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Associate Professor Lucy Burr
Associate Professor

Lucy Burr

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Overview

Background

A/Prof Lucy Burr is an experienced respiratory physician, training supervisor and clinical trials researcher at Mater Health and Mater Research – University of Queensland (UQ). She has a PhD (2017) in bronchiectasis microbiology and is an Associate Professor at the School of Medicine, UQ. She is the Director of Respiratory, Sleep and Cystic Fibrosis medicine at the Mater Hospital, Brisbane.

As well as directing the respiratory clinical service at the Mater, Lucy has an active role in teaching both specialist trainees and medical students. She is a RACP college supervisor and trains one advanced trainee and four basic trainees per year. She directly supervises four medical students in her clinical team per year. Lucy is also currently supervising 5 PhD students, researching diverse fields such as glucose control in cystic fibrosis, asthma, fatigue, IL-22 and the effect of sleep on social cognition.

Lucy is recognised nationally for her clinical work on respiratory infections. She is the chair of the Acute and Critical Care panel for the National COVID-19 clinical evidence taskforce and a member of the guideline leadership group. Additionally, she is the recent chair (2020-2022) of the expert reference group on COVID-19 for the Royal Australasian College of Physicians. She is a recent (2019- 2021) convenor of the respiratory infectious disease special interest group of the Thoracic Society of Australia and New Zealand, the Queensland TSANZ branch president and past president (2017-2020), a recent board director of the TSANZ national body and current Chair of the Australian Bronchiectasis Consortium. Lucy is currently serving on the TSANZ annual scientific meeting and World Bronchiectasis conference steering committees. She is recognised internationally for her work on Cystic Fibrosis (top 1.8% expertscape February 2024) and Bronchiectasis (top 2.2% expertscape February 2024) and has published in high impact clinical journals including the New England Journal of Medicine and the Lancet Respiratory Medicine, across a range of respiratory and infectious disease subjects, with >1500 citations in the past 5 years.

In addition to her clinical work, Lucy is the custodian and manager of the David Serisier Research biobank at Mater Research, a clinical repository of human samples from patients living with respiratory diseases. Lucy is also an experienced principal investigator on many pharmaceutical studies ranging from phase 1b to phase 4 studies investigating therapeutics for CF, IPF, COPD, COVID, influenza pulmonary hypertension and bronchiectasis. She has designed and lead non-pharmaceutical interventional studies investigating the role of macrolide in modulating inflammation in healthy adults. She is the group leader of the respiratory clinical trials unit at Mater Research, and the program lead for the chronic and integrated care program at Mater Research.

Lucy has a proven track record in collaborative and translational research. She is currently a consultant on 2 peer reviewed external grants totalling $1,306,000, including one involving biobanked samples, and is a chief investigator on a 2021 Ideas grant and a 2021 MRFF grant totalling more than $3 million dollars.

Availability

Associate Professor Lucy Burr is:
Available for supervision

Qualifications

  • Bachelor (Honours) of Medical Sciences, King's College London
  • Bachelor of Medicine and Surgery and Medical Science, King's College London
  • Doctor of Philosophy of Respiratory Diseases, The University of Queensland
  • Diploma of Leadership and Management, unknown
  • Fellow, Royal Australasian College of Physicians, Royal Australasian College of Physicians
  • Fellow, Thoracic Society of Australia & New Zealand, Thoracic Society of Australia & New Zealand

Works

Search Professor Lucy Burr’s works on UQ eSpace

56 works between 2012 and 2024

21 - 40 of 56 works

2022

Journal Article

Targeting the P2Y13 receptor suppresses IL-33 and HMGB1 release and ameliorates experimental asthma

