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2016 Journal Article Salmonella-induced inflammasome activation in humansBierschenk, Damien, Boucher, Dave and Schroder, Kate (2016). Salmonella-induced inflammasome activation in humans. Molecular Immunology, 86, 38-43. doi: 10.1016/j.molimm.2016.11.009 |
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2016 Journal Article K+ efflux-independent NLRP3 inflammasome activation by small molecules targeting mitochondriaGroß, Christina J., Mishra, Ritu, Schneider, Katharina S., Médard, Guillaume, Wettmarshausen, Jennifer, Dittlein, Daniela C., Shi, Hexin, Gorka, Oliver, Koenig, Paul-Albert, Fromm, Stephan, Magnani, Giovanni, Ćiković, Tamara, Hartjes, Lara, Smollich, Joachim, Robertson, Avril A. B., Cooper, Matthew A., Schmidt-Supprian, Marc, Schuster, Michael, Schroder, Kate, Broz, Petr, Traidl-Hoffmann, Claudia, Beutler, Bruce, Kuster, Bernhard, Ruland, Jürgen, Schneider, Sabine, Perocchi, Fabiana and Groß, Olaf (2016). K+ efflux-independent NLRP3 inflammasome activation by small molecules targeting mitochondria. Immunity, 45 (4), 761-773. doi: 10.1016/j.immuni.2016.08.010 |
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2016 Other Outputs Sulfonylureas and related compounds and use of the sameO'Neill, Luke, Coll, Rebecca, Cooper, Matt, Robertson, Avril and Schroder, Kate (2016). Sulfonylureas and related compounds and use of the same. WO2016131098. |
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2016 Journal Article IL-1 contributes to the anti-cancer efficacy of ingenol mebutateLe, Thuy T., Skak, Kresten, Schroder, Kate, Schroder, Wayne A., Boyle, Glen M., Pierce, Carly J. and Suhrbier, Andreas (2016). IL-1 contributes to the anti-cancer efficacy of ingenol mebutate. PLoS One, 11 (4) e0153975, e0153975. doi: 10.1371/journal.pone.0153975 |
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2016 Journal Article Questions and Controversies in innate immune research: What is the physiological role of NLRP3?Coll, R. C., O'Neill, L. A. J. and Schroder, K. (2016). Questions and Controversies in innate immune research: What is the physiological role of NLRP3?. Cell Death Discovery, 2 (Art No.: 16019) 16019, 16019. doi: 10.1038/cddiscovery.2016.19 |
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2016 Journal Article The murine neutrophil NLRP3 inflammasome is activated by soluble but not particulate or crystalline agonistsChen, Kaiwen W., Bezbradica, Jelena S., Gross, Christina J., Wall, Adam A., Sweet, Matthew J., Stow, Jennifer L. and Schroder, Kate (2016). The murine neutrophil NLRP3 inflammasome is activated by soluble but not particulate or crystalline agonists. European Journal of Immunology, 46 (4), 1004-1010. doi: 10.1002/eji.201545943 |
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2016 Journal Article Familial auto inflammation with neutrophilic dermatosis reveals a novel regulatory mechanism of pyrin activationMasters, Seth L., Lagou, Vasiliki, Jéru, Isabelle, Baker, Paul J., Van Eyck, Lien, Parry, David A., Lawless, Dylan, De Nardo, Dominic, Garcia-Perez, Josselyn E., Dagley, Laura F., Holley, Caroline L., Dooley, James, Moghaddas, Fiona, Pasciuto, Emanuela, Jeandel, Pierre-Yves, Sciot, Raf, Lyras, Dena, Webb, Andrew I., Nicholson, Sandra E., De Somer, Lien, van Nieuwenhove, Erika, Ruuth-Praz, Julia, Copin, Bruno, Cochet, Emmanuelle, Medlej-Hashim, Myrna, Megarbane, Andre, Schroder, Kate, Savic, Sinisa, Goris, An ... Liston, Adrian (2016). Familial auto inflammation with neutrophilic dermatosis reveals a novel regulatory mechanism of pyrin activation. Science Translational Medicine, 8 (332) 332ra45, 1-9. doi: 10.1126/scitranslmed.aaf1471 |
