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2016 Journal Article Transcriptomic and behavioural characterisation of a mouse model of burn pain identify the cholecystokinin 2 receptor as an analgesic targetYin, Kathleen, Deuis, Jennifer R., Lewis, Richard J. and Vetter, Irina (2016). Transcriptomic and behavioural characterisation of a mouse model of burn pain identify the cholecystokinin 2 receptor as an analgesic target. Molecular Pain, 12 1744806916665366, 1-13. doi: 10.1177/1744806916665366 |
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2016 Journal Article Interaction of tarantula venom peptide ProTx-II with lipid membranes is a prerequisite for its inhibition of human voltage-gated sodium channel NaV1.7Troeira Henriques, Sonia, Deplazes, Evelyne, Lawrence, Nicole, Cheneval, Olivier, Chaousis, Stephanie, Inserra, Marco, Thongyoo, Panumart, King, Glenn F., Mark, Alan E., Vetter, Irina, Craik, David J. and Schroeder, Christina Ingrid (2016). Interaction of tarantula venom peptide ProTx-II with lipid membranes is a prerequisite for its inhibition of human voltage-gated sodium channel NaV1.7. The Journal of Biological Chemistry, 291 (33), 17049-17065. doi: 10.1074/jbc.M116.729095 |
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2016 Journal Article Rapid extraction and identification of maitotoxin and ciguatoxin-like toxins from Caribbean and Pacific Gambierdiscus using a new functional bioassayLewis, Richard J., Inserra, Marco, Vetter, Irina, Holland, William C., Hardison, D. Ransom, Tester, Patricia A. and Litaker, R. Wayne (2016). Rapid extraction and identification of maitotoxin and ciguatoxin-like toxins from Caribbean and Pacific Gambierdiscus using a new functional bioassay. PLoS ONE, 11 (7) e0160006, e0160006. doi: 10.1371/journal.pone.0160006 |
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2016 Journal Article How hot is it Down Under?Mündel, Toby, Nalivaiko, Eugene, Kent, Stephen, Maloney, Shane K. and Vetter, Irina (2016). How hot is it Down Under?. Temperature, 3 (3), 355-357. doi: 10.1080/23328940.2016.1218991 |
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2016 Journal Article Release of neuropeptides from a neuro-cutaneous co-culture model: a novel in vitro model for studying sensory effects of ciguatoxinsLe Garrec, Raphaele, L'herondelle, Killian, Le Gall-Ianotto, Christelle, Lebonvallet, Nicolas, Leschiera, Raphael, Buhe, Virginie, Talagas, Matthieu, Vetter, Irina, Lewis, Richard J. and Misery, Laurent (2016). Release of neuropeptides from a neuro-cutaneous co-culture model: a novel in vitro model for studying sensory effects of ciguatoxins. Toxicon, 116, 4-10. doi: 10.1016/j.toxicon.2015.11.004 |
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2016 Journal Article Development of a μO-conotoxin analogue with improved lipid membrane interactions and potency for the analgesic target NaV1.8Deuis, Jennifer R, Dekan, Zoltan, Inserra, Marco C., Lee, Tzong-Hsien, Aguilar, Marie-Isabel, Craik, David J., Lewis, Richard J., Alewood, Paul F., Mobli, Mehdi, Schroeder, Christina I., Henriques, Sónia Troeira and Vetter, Irina (2016). Development of a μO-conotoxin analogue with improved lipid membrane interactions and potency for the analgesic target NaV1.8. Journal of Biological Chemistry, 291 (22), 11829-11842. doi: 10.1074/jbc.M116.721662 |