Werder, Rhiannon B., Ullah, Md Ashik, Rahman, Muhammed Mahfuzur, Simpson, Jennifer, Lynch, Jason P., Collinson, Natasha, Rittchen, Sonja, Rashid, Ridwan B., Sikder, Md Al Amin, Handoko, Herlina Y., Curren, Bodie F., Sebina, Ismail, Hartel, Gunter, Bissell, Alec, Ngo, Sylvia, Yarlagadda, Tejasri, Hasnain, Sumaira Z., Lu, Wenying, Sohal, Sukhwinder S., Martin, Megan, Bowler, Simon, Burr, Lucy D., Martinez, Laurent O., Robaye, Bernard, Spann, Kirsten, Ferreira, Manuel A. R. and Phipps, Simon (2022). Targeting the P2Y13 receptor suppresses IL-33 and HMGB1 release and ameliorates experimental asthma. American Journal of Respiratory and Critical Care Medicine, 205 (3), 300-312. doi: 10.1164/rccm.202009-3686oc

Targeting the P2Y13 receptor suppresses IL-33 and HMGB1 release and ameliorates experimental asthma

2020

Journal Article

The cystic fibrosis gut as a potential source of multidrug resistant pathogens

Taylor, Steven L., Leong, Lex E. X., Sims, Sarah K., Keating, Rebecca L., Papanicolas, Lito E., Richard, Alyson, Mobegi, Fredrick M., Wesselingh, Steve, Burr, Lucy D. and Rogers, Geraint B. (2020). The cystic fibrosis gut as a potential source of multidrug resistant pathogens. Journal of Cystic Fibrosis, 20 (3), 413-420. doi: 10.1016/j.jcf.2020.11.009

The cystic fibrosis gut as a potential source of multidrug resistant pathogens

2020

Journal Article

Improving antenatal asthma management: a complex journey

Chen, Clarissa, Meng-Wong Taing, Burr, Lucy, Barrett, Helen L. and Clifton, Vicki L. (2020). Improving antenatal asthma management: a complex journey. EMJ Respiratory, 97-107. doi: 10.33590/emjrespir/20-00143

Improving antenatal asthma management: a complex journey

2020

Conference Publication

CARRIAGE AND TRANSMISSION OF MACROLIDE RESISTANCE GENES IN PATIENTS WITH CHRONIC LUNG DISEASES

Wang, Y., Taylor, S., Basham, J., Keating, R., Hindmarsh, K., Choo, J., Wesselingh, S., Burr, L. and Rogers, G. (2020). CARRIAGE AND TRANSMISSION OF MACROLIDE RESISTANCE GENES IN PATIENTS WITH CHRONIC LUNG DISEASES. HOBOKEN: WILEY.

CARRIAGE AND TRANSMISSION OF MACROLIDE RESISTANCE GENES IN PATIENTS WITH CHRONIC LUNG DISEASES

2020

Journal Article

Airway mucus hyperconcentration in non–cystic fibrosis bronchiectasis

Ramsey, Kathryn A., Chen, Alice C. H., Radicioni, Giorgia, Lourie, Rohan, Martin, Megan, Broomfield, Amy, Sheng, Yong H., Hasnain, Sumaira Z., Radford-Smith, Graham, Simms, Lisa A., Burr, Lucy, Thornton, David J., Bowler, Simon D., Livengood, Stephanie, Ceppe, Agathe, Knowles, Michael R., Noone, Peadar G., Donaldson, Scott H., Hill, David B., Ehre, Camille, Button, Brian, Alexis, Neil E., Kesimer, Mehmet, Boucher, Richard C. and McGuckin, Michael A. (2020). Airway mucus hyperconcentration in non–cystic fibrosis bronchiectasis. American Journal of Respiratory and Critical Care Medicine, 201 (6), 661-670. doi: 10.1164/rccm.201906-1219OC

Airway mucus hyperconcentration in non–cystic fibrosis bronchiectasis

2020

Conference Publication

Harnessing the therapeutic potential of interleukin-22 in neonatal respiratory viral infection

Hasnain, S., Wang, R., Taylor, S., Wong, K. Y., Moniruzzaman, M., Upham, J., Spann, K., Mcguckin, M. A., Burr, L. and Phipps, S. (2020). Harnessing the therapeutic potential of interleukin-22 in neonatal respiratory viral infection. TSANZSRS 2020 The Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ) Annual Scientific Meeting for Leaders in Lung Health & Respiratory Science, Melbourne, VIC, Australia, 27–31 March 2020. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/resp.13777

Harnessing the therapeutic potential of interleukin-22 in neonatal respiratory viral infection

2019

Journal Article

Management of Australian adults with bronchiectasis in tertiary care: evidence-based or access-driven?

