Overview
Background
My current appointment is Director of Kidney Services at Redland Hospitals in Metro South, Brisbane, where I practice as a senior consultant nephrologist.
My research interests are varied and include post-transplant anaemia and iron metabolism, and novel measures of iron status such as hepcidin; improving dialysis outcomes though the implementation of evidence-based guidelines; kidney disease due to thrombotic microangiopathy (particularly aHUS) and the role of inhibitors of the complement system in kidney disease; and the use of honey to prevent infections in dialysis patients.
I am committed to teaching medical students and young nephrologists, and am actively involved in medical education at all levels.
Availability
- Professor David Mudge is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor of Medicine, of Surgery and of Obstetrics, The University of Queensland
- Doctoral (Research) of Medicine, The University of Queensland
Research impacts
The impact of my research in peritoneal dialysis has been a significant improvement in PD-related infection rates in Australia, which until a few years ago were worse than many other countries in the world. Through a variety of initiatives including a project aiming to improve the use of evidence-based guidelines in clinical practice, we have seen a significant improvement in PD-related infections (particularly peritonitis but also exit-site infections), one of the most significant contributors to peritoneal dialysis technique failure.
In kidney transplantation my research has helped to clarify the role of immune suppressing medications on iron availability and anaemia and has looked at novel ways of measuring iron status in patients with kidney disease as well as better ways of enhancing iron stores in these patients.
Works
Search Professor David Mudge’s works on UQ eSpace
2024
Journal Article
The stuck haemodialysis catheter—a case report of a rare but dreaded complication following kidney transplantation
Burnett, Cameron, Chandler, S., Jegatheesan, D., Pearch, B., Viecelli, A. and Mudge, D. W. (2024). The stuck haemodialysis catheter—a case report of a rare but dreaded complication following kidney transplantation. BMC Nephrology, 25 (1) 104, 1-4. doi: 10.1186/s12882-024-03507-z
2024
Journal Article
Acute kidney injury and tacrolimus toxicity in a kidney transplant recipient treated with nirmaltrevir/ritonavir: a case report
Rycen, Jack, Jefferis, Julia and Mudge, David (2024). Acute kidney injury and tacrolimus toxicity in a kidney transplant recipient treated with nirmaltrevir/ritonavir: a case report. Journal of Medical Case Reports, 18 (1) 629, 1-5. doi: 10.1186/s13256-024-04990-6
2024
Conference Publication
A Journey through Low-Energy Diets in Adults with Kidney Disease: Insights from the Slow-CKD Feasibility Study
Conley, Marguerite M., Scholes-Robertson, Nicole Jane, Cunningham, Soraya Lynne, Hepburn, Kirsten S., Mayr, Hannah L., Mudge, David William, Holland, Justin James, Johnson, David W., Viecelli, Andrea K. and MacLaughlin, Helen L. (2024). A Journey through Low-Energy Diets in Adults with Kidney Disease: Insights from the Slow-CKD Feasibility Study. Kidney Week, San Diego, CA United States, 24-27 October 2024. Philadelphia, PA United States: Wolters Kluwer. doi: 10.1681/asn.2024y1jferhx
2024
Conference Publication
Exploring the Effects of Low-Energy Diets on Risk Factors and Markers of Kidney Disease: Findings from the Slowing Kidney Disease with Weight-Loss Feasibility Study
