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2019 Journal Article Variation in hemolysin A expression between uropathogenic Escherichia coli isolates determines NLRP3-dependent vs. -independent macrophage cell death and host colonizationMurthy, Ambika M. V., Sullivan, Matthew J., Nhu, Nguyen Thi Khanh, Lo, Alvin W., Phan, Minh-Duy, Peters, Kate M., Boucher, Dave, Schroder, Kate, Beatson, Scott A., Ulett, Glen C., Schembri, Mark A. and Sweet, Matthew J. (2019). Variation in hemolysin A expression between uropathogenic Escherichia coli isolates determines NLRP3-dependent vs. -independent macrophage cell death and host colonization. FASEB Journal : official publication of the Federation of American Societies for Experimental Biology, 33 (6), fj201802100R-7450. doi: 10.1096/fj.201802100R |
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2019 Journal Article The Salmonella pathogenicity island-2 subverts human NLRP3 and NLRC4 inflammasome responsesBierschenk, Damien, Monteleone, Mercedes, Moghaddas, Fiona, Baker, Paul J., Masters, Seth L., Boucher, Dave and Schroder, Kate (2019). The Salmonella pathogenicity island-2 subverts human NLRP3 and NLRC4 inflammasome responses. Journal of Leukocyte Biology, 105 (2), 401-410. doi: 10.1002/JLB.MA0318-112RR |
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2019 Journal Article Autophagy, Inflammation, and Metabolism (AIM) Center in its second yearDeretic, Vojo, Prossnitz, Eric, Burge, Mark, Campen, Matthew J., Cannon, Judy, Liu, Ke Jian, Liu, Meilian, Hall, Pamela, Sklar, Larry A., Allers, Lee, Mariscal, Luisa, Garcia, Sally Ann, Weaver, John, Baehrecke, Eric H., Behrends, Christian, Cecconi, Francesco, Codogno, Patrice, Chen, Guang-Chao, Elazar, Zvulun, Eskelinen, Eeva-Liisa, Fourie, Bernard, Gozuacik, Devrim, Hong, Wanjin, Jo, Eun-Kyeong, Johansen, Terje, Juhász, Gábor, Kimchi, Adi, Ktistakis, Nicholas, Kroemer, Guido ... Klionsky, Daniel J. (2019). Autophagy, Inflammation, and Metabolism (AIM) Center in its second year. Autophagy, 15 (10), 1-5. doi: 10.1080/15548627.2019.1634444 |
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2018 Journal Article NLRC3 restrains responses to a THolley, Caroline L., Coll, Rebecca C. and Schroder, Kate (2018). NLRC3 restrains responses to a T. Immunity, 49 (6), 989-991. doi: 10.1016/j.immuni.2018.12.003 |
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2018 Journal Article Dimerization and auto-processing induce caspase-11 protease activation within the non-canonical inflammasomeRoss, Connie, Chan, Amy H., Von Pein, Jessica, Boucher, Dave and Schroder, Kate (2018). Dimerization and auto-processing induce caspase-11 protease activation within the non-canonical inflammasome. Life Science Alliance, 1 (6) e201800237, e201800237. doi: 10.26508/lsa.201800237 |
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2018 Journal Article Correction: Mitochondrial DNA synthesis fuels NLRP3 inflammasomeColl, Rebecca C., Holley, Caroline L. and Schroder, Kate (2018). Correction: Mitochondrial DNA synthesis fuels NLRP3 inflammasome. Cell Research, 28 (12), 1202-1202. doi: 10.1038/s41422-018-0112-9 |
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2018 Journal Article Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in miceGordon, Richard, Albornoz, Eduardo A., Christie, Daniel C., Langley, Monica R., Kumar, Vinod, Mantovani, Susanna, Robertson, Avril A. B., Butler, Mark S., Rowe, Dominic B., O'Neill, Luke A., Kanthasamy, Anumantha G., Schroder, Kate, Cooper, Matthew A. and Woodruff, Trent M. (2018). Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice. Science Translational Medicine, 10 (465) aah4066, eaah4066. doi: 10.1126/scitranslmed.aah4066 |