Visser, Simone K., Bye, Peter T. P., Fox, Greg J., Burr, Lucy D., Chang, Anne B., Holmes-Liew, Chien-Li, King, Paul, Middleton, Peter G., Maguire, Graeme P., Smith, Daniel, Thomson, Rachel M., Stroil-Salama, Enna, Britton, Warwick J. and Morgan, Lucy C. (2019). Management of Australian adults with bronchiectasis in tertiary care: evidence-based or access-driven?. Lung, 197 (6), 803-810. doi: 10.1007/s00408-019-00280-x

Management of Australian adults with bronchiectasis in tertiary care: evidence-based or access-driven?

2019

Journal Article

Long-term macrolide antibiotics for the treatment of bronchiectasis in adults: an individual participant data meta-analysis

Chalmers, James D, Boersma, Wim, Lonergan, Mike, Jayaram, Lata, Crichton, Megan L, Karalus, Noel, Taylor, Steven L, Martin, Megan L, Burr, Lucy D, Wong, Conroy and Altenburg, Josje (2019). Long-term macrolide antibiotics for the treatment of bronchiectasis in adults: an individual participant data meta-analysis. Lancet Respiratory Medicine, 7 (10), 845-854. doi: 10.1016/s2213-2600(19)30191-2

Long-term macrolide antibiotics for the treatment of bronchiectasis in adults: an individual participant data meta-analysis

2019

Journal Article

The impact of CFTR modulator therapies on CF airway microbiology

Rogers, Geraint B., Taylor, Steven L., Hoffman, Lucas R. and Burr, Lucy D. (2019). The impact of CFTR modulator therapies on CF airway microbiology. Journal of Cystic Fibrosis, 19 (3), 359-364. doi: 10.1016/j.jcf.2019.07.008

The impact of CFTR modulator therapies on CF airway microbiology

2019

Journal Article

Australian adults with bronchiectasis: the first report from the Australian bronchiectasis registry

Visser, Simone K., Bye, Peter T.P., Fox, Greg J., Burr, Lucy D., Chang, Anne B., Holmes-Liew, Chien-Li, King, Paul, Middleton, Peter G., Maguire, Graeme P., Smith, Daniel, Thomson, Rachel M., Stroil-Salama, Enna, Britton, Warwick J. and Morgan, Lucy C. (2019). Australian adults with bronchiectasis: the first report from the Australian bronchiectasis registry. Respiratory Medicine, 155, 97-103. doi: 10.1016/j.rmed.2019.07.016

Australian adults with bronchiectasis: the first report from the Australian bronchiectasis registry

2019

Journal Article

Lumacaftor/ivacaftor reduces exacerbations in adults homozygous for Phe508del mutation with severe lung disease

Tong, Koliarne, Barker, Daniel, France, Megan, Burr, Lucy, Greville, Hugh, Visser, Simone, Middleton, Peter, Wainwright, Claire, Dorahy, Douglas and Wark, Peter (2019). Lumacaftor/ivacaftor reduces exacerbations in adults homozygous for Phe508del mutation with severe lung disease. Journal of Cystic Fibrosis, 19 (3), 415-420. doi: 10.1016/j.jcf.2019.12.006

Lumacaftor/ivacaftor reduces exacerbations in adults homozygous for Phe508del mutation with severe lung disease

2019

Conference Publication

Relating Airway Microbiota Composition to Nontuberculous Mycobacterial Infections in Adult Bronchiectasis Patients

Thomson, R., Scoleri, G., Taylor, S., Leong, L., Burr, L. and Rogers, G. (2019). Relating Airway Microbiota Composition to Nontuberculous Mycobacterial Infections in Adult Bronchiectasis Patients. International Conference of the American-Thoracic-Society, Dallas Tx, May 17-22, 2019. NEW YORK: AMER THORACIC SOC. doi: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1035

