, Deshmukh, Sachin, Arya, Mark, Cumming, Oscar, Neville, A Munro, McCallum Pardey, Toni G, Plested, Joyce S, Cloney-Clark, Shane, Zhu, Mingzhu, Kalkeri, Raj, Patel, Nita, Marcheschi, Alex, Swan, Jennifer, Smith, Gale, Cho, Iksung, Glenn, Gregory M, Walker, Robert, Mallory, Raburn M, Anderson, Anna, Ang, Mary, Barnes, Timothy, Bassin, Michelle, Bessey, Kate, Bowler, Simon ... Young, Rhys (2024). Immunogenicity and safety of a bivalent (omicron BA.5 plus ancestral) SARS-CoV-2 recombinant spike protein vaccine as a heterologous booster dose: interim analysis of a phase 3, non-inferiority, randomised, clinical trial. The Lancet Infectious Diseases, 24 (6), 581-593. doi: 10.1016/S1473-3099(24)00077-X
2023
Journal Article
The role of N-glycosylation in spike antigenicity for the SARS-CoV-2 gamma variant
Pegg, Cassandra L., Modhiran, Naphak, Parry, Rhys H., Liang, Benjamin, Amarilla, Alberto A., Khromykh, Alexander A., Burr, Lucy, Young, Paul R., Chappell, Keith, Schulz, Benjamin L. and Watterson, Daniel (2023). The role of N-glycosylation in spike antigenicity for the SARS-CoV-2 gamma variant. Glycobiology, 34 (2) cwad097, 1-13. doi: 10.1093/glycob/cwad097
2023
Journal Article
Elevated BMI reduces the humoral response to SARS‐CoV‐2 infection
Tong, Marcus Z. W., Sng, Julian D. J., Carney, Meagan, Cooper, Lucy, Brown, Samuel, Lineburg, Katie E., Chew, Keng Yih, Collins, Neve, Ignacio, Kirsten, Airey, Megan, Burr, Lucy, Joyce, Briony A., Jayasinghe, Dhilshan, McMillan, Christopher L. D., Muller, David A., Adhikari, Anurag, Gallo, Linda A., Dorey, Emily S., Barrett, Helen L., Gras, Stephanie, Smith, Corey, Good‐Jacobson, Kim and Short, Kirsty R. (2023). Elevated BMI reduces the humoral response to SARS‐CoV‐2 infection. Clinical and Translational Immunology, 12 (12) e1476, 1-13. doi: 10.1002/cti2.1476
2023
Journal Article
Genomic analyses of Burkholderia respiratory isolates indicates two evolutionarily distinct B. anthina clades
Pham, Amy, Volmer, James G., Chambers, Daniel C., Smith, Daniel J., Reid, David W., Burr, Lucy and Wells, Timothy J. (2023). Genomic analyses of Burkholderia respiratory isolates indicates two evolutionarily distinct B. anthina clades. Frontiers in Microbiology, 14 1274280, 1-14. doi: 10.3389/fmicb.2023.1274280
2023
Journal Article
The impact of long-term macrolide exposure on the gut microbiome and its implications for metabolic control
Choo, Jocelyn M., Martin, Alyce M., Taylor, Steven L., Sun, Emily, Mobegi, Fredrick M., Kanno, Tokuwa, Richard, Alyson, Burr, Lucy D., Lingman, Stevie, Martin, Megan, Keating, Damien J., Mason, A. James and Rogers, Geraint B. (2023). The impact of long-term macrolide exposure on the gut microbiome and its implications for metabolic control. Microbiology Spectrum, 11 (4). doi: 10.1128/spectrum.00831-23
2023
Journal Article
Subjective and objective sleep quality does not predict behavioural episodic foresight in younger or older adults
Demichelis, Olivia P., Grainger, Sarah A., McKay, Kate T., Burr, Lucy, Kim, Joanne and Henry, Julie D. (2023). Subjective and objective sleep quality does not predict behavioural episodic foresight in younger or older adults. Scientific Reports, 13 (1) 1056, 1-10. doi: 10.1038/s41598-023-28183-1
2023
Journal Article