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2018 Journal Article Mitochondrial DNA synthesis fuels NLRP3 inflammasomeColl, Rebecca C., Holley, Caroline L. and Schroder, Kate (2018). Mitochondrial DNA synthesis fuels NLRP3 inflammasome. Cell Research, 28 (11), 1046-1047. doi: 10.1038/s41422-018-0093-8 |
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2018 Journal Article Hepatic expression profiling identifies steatosis-independent and steatosis-driven advanced fibrosis genesRamnath, Divya, Irvine, Katharine M., Lukowski, Samuel W., Horsfall, Leigh U., Loh, Zhixuan, Clouston, Andrew D., Patel, Preya J., Fagan, Kevin J., Iyer, Abishek, Lampe, Guy, Stow, Jennifer L., Schroder, Kate, Fairlie, David P., Powell, Joseph E., Powell, Elizabeth E. and Sweet, Matthew J. (2018). Hepatic expression profiling identifies steatosis-independent and steatosis-driven advanced fibrosis genes. JCI Insight, 3 (14) e120274. doi: 10.1172/jci.insight.120274 |
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2018 Journal Article Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence: supporting the next generation of autophagy researchers and fostering international collaborationsDeretic, Vojo, Prossnitz, Eric, Burge, Mark, Campen, Matthew J., Cannon, Judy, Liu, Ke Jian, Sklar, Larry A., Allers, Lee, Garcia, Sally Ann, Baehrecke, Eric H., Behrends, Christian, Cecconi, Francesco, Codogno, Patrice, Chen, Guang-Chao, Elazar, Zvulun, Eskelinen, Eeva-Liisa, Fourie, Bernard, Gozuacik, Devrim, Hong, Wanjin, Hotamisligi, Gokhan, Jäättelä, Marja, Jo, Eun-Kyeong, Johansen, Terje, Juhász, Gábor, Kimchi, Adi, Ktistakis, Nicholas, Kroemer, Guido, MIzushima, Noboru, Münz, Christian ... Klionsky, Daniel J. (2018). Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence: supporting the next generation of autophagy researchers and fostering international collaborations. Autophagy, 14 (6) 15548627.2018.1465784, 925-929. doi: 10.1080/15548627.2018.1465784 |
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2018 Journal Article MCC950, a specific small molecule inhibitor of NLRP3 inflammasome attenuates colonic inflammation in spontaneous colitis micePerera, Agampodi Promoda, Fernando, Ruchira, Shinde, Tanvi, Gundamaraju, Rohit, Southam, Benjamin, Sohal, Sukhwinder Singh, Robertson, Avril A. B., Schroder, Kate, Kunde, Dale and Eri, Rajaraman (2018). MCC950, a specific small molecule inhibitor of NLRP3 inflammasome attenuates colonic inflammation in spontaneous colitis mice. Scientific Reports, 8 (1) 8618, 8618. doi: 10.1038/s41598-018-26775-w |
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2018 Journal Article Cutting edge: blockade of inhibitor of apoptosis proteins sensitizes neutrophils to TNF- but not lipopolysaccharide-mediated cell death and IL-1β secretionChen, Kaiwen W., Lawlor, Kate E., von Pein, Jessica B., Boucher, Dave, Gerlic, Motti, Croker, Ben A., Bezbradica, Jelena S., Vince, James E and Schroder, Kate (2018). Cutting edge: blockade of inhibitor of apoptosis proteins sensitizes neutrophils to TNF- but not lipopolysaccharide-mediated cell death and IL-1β secretion. Journal of Immunology, 200 (10), 3341-3346. doi: 10.4049/jimmunol.1701620 |
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2018 Journal Article IFN regulatory factor 3 balances Th1 and T follicular helper immunity during nonlethal blood-stage Plasmodium infectionJames, Kylie R., Soon, Megan S. F., Sebina, Ismail, Fernandez-Ruiz, Daniel, Davey, Gayle, Liligeto, Urijah N., Nair, Arya Sheela, Fogg, Lily G., Edwards, Chelsea L., Best, Shannon E., Lansink, Lianne I. M., Schroder, Kate, Wilson, Jane A. C., Austin, Rebecca, Suhrbier, Andreas, Lane, Steven W., Hill, Geoffrey R., Engwerda, Christian R., Heath, William R. and Haque, Ashraful (2018). IFN regulatory factor 3 balances Th1 and T follicular helper immunity during nonlethal blood-stage Plasmodium infection. Journal of Immunology, 200 (4), 1443-1456. doi: 10.4049/jimmunol.1700782 |
