Overview
Availability
- Dr Megan Soon is:
- Available for supervision
Qualifications
- Doctor of Philosophy of Biomedical Research, The University of Queensland
Works
Search Professor Megan Soon’s works on UQ eSpace
2025
Journal Article
Adjunctive ruxolitinib attenuates inflammation and enhances immunity in volunteers experimentally infected with Plasmodium falciparum
Webster, Rebecca, Oyong, Damian A., Llewellyn, Stacey, Abd-Rahman, Azrin N., Potter, Adam J., Mukhiya, Reena, Sahai, Nischal, Leelasena, Indika, Ujvary, Eniko, Mathison, Sue, Andrew, Dean W., Bukali, Luzia, de Labastida Rivera, Fabian, Engel, Jessica, Soon, Megan S. F., Frame, Teija, Hamelink, Julianne, Nalubega, Mayimuna, Dooley, Nicholas L., Loughland, Jessica R., Nguyen, Tran, Rosenberg-Hasson, Yael, Maysel-Auslender, Sofia, Sigal, Natalia, Foygel, Kira, Gower, Jeremy, Peters, Jenny, Woo, Ria, Amante, Fiona ... Boyle, Michelle J. (2025). Adjunctive ruxolitinib attenuates inflammation and enhances immunity in volunteers experimentally infected with Plasmodium falciparum. Science Translational Medicine, 17 (826) eaea2531, 1-15. doi: 10.1126/scitranslmed.aea2531
2025
Conference Publication
Enrichment of putative bacteria-reactive gut-derived IL-17+tissue resident memory helper T cells in arthritic ankles in the SKG mouse model of spondyloarthritis
Cai, Benjamin, Soon, Megan, Tuong, Zewen Kelvin, Morrison, Mark, Bergot, Anne-Sophie and Thomas, Ranjeny (2025). Enrichment of putative bacteria-reactive gut-derived IL-17+tissue resident memory helper T cells in arthritic ankles in the SKG mouse model of spondyloarthritis. ACR Convergence 2025, Chicago, IL, United States, 24 – 29 October 2025. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/art.43421
2025
Conference Publication
Expansion of viral-reactive CD8+T cell repertoire stratified by pathotype in new-onset ACPA plus rheumatoid arthritis
Coyle, Carl, Suwakulsiri, Wittaya, Andriessen, Lukas, Soon, Megan, Wehr, Pascale, Qureshi, Sumera, Altmann, Christopher, Small, Annabelle, Wong, Vincent, Cope, Andrew, Wei, Kevin, Nel, Hendrik, Wechalekar, Mihir and Thomas, Ranjeny (2025). Expansion of Viral-Reactive CD8+T cell Repertoire Stratified by Pathotype in New-onset ACPA plus Rheumatoid Arthritis. HOBOKEN: WILEY.
2025
Journal Article
Data standards for single‐cell RNA‐sequencing of paediatric cancer
Xu, Xiaohan, Saxon, John, Soon, Megan Sioe Fei, Lee, Colin Y. C. and Tuong, Zewen Kelvin (2025). Data standards for single‐cell RNA‐sequencing of paediatric cancer. Clinical & Translational Immunology, 14 (5) e70033, e70033-5. doi: 10.1002/cti2.70033
2024
Journal Article
CD4+ T cells display a spectrum of recall dynamics during re-infection with malaria parasites
Lee, Hyun Jae, Moreira, Marcela L., Li, Shihan, Asatsuma, Takahiro, Williams, Cameron G., Skinner, Oliver P., Asad, Saba, Bramhall, Michael, Jiang, Zhe, Liu, Zihan, Kerr, Ashlyn S., Engel, Jessica A., Soon, Megan S. F., Straube, Jasmin, Barrera, Irving, Murray, Evan, Chen, Fei, Nideffer, Jason, Jagannathan, Prasanna and Haque, Ashraful (2024). CD4+ T cells display a spectrum of recall dynamics during re-infection with malaria parasites. Nature Communications, 15 (1) 5497, 1-18. doi: 10.1038/s41467-024-49879-6
2024
Journal Article
Plasmodium infection induces phenotypic, clonal, and spatial diversity among differentiating CD4+ T cells (vol 43, 114317, 2024)
Williams, Cameron G., Moreira, Marcela L., Asatsuma, Takahiro, Lee, Hyun Jae, Li, Shihan, Burn, Thomas N., Barrera, Irving, Murray, Evan, Soon, Megan S. F., Engel, Jessica A., Khoury, David S., Le, Shirley, Wanrooy, Brooke J., Schienstock, Dominick, Alexandre, Yannick O., Skinner, Oliver P., Joseph, Rainon, Beattie, Lynette, Mueller, Scott N., Chen, Fei and Haque, Ashraful (2024). Plasmodium infection induces phenotypic, clonal, and spatial diversity among differentiating CD4+ T cells (vol 43, 114317, 2024). Cell Reports, 43 (9) 114754. doi: 10.1016/j.celrep.2024.114754
2024
Journal Article
Plasmodium infection induces phenotypic, clonal, and spatial diversity among differentiating CD4+T cells
