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2026 Journal Article NeuO-mediated O-acetylation of uropathogenic Escherichia coli K1 capsule enhances resistance to phage and neutrophil killingWalker, Lachlan L., Nhu, Nguyen Thi Khanh, Lian, Zheng Jie, Peters, Kate M., Monteleone, Mercedes, Connolly, James P. R., Walker, Mark J., Forde, Brian M., Schroder, Kate, Sweet, Matthew J., Phan, Minh-Duy and Schembri, Mark A. (2026). NeuO-mediated O-acetylation of uropathogenic Escherichia coli K1 capsule enhances resistance to phage and neutrophil killing. Journal of Bacteriology, 208 (3) e00610-25, 1-13. doi: 10.1128/jb.00610-25 |
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2025 Conference Publication State of Care of Patients With Autoinflammatory Disorders at the Queensland Children’s HospitalPinzon-Charry, Alberto, Tan, Joachim, Melo, Mariana, Wilcocks, Sophie, McNaughton, Peter, James, Rebecca, Peake, Jane, Schroder, Kate and Whitehead, Ben (2025). State of Care of Patients With Autoinflammatory Disorders at the Queensland Children’s Hospital. 35th Annual Conference of the Australasian Society of Clinical Immunology and Allergy (ASCIA), Brisbane, QLD Australia, 2-5 September 2025. New York, NY United States: Rockefeller University Press. doi: 10.70962/ascia2025abstract.p167 |
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2025 Journal Article NLRP1 under pressure: An overview of the NLRP1 inflammasome as a sensor of cellular stressYap, Jeremy Kean Yi, Duszyc, Kinga and Schroder, Kate (2025). NLRP1 under pressure: An overview of the NLRP1 inflammasome as a sensor of cellular stress. Molecular Cell, 85 (20), 3853-3861. doi: 10.1016/j.molcel.2025.09.018 |
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2025 Journal Article Cardiolipin inhibits the non-canonical inflammasome by preventing LPS binding to caspase-4/11Pizzuto, Malvina, Monteleone, Mercedes, Burgener, Sabrina Sofia, Began, Jakub, Kurera, Melan, Chia, Jing Rong, Frampton, Emmanuelle, Crawford, Joanna, Oliveira, Monalisa, Kenney, Kirsten M., Coombs, Jared R., Yamamoto, Masahiro, Man, Si Ming, Broz, Petr, Pelegrin, Pablo and Schroder, Kate (2025). Cardiolipin inhibits the non-canonical inflammasome by preventing LPS binding to caspase-4/11. The EMBO Journal, 44 (16), 4419-4442. doi: 10.1038/s44318-025-00507-z |
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2025 Other Outputs Paraquat licences α-Synuclein to trigger NLRP3-dependent pyroptosis in microgliaCao, Yuzhihan, Deora, Vandana, Khan, Nemat, Robertson, Avril A. B., Schroder, Kate, Cooper, Matthew A., Woodruff, Trent M. and Albornoz, Eduardo A. (2025). Paraquat licences α-Synuclein to trigger NLRP3-dependent pyroptosis in microglia. doi: 10.1101/2025.07.23.666340 |
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2025 Journal Article Spectosis: dying for a complementCoombs, Jared R., Burgener, Sabrina S. and Schroder, Kate (2025). Spectosis: dying for a complement. Immunity, 58 (6), 1372-1374. doi: 10.1016/j.immuni.2025.05.017 |
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2025 Journal Article Caspase-1 self-terminates protease activity to enforce homeostasis and prevent inflammasome-driven diseasesBurgener, Sabrina Sofia, Milner, Mark Thomas, Dey, Shoumit, Morgan, Pooranee K., Blackmore, Daniel G., Frampton, Emmanuelle, Miller, Gregory, Duarte de Oliveira, Monalisa, Kenney, Kirsten Myra, Bajracharya, Rinie, Baumgartner, Ulrich, Collins, Thomas J. C., Xiong, Zherui, Nguyen, Quan, Meikle, Peter J., Bodea, Liviu-Gabriel, Clouston, Andrew, Boucher, Dave, Götz, Jurgen, Murphy, Andrew J., Kaye, Paul M. and Schroder, Kate (2025). Caspase-1 self-terminates protease activity to enforce homeostasis and prevent inflammasome-driven diseases. BioRxiv. doi: 10.1101/2025.04.28.651119 |