Relating Airway Microbiota Composition to Nontuberculous Mycobacterial Infections in Adult Bronchiectasis Patients

2018

Journal Article

Opportunistic bacteria confer the ability to ferment prebiotic starch in the adult cystic fibrosis gut

Wang, Yanan, Leong, Lex E.X., Keating, Rebecca L., Kanno, Tokuwa, Abell, Guy C.J., Mobegi, Fredrick M., Choo, Jocelyn M., Wesselingh, Steve L., Mason, A. James, Burr, Lucy D. and Rogers, Geraint B. (2018). Opportunistic bacteria confer the ability to ferment prebiotic starch in the adult cystic fibrosis gut. Gut Microbes, 10 (3), 1-15. doi: 10.1080/19490976.2018.1534512

Opportunistic bacteria confer the ability to ferment prebiotic starch in the adult cystic fibrosis gut

2018

Journal Article

VX-445-tezacaftor-ivacaftor in patients with cystic fibrosis and one or two Phe508del alleles

Keating, Dominic, Marigowda, Gautham, Burr, Lucy, Daines, Cori, Mall, Marcus A., McKone, Edward F., Ramsey, Bonnie W., Rowe, Steven M., Sass, Laura A., Tullis, Elizabeth, McKee, Charlotte M., Moskowitz, Samuel M., Robertson, Sarah, Savage, Jessica, Simard, Christopher, Van Goor, Fredrick, Waltz, David, Xuan, Fengjuan, Young, Tim and Taylor-Cousar, Jennifer L. (2018). VX-445-tezacaftor-ivacaftor in patients with cystic fibrosis and one or two Phe508del alleles. New England Journal of Medicine, 379 (17), 1612-1620. doi: 10.1056/NEJMoa1807120

VX-445-tezacaftor-ivacaftor in patients with cystic fibrosis and one or two Phe508del alleles

2018

Journal Article

PPARγ is reduced in the airways of non-CF bronchiectasis subjects and is inversely correlated with the presence of Pseudomonas aeruginosa

Burr, Lucy D., Rogers, Geraint B., Chen, Alice C.-H., Taylor, Steven L., Bowler, Simon D., Keating, Rebecca L., Martin, Megan L., Hasnain, Sumaira Z. and McGuckin, Michael A. (2018). PPARγ is reduced in the airways of non-CF bronchiectasis subjects and is inversely correlated with the presence of Pseudomonas aeruginosa. PLoS ONE, 13 (8) e0202296, e0202296. doi: 10.1371/journal.pone.0202296

PPARγ is reduced in the airways of non-CF bronchiectasis subjects and is inversely correlated with the presence of Pseudomonas aeruginosa

2018

Journal Article

Understanding the impact of antibiotic therapies on the respiratory tract resistome: a novel pooled-template metagenomic sequencing strategy

Taylor, Steven L., Leong, Lex E. X., Mobegi, Fredrick M., Choo, Jocelyn M., Burr, Lucy D., Wesselingh, Steve and Rogers, Geraint B. (2018). Understanding the impact of antibiotic therapies on the respiratory tract resistome: a novel pooled-template metagenomic sequencing strategy. Multidisciplinary Respiratory Medicine, 13 (S1) 30, 30. doi: 10.1186/s40248-018-0140-9

Understanding the impact of antibiotic therapies on the respiratory tract resistome: a novel pooled-template metagenomic sequencing strategy

2018

Journal Article

Impact of long-term erythromycin therapy on the oropharyngeal microbiome and resistance gene reservoir in non-cystic fibrosis bronchiectasis

