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2014 Conference Publication MCC950 is a potent and specific inhibitor of the NLRP3 inflammasome and a novel potential therapeutic for NLRP3 driven diseasesColl, Rebecca C., Robertson, Avril A. B., Chae, Jae Jin, Higgins, Sarah C., Dungan, Lara S., Munoz-Planillo, Raul, Monks, Brian G., Croker, Daniel E., Sutton, Caroline E., Stutz, Andrea, Nunez, Gabriel, Latz, Eicke, Kastner, Daniel L., Mills, Kingston H. G., Masters, Seth L., Schroder, Kate, Cooper, Matt A. and O'Neill, Luke A. J. (2014). MCC950 is a potent and specific inhibitor of the NLRP3 inflammasome and a novel potential therapeutic for NLRP3 driven diseases. 2nd Annual Meeting of the International-Cytokine-and-Interferon-Society (ICIS), Melbourne Australia, Oct 26-29, 2014. London United Kingdom: Academic Press. doi: 10.1016/j.cyto.2014.07.037 |
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2014 Conference Publication A novel approach to investigate the assembly of the NOD-like receptor inflammasomesGiles, Nichole, Sierecki, Emma, Polinkovsky, Mark, Schroder, Kate, Alexandrov, Kirill and Gambin, Yann (2014). A novel approach to investigate the assembly of the NOD-like receptor inflammasomes. Experimental Biology Meeting, San Diego Ca, 26-30 April 2014. Bethesda, MD United States: Federation of American Societies for Experimental Biology. |
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2014 Conference Publication Exploring NLRP12-An emerging member of NOD-like receptor familyZamoshnikova, Alina, Gross, Christina J., Vasquez, Flor, Schuster, Steffen, Tacchini-Cottier, Fabienne, Richards, Ayanthi and Schroder, Kate (2014). Exploring NLRP12-An emerging member of NOD-like receptor family. 2nd Annual Meeting of the International-Cytokine-and-Interferon-Society (ICIS), Melbourne Australia, 26-29 October 2014. London, United Kingdom: Academic Press. doi: 10.1016/j.cyto.2014.07.217 |
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2013 Journal Article AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASCSagulenko, V., Thygesen, S. J., Sester, D. P., Idris, A., Cridland, J. A., Vajjhala, P. R., Roberts, T., Schroder, K., Vince, J. E., Hill, J. M., Silke, J. and Stacey, K. J. (2013). AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC. Cell Death and Differentiation, 20 (9), 1149-1160. doi: 10.1038/cdd.2013.37 |
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2013 Journal Article Pattern recognition receptor function in neutrophilsThomas, Christina J. and Schroder, Kate (2013). Pattern recognition receptor function in neutrophils. Trends in Immunology, 34 (7), 317-328. doi: 10.1016/j.it.2013.02.008 |
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2013 Journal Article An antioxidant role for catecholate siderophores in SalmonellaAchard, Maud E. S, Chen, Kaiwen W., Sweet, Matthew J., Watts, Rebecca E., Schroder, Kate, Schembri, Mark A. and McEwan, Alastair G. (2013). An antioxidant role for catecholate siderophores in Salmonella. Biochemical Journal, 454 (3), 543-549. doi: 10.1042/BJ20121771 |
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2013 Journal Article Histone deacetylase 7 promotes Toll-like Receptor 4-dependent pro-inflammatory gene expression in macrophagesShakespear, Melanie R., Hohenhaus, Daniel M., Kelly, Greg M., Kamal, Nabilah A., Gupta, Praveer, Labzin, Larisa I., Schroder, Kate, Garceau, Valerie, Barbero, Sheila, Iyer, Abishek, Hume, David A., Reid, Robert C., Irvine, Katharine M., Fairlie, David P. and Sweet, Matthew J. (2013). Histone deacetylase 7 promotes Toll-like Receptor 4-dependent pro-inflammatory gene expression in macrophages. Journal of Biological Chemistry, 288 (35), 25362-25374. doi: 10.1074/jbc.M113.496281 |
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2013 Journal Article Antimicrobial functions of inflammasomesChen, Kaiwen W. and Schroder, Kate (2013). Antimicrobial functions of inflammasomes. Current Opinion in Microbiology, 16 (3), 311-318. doi: 10.1016/j.mib.2013.02.004 |
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2013 Journal Article Innate immunity, the constant gardener of antimicrobial defenseSchroder, Kate and Deretic, Vojo (2013). Innate immunity, the constant gardener of antimicrobial defense. Current Opinion in Microbiology, 16 (3), 293-295. doi: 10.1016/j.mib.2013.06.007 |
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2013 Journal Article The structure of the caspase recruitment domain of BinCARD reveals that all three cysteines can be oxidizedChen, Kai-En, Richards, Ayanthi A., Caradoc-Davies, Tom T., Vajjhala, Parimala R., Robin, Gautier, Lua, Linda H. L., Hill, Justine M., Schroder, Kate, Sweet, Matthew J., Kellie, Stuart, Kobe, Bostjan and Martin, Jennifer (2013). The structure of the caspase recruitment domain of BinCARD reveals that all three cysteines can be oxidized. Acta Crystallographica Section D: Biological Crystallography, 69 (5), 774-784. doi: 10.1107/S0907444913001558 |
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2012 Journal Article Acute lipopolysaccharide priming boosts inflammasome activation independently of inflammasome sensor inductionSchroder, Kate, Sagulenko, Vitaliya, Zamoshnikova, Alina, Richards, Ayanthi A., Cridland, Jasmyn A., Irvine, Katharine M., Stacey, Katryn J. and Sweet, Matthew J. (2012). Acute lipopolysaccharide priming boosts inflammasome activation independently of inflammasome sensor induction. Immunobiology, 217 (12), 1325-1329. doi: 10.1016/j.imbio.2012.07.020 |
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2012 Journal Article Liver repercussions of defective gut surveillanceIrvine, Katharine M., Schroder, Elizabeth E. and Powell, Elizabeth E. (2012). Liver repercussions of defective gut surveillance. Hepatology, 56 (3), 1174-1177. doi: 10.1002/hep.25944 |
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2012 Journal Article The mammalian PYHIN gene family: Phylogeny, evolution and expressionCridland, Jasmyn A., Curley, Eva Z., Wykes, Michelle N ., Schroder, Kate, Sweet, Matthew J., Roberts, Tara L., Ragan, Mark A., Kassahn, Karin S. and Stacey, Katryn J. (2012). The mammalian PYHIN gene family: Phylogeny, evolution and expression. BMC Evolutionary Biology, 12 (1) 140, 140.1-140.33. doi: 10.1186/1471-2148-12-140 |
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2012 Journal Article Novel insights into the innate immune response to non-tuberculous MycobacteriaHeinz, Leonhard X. and Schroder, Kate (2012). Novel insights into the innate immune response to non-tuberculous Mycobacteria. Immunology and Cell Biology, 90 (6), 568-570. doi: 10.1038/icb.2011.86 |
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2012 Journal Article NLRC5 deficiency selectively impairs MHC class idependent lymphocyte killing by cytotoxic T cellsStaehli, Francesco, Ludigs, Kristina, Heinz, Leonhard X., Seguin-Estevez, Queralt, Ferrero, Isabel, Braun, Marion, Schroder, Kate, Rebsamen, Manuele, Tardivel, Aubry, Mattmann, Chantal, MacDonald, H. Robson, Romero, Pedro, Reith