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2025 Journal Article Characterization of a novel covS SNP identified in Australian group A Streptococcus isolates derived from the M1 UK lineageRichter, Johanna, Cork, Amanda J., Ong, Yvette, Keller, Nadia, Hayes, Andrew J., Schembri, Mark A., Jennison, Amy V., Davies, Mark R., Schroder, Kate, Walker, Mark J. and Brouwer, Stephan (2025). Characterization of a novel covS SNP identified in Australian group A Streptococcus isolates derived from the M1 UK lineage. mBio, 16 (2) e0336624, e0336624. doi: 10.1128/mbio.03366-24 |
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2025 Journal Article The design, synthesis, and biological evaluation of 5,6,7,8-tetrahydropteridines as anti-inflammatory compoundsChen, Rachel M., Emming, Stefan, Cinnamon, Roseanna, Cameron, Jacob P., Schroder, Kate, Kobe, Bostjan and Robertson, Avril A. B. (2025). The design, synthesis, and biological evaluation of 5,6,7,8-tetrahydropteridines as anti-inflammatory compounds. Organic & Biomolecular Chemistry, 23 (1), 174-182. doi: 10.1039/d4ob01453g |
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2025 Journal Article Inflammasome components as new therapeutic targets in inflammatory diseaseColl, Rebecca C. and Schroder, Kate (2025). Inflammasome components as new therapeutic targets in inflammatory disease. Nature Reviews Immunology, 25 (1) 978513, 22-41. doi: 10.1038/s41577-024-01075-9 |
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2025 Journal Article Towards a molecular and structural definition of cell deathArama, Eli, Cosentino, Katia, Czabotar, Peter E., Gan, Boyi, Hartland, Elizabeth, Jiang, Xuejun, Kagan, Jonathan C., Nagata, Shigekazu, Schroder, Kate, Sun, Liming, Xu, Daichao and Yuan, Junying (2025). Towards a molecular and structural definition of cell death. Nature Structural and Molecular Biology, 32 (10), 1854-1858. doi: 10.1038/s41594-025-01646-x |
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2024 Journal Article Author Correction: Inflammasome components as new therapeutic targets in inflammatory diseaseColl, Rebecca C. and Schroder, Kate (2024). Author Correction: Inflammasome components as new therapeutic targets in inflammatory disease. Nature Reviews Immunology, 25 (2), 153-153. doi: 10.1038/s41577-024-01123-4 |
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2024 Journal Article Pyroptotic cell corpses are crowned with F-actin-rich filopodia that engage CLEC9A signaling in incoming dendritic cellsHolley, Caroline L., Monteleone, Mercedes, Fisch, Daniel, Libert, Alexandre E. S., Ju, Robert J., Choi, Joon H., Condon, Nicholas D., Emming, Stefan, Crawford, Joanna, Lawrence, Grace M. E. P., Coombs, Jared R., Lefevre, James G., Bajracharya, Rinie, Lahoud, Mireille H., Yap, Alpha S., Hamilton, Nicholas, Stehbens, Samantha J., Kagan, Jonathan C., Ariotti, Nicholas, Burgener, Sabrina S. and Schroder, Kate (2024). Pyroptotic cell corpses are crowned with F-actin-rich filopodia that engage CLEC9A signaling in incoming dendritic cells. Nature Immunology, 26 (1) eaas8995, 1-35. doi: 10.1038/s41590-024-02024-3 |
