Overview
Availability
- Dr David Eagles is:
- Available for supervision
Qualifications
- Doctor of Philosophy of Chemistry and Biochemistry, The University of Queensland
Works
Search Professor David Eagles’s works on UQ eSpace
2025
Journal Article
Genome of venomous caterpillar Doratifera vulnerans reveals recruitment of immune peptides and their adaptation as pain-inducing toxins
Goudarzi, Mohaddeseh H., Robinson, Samuel D., Cardoso, Fernanda C., Suryamohan, Kushal, Lawrence, Nicole, Eagles, David A., Hoang, Huy N., Vetter, Irina, Fairlie, David P., Seshagiri, Somasekar, King, Glenn F. and Walker, Andrew A. (2025). Genome of venomous caterpillar Doratifera vulnerans reveals recruitment of immune peptides and their adaptation as pain-inducing toxins. Proceedings of the National Academy of Sciences, 122 (49) e2513640122, 1-11. doi: 10.1073/pnas.2513640122
2025
Journal Article
Venom peptides across Asian and American tarantulas utilize dual pharmacology to target activation and fast inactivation of voltage-gated sodium channels
Nashikwala, Amatulla S., Kotapati, Charan, Eagles, David A., Lewis, Richard J. and Cardoso, Fernanda C. (2025). Venom peptides across Asian and American tarantulas utilize dual pharmacology to target activation and fast inactivation of voltage-gated sodium channels. Toxins, 17 (11) 561, 561. doi: 10.3390/toxins17110561
2024
Journal Article
Secondary structure propensities of the Ebola delta peptide E40 in solution and model membrane environments
Li, Jiayu, Eagles, David A., Tucker, Isaac J., Pereira Schmidt, Anneka C. and Deplazes, Evelyne (2024). Secondary structure propensities of the Ebola delta peptide E40 in solution and model membrane environments. Biophysical Chemistry, 314 107318, 1-9. doi: 10.1016/j.bpc.2024.107318
2024
Conference Publication
Mending achy-breaky hearts: cyclic peptide TL01 is an enhancer of cardiac intracellular protein-protein interactions and promotes heart contractility
Rojas-Azofeifa, Daniela, Passioura, Toby, McMillen, Timothy, Cheesman, Elisabeth, Saez, Natalie, Chow, Jonathan, Eagles, David, Norman, Alexander, Perry, Matthew, Molenar, Peter, Regnier, Michael, King, Glenn and Palpant, Nathan (2024). Mending achy-breaky hearts: cyclic peptide TL01 is an enhancer of cardiac intracellular protein-protein interactions and promotes heart contractility. 37th European Peptide Symposium 14th International Peptide Symposium, Florence, Italy, 25-29 August 2024. Oxford, United Kingdom: John Wiley & Sons.
2024
Conference Publication
In vitro evolution of cyclic peptide inhibitors of acid-sensing ion channel 1a for neuroprotective applications during stroke
Biggs, Kimberley, Passioura, Toby, Eagles, David and King, Glenn (2024). In vitro evolution of cyclic peptide inhibitors of acid-sensing ion channel 1a for neuroprotective applications during stroke. 37th European Peptide Symposium 14th International Peptide Symposium, Florence, Italy, 25-29 August 2024. Oxford, United Kingdom: John Wiley & Sons.
2024
Conference Publication
Development of an equipotent NaV1.1 and NaV1.7 inhibitor for the treatment of chronic visceral pain
Eagles, David, King, Glenn, Cardoso, Fernanda, Muttenthaler, Markus and Brierley, Stuart (2024). Development of an equipotent NaV1.1 and NaV1.7 inhibitor for the treatment of chronic visceral pain. 37th European Peptide Symposium 14th International Peptide Symposium, Florence, Italy, 25 - 29 August 2024. Hoboken, NJ, United States: Wiley.
2023
Conference Publication
Structure, function, and evolution of nettle caterpillar venom toxins
Goudarzi, Mohaddeseh H., Robinson, Samuel, Cardoso, Fernanda C., Lawrence, Nicole, Eagles, David, Chin, Y., King, Glenn F. and Walker, Andrew A. (2023). Structure, function, and evolution of nettle caterpillar venom toxins. V2D 2023: 8th Venoms to Drugs Conference, Moreton Island, QLD Australia, 9-13 October 2023.