Conley, Marguerite M., Hepburn, Kirsten S., Mayr, Hannah L., Mudge, David William, Holland, Justin James, Viecelli, Andrea K., Johnson, David W. and MacLaughlin, Helen L. (2024). Exploring the Effects of Low-Energy Diets on Risk Factors and Markers of Kidney Disease: Findings from the Slowing Kidney Disease with Weight-Loss Feasibility Study. Kidney Week, San Diego, CA United States, 24-27 October 2024. Philadelphia, PA United States: Wolters Kluwer. doi: 10.1681/asn.2024t6bhp64d
2024
Journal Article
Risk of relapse of antineutrophil cytoplasmic antibody–associated vasculitis in a randomized controlled trial of plasma exchange and glucocorticoids
Junek, Mats L., Merkel, Peter A., Vilayur, Eswari, Wald, Ron, Khalidi, Nader, Jayne, David, Walsh, Michael, Paizis, Kathy, Reidlinger, Donna (PEXIVAS Investigators), Morrish, Alicia, Badve, Sunil V, Pascoe, Elaine (PEXIVAS Investigators), Paul-Brent, Peta-Anne, Robison, Laura, Valks, Andrea, Walters, Giles, Jardine, Meg, Milton, Caroline, Ibraham, Abu, Siva, Brian, Desmond, Michael, Perkovic, Vlado, Kurtkoti, Jadadeesh, Vilayur, Eswari, Cass, Alan, Summers, Shaun, Brown, Fiona, Ryan, Jessica, Kerr, Peter ... PEXIVAS Investigators (2024). Risk of relapse of antineutrophil cytoplasmic antibody–associated vasculitis in a randomized controlled trial of plasma exchange and glucocorticoids. Arthritis and Rheumatology, 76 (9), 1431-1438. doi: 10.1002/art.42843
2024
Journal Article
Alveolar hemorrhage in antineutrophil cytoplasmic antibody-associated vasculitis results of an international randomized controlled trial (PEXIVAS)
Fussner, Lynn A., Flores-Suárez, Luis Felipe, Cartin-Ceba, Rodrigo, Specks, Ulrich, Cox, P. Gerard, Jayne, David R.W., Merkel, Peter A., Walsh, Michael, Paizis, Kathy, Walters, Giles, Jardine, Meg, Milton, Caroline, Ibraham, Abu, Siva, Brian, Desmond, Michael, Perkovic, Vlado, Kurtkoti, Jadadeesh, Vilayur, Eswari, Cass, Alan, Summers, Shaun, Brown, Fiona, Ryan, Jessica, Kerr, Peter, Noble, Euan, Luxton, Grant, Mudge, David W., Hawley, Carmel, Johnson, David W., Peh, Chen Au ... PEXIVAS Investigators (2024). Alveolar hemorrhage in antineutrophil cytoplasmic antibody-associated vasculitis results of an international randomized controlled trial (PEXIVAS). American Journal of Respiratory and Critical Care Medicine, 209 (9), 1141-1151. doi: 10.1164/rccm.202308-1426OC
2024
Conference Publication
Slowing kidney disease with weight loss: a randomised controlled feasibility study (SLOW-CKD Feasibility Study)
Conley, Marguerite, Hepburn, Kirsten, Mayr, Hannah, Mudge, David, Holland, Justin, Tonges, Tammy, Modderman, Richard, Gerzina, Sally, Johnson, David W., Viecelli, Andrea and Maclaughlin, Helen (2024). Slowing kidney disease with weight loss: a randomised controlled feasibility study (SLOW-CKD Feasibility Study). 61st ERA Congress, Stockholm, Sweden, 23-26 May 2024. OXFORD: Oxford University Press. doi: 10.1093/ndt/gfae069.730
2023
Journal Article
The impact of treatment with avacopan on health-related quality of life in antineutrophil cytoplasmic antibody-associated vasculitis: a post-hoc analysis of data from the ADVOCATE trial
Strand, Vibeke, Jayne, David R W, Horomanski, Audra, Yue, Huibin, Bekker, Pirow, Merkel, Peter A, Au Peh, Chen, Chakera, Aron, Cooper, Bruce, Kurtkoti, Jagadeesh, Langguth, Daman, Levidiotis, Vicki, Luxton, Grant, Mount, Peter, Mudge, David, Noble, Euan, Phoon, Richard, Ranganathan, Dwarakanathan, Ritchie, Angus, Ryan, Jessica, Suranyi, Michael, Rosenkranz, Alexander, Lhotta, Karl, Kronbichler, Andreas, Demoulin, Nathalie, Bovy, Christophe, Hellemans, Rachel, Hougardy, Jean-Michel, Sprangers, Ben ... on behalf of the ADVOCATE Study Group (2023). The impact of treatment with avacopan on health-related quality of life in antineutrophil cytoplasmic antibody-associated vasculitis: a post-hoc analysis of data from the ADVOCATE trial. The Lancet Rheumatology, 5 (8), e451-e460. doi: 10.1016/S2665-9913(23)00092-9