Choo, Jocelyn M., Abell, Guy C. J., Thomson, Rachel, Morgan, Lucy, Waterer, Grant, Gordon, David L., Taylor, Steven L., Leong, Lex E. X., Wesselingh, Steve L., Burr, Lucy D. and Rogers, Geraint B. (2018). Impact of long-term erythromycin therapy on the oropharyngeal microbiome and resistance gene reservoir in non-cystic fibrosis bronchiectasis. mSphere, 3 (2) e00103-18, e00103-18. doi: 10.1128/mSphere.00103-18

Impact of long-term erythromycin therapy on the oropharyngeal microbiome and resistance gene reservoir in non-cystic fibrosis bronchiectasis

2017

Other Outputs

An investigation into the effect of erythromycin on Pseudomonas aeruginosa quorum sensing in non-cystic fibrosis bronchiectasis

Burr, Lucy Davina (2017). An investigation into the effect of erythromycin on Pseudomonas aeruginosa quorum sensing in non-cystic fibrosis bronchiectasis. PhD Thesis, School of Medicine, The University of Queensland. doi: 10.14264/uql.2017.836

An investigation into the effect of erythromycin on Pseudomonas aeruginosa quorum sensing in non-cystic fibrosis bronchiectasis

2017

Conference Publication

The Australasian Bronchiectasis Registry - Early Steps in Mapping the Impact of Bronchiectasis in Australia and New Zealand

Visser, Simone, Allan, Heather, Burr, Lucy, Chang, Anne, Holmes-Liew, Chien-Li, Hunter, Cameron, Jackson, Dan, King, Paul, Maguire, Graeme, Middleton, Peter, Smith, Daniel, Thomson, Rachel, Waterer, Grant, Wong, Conroy and Morgan, Lucy (2017). The Australasian Bronchiectasis Registry - Early Steps in Mapping the Impact of Bronchiectasis in Australia and New Zealand. The Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ) Annual Scientific Meeting, Canberra, Australia, 24–28 March 2017. Richmond, VIC Australia: Wiley.

The Australasian Bronchiectasis Registry - Early Steps in Mapping the Impact of Bronchiectasis in Australia and New Zealand

2016

Journal Article

Macrolide treatment inhibits Pseudomonas aeruginosa quorum sensing in non-cystic fibrosis bronchiectasis. An analysis from the bronchiectasis and low-dose erythromycin study trial

Burr, Lucy D., Rogers, Geraint B., Chen, Alice C.-H., Hamilton, Brett R., Pool, Gertruida F., Taylor, Steven L., Venter, Deon, Bowler, Simon D., Biga, Sally and McGuckin, Michael A. (2016). Macrolide treatment inhibits Pseudomonas aeruginosa quorum sensing in non-cystic fibrosis bronchiectasis. An analysis from the bronchiectasis and low-dose erythromycin study trial. Annals of the American Thoracic Society, 13 (10), 1697-1703. doi: 10.1513/AnnalsATS.201601-044OC

Macrolide treatment inhibits Pseudomonas aeruginosa quorum sensing in non-cystic fibrosis bronchiectasis. An analysis from the bronchiectasis and low-dose erythromycin study trial

Funding

Current funding

  • 2022 - 2025
    Predicting and preparing for the unfolding evolution of SARS-CoV-2
    NHMRC IDEAS Grants
    Open grant

Supervision

Availability

Associate Professor Lucy Burr is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    An investigation into the factors influencing glucose control in cystic fibrosis

    Principal Advisor

  • Doctor Philosophy

    Achieving Remission in Asthma

    Principal Advisor

    Other advisors: Dr Sumaira Hasnain

  • Doctor Philosophy

    The contribution of neutrophils to the immunopathology of severe viral bronchiolitis, asthma and bronchiectasis

    Associate Advisor

  • Doctor Philosophy

    The Neuroinflammatory Hypothesis: Assessing the Relationship Between Sleep Dysfunction and Multiple Sclerosis

    Associate Advisor

    Other advisors: Professor Julie Henry

  • Doctor Philosophy

    Decline of Unfolded Protein Response with Age Increases Susceptibility to Infection and Inflammation

    Associate Advisor

    Other advisors: Dr Sumaira Hasnain

Completed supervision

Media

Enquiries

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communications@uq.edu.au