Overview
Availability
- Dr Qian Guo is:
- Available for supervision
Qualifications
- Doctor of Philosophy of Biochemistry and Molecular Biology, The University of Queensland
- Doctor of Philosophy of Molecular Biology, The University of Queensland
Works
Search Professor Qian Guo’s works on UQ eSpace
2025
Journal Article
Mapping of endosomal proximity proteomes reveals Retromer as a hub for RAB GTPase regulation
Antón-Plágaro, Carlos, Chen, Kai-en, Guo, Qian, Liu, Meihan, Evans, Ashley J., Lewis, Philip A., Heesom, Kate J., Wilkinson, Kevin A., Collins, Brett M. and Cullen, Peter J. (2025). Mapping of endosomal proximity proteomes reveals Retromer as a hub for RAB GTPase regulation. Nature Communications, 16 (1) 6990, 1-23. doi: 10.1038/s41467-025-61802-1
2025
Journal Article
Identification of a VPS29 isoform with restricted association to Retriever and Retromer accessory proteins through autoinhibition
Daly, James L., Chen, Kai-en, Butkovič, Rebeka, Guo, Qian, Healy, Michael D., Pennink, Eva, Gamble-Strutt, Georgia, Higham, Zara, Moody, Edmund R. R., Lewis, Philip A., Heesom, Kate J., Williams, Tom A., McMillan, Kirsty J., Collins, Brett M. and Cullen, Peter J. (2025). Identification of a VPS29 isoform with restricted association to Retriever and Retromer accessory proteins through autoinhibition. Proceedings of the National Academy of Sciences, 122 (27) e2501111122, e2501111122-27. doi: 10.1073/pnas.2501111122
2025
Journal Article
Cavin1 binding nanobodies reveal structural flexibility and regulated interactions of the N-terminal coiled-coil domain
Gao, Ya, Tillu, Vikas A., Wu, Yeping, Rae, James, Hall, Thomas E., Chen, Kai-en, Weeratunga, Saroja, Guo, Qian, Livingstone, Emma, Tham, Wai-Hong, Parton, Robert G. and Collins, Brett M. (2025). Cavin1 binding nanobodies reveal structural flexibility and regulated interactions of the N-terminal coiled-coil domain. Journal of Cell Science, 138 (8) 263756. doi: 10.1242/jcs.263756
2025
Journal Article
Molecular basis for the assembly of the Vps5-Vps17 SNX-BAR proteins with Retromer
Chen, Kai-En, Tillu, Vikas A., Gopaldass, Navin, Chowdhury, Sudeshna Roy, Leneva, Natalya, Kovtun, Oleksiy, Ruan, Juanfang, Guo, Qian, Ariotti, Nicholas, Mayer, Andreas and Collins, Brett M. (2025). Molecular basis for the assembly of the Vps5-Vps17 SNX-BAR proteins with Retromer. Nature Communications, 16 (1) 3568, 3568. doi: 10.1038/s41467-025-58846-8
2024
Journal Article
Structural basis for coupling of the WASH subunit FAM21 with the endosomal SNX27–Retromer complex
Guo, Qian, Chen, Kai-en, Gimenez-Andres, Manuel, Jellett, Adam P., Gao, Ya, Simonetti, Boris, Liu, Meihan, Danson, Chris M., Heesom, Kate J., Cullen, Peter J. and Collins, Brett M. (2024). Structural basis for coupling of the WASH subunit FAM21 with the endosomal SNX27–Retromer complex. Proceedings of the National Academy of Sciences, 121 (33) e2405041121, 1-12. doi: 10.1073/pnas.2405041121
2023
Other Outputs
Structural characterisation of endosomal trafficking protein sorting nexin 27
Guo, Qian (2023). Structural characterisation of endosomal trafficking protein sorting nexin 27. PhD Thesis, Institute for Molecular Bioscience, The University of Queensland. doi: 10.14264/f0f0d72
2023
Conference Publication
Structural basis for coupling of the WASH subunit Fam21 with the SNX27–retromer endosomal trafficking complex
