Overview
Background
A/Prof Lucy Burr is an experienced respiratory physician, training supervisor and clinical trials researcher at Mater Health and Mater Research – University of Queensland (UQ). She has a PhD (2017) in bronchiectasis microbiology and is an Associate Professor at the School of Medicine, UQ. She is the Director of Respiratory, Sleep and Cystic Fibrosis medicine at the Mater Hospital, Brisbane.
As well as directing the respiratory clinical service at the Mater, Lucy has an active role in teaching both specialist trainees and medical students. She is a RACP college supervisor and trains one advanced trainee and four basic trainees per year. She directly supervises four medical students in her clinical team per year. Lucy is also currently supervising 5 PhD students, researching diverse fields such as glucose control in cystic fibrosis, asthma, fatigue, IL-22 and the effect of sleep on social cognition.
Lucy is recognised nationally for her clinical work on respiratory infections. She is the chair of the Acute and Critical Care panel for the National COVID-19 clinical evidence taskforce and a member of the guideline leadership group. Additionally, she is the recent chair (2020-2022) of the expert reference group on COVID-19 for the Royal Australasian College of Physicians. She is a recent (2019- 2021) convenor of the respiratory infectious disease special interest group of the Thoracic Society of Australia and New Zealand, the Queensland TSANZ branch president and past president (2017-2020), a recent board director of the TSANZ national body and current Chair of the Australian Bronchiectasis Consortium. Lucy is currently serving on the TSANZ annual scientific meeting and World Bronchiectasis conference steering committees. She is recognised internationally for her work on Cystic Fibrosis (top 1.8% expertscape February 2024) and Bronchiectasis (top 2.2% expertscape February 2024) and has published in high impact clinical journals including the New England Journal of Medicine and the Lancet Respiratory Medicine, across a range of respiratory and infectious disease subjects, with >1500 citations in the past 5 years.
In addition to her clinical work, Lucy is the custodian and manager of the David Serisier Research biobank at Mater Research, a clinical repository of human samples from patients living with respiratory diseases. Lucy is also an experienced principal investigator on many pharmaceutical studies ranging from phase 1b to phase 4 studies investigating therapeutics for CF, IPF, COPD, COVID, influenza pulmonary hypertension and bronchiectasis. She has designed and lead non-pharmaceutical interventional studies investigating the role of macrolide in modulating inflammation in healthy adults. She is the group leader of the respiratory clinical trials unit at Mater Research, and the program lead for the chronic and integrated care program at Mater Research.
Lucy has a proven track record in collaborative and translational research. She is currently a consultant on 2 peer reviewed external grants totalling $1,306,000, including one involving biobanked samples, and is a chief investigator on a 2021 Ideas grant and a 2021 MRFF grant totalling more than $3 million dollars.
Availability
- Associate Professor Lucy Burr is:
- Available for supervision
Fields of research
Qualifications
- Bachelor (Honours) of Medical Sciences, King's College London
- Bachelor of Medicine and Surgery and Medical Science, King's College London
- Doctor of Philosophy of Respiratory Diseases, The University of Queensland
- Diploma of Leadership and Management, unknown