2023
Journal Article
Horizontal gene transfer underlies the painful stings of asp caterpillars (Lepidoptera: Megalopygidae)
Walker, Andrew A., Robinson, Samuel D., Merritt, David J., Cardoso, Fernanda C., Goudarzi, Mohaddeseh Hedayati, Mercedes, Raine S., Eagles, David A., Cooper, Paul, Zdenek, Christina N., Fry, Bryan G., Hall, Donald W., Vetter, Irina and King, Glenn F. (2023). Horizontal gene transfer underlies the painful stings of asp caterpillars (Lepidoptera: Megalopygidae). Proceedings of the National Academy of Sciences, 120 (29) e2305871120, e2305871120. doi: 10.1073/pnas.2305871120
2023
Journal Article
Venom composition and bioactive RF-amide peptide toxins of the saddleback caterpillar, Acharia stimulea (Lepidoptera: Limacodidae)
Goudarzi, Mohaddeseh H., Eagles, David A., Lim, Junxian, Biggs, Kimberley A., Kotze, Andrew C., Ruffell, Angela P., Fairlie, David P., King, Glenn F. and Walker, Andrew A. (2023). Venom composition and bioactive RF-amide peptide toxins of the saddleback caterpillar, Acharia stimulea (Lepidoptera: Limacodidae). Biochemical Pharmacology, 213 115598, 1-11. doi: 10.1016/j.bcp.2023.115598
2023
Journal Article
The β3‐subunit modulates the effect of venom peptides ProTx‐II and OD1 on NaV 1.7 gating
Salvage, Samantha C., Rahman, Taufiq, Eagles, David A., Rees, Johanna S., King, Glenn F., Huang, Christopher L‐H. and Jackson, Antony P. (2023). The β3‐subunit modulates the effect of venom peptides ProTx‐II and OD1 on NaV 1.7 gating. Journal of Cellular Physiology, 238 (6), 1354-1367. doi: 10.1002/jcp.31018
2022
Journal Article
Cysteine-rich α-conotoxin SII displays novel interactions at the muscle nicotinic acetylcholine receptor
Wilhelm, Patrick, Luna-Ramirez, Karen, Chin, Yanni K.-Y., Dekan, Zoltan, Abraham, Nikita, Tae, Han-Shen, Chow, Chun Yuen, Eagles, David A., King, Glenn F., Lewis, Richard J., Adams, David J. and Alewood, Paul F. (2022). Cysteine-rich α-conotoxin SII displays novel interactions at the muscle nicotinic acetylcholine receptor. ACS Chemical Neuroscience, 13 (8), 1245-1250. doi: 10.1021/acschemneuro.1c00857
2022
Journal Article
A peptide toxin in ant venom mimics vertebrate EGF-like hormones to cause long-lasting hypersensitivity in mammals
Eagles, David A., Saez, Natalie J., Krishnarjuna, Bankala, Bradford, Julia J., Chin, Yanni K.-Y., Starobova, Hana, Mueller, Alexander, Reichelt, Melissa E., Undheim, Eivind A. B., Norton, Raymond S., Thomas, Walter G., Vetter, Irina, King, Glenn F. and Robinson, Samuel D. (2022). A peptide toxin in ant venom mimics vertebrate EGF-like hormones to cause long-lasting hypersensitivity in mammals. Proceedings of the National Academy of Sciences, 119 (7) e2112630119. doi: 10.1073/pnas.2112630119
2020
Journal Article
Fifteen years of NaV1.7 channels as an analgesic target: Why has excellent in vitro pharmacology not translated into in vivo analgesic efficacy?
Eagles, David A., Chow, Chun Yuen and King, Glenn F. (2020). Fifteen years of NaV1.7 channels as an analgesic target: Why has excellent in vitro pharmacology not translated into in vivo analgesic efficacy?. British Journal of Pharmacology, 179 (14) bph.15327, 3592-3611. doi: 10.1111/bph.15327
Supervision
Availability
- Dr David Eagles is:
- Available for supervision
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