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2016 Journal Article Sterile signals generate weaker and delayed macrophage NLRP3 inflammasome responses relative to microbial signalsBezbradica, Jelena S., Coll, Rebecca C. and Schroder, Kate (2016). Sterile signals generate weaker and delayed macrophage NLRP3 inflammasome responses relative to microbial signals. Cellular and Molecular Immunology, 1-9. doi: 10.1038/cmi.2016.11 |
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2016 Journal Article Salmonella employs multiple mechanisms to subvert the TLR-inducible zinc-mediated antimicrobial response of human macrophagesKapetanovic, Ronan, Bokil, Nilesh J., Achard, Maud E. S., Ong, Cheryl-lynn Y, Peters, Kate M., Stocks, Claudia J., Phan, Minh-Duy, Monteleone, Mercedes, Schroder, Kate, Irvine, Katharine M., Saunders, Bernadette M., Walker, Mark J., Stacey, Katryn J., McEwan, Alastair G., Schembri, Mark A. and Sweet, Matthew J. (2016). Salmonella employs multiple mechanisms to subvert the TLR-inducible zinc-mediated antimicrobial response of human macrophages. The FASEB Journal, 30 (5), 1901-1912. doi: 10.1096/fj.201500061 |
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2016 Journal Article The E3 ubiquitin ligase RNF144B is LPS-inducible in human but not mouse macrophages, and promotes inducible IL-1β expressionAriffin, Juliana K., Kapetanovic, Ronan, Schaale, Kolja, Gatica-Andrades, Marcela, Blumenthal, Antje, Schroder, Kate and Sweet, Matthew J. (2016). The E3 ubiquitin ligase RNF144B is LPS-inducible in human but not mouse macrophages, and promotes inducible IL-1β expression. Journal of Leukocyte Biology, 100 (1), 155-161. doi: 10.1189/jlb.2AB0815-339R |
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2016 Journal Article NLRP12 is a neutrophil-specific, negative regulator of in vitro cell migration but does not modulate LPS- or infection-induced NF-κB or ERK signallingZamoshnikova, Alina, Grob, Christina J., Schuster, Steffen, Chen, Kaiwen W., Wilson, Anne, Tacchini-Cottier, Fabienne and Schroder, Kate (2016). NLRP12 is a neutrophil-specific, negative regulator of in vitro cell migration but does not modulate LPS- or infection-induced NF-κB or ERK signalling. Immunobiology, 221 (2), 341-346. doi: 10.1016/j.imbio.2015.10.001 |
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2016 Book Chapter Assessment of inflammasome formation by flow cytometrySester, David P., Zamoshnikova, Alina, Thygesen, Sara J., Vajjhala, Parimala R., Cridland, Simon O., Schroder, Kate and Stacey, Katryn J. (2016). Assessment of inflammasome formation by flow cytometry. Current protocols in immunology. (pp. 14.40.1-14.40.29) edited by Coligan, John E., Bierer, Barbara, Margulies, David H., Shevach, Ethan M. and Strober, Warren. Hoboken, NJ United States: John Wiley & Sons. doi: 10.1002/cpim.13 |
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2016 Journal Article Strain- and host species-specific inflammasome activation, IL-1β release, and cell death in macrophages infected with uropathogenic Escherichia coli.Schaale, K., Peters, K. M., Murthy, A. M., Fritzsche, A. K., Phan, M.-D., Totsika, M., Robertson, A. A. B., Nichols, K. B., Cooper, M. A., Stacey, K. J., Ulett, G. C., Schroder, K., Schembri, M. A. and Sweet, M. J. (2016). Strain- and host species-specific inflammasome activation, IL-1β release, and cell death in macrophages infected with uropathogenic Escherichia coli.. Mucosal Immunology, 9 (1), 124-136. doi: 10.1038/mi.2015.44 |