Guo, Qian, Chen, Kai-En, Simonetti, Boris, Gimenez-Andres, Manuel, Cullen, Peter J. and Collins, Brett M. (2023). Structural basis for coupling of the WASH subunit Fam21 with the SNX27–retromer endosomal trafficking complex. XXVI IUCr Congress, Melbourne, VIC, Australia, 22-29 August 2023. Hoboken, NJ, United States: Wiley-Blackwell. doi: 10.1107/s2053273323086837
2023
Conference Publication
Discovery and structural characterization of novel nanobodies targeting the Cavin1 complex essential for forming caveola membrane vesicles
Gao, Ya, Tillu, Vikas A., Wu, Yeping, Rae, James, Hall, Thomas E., Chen, Kai-En, Weeratunga, Saroja, Guo, Qian, Parton, Robert G. and Collins, Brett M. (2023). Discovery and structural characterization of novel nanobodies targeting the Cavin1 complex essential for forming caveola membrane vesicles. XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s2053273323086825
2023
Conference Publication
Discovery and structural characterization of novel nanobodies targeting the Cavin1 complex essential for forming caveola membrane vesicles
Gao, Ya, Tillu, Vikas A., Wu, Yeping, Rae, James, Hall, Thomas E., Chen, Kai-en, Weeratunga, Saroja, Guo, Qian, Parton, Robert G. and Collins, Brett M. (2023). Discovery and structural characterization of novel nanobodies targeting the Cavin1 complex essential for forming caveola membrane vesicles. XXVI IUCr Congress, Melbourne, VIC, Australia, 22-29 August 2023. Hoboken, NJ, United States: Wiley-Blackwell Publishing. doi: 10.1107/S2053273323086825
2022
Journal Article
SNX27–Retromer directly binds ESCPE-1 to transfer cargo proteins during endosomal recycling
Simonetti, Boris, Guo, Qian, Giménez-Andrés, Manuel, Chen, Kai-En, Moody, Edmund R. R., Evans, Ashley J., Chandra, Mintu, Danson, Chris M., Williams, Tom A., Collins, Brett M. and Cullen, Peter J. (2022). SNX27–Retromer directly binds ESCPE-1 to transfer cargo proteins during endosomal recycling. PLoS Biology, 20 (4) e3001601, e3001601. doi: 10.1371/journal.pbio.3001601
2021
Journal Article
De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex
Chen, Kai-En, Guo, Qian, Hill, Timothy A., Cui, Yi, Kendall, Amy K., Yang, Zhe, Hall, Ryan J., Healy, Michael D., Sacharz, Joanna, Norwood, Suzanne J., Fonseka, Sachini, Xie, Boyang, Reid, Robert C., Leneva, Natalya, Parton, Robert G., Ghai, Rajesh, Stroud, David A., Fairlie, David P, Suga, Hiroaki, Jackson, Lauren P., Teasdale, Rohan D., Passioura, Toby and Collins, Brett M. (2021). De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex. Science Advances, 7 (49) eabg4007, eabg4007. doi: 10.1126/sciadv.abg4007
2021
Journal Article
Community-wide experimental evaluation of the PROSS stability-design method
Peleg, Yoav, Vincentelli, Renaud, Collins, Brett M., Chen, Kai-En, Livingstone, Emma K., Weeratunga, Saroja, Leneva, Natalya, Guo, Qian, Remans, Kim, Perez, Kathryn, Bjerga, Gro E K, Larsen, Øivind, Vaněk, Ondřej, Skořepa, Ondřej, Jacquemin, Sophie, Poterszman, Arnaud, Kjær, Svend, Christodoulou, Evangelos, Albeck, Shira, Dym, Orly, Ainbinder, Elena, Unger, Tamar, Schuetz, Anja, Matthes, Susann, Bader, Michael, de Marco, Ario, Storici, Paola, Semrau, Marta S., Stolt-Bergner, Peggy ... Fleishman, Sarel J. (2021). Community-wide experimental evaluation of the PROSS stability-design method. Journal of Molecular Biology, 433 (13) 166964, 166964. doi: 10.1016/j.jmb.2021.166964
Supervision
Availability
- Dr Qian Guo is:
- Available for supervision
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