2023
Journal Article
Renal recovery for patients with ANCA-associated vasculitis and low eGFR in the ADVOCATE trial of avacopan
Cortazar, Frank B., Niles, John L., Jayne, David R.W., Merkel, Peter A., Bruchfeld, Annette, Yue, Huibin, Schall, Thomas J., Bekker, Pirow, Peh, C. Au, Chakera, A., Cooper, B., Kurtkoti, J., Langguth, D., Levidiotis, V., Luxton, G., Mount, P., Mudge, D., Noble, E., Phoon, R., Ranganathan, D., Ritchie, A., Ryan, J., Suranyi, M., Rosenkranz, A., Lhotta, K., Kronbichler, A., Demoulin, N., Bovy, C., Hellemans, R. ... Wasko, M. Chester (2023). Renal recovery for patients with ANCA-associated vasculitis and low eGFR in the ADVOCATE trial of avacopan. Kidney International Reports, 8 (4), 860-870. doi: 10.1016/j.ekir.2023.01.039
2022
Book Chapter
Peritoneal dialysis: infections
Nguyen, Thu T., Palmer, Suetonia C., Cho, Yeoungjee, Mudge, David W., Strippoli, Giovanni F. M., Craig, Jonathan C., Johnson, David W. and Htay, Htay (2022). Peritoneal dialysis: infections. Evidence-based nephrology. (pp. 138-155) edited by Jonathan C. Craig, Donald A. Molony and Giovanni F. M. Strippoli. Hoboken, NJ USA: John Wiley & Sons. doi: 10.1002/9781119105954.ch48
2022
Journal Article
The ACTION (AT1R and CCR2 targets for inflammatory nephrosis) program in focal segmental glomerulosclerosis : SA-PO708
Roger, Simon D., Mudge, David W., Nelson, Craig L., Wong, Muh Geot, Shepherd, Robert, Smith, Alisha J., Packham, David K. and ACTION-FSGS (2022). The ACTION (AT1R and CCR2 targets for inflammatory nephrosis) program in focal segmental glomerulosclerosis : SA-PO708. Journal of the American Society of Nephrology, 33 (11S), 798-798. doi: 10.1681/asn.20223311s1798b
2022
Journal Article
Human T-cell leukaemia virus type 1 and Adult T-cell leukaemia/lymphoma in Queensland, Australia: a retrospective cross-sectional study
Martin, Fabiola, Gilks, Charles F., Gibb, Robert, Jenkins, Alana, Protani, Melinda, Francis, Fleur, Redmond, Andrew M., Neilsen, Graham, Mudge, David, Wolley, Martin, Binotto, Enzo, Norton, Robert, Nimmo, Graeme R. and Heney, Claire (2022). Human T-cell leukaemia virus type 1 and Adult T-cell leukaemia/lymphoma in Queensland, Australia: a retrospective cross-sectional study. Sexually Transmitted Infections, 99 (1), 50-52. doi: 10.1136/sextrans-2021-055241
2021
Journal Article
Utility of ‘back-up’ arterio-venous fistulae in patients on peritoneal dialysis and use of haemodialysis catheters
Rao, Nitesh N., Borlace, Monique, Taylor, Rebecca, Matthew, Yvonne, Johnson, David W., Jaffrey, Lauren, Mudge, David W. and Bannister, Kym (2021). Utility of ‘back-up’ arterio-venous fistulae in patients on peritoneal dialysis and use of haemodialysis catheters. Internal Medicine Journal, 51 (7), 1106-1110. doi: 10.1111/imj.14875
2021
Journal Article
Altered dietary salt intake for people with chronic kidney disease
McMahon, Emma J, Campbell, Katrina L, Bauer, Judith D, Mudge, David W and Kelly, Jaimon T (2021). Altered dietary salt intake for people with chronic kidney disease. Cochrane Database of Systematic Reviews, 2021 (6) CD010070, CD010070. doi: 10.1002/14651858.CD010070.pub3
2020
Journal Article
Methamphetamine intoxication and acute kidney injury: a prospective observational case series
Isoardi, Katherine Z., Mudge, David W., Harris, Keith, Dimeski, Goce and Buckley, Nicholas A. (2020). Methamphetamine intoxication and acute kidney injury: a prospective observational case series. Nephrology, 25 (10) nep.13762, 758-764. doi: 10.1111/nep.13762