- Fellow, Royal Australasian College of Physicians, Royal Australasian College of Physicians
- Fellow, Thoracic Society of Australia & New Zealand, Thoracic Society of Australia & New Zealand
Works
Search Professor Lucy Burr’s works on UQ eSpace
2022
Journal Article
Targeting the P2Y13 receptor suppresses IL-33 and HMGB1 release and ameliorates experimental asthma
Werder, Rhiannon B., Ullah, Md Ashik, Rahman, Muhammed Mahfuzur, Simpson, Jennifer, Lynch, Jason P., Collinson, Natasha, Rittchen, Sonja, Rashid, Ridwan B., Sikder, Md Al Amin, Handoko, Herlina Y., Curren, Bodie F., Sebina, Ismail, Hartel, Gunter, Bissell, Alec, Ngo, Sylvia, Yarlagadda, Tejasri, Hasnain, Sumaira Z., Lu, Wenying, Sohal, Sukhwinder S., Martin, Megan, Bowler, Simon, Burr, Lucy D., Martinez, Laurent O., Robaye, Bernard, Spann, Kirsten, Ferreira, Manuel A. R. and Phipps, Simon (2022). Targeting the P2Y13 receptor suppresses IL-33 and HMGB1 release and ameliorates experimental asthma. American Journal of Respiratory and Critical Care Medicine, 205 (3), 300-312. doi: 10.1164/rccm.202009-3686oc
2020
Journal Article
The cystic fibrosis gut as a potential source of multidrug resistant pathogens
Taylor, Steven L., Leong, Lex E. X., Sims, Sarah K., Keating, Rebecca L., Papanicolas, Lito E., Richard, Alyson, Mobegi, Fredrick M., Wesselingh, Steve, Burr, Lucy D. and Rogers, Geraint B. (2020). The cystic fibrosis gut as a potential source of multidrug resistant pathogens. Journal of Cystic Fibrosis, 20 (3), 413-420. doi: 10.1016/j.jcf.2020.11.009
2020
Journal Article
Improving antenatal asthma management: a complex journey
Chen, Clarissa, Meng-Wong Taing, Burr, Lucy, Barrett, Helen L. and Clifton, Vicki L. (2020). Improving antenatal asthma management: a complex journey. EMJ Respiratory, 97-107. doi: 10.33590/emjrespir/20-00143
2020
Conference Publication
CARRIAGE AND TRANSMISSION OF MACROLIDE RESISTANCE GENES IN PATIENTS WITH CHRONIC LUNG DISEASES
Wang, Y., Taylor, S., Basham, J., Keating, R., Hindmarsh, K., Choo, J., Wesselingh, S., Burr, L. and Rogers, G. (2020). CARRIAGE AND TRANSMISSION OF MACROLIDE RESISTANCE GENES IN PATIENTS WITH CHRONIC LUNG DISEASES. HOBOKEN: WILEY.
2020
Journal Article
Airway mucus hyperconcentration in non–cystic fibrosis bronchiectasis
Ramsey, Kathryn A., Chen, Alice C. H., Radicioni, Giorgia, Lourie, Rohan, Martin, Megan, Broomfield, Amy, Sheng, Yong H., Hasnain, Sumaira Z., Radford-Smith, Graham, Simms, Lisa A., Burr, Lucy, Thornton, David J., Bowler, Simon D., Livengood, Stephanie, Ceppe, Agathe, Knowles, Michael R., Noone, Peadar G., Donaldson, Scott H., Hill, David B., Ehre, Camille, Button, Brian, Alexis, Neil E., Kesimer, Mehmet, Boucher, Richard C. and McGuckin, Michael A. (2020). Airway mucus hyperconcentration in non–cystic fibrosis bronchiectasis. American Journal of Respiratory and Critical Care Medicine, 201 (6), 661-670. doi: 10.1164/rccm.201906-1219OC
2020
Conference Publication
Harnessing the therapeutic potential of interleukin-22 in neonatal respiratory viral infection
Hasnain, S., Wang, R., Taylor, S., Wong, K. Y., Moniruzzaman, M., Upham, J., Spann, K., Mcguckin, M. A., Burr, L. and Phipps, S. (2020). Harnessing the therapeutic potential of interleukin-22 in neonatal respiratory viral infection. TSANZSRS 2020 The Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ) Annual Scientific Meeting for Leaders in Lung Health & Respiratory Science, Melbourne, VIC, Australia, 27–31 March 2020. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/resp.13777
2019
Journal Article
Management of Australian adults with bronchiectasis in tertiary care: evidence-based or access-driven?