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2024 Journal Article Cardiolipin Inhibits the Noncanonical Inflammasome by Preventing LPS Binding to Caspase 4/11 to Mitigate Endotoxemia in VivoPizzuto, Malvina, Monteleone, Mercedes, Burgener, Sabrina Sofia, Began, Jakub, Kurera, Melan, Chia, Jing Rong, Frampton, Emmanuelle, Crawford, Joanna, Oliveira, Monalisa, Kenney, Kirsten M., Coombs, Jared R., Yamamoto, Masahiro, Man, Si Ming, Broz, Petr, Pelegrin, Pablo and Schroder, Kate (2024). Cardiolipin Inhibits the Noncanonical Inflammasome by Preventing LPS Binding to Caspase 4/11 to Mitigate Endotoxemia in Vivo. BioRxiv, 1-24. doi: 10.1101/2024.10.14.618051 |
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2024 Journal Article Ornithine lipid is a partial TLR4 agonist and NLRP3 activatorPizzuto, Malvina, Hurtado-Navarro, Laura, Molina-Lopez, Cristina, Soubhye, Jalal, Gelbcke, Michel, Rodriguez-Lopez, Silvia, Ruysschaert, Jean-Marie, Schroder, Kate and Pelegrin, Pablo (2024). Ornithine lipid is a partial TLR4 agonist and NLRP3 activator. Cell Reports, 43 (10) 114788, 1-24. doi: 10.1016/j.celrep.2024.114788 |
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2024 Journal Article The septin modifier, forchlorfenuron, activates NLRP3 via a potassium-independent mitochondrial axisHolley, Caroline L., Emming, Stefan, Monteleone, Mercedes M., Mellacheruvu, Manasa, Kenney, Kirsten M., Lawrence, Grace M.E.P., Coombs, Jared R., Burgener, Sabrina S. and Schroder, Kate (2024). The septin modifier, forchlorfenuron, activates NLRP3 via a potassium-independent mitochondrial axis. Cell Chemical Biology, 31 (5), 962-972.e4. doi: 10.1016/j.chembiol.2024.04.012 |
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2024 Journal Article Mechanistic insights from inflammasome structuresFu, Jianing, Schroder, Kate and Wu, Hao (2024). Mechanistic insights from inflammasome structures. Nature Reviews Immunology, 24 (7), 518-535. doi: 10.1038/s41577-024-00995-w |
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2024 Journal Article Fluorochrome‐labeled inhibitors of caspase‐1 require membrane permeabilization to efficiently access caspase‐1 in macrophagesThygesen, Sara J., Burgener, Sabrina S., Mudai, Prerna, Monteleone, Mercedes, Boucher, Dave, Sagulenko, Vitaliya, Schroder, Kate and Stacey, Katryn J. (2024). Fluorochrome‐labeled inhibitors of caspase‐1 require membrane permeabilization to efficiently access caspase‐1 in macrophages. European Journal of Immunology, 54 (5) 2350515, e2350515. doi: 10.1002/eji.202350515 |
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2024 Journal Article NLRP12 interacts with NLRP3 to block the activation of the human NLRP3 inflammasomeCoombs, Jared R., Zamoshnikova, Alina, Holley, Caroline L., Maddugoda, Madhavi P., Teo, Daniel Eng Thiam, Chauvin, Camille, Poulin, Lionel F, Vitak, Nazarii, Ross, Connie M., Mellacheruvu, Manasa, Coll, Rebecca C., Heinz, Leonhard X., Burgener, Sabrina S., Emming, Stefan, Chamaillard, Mathias, Boucher, Dave and Schroder, Kate (2024). NLRP12 interacts with NLRP3 to block the activation of the human NLRP3 inflammasome. Science Signaling, 17 (820) abg8145, eabg8145. doi: 10.1126/scisignal.abg8145 |
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2024 Journal Article Publisher Correction:: Inflammasome components as new therapeutic targets in inflammatory disease (Nature Reviews Immunology, (2024), 10.1038/s41577-024-01075-9)Coll, Rebecca C. and Schroder, Kate (2024). Publisher Correction:: Inflammasome components as new therapeutic targets in inflammatory disease (Nature Reviews Immunology, (2024), 10.1038/s41577-024-01075-9). Nature Reviews Immunology, 25 (2), 153-153. doi: 10.1038/s41577-024-01122-5 |