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2016 Journal Article Characterization of Three Venom Peptides from the Spitting Spider Scytodes thoracicaAriki, Nathanial K., Muñoz, Lisa E., Armitage, Elizabeth L., Goodstein, Francesca R., George, Kathryn G, Smith, Vanessa L., Vetter, Irina, Herzig, Volker, King, Glenn F. and Loening, Nikolaus M. (2016). Characterization of Three Venom Peptides from the Spitting Spider Scytodes thoracica. PLoS One, 11 (5) e0156291, e0156291. doi: 10.1371/journal.pone.0156291 |
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2016 Journal Article Neuronal cell lines as model dorsal root ganglion neurons: a transcriptomic comparisonYin, Kathleen, Baillie, Gregory J. and Vetter, Irina (2016). Neuronal cell lines as model dorsal root ganglion neurons: a transcriptomic comparison. Molecular Pain, 12 1744806916646111, 1-17. doi: 10.1177/1744806916646111 |
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2016 Journal Article Analgesic effects of GpTx-1, PF-04856264 and CNV1014802 in a mouse model of NaV1.7-Mediated painDeuis, Jennifer R., Wingerd, Joshua S., Winter, Zoltan, Durek, Thomas, Dekan, Zoltan, Sousa, Silmara R., Zimmermann, Katharina, Hoffmann, Tali, Weidner, Christian, Nassar, Mohammed A., Alewood, Paul F., Lewis, Richard J. and Vetter, Irina (2016). Analgesic effects of GpTx-1, PF-04856264 and CNV1014802 in a mouse model of NaV1.7-Mediated pain. Toxins, 8 (3) 78, 78. doi: 10.3390/toxins8030078 |
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2016 Journal Article The thermal probe test: a novel behavioral assay to quantify thermal paw withdrawal thresholds in miceDeuis, Jennifer R. and Vetter, Irina (2016). The thermal probe test: a novel behavioral assay to quantify thermal paw withdrawal thresholds in mice. Temperature, 3 (2), 199-207. doi: 10.1080/23328940.2016.1157668 |
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2016 Journal Article Evaluation of known and novel inhibitors of Orai1-mediated store operated Ca2+ entry in MDA-MB-231 breast cancer cells using a Fluorescence Imaging Plate Reader assayAzimi, Iman, Flanagan, Jack U., Stevenson, Ralph J., Inserra, Marco, Vetter, Irina, Monteith, Gregory R. and Denny, William A. (2016). Evaluation of known and novel inhibitors of Orai1-mediated store operated Ca2+ entry in MDA-MB-231 breast cancer cells using a Fluorescence Imaging Plate Reader assay. Bioorganic and Medicinal Chemistry, 25 (1), 440-449. doi: 10.1016/j.bmc.2016.11.007 |
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2015 Journal Article Vps26B-retromer negatively regulates plasma membrane resensitization of PAR-2Bugarcic, Andrea, Vetter, Irina, Chalmers, Silke, Kinna, Genevieve, Collins, Brett M. and Teasdale, Rohan D. (2015). Vps26B-retromer negatively regulates plasma membrane resensitization of PAR-2. Cell Biology International, 39 (11), 1299-1306. doi: 10.1002/cbin.10508 |
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2015 Journal Article Activation of k opioid receptors in cutaneous nerve endings by conorphin-1, a novel subtype-selective conopeptide, does not mediate peripheral analgesiaDeuis, Jennifer, Whately, Ella, Brust, Andreas, Inserra, Marco, Asvadi, Naghmeh Hajarol, Lewis, Richard J., Alewood, Paul F., Cabot, Peter J. and Vetter, Irina (2015). Activation of k opioid receptors in cutaneous nerve endings by conorphin-1, a novel subtype-selective conopeptide, does not mediate peripheral analgesia. ACS Chemical Neuroscience, 6 (10), 1751-1758. doi: 10.1021/acschemneuro.5b00113 |
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2015 Journal Article Comparative Venomics Reveals the Complex Prey Capture Strategy of the Piscivorous Cone Snail Conus catusHimaya S.W.A., Jin, Ai-Hua, Dutertre, Sebastien, Giacomotto, Jean, Mohialdeen, Hoshyar, Vetter, Irina, Alewood, Paul F. and Lewis, Richard J. (2015). Comparative Venomics Reveals the Complex Prey Capture Strategy of the Piscivorous Cone Snail Conus catus. Journal of Proteome Research, 14 (10), 4372-4381. doi: 10.1021/acs.jproteome.5b00630 |