Visser, Simone K., Bye, Peter T. P., Fox, Greg J., Burr, Lucy D., Chang, Anne B., Holmes-Liew, Chien-Li, King, Paul, Middleton, Peter G., Maguire, Graeme P., Smith, Daniel, Thomson, Rachel M., Stroil-Salama, Enna, Britton, Warwick J. and Morgan, Lucy C. (2019). Management of Australian adults with bronchiectasis in tertiary care: evidence-based or access-driven?. Lung, 197 (6), 803-810. doi: 10.1007/s00408-019-00280-x
2019
Journal Article
Long-term macrolide antibiotics for the treatment of bronchiectasis in adults: an individual participant data meta-analysis
Chalmers, James D, Boersma, Wim, Lonergan, Mike, Jayaram, Lata, Crichton, Megan L, Karalus, Noel, Taylor, Steven L, Martin, Megan L, Burr, Lucy D, Wong, Conroy and Altenburg, Josje (2019). Long-term macrolide antibiotics for the treatment of bronchiectasis in adults: an individual participant data meta-analysis. Lancet Respiratory Medicine, 7 (10), 845-854. doi: 10.1016/s2213-2600(19)30191-2
2019
Journal Article
The impact of CFTR modulator therapies on CF airway microbiology
Rogers, Geraint B., Taylor, Steven L., Hoffman, Lucas R. and Burr, Lucy D. (2019). The impact of CFTR modulator therapies on CF airway microbiology. Journal of Cystic Fibrosis, 19 (3), 359-364. doi: 10.1016/j.jcf.2019.07.008
2019
Journal Article
Australian adults with bronchiectasis: the first report from the Australian bronchiectasis registry
Visser, Simone K., Bye, Peter T.P., Fox, Greg J., Burr, Lucy D., Chang, Anne B., Holmes-Liew, Chien-Li, King, Paul, Middleton, Peter G., Maguire, Graeme P., Smith, Daniel, Thomson, Rachel M., Stroil-Salama, Enna, Britton, Warwick J. and Morgan, Lucy C. (2019). Australian adults with bronchiectasis: the first report from the Australian bronchiectasis registry. Respiratory Medicine, 155, 97-103. doi: 10.1016/j.rmed.2019.07.016
2019
Journal Article
Lumacaftor/ivacaftor reduces exacerbations in adults homozygous for Phe508del mutation with severe lung disease
Tong, Koliarne, Barker, Daniel, France, Megan, Burr, Lucy, Greville, Hugh, Visser, Simone, Middleton, Peter, Wainwright, Claire, Dorahy, Douglas and Wark, Peter (2019). Lumacaftor/ivacaftor reduces exacerbations in adults homozygous for Phe508del mutation with severe lung disease. Journal of Cystic Fibrosis, 19 (3), 415-420. doi: 10.1016/j.jcf.2019.12.006
2019
Conference Publication
Relating Airway Microbiota Composition to Nontuberculous Mycobacterial Infections in Adult Bronchiectasis Patients
Thomson, R., Scoleri, G., Taylor, S., Leong, L., Burr, L. and Rogers, G. (2019). Relating Airway Microbiota Composition to Nontuberculous Mycobacterial Infections in Adult Bronchiectasis Patients. International Conference of the American-Thoracic-Society, Dallas Tx, May 17-22, 2019. NEW YORK: AMER THORACIC SOC. doi: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1035
2018
Journal Article
Opportunistic bacteria confer the ability to ferment prebiotic starch in the adult cystic fibrosis gut
Wang, Yanan, Leong, Lex E.X., Keating, Rebecca L., Kanno, Tokuwa, Abell, Guy C.J., Mobegi, Fredrick M., Choo, Jocelyn M., Wesselingh, Steve L., Mason, A. James, Burr, Lucy D. and Rogers, Geraint B. (2018). Opportunistic bacteria confer the ability to ferment prebiotic starch in the adult cystic fibrosis gut. Gut Microbes, 10 (3), 1-15. doi: 10.1080/19490976.2018.1534512
2018
Journal Article
VX-445-tezacaftor-ivacaftor in patients with cystic fibrosis and one or two Phe508del alleles
Keating, Dominic, Marigowda, Gautham, Burr, Lucy, Daines, Cori, Mall, Marcus A., McKone, Edward F., Ramsey, Bonnie W., Rowe, Steven M., Sass, Laura A., Tullis, Elizabeth, McKee, Charlotte M., Moskowitz, Samuel M., Robertson, Sarah, Savage, Jessica, Simard, Christopher, Van Goor, Fredrick, Waltz, David, Xuan, Fengjuan, Young, Tim and Taylor-Cousar, Jennifer L. (2018). VX-445-tezacaftor-ivacaftor in patients with cystic fibrosis and one or two Phe508del alleles. New England Journal of Medicine, 379 (17), 1612-1620. doi: 10.1056/NEJMoa1807120
2018
Journal Article
PPARγ is reduced in the airways of non-CF bronchiectasis subjects and is inversely correlated with the presence of Pseudomonas aeruginosa
Burr, Lucy D., Rogers, Geraint B., Chen, Alice C.-H., Taylor, Steven L., Bowler, Simon D., Keating, Rebecca L., Martin, Megan L., Hasnain, Sumaira Z. and McGuckin, Michael A. (2018). PPARγ is reduced in the airways of non-CF bronchiectasis subjects and is inversely correlated with the presence of Pseudomonas aeruginosa. PLoS ONE, 13 (8) e0202296, e0202296. doi: 10.1371/journal.pone.0202296
