
Overview
Background
Organic Chemistry
PhD
Availability
- Dr Huy Hoang is:
- Available for supervision
Fields of research
Qualifications
- Bachelor (Honours) of Science (Advanced), The University of Queensland
- Doctor of Philosophy, The University of Queensland
Works
Search Professor Huy Hoang’s works on UQ eSpace
2024
Journal Article
Potent immunomodulators developed from an unstable bacterial metabolite of vitamin B2 biosynthesis
Mak, Jeffrey Y. W., Rivero, Ryan J. D., Hoang, Huy N., Lim, Xin Yi, Deng, Jieru, McWilliam, Hamish E. G., Villadangos, Jose A., McCluskey, James, Corbett, Alexandra J. and Fairlie, David P. (2024). Potent immunomodulators developed from an unstable bacterial metabolite of vitamin B2 biosynthesis. Angewandte Chemie (International Edition), 63 (31) e202400632, e202400632. doi: 10.1002/anie.202400632
2023
Journal Article
N-(2-Aminophenyl)-benzamide Inhibitors of Class I HDAC Enzymes with Antiproliferative and Antifibrotic Activity
Gerokonstantis, Dimitrios Triantafyllos, Mantzourani, Christiana, Gkikas, Dimitrios, Wu, Kai-Chen, Hoang, Huy N., Triandafillidi, Ierasia, Barbayianni, Ilianna, Kanellopoulou, Paraskevi, Kokotos, Alexandros C., Moutevelis-Minakakis, Panagiota, Aidinis, Vassilis, Politis, Panagiotis K., Fairlie, David P. and Kokotos, George (2023). N-(2-Aminophenyl)-benzamide Inhibitors of Class I HDAC Enzymes with Antiproliferative and Antifibrotic Activity. Journal of Medicinal Chemistry, 66 (20), 1-20. doi: 10.1021/acs.jmedchem.3c01422
2023
Journal Article
Talarolides Revisited: Cyclic Heptapeptides from an Australian Marine Tunicate-Associated Fungus, Talaromyces sp. CMB-TU011
Salim, Angela A., Hussein, Waleed M., Dewapriya, Pradeep, Hoang, Huy N., Zhou, Yahao, Samarasekera, Kaumadi, Khalil, Zeinab G., Fairlie, David P. and Capon, Robert J. (2023). Talarolides Revisited: Cyclic Heptapeptides from an Australian Marine Tunicate-Associated Fungus, Talaromyces sp. CMB-TU011. Marine Drugs, 21 (9) 487, 1-17. doi: 10.3390/md21090487
2022
Journal Article
Helical structure in cyclic peptides: effect of N-methyl amides versus esters
Wu, Chongyang, Hoang, Huy N., Hill, Timothy A., Lim, Junxian, Kok, W. Mei, Akondi, Kalyani, Liu, Ligong and Fairlie, David P. (2022). Helical structure in cyclic peptides: effect of N-methyl amides versus esters. Chemical Communications, 58 (89), 12475-12478. doi: 10.1039/d2cc05092g
2022
Journal Article
Tuning electrostatic and hydrophobic surfaces of aromatic rings to enhance membrane association and cell uptake of peptides
de Araujo, Aline Dantes, Hoang, Huy N., Lim, Junxian, Mak, Jeffrey and Fairlie, David P. (2022). Tuning electrostatic and hydrophobic surfaces of aromatic rings to enhance membrane association and cell uptake of peptides. Angewandte Chemie International Edition, 61 (29) e202203995, e202203995. doi: 10.1002/anie.202203995
2022
Journal Article
Landscaping macrocyclic peptides: stapling hDM2-binding peptides for helicity, protein affinity, proteolytic stability and cell uptake
de Araujo, Aline D., Lim, Junxian, Wu, Kai-Chen, Hoang, Huy N., Nguyen, Huy T. and Fairlie, David P. (2022). Landscaping macrocyclic peptides: stapling hDM2-binding peptides for helicity, protein affinity, proteolytic stability and cell uptake. RSC Chemical Biology, 3 (7), 895-904. doi: 10.1039/d1cb00231g
2022
Journal Article
Tuning Electrostatic and Hydrophobic Surfaces of Aromatic Rings to Enhance Membrane Association and Cell Uptake of Peptides
de Araujo, Aline D., Hoang, Huy N., Lim, Junxian, Mak, Jeffrey Y. W. and Fairlie, David P. (2022). Tuning Electrostatic and Hydrophobic Surfaces of Aromatic Rings to Enhance Membrane Association and Cell Uptake of Peptides. Angewandte Chemie, 134 (29). doi: 10.1002/ange.202203995
2021
Journal Article
Connecting hydrophobic surfaces in cyclic peptides increases membrane permeability
Hoang, Huy N., Hill, Timothy A. and Fairlie, David P. (2021). Connecting hydrophobic surfaces in cyclic peptides increases membrane permeability. Angewandte Chemie International Edition, 60 (15), 8385-8390. doi: 10.1002/anie.202012643
2020
Journal Article
High cell permeability does not predict oral bioavailability for analogues of cyclic heptapeptide sanguinamide A
Nielsen, Daniel S., Lohman, Rink-Jan, Hoang, Huy N., Fairlie, David P. and Hill, Timothy A. (2020). High cell permeability does not predict oral bioavailability for analogues of cyclic heptapeptide sanguinamide A. Australian Journal of Chemistry, 73 (4), 344-351. doi: 10.1071/ch19479
2020
Journal Article
Correction: Twists or turns: stabilising alpha vs. beta turns in tetrapeptides
Hoang, Huy N., Hill, Timothy A., Ruiz-Gómez, Gloria, Diness, Frederik, Mason, Jody M., Wu, Chongyang, Abbenante, Giovanni, Shepherd, Nicholas E. and Fairlie, David P. (2020). Correction: Twists or turns: stabilising alpha vs. beta turns in tetrapeptides. Chemical Science, 11 (28), 7511-7511. doi: 10.1039/d0sc90138e