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2015 Journal Article (-)-Pentylsedinine, a new alkaloid from the leaves of lobelia tupa with agonist activity at nicotinic acetylcholine receptorPaz, Cristian, Becerra, Jose, Silva, Mario, Burgos, Viviana, Heydenreich, Matthias, Schmidt, Bernd, Thu Tran and Vetter, Irina (2015). (-)-Pentylsedinine, a new alkaloid from the leaves of lobelia tupa with agonist activity at nicotinic acetylcholine receptor. Natural Product Communications, 10 (8) 1934578X1501000810, 1355-1357. doi: 10.1177/1934578x1501000810 |
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2015 Journal Article Identification and characterization of ProTx-III [μ-TRTX-Tp1a], a new voltage-gated sodium channel inhibitor from venom of the tarantula Thrixopelma pruriensCardoso, Fernanda C., Deka, Zoltan, Rosengren, K. Johan, Erickson, Andelain, Vetter, Irina, Deuis, Jennifer R., Herzig, Volker, Alewood, Paul F., King, Glenn F. and Lewis, Richard J. (2015). Identification and characterization of ProTx-III [μ-TRTX-Tp1a], a new voltage-gated sodium channel inhibitor from venom of the tarantula Thrixopelma pruriens. Molecular Pharmacology, 88 (2), 291-303. doi: 10.1124/mol.115.098178 |
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2015 Journal Article δ-Conotoxin SuVIA suggests an evolutionary link between ancestral predator defence and the origin of fish-hunting behaviour in carnivorous cone snailsJin, Ai-Hua, Israel, Mathilde R., Inserra, Marco, Smith, Jennifer J., Lewis, Richard J., Alewood, Paul F., Vetter, Irina and Dutertre, Sebastien (2015). δ-Conotoxin SuVIA suggests an evolutionary link between ancestral predator defence and the origin of fish-hunting behaviour in carnivorous cone snails. Proceedings of the Royal Society B: Biological Sciences, 282 (1811) 20150817, 1-8. doi: 10.1098/rspb.2015.0817 |
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2015 Journal Article Seven novel modulators of the analgesic target NaV1.7 uncovered using a high-throughput venom-based discovery approachKlint, Julie K., Smith, Jennifer J., Vetter, Irina, Rupasinghe, Darshani B., Er, Sing Yan, Senff, Sebastian, Herzig, Volker, Mobli, Mehdi, Lewis, Richard J., Bosmans, Frank and King, Glenn F. (2015). Seven novel modulators of the analgesic target NaV1.7 uncovered using a high-throughput venom-based discovery approach. British Journal of Pharmacology, 172 (10), 2445-2458. doi: 10.1111/bph.13081 |
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2015 Journal Article Inhibition of N-type calcium channels by fluorophenoxyanilide derivativesGleeson, Ellen C., Graham, Janease E., Spiller, Sandro, Vetter, Irina, Lewis, Richard J., Duggan, Peter J. and Tuck, Kellie L. (2015). Inhibition of N-type calcium channels by fluorophenoxyanilide derivatives. Marine Drugs, 13 (4), 2030-2045. doi: 10.3390/md13042030 |
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2015 Journal Article α-conotoxin MrIC is a biased agonist at α7 nicotinic acetylcholine receptorsMueller, Alexander, Starobova, Hana, Inserra, Marco C., Jin, Ai-Hua, Deuis, Jennifer R., Dutertre, Sebastien, Lewis, Richard J., Alewood, Paul F., Daly, Norelle L. and Vetter, Irina (2015). α-conotoxin MrIC is a biased agonist at α7 nicotinic acetylcholine receptors. Biochemical Pharmacology, 94 (2), 155-163. doi: 10.1016/j.bcp.2015.01.011 |