Williams, Cameron G., Moreira, Marcela L., Asatsuma, Takahiro, Lee, Hyun Jae, Li, Shihan, Barrera, Irving, Murray, Evan, Soon, Megan S. F., Engel, Jessica A., Khoury, David S., Le, Shirley, Wanrooy, Brooke J., Schienstock, Dominick, Alexandre, Yannick O., Skinner, Oliver P., Joseph, Rainon, Beattie, Lynette, Mueller, Scott N., Chen, Fei and Haque, Ashraful (2024). Plasmodium infection induces phenotypic, clonal, and spatial diversity among differentiating CD4+T cells. Cell Reports, 43 (6) 114317, 1-28. doi: 10.1016/j.celrep.2024.114317
2024
Journal Article
Single-cell immune repertoire analysis
Irac, Sergio E., Soon, Megan Sioe Fei, Borcherding, Nicholas and Tuong, Zewen Kelvin (2024). Single-cell immune repertoire analysis. Nature Methods, 21 (5), 777-792. doi: 10.1038/s41592-024-02243-4
2024
Journal Article
Author Correction: The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation
Ng, Susanna S., De Labastida Rivera, Fabian, Yan, Juming, Corvino, Dillon, Das, Indrajit, Zhang, Ping, Kuns, Rachel, Chauhan, Shashi Bhushan, Hou, Jiajie, Li, Xian-Yang, Frame, Teija C. M., McEnroe, Benjamin A., Moore, Eilish, Na, Jinrui, Engel, Jessica A., Soon, Megan S. F., Singh, Bhawana, Kueh, Andrew J., Herold, Marco J., Montes de Oca, Marcela, Singh, Siddharth Sankar, Bunn, Patrick T., Aguilera, Amy Roman, Casey, Mika, Braun, Matthias, Ghazanfari, Nazanin, Wani, Shivangi, Wang, Yulin, Amante, Fiona H. ... Engwerda, Christian R. (2024). Author Correction: The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation. Nature Immunology, 25 (4), 716-716. doi: 10.1038/s41590-024-01770-8
2023
Journal Article
Single cell transcriptomics shows that malaria promotes unique regulatory responses across multiple immune cell subsets
Dooley, Nicholas L., Chabikwa, Tinashe G., Pava, Zuleima, Loughland, Jessica R., Hamelink, Julianne, Berry, Kiana, Andrew, Dean, Soon, Megan S. F., SheelaNair, Arya, Piera, Kim A., William, Timothy, Barber, Bridget E., Grigg, Matthew J., Engwerda, Christian R., Lopez, J. Alejandro, Anstey, Nicholas M. and Boyle, Michelle J. (2023). Single cell transcriptomics shows that malaria promotes unique regulatory responses across multiple immune cell subsets. Nature Communications, 14 (1) 7387, 1-22. doi: 10.1038/s41467-023-43181-7
2023
Journal Article
Systemic host inflammation induces stage-specific transcriptomic modification and slower maturation in malaria parasites
Lansink, Lianne I. M., Skinner, Oliver P., Engel, Jessica A., Lee, Hyun Jae, Soon, Megan S. F., Williams, Cameron G., SheelaNair, Arya, Pernold, Clara P. S., Laohamonthonkul, Pawat, Akter, Jasmin, Stoll, Thomas, Hill, Michelle M., Talman, Arthur M., Russell, Andrew, Lawniczak, Mara, Jia, Xiaoxiao, Chua, Brendon, Anderson, Dovile, Creek, Darren J., Davenport, Miles P., Khoury, David S. and Haque, Ashraful (2023). Systemic host inflammation induces stage-specific transcriptomic modification and slower maturation in malaria parasites. mBio, 14 (4). doi: 10.1128/mbio.01129-23
2021
Conference Publication
Studying lymphocyte differentiation in the spleen via spatial transcriptomics
Williams, Cameron Gerard, Engel, Jessica A., Soon, Megan S. F., Murray, Evan, Chen, Fei and Haque, Ashraful (2021). Studying lymphocyte differentiation in the spleen via spatial transcriptomics. Immunology 2021™ Meeting, Virtual, 10-15 May 2021. Cambridge, United Kingdom: Oxford University Press. doi: 10.4049/jimmunol.206.Supp.98.55
2021
Conference Publication
Exposure to host inflammation in vivo induces rapid transcriptomic change and impaired maturation in malaria parasites
Lansink, Lianne I. M., Engel, Jessica A., Lee, Hyun Jae, Soon, Megan S. F., Williams, Cameron G., Aogo, Rosemary A., Cromer, Deborah, Davenport, Miles P., Khoury, David S. and Haque, Ashraful (2021). Exposure to host inflammation in vivo induces rapid transcriptomic change and impaired maturation in malaria parasites. Immunology 2021™ Meeting, Virtual, 10-15 May 2021. Cary, NC USA: Oxford University Press. doi: 10.4049/jimmunol.206.Supp.99.22
2021
Other Outputs
Effector and memory CD4+ T cell development during experimental blood-stage malaria