2019
Journal Article
A novel long‐range n to π* interaction secures the smallest known α‐helix in water
Hoang, Huy N., Wu, Chongyang, Hill, Timothy A., Dantas de Araujo, Aline, Bernhardt, Paul V., Liu, Ligong and Fairlie, David P. (2019). A novel long‐range n to π* interaction secures the smallest known α‐helix in water. Angewandte Chemie, 131 (52), 19049-19053. doi: 10.1002/ange.201911277
2019
Journal Article
A novel long-range n to π* interaction secures the smallest known α-helix in water
Hoang, Huy N., Wu, Chongyang, Hill, Timothy A., Dantas de Araujo, Aline, Bernhardt, Paul V., Liu, Ligong and Fairlie, David P. (2019). A novel long-range n to π* interaction secures the smallest known α-helix in water. Angewandte Chemie International Edition, 58 (52) ange.201911277, 18873-18877. doi: 10.1002/anie.201911277
2019
Journal Article
Mirror image pairs of cyclic hexapeptides have different oral bioavailabilities and metabolic stabilities
Lohman, Rink-Jan, Nielsen, Daniel S., Kok, W. Mei, Hoang, Huy N., Hill, Timothy A. and Fairlie, David P. (2019). Mirror image pairs of cyclic hexapeptides have different oral bioavailabilities and metabolic stabilities. Chemical Communications, 55 (89), 13362-13365. doi: 10.1039/c9cc06234c
2019
Journal Article
Structure-activity relationships of wollamide cyclic hexapeptides with activity against drug-resistant and intracellular
Khalil, Zeinab G., Hill, Timothy A., De Leon Rodriguez, Luis M., Lohman, Rink-Jan, Hoang, Huy N., Reiling, Norbert, Hillemann, Doris, Brimble, Margaret A., Fairlie, David, Blumenthal, Antje and Capon, Robert J. (2019). Structure-activity relationships of wollamide cyclic hexapeptides with activity against drug-resistant and intracellular. Antimicrobial Agents and Chemotherapy, 63 (3) e01773-18. doi: 10.1128/AAC.01773-18
2019
Journal Article
Twists or turns: stabilising alpha vs. beta turns in tetrapeptides
Hoang, Huy N., Hill, Timothy A., Ruiz-Gómez, Gloria, Diness, Frederik, Mason, Jody M., Wu, Chongyang, Abbenante, Giovanni, Shepherd, Nicholas E. and Fairlie, David P. (2019). Twists or turns: stabilising alpha vs. beta turns in tetrapeptides. Chemical Science, 10 (45), 10595-10600. doi: 10.1039/c9sc04153b
2018
Journal Article
Glucuronic acid as a helix-inducing linker in short peptides
Wu, Chongyang, Hoang, Huy N, Liu, Ligong and Fairlie, David P (2018). Glucuronic acid as a helix-inducing linker in short peptides. Chemical Communications, 54 (17), 2162-2165. doi: 10.1039/c7cc09785a
2018
Journal Article
Contiguous hydrophobic and charged surface patches in short helix-constrained peptides drive cell permeability
Perry, Samuel R, Hill, Timothy A, de Araujo, Aline D, Hoang, Huy N and Fairlie, David P (2018). Contiguous hydrophobic and charged surface patches in short helix-constrained peptides drive cell permeability. Organic & biomolecular chemistry, 16 (3), 367-371. doi: 10.1039/c7ob02952g
2017
Journal Article
Alpha helix nucleation by a simple cyclic tetrapeptide
Hoang, Huy N., Wu, Chongyang, Beyer, Renee L., Hill, Timothy A. and Fairlie, David P. (2017). Alpha helix nucleation by a simple cyclic tetrapeptide. Australian Journal of Chemistry, 70 (2), 213-219. doi: 10.1071/CH16591
2017
Journal Article
Helixconstraints and amino acid substitution in GLP-1 increase cAMP and insulin secretion but not beta-arrestin 2 signaling
Plisson, Fabien, Hill, Timothy A., Mitchell, Justin M., Hoang, Huy N., de Araujo, Aline D., Xu, Weijun, Cotterell, Adam, Edmonds, David J., Stanton, Robert V., Derksen, David R., Loria, Paula M., Griffith, David A., Price, David A., Liras, Spiros and Fairlie, David P. (2017). Helixconstraints and amino acid substitution in GLP-1 increase cAMP and insulin secretion but not beta-arrestin 2 signaling. European Journal of Medicinal Chemistry, 127, 703-714. doi: 10.1016/j.ejmech.2016.10.044
2016
Journal Article
Helix nucleation by the smallest known α-helix in water
Hoang, Huy N., Driver, Russell W., Beyer, Renee L., Hill, Timothy A., de Araujo, Aline D., Plisson, Fabien, Harrison, Rosemary S., Goedecke, Lena, Shepherd, Nicholas E. and Fairlie, David P. (2016). Helix nucleation by the smallest known α-helix in water. Angewandte Chemie (International Edition), 55 (29), 8275-8279. doi: 10.1002/anie.201602079
Funding
Past funding
Supervision
Availability
- Dr Huy Hoang is:
- Available for supervision
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Supervision history
Completed supervision
-
2020
Doctor Philosophy
Synthetic and Structural Studies of Small Cyclic Peptides
Associate Advisor
Other advisors: Professor David Fairlie
-
2010
Doctor Philosophy
Structural Studies of Cyclic Peptides
Associate Advisor
Other advisors: Professor David Fairlie
Media
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