Safety and efficacy of vanzacaftor–tezacaftor–deutivacaftor in adults with cystic fibrosis: randomised, double-blind, controlled, phase 2 trials
Uluer, Ahmet Z, MacGregor, Gordon, Azevedo, Pilar, Indihar, Veronica, Keating, Claire, Mall, Marcus A, McKone, Edward F, Ramsey, Bonnie W, Rowe, Steven M, Rubenstein, Ronald C, Taylor-Cousar, Jennifer L, Tullis, Elizabeth, Yonker, Lael M, Chu, Chenghao, Lam, Anna P, Nair, Nitin, Sosnay, Patrick R, Tian, Simon, Van Goor, Fredrick, Viswanathan, Lakshmi, Waltz, David, Wang, Linda T, Xi, Yingmei, Billings, Joanne, Horsley, Alexander, Nash, Edward F., Bakker, Marleen, van der Meer, Renske, Merkus, Petrus ... Wilson, John (2023). Safety and efficacy of vanzacaftor–tezacaftor–deutivacaftor in adults with cystic fibrosis: randomised, double-blind, controlled, phase 2 trials. The Lancet Respiratory Medicine, 11 (6), 550-562. doi: 10.1016/S2213-2600(22)00504-5
2023
Journal Article
‘Teach me how to look after myself’: what people with bronchiectasis want from education in a pulmonary rehabilitation setting
Lee, Annemarie L., Smith, Rebecca, Burr, Lucy, Chang, Anne B., Holmes‐Liew, Chien‐Li, King, Paul, Middleton, Peter, Morgan, Lucy, Smith, Daniel, Thomson, Rachel, Waterer, Grant, Wong, Conroy and McAleer, Rachael (2023). ‘Teach me how to look after myself’: what people with bronchiectasis want from education in a pulmonary rehabilitation setting. The Clinical Respiratory Journal, 17 (1), 59-69. doi: 10.1111/crj.13563
2023
Journal Article
GPR183 antagonism reduces macrophage infiltration in influenza and SARS-CoV-2 infection
Foo, Cheng Xiang, Bartlett, Stacey, Chew, Keng Yih, Ngo, Minh Dao, Bielefeldt-Ohmann, Helle, Jayakody Arachchige, Buddhika, Matthews, Benjamin, Reed, Sarah, Wang, Ran, Smith, Christian, Sweet, Matthew J., Burr, Lucy, Bisht, Kavita, Shatunova, Svetlana, Sinclair, Jane E., Parry, Rhys, Yang, Yuanhao, Lévesque, Jean-Pierre, Khromykh, Alexander, Rosenkilde, Mette Marie, Short, Kirsty R. and Ronacher, Katharina (2023). GPR183 antagonism reduces macrophage infiltration in influenza and SARS-CoV-2 infection. European Respiratory Journal, 61 (3) 2201306, 1-15. doi: 10.1183/13993003.01306-2022
2022
Journal Article
Pregnancy in women with cystic fibrosis and diabetes: an audit of outcomes at two tertiary obstetric hospitals in Australia in the pre-cystic fibrosis transmembrane conductance regulator modulator era
Davidson, Sarah J., France, Megan, Callaway, Leonie K., Lust, Karin, Chambers, Daniel, Hopkins, Peter, Bell, Scott C., Burr, Lucy, Keating, Rebecca and Barrett, Helen L. (2022). Pregnancy in women with cystic fibrosis and diabetes: an audit of outcomes at two tertiary obstetric hospitals in Australia in the pre-cystic fibrosis transmembrane conductance regulator modulator era. Obstetric Medicine, 16 (4), 217-221. doi: 10.1177/1753495x221146342
2022
Journal Article
Care for adults with COVID-19: living guidelines from the National COVID-19 Clinical Evidence Taskforce
White, Heath, McDonald, Steve J, Barber, Bridget, Davis, Joshua, Burr, Lucy, Nair, Priya, Mukherjee, Sutapa, Tendal, Britta, Elliott, Julian, McGloughlin, Steven and Turner, Tari (2022). Care for adults with COVID-19: living guidelines from the National COVID-19 Clinical Evidence Taskforce. Medical Journal of Australia, 217 (7), 368-378. doi: 10.5694/mja2.51718