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2018 Journal Article Multiple inflammasomes may regulate the interleukin-1-driven inflammation in protracted bacterial bronchitisChen, Alice C. -H., Tran, Hai B., Xi, Yang, Yerkovich, Stephanie T., Baines, Katherine J., Pizzutto, Susan J., Carroll, Melanie, Robertson, Avril A. B., Cooper, Matthew A., Schroder, Kate, Simpson, Jodie L., Gibson, Peter G., Hodge, Greg, Masters, Ian B., Buntain, Helen M., Petsky, Helen L., Prime, Samantha J., Chang, Anne B., Hodge, Sandra and Upham, John W. (2018). Multiple inflammasomes may regulate the interleukin-1-driven inflammation in protracted bacterial bronchitis. ERJ Open Research, 4 (1) 00130-2017, 00130-2017. doi: 10.1183/23120541.00130-2017 |
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2018 Book Chapter Quantifying caspase-1 activity in murine macrophagesBoucher, Dave, Chan, Amy, Ross, Connie and Schroder, Kate (2018). Quantifying caspase-1 activity in murine macrophages. Inflammation and cancer. (pp. 163-176) edited by Brendan J. Jenkins. New York, NY, United States: Humana Press. doi: 10.1007/978-1-4939-7568-6_14 |
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2017 Journal Article Mechanisms and Consequences of Inflammasome ActivationSchroder, Kate, Kanneganti, Thirumala-Devi, Shao, Feng and Broz, Petr (2017). Mechanisms and Consequences of Inflammasome Activation. Journal of Molecular Biology, 430 (2), 131-132. doi: 10.1016/j.jmb.2017.12.005 |
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2017 Conference Publication XIAP deficiency results in excess NLRP3 inflammasome activation and cell death as a consequence of TLR-MyD88 induced cIAP1-TRAF2 degradationLawlor, Kate, Feltham, Rebecca, Yabal, Monica, Conos, Stephanie, Chen, Kaiwen, Nguyen, Tan, Hall, Cathrine, Chatfield, Simon, D'Silva, Damian, Pang, Kenneth, Schroder, Kate, Silke, John, Vaux, David, Jost, Philipp and Vince, James (2017). XIAP deficiency results in excess NLRP3 inflammasome activation and cell death as a consequence of TLR-MyD88 induced cIAP1-TRAF2 degradation. 5th Annual Meeting of the International-Cytokine-and-Interferon-Society (ICIS), Kanazawa Japan, Oct 29-Nov 02, 2017. LONDON: ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD. |
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2017 Journal Article Zebrafish earns its stripes for in vivo ASC speck dynamicsBezbradica, Jelena S. and Schroder, Kate (2017). Zebrafish earns its stripes for in vivo ASC speck dynamics. Journal of Cell Biology, 216 (9), 2615-2618. doi: 10.1083/jcb.201708002 |
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2017 Other Outputs Sulfonylureas and related compounds and use of the sameO'Neill, Luke , Coll, Rebecca , Cooper, Matt , Robertson, Avril , Schroder, Kate , Macleod, Angus Murray and Miller, David John (2017). Sulfonylureas and related compounds and use of the same. WO2017140778. |
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2017 Journal Article Sulfonylureas as concomitant insulin secretagogues and NLRP3 inflammasome inhibitorsHill, James R., Coll, Rebecca C., Sue, Nancy, Reid, Janet C., Dou, Jennifer, Holley, Caroline L., Pelingon, Ruby, Dickinson, Joshua B., Biden, Trevor J., Schroder, Kate, Cooper, Matthew A. and Robertson, Avril A. B. (2017). Sulfonylureas as concomitant insulin secretagogues and NLRP3 inflammasome inhibitors. ChemMedChem, 12 (17), 1449-1457. doi: 10.1002/cmdc.201700270 |