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2016 Conference Publication Molecular arrangement and activation of procaspases-1 and-8 at inflammasomesVajjhala, P., Lu, A., Brown, D., Sagulenko, V, Schroder, K., Stow, J., Wu, H. and Stacey, K. (2016). Molecular arrangement and activation of procaspases-1 and-8 at inflammasomes. ICI 2016 International Congress of Immunology, Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. |
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2015 Journal Article The inflammasome adaptor ASC induces procaspase-8 death effector domain filamentsVajjhala, Parimala R., Lu, Alvin, Brown, Darren L., Pang, Siew Wai, Sagulenko, Vitaliya, Sester, David P., Cridland, Simon O., Hill, Justine M., Schroder, Kate, Stow, Jennifer L., Wu, Hao and Stacey, Katryn J. (2015). The inflammasome adaptor ASC induces procaspase-8 death effector domain filaments. Journal of Biological Chemistry, 290 (49), 29217-29230. doi: 10.1074/jbc.M115.687731 |
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2015 Journal Article TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunityKimura, Tomonori, Jain, Ashish, Choi, Seong Won, Mandell, Michael A., Schroder, Kate, Johansen, Terje and Deretic, Vojo (2015). TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunity. Journal of Cell Biology, 210 (6), 973-989. doi: 10.1083/jcb.201503023 |
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2015 Journal Article Mechanisms of unconventional secretion of IL-1 family cytokinesMonteleone, Mercedes, Stow, Jennifer L. and Schroder, Kate (2015). Mechanisms of unconventional secretion of IL-1 family cytokines. Cytokine, 74 (2), 213-218. doi: 10.1016/j.cyto.2015.03.022 |
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2015 Journal Article Metabolic gene expression changes in astrocytes in Multiple Sclerosis cerebral cortex are indicative of immune-mediated signalingZeis, T., Allaman, I., Gentner, M., Schroder, K., Tschopp, J., Magistretti, P. J. and Schaeren-Wiemers, N. (2015). Metabolic gene expression changes in astrocytes in Multiple Sclerosis cerebral cortex are indicative of immune-mediated signaling. Brain, Behavior, and Immunity, 48, 313-325. doi: 10.1016/j.bbi.2015.04.013 |
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2015 Journal Article Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice.Sester, David P., Sagulenko, Vitaliya, Thygesen, Sara J., Cridland, Jasmyn A., Loi, Yen Siew, Cridland, Simon O., Masters, Seth L., Genske, Ulrich, Hornung, Veit, Andoniou, Christopher E., Sweet, Matthew J., Degli-Esposti, Mariapia A., Schroder, Kate and Stacey, Katryn J. (2015). Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice.. Journal of Immunology, 195 (3), 1233-1241. doi: 10.4049/jimmunol.1402859 |
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2015 Conference Publication The adaptor protein ASC controls transplantation outcomes independently of the inflammasomeCheong, Melody, Gartlan, Kate, Tey, Siok-Keen, Kuns, Rachel, Lor, Mary, Lineburg, Katie, Tea, Bianca, Shi, Wei, Raju, Jyothy, Zhang, Ping, Varelias, Antiopi, Leveque-El Mouttie, Lucie, Olver, Stuart, Bunting, Mark, Lane, Steven, Boyle, Glen, Ting, Jenny, Schroder, Kate, Engwerda, Christian, Khanna, Kum Kum, Smyth, Mark, MacDonald, Kelli, Koyama, Motoko and Hill, Geoffrey (2015). The adaptor protein ASC controls transplantation outcomes independently of the inflammasome. Annual Meeting of the American-Association-of-Immunologists (IMMUNOLOGY), New Orleans La, May 08-12, 2015. BETHESDA: AMER ASSOC IMMUNOLOGISTS. |