2020
Journal Article
Baseline characteristics of patients with atypical haemolytic uraemic syndrome (aHUS): the Australian cohort in a global aHUS registry
Soraru, Jacqueline, Isbel, Nicole, Wong, Germaine, Coates, Patrick Toby, Mantha, Murty, Abraham, Abu, Juneja, Rajiv, Hsu, Danny, Brown, Fiona, Bose, Bhadran, Mudge, David, Carroll, Robert, Kausman, Joshua, Hughes, Peter, Barbour, Thomas, Durkan, Anne, Mount, Peter, Lee, Darren, Larkins, Nicholas, Ranganathan, Dwarakanathan and Lim, Wai H (2020). Baseline characteristics of patients with atypical haemolytic uraemic syndrome (aHUS): the Australian cohort in a global aHUS registry. Nephrology, 25 (9) nep.13722, 683-690. doi: 10.1111/nep.13722
2018
Journal Article
Disseminated cryptococcosis presenting initially as lower limb cellulitis in a renal transplant recipient - a case report
Chakradeo, Katrina, Paul Chia, Y. Y., Liu, Cheng, Mudge, David W. and De Silva, Janath (2018). Disseminated cryptococcosis presenting initially as lower limb cellulitis in a renal transplant recipient - a case report. BMC Nephrology, 19 (1) 18, 18. doi: 10.1186/s12882-018-0815-7
2017
Journal Article
Progression of arterial stiffness is associated with changes in bone mineral markers in advanced CKD
Krishnasamy, Rathika, Tan, Sven-Jean, Hawley, Carmel M., Johnson, David W., Stanton, Tony, Lee, Kevin, Mudge, David W., Campbell, Scott, Elder, Grahame J., Toussaint, Nigel D. and Isbel, Nicole M. (2017). Progression of arterial stiffness is associated with changes in bone mineral markers in advanced CKD. BMC Nephrology, 18 (1) 281, 281. doi: 10.1186/s12882-017-0705-4
2017
Journal Article
Endovascular Proximal Forearm Arteriovenous Fistula for Hemodialysis Access: Results of the Prospective, Multicenter Novel Endovascular Access Trial (NEAT)
Lok, Charmaine E., Rajan, Dheeraj K., Clement, Jason, Dipchand, Mercedeh, Moist, Louise, Sasal, Joanna, on behalf of the NEAT Investigators, Mudge, David, Isbel, Nicole Maree, Hawley, Carmel M. and Johnson, David W (2017). Endovascular Proximal Forearm Arteriovenous Fistula for Hemodialysis Access: Results of the Prospective, Multicenter Novel Endovascular Access Trial (NEAT). American Journal of Kidney Diseases, 70 (4), 486-497. doi: 10.1053/j.ajkd.2017.03.026
2017
Journal Article
Antimicrobial agents for preventing peritonitis in peritoneal dialysis patients
Campbell, Denise, Mudge, David W., Craig, Jonathan C, Johnson, David W., Tong, Allison and Strippoli, Giovanni Fm (2017). Antimicrobial agents for preventing peritonitis in peritoneal dialysis patients. The Cochrane database of systematic reviews, 4 (4) CD004679, CD004679. doi: 10.1002/14651858.CD004679.pub3
Funding
Past funding
Supervision
Availability
- Professor David Mudge is:
- Available for supervision
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Supervision history
Completed supervision
-
2019
Master Philosophy
Very early acute rejection in an Australian and New Zealand kidney transplant population
Principal Advisor
Other advisors: Professor David Johnson, Professor Carmel Hawley, Associate Professor Yeoung Jee Cho, Associate Professor Ross Francis
-
2015
Doctor Philosophy
Inflammation in Peritoneal Dialysis: Investigating the Roles of Biocompatible Solutions and Biological Markers
Associate Advisor
Other advisors: Professor David Johnson, Professor Carmel Hawley
Media
Enquiries
Contact Professor David Mudge directly for media enquiries about:
- Anaemia
- Chronic kidney disease
- Iron regulation
- Kidney disease
- Kidney transplantation
- Organ transplant - kidney
- Transplant - kidney
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