2022
Journal Article
Carriage and transmission of macrolide resistance genes in patients with chronic respiratory conditions and their close contacts
Wang, Yiming, Taylor, Steven L., Choo, Jocelyn M., Papanicolas, Lito E., Keating, Rebecca, Hindmarsh, Kate, Thomson, Rachel M., Morgan, Lucy, Rogers, Geraint B. and Burr, Lucy D. (2022). Carriage and transmission of macrolide resistance genes in patients with chronic respiratory conditions and their close contacts. Chest, 162 (1), 56-65. doi: 10.1016/j.chest.2022.01.045
2022
Journal Article
Rothia mucilaginosa is an anti-inflammatory bacterium in the respiratory tract of patients with chronic lung disease
Rigauts, Charlotte, Aizawa, Juliana, Taylor, Steven L., Rogers, Geraint B., Govaerts, Matthias, Cos, Paul, Ostyn, Lisa, Sims, Sarah, Vandeplassche, Eva, Sze, Mozes, Dondelinger, Yves, Vereecke, Lars, Van Acker, Heleen, Simpson, Jodie L., Burr, Lucy, Willems, Anne, Tunney, Michael M., Cigana, Cristina, Bragonzi, Alessandra, Coenye, Tom and Crabbé, Aurélie (2022). Rothia mucilaginosa is an anti-inflammatory bacterium in the respiratory tract of patients with chronic lung disease. European Respiratory Journal, 59 (5) 2101293, 1-16. doi: 10.1183/13993003.01293-2021
2022
Journal Article
Assessment of long-term macrolide exposure on the oropharyngeal microbiome and macrolide resistance in healthy adults and consequences for onward transmission of resistance
Burr, Lucy D., Taylor, Steven L., Richard, Alyson, Schreiber, Veronika, Lingman, Stevie, Martin, Megan, Papanicolas, Lito E., Choo, Jocelyn M. and Rogers, Geraint B. (2022). Assessment of long-term macrolide exposure on the oropharyngeal microbiome and macrolide resistance in healthy adults and consequences for onward transmission of resistance. Antimicrobial Agents and Chemotherapy, 66 (4) ARTN e02246-21. doi: 10.1128/aac.02246-21
Funding
Current funding
Supervision
Availability
- Associate Professor Lucy Burr is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
An investigation into the factors influencing glucose control in cystic fibrosis
Principal Advisor
-
Doctor Philosophy
Achieving Remission in Asthma
Principal Advisor
Other advisors: Dr Sumaira Hasnain
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Doctor Philosophy
Decline of Unfolded Protein Response with Age Increases Susceptibility to Infection and Inflammation
Associate Advisor
Other advisors: Dr Sumaira Hasnain
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Doctor Philosophy
The contribution of neutrophils to the immunopathology of severe viral bronchiolitis, asthma and bronchiectasis
Associate Advisor
-
Doctor Philosophy
The Neuroinflammatory Hypothesis: Assessing the Relationship Between Sleep Dysfunction and Multiple Sclerosis
Associate Advisor
Other advisors: Professor Julie Henry
Completed supervision
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2023
Doctor Philosophy
Sleep and Psychological Function: The Relationship Between Sleep with Stress, Aggression, and Episodic Foresight
Associate Advisor
Other advisors: Dr Sarah Grainger, Professor Julie Henry
Media
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