Soon, Sioe Fei (2021). Effector and memory CD4+ T cell development during experimental blood-stage malaria. PhD Thesis, Faculty of Medicine, The University of Queensland. doi: 10.14264/6a26f34
2020
Journal Article
The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation
Ng, Susanna S., De Labastida Rivera, Fabian, Yan, Juming, Corvino, Dillon, Das, Indrajit, Zhang, Ping, Kuns, Rachel, Chauhan, Shashi Bhushan, Hou, Jiajie, Li, Xian-Yang, Frame, Teija C. M., McEnroe, Benjamin A., Moore, Eilish, Na, Jinrui, Engel, Jessica A., Soon, Megan S. F., Singh, Bhawana, Kueh, Andrew J., Herold, Marco J., Montes de Oca, Marcela, Singh, Siddharth Sankar, Bunn, Patrick T., Aguilera, Amy Roman, Casey, Mika, Braun, Matthias, Ghazanfari, Nazanin, Wani, Shivangi, Wang, Yulin, Amante, Fiona H. ... Engwerda, Christian R. (2020). The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation. Nature Immunology, 21 (10), 1205-1218. doi: 10.1038/s41590-020-0758-6
2020
Journal Article
Transcriptome dynamics of CD4+ T cells during malaria maps gradual transit from effector to memory
Soon, Megan S. F., Lee, Hyun Jae, Engel, Jessica A., Straube, Jasmin, Thomas, Bryce S., Pernold, Clara P. S., Clarke, Lachlan S., Laohamonthonkul, Pawat, Haldar, Rohit N., Williams, Cameron G., Lansink, Lianne I. M., Moreira, Marcela L., Bramhall, Michael, Koufariotis, Lambros T., Wood, Scott, Chen, Xi, James, Kylie R., Lönnberg, Tapio, Lane, Steven W., Belz, Gabrielle T., Engwerda, Christian R., Khoury, David S., Davenport, Miles P., Svensson, Valentine, Teichmann, Sarah A. and Haque, Ashraful (2020). Transcriptome dynamics of CD4+ T cells during malaria maps gradual transit from effector to memory. Nature Immunology, 21 (12), 1597-1610. doi: 10.1038/s41590-020-0800-8
2019
Journal Article
NKT cell-driven enhancement of antitumor immunity induced by Clec9a-targeted tailorable nanoemulsion
Lam, Pui Yeng, Kobayashi, Takumi, Soon, Megan, Zeng, Bijun, Dolcetti, Riccardo, Leggatt, Graham, Thomas, Ranjeny and Mattarollo, Stephen R. (2019). NKT cell-driven enhancement of antitumor immunity induced by Clec9a-targeted tailorable nanoemulsion. Cancer Immunology Research, 7 (6), 952-962. doi: 10.1158/2326-6066.cir-18-0650
2019
Journal Article
Plasmodium-specific antibodies block in vivo parasite growth without clearing infected red blood cells
Akter, Jasmin, Khoury, David S., Aogo, Rosemary, Lansink, Lianne I. M., SheelaNair, Arya, Thomas, Bryce S., Laohamonthonkul, Pawat, Pernold, Clara P. S., Dixon, Matthew W. A., Soon, Megan S. F., Fogg, Lily G., Engel, Jessica A., Elliott, Trish, Sebina, Ismail, James, Kylie R., Cromer, Deborah, Davenport, Miles P. and Haque, Ashraful (2019). Plasmodium-specific antibodies block in vivo parasite growth without clearing infected red blood cells. PLoS Pathogens, 15 (2) e1007599, e1007599. doi: 10.1371/journal.ppat.1007599
2018
Journal Article
Quantification of host-mediated parasite clearance during blood-stage Plasmodium infection and anti-malarial drug treatment in mice
Aogo, Rosemary A., Khoury, David S., Cromer, Deborah, Elliott, Trish, Akter, Jasmin, Fogg, Lily G., Nair, Arya Sheela, Liligeto, Urijah N., Soon, Megan S. F., Thomas, Bryce S., Pernold, Clara P. S., Romanczuk, Aleksandra S., Laohamonthonkul, Pawat, Haque, Ashraful and Davenport, Miles P. (2018). Quantification of host-mediated parasite clearance during blood-stage Plasmodium infection and anti-malarial drug treatment in mice. International Journal for Parasitology, 48 (12), 903-913. doi: 10.1016/j.ijpara.2018.05.010
2018
Journal Article
Therapeutic vaccination with 4–1BB co-stimulation eradicates mouse acute myeloid leukemia
Kerage, Daniel, Soon, Megan S. F., Doff, Brianna L., Kobayashi, Takumi, Nissen, Michael D., Lam, Pui Yeng, Leggatt, Graham R. and Mattarollo, Stephen R. (2018). Therapeutic vaccination with 4–1BB co-stimulation eradicates mouse acute myeloid leukemia. OncoImmunology, 7 (10) e1486952, 1-10. doi: 10.1080/2162402x.2018.1486952
Supervision
Availability
- Dr Megan Soon is:
- Available for supervision
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