2018
Journal Article
Understanding the impact of antibiotic therapies on the respiratory tract resistome: a novel pooled-template metagenomic sequencing strategy
Taylor, Steven L., Leong, Lex E. X., Mobegi, Fredrick M., Choo, Jocelyn M., Burr, Lucy D., Wesselingh, Steve and Rogers, Geraint B. (2018). Understanding the impact of antibiotic therapies on the respiratory tract resistome: a novel pooled-template metagenomic sequencing strategy. Multidisciplinary Respiratory Medicine, 13 (S1) 30, 30. doi: 10.1186/s40248-018-0140-9
2018
Journal Article
Impact of long-term erythromycin therapy on the oropharyngeal microbiome and resistance gene reservoir in non-cystic fibrosis bronchiectasis
Choo, Jocelyn M., Abell, Guy C. J., Thomson, Rachel, Morgan, Lucy, Waterer, Grant, Gordon, David L., Taylor, Steven L., Leong, Lex E. X., Wesselingh, Steve L., Burr, Lucy D. and Rogers, Geraint B. (2018). Impact of long-term erythromycin therapy on the oropharyngeal microbiome and resistance gene reservoir in non-cystic fibrosis bronchiectasis. mSphere, 3 (2) e00103-18, e00103-18. doi: 10.1128/mSphere.00103-18
2017
Other Outputs
An investigation into the effect of erythromycin on Pseudomonas aeruginosa quorum sensing in non-cystic fibrosis bronchiectasis
Burr, Lucy Davina (2017). An investigation into the effect of erythromycin on Pseudomonas aeruginosa quorum sensing in non-cystic fibrosis bronchiectasis. PhD Thesis, School of Medicine, The University of Queensland. doi: 10.14264/uql.2017.836
2017
Conference Publication
The Australasian Bronchiectasis Registry - Early Steps in Mapping the Impact of Bronchiectasis in Australia and New Zealand
Visser, Simone, Allan, Heather, Burr, Lucy, Chang, Anne, Holmes-Liew, Chien-Li, Hunter, Cameron, Jackson, Dan, King, Paul, Maguire, Graeme, Middleton, Peter, Smith, Daniel, Thomson, Rachel, Waterer, Grant, Wong, Conroy and Morgan, Lucy (2017). The Australasian Bronchiectasis Registry - Early Steps in Mapping the Impact of Bronchiectasis in Australia and New Zealand. The Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ) Annual Scientific Meeting, Canberra, Australia, 24–28 March 2017. Richmond, VIC Australia: Wiley.
2016
Journal Article
Macrolide treatment inhibits Pseudomonas aeruginosa quorum sensing in non-cystic fibrosis bronchiectasis. An analysis from the bronchiectasis and low-dose erythromycin study trial
Burr, Lucy D., Rogers, Geraint B., Chen, Alice C.-H., Hamilton, Brett R., Pool, Gertruida F., Taylor, Steven L., Venter, Deon, Bowler, Simon D., Biga, Sally and McGuckin, Michael A. (2016). Macrolide treatment inhibits Pseudomonas aeruginosa quorum sensing in non-cystic fibrosis bronchiectasis. An analysis from the bronchiectasis and low-dose erythromycin study trial. Annals of the American Thoracic Society, 13 (10), 1697-1703. doi: 10.1513/AnnalsATS.201601-044OC
Funding
Current funding
Supervision
Availability
- Associate Professor Lucy Burr is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
An investigation into the factors influencing glucose control in cystic fibrosis
Principal Advisor
-
Doctor Philosophy
Achieving Remission in Asthma
Principal Advisor
Other advisors: Dr Sumaira Hasnain
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Doctor Philosophy
The contribution of neutrophils to the immunopathology of severe viral bronchiolitis, asthma and bronchiectasis
Associate Advisor
-
Doctor Philosophy
The Neuroinflammatory Hypothesis: Assessing the Relationship Between Sleep Dysfunction and Multiple Sclerosis
Associate Advisor
Other advisors: Professor Julie Henry
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Doctor Philosophy
Decline of Unfolded Protein Response with Age Increases Susceptibility to Infection and Inflammation
Associate Advisor
Other advisors: Dr Sumaira Hasnain
Completed supervision
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2023
Doctor Philosophy
Sleep and Psychological Function: The Relationship Between Sleep with Stress, Aggression, and Episodic Foresight
Associate Advisor
Other advisors: Dr Sarah Grainger, Professor Julie Henry
Media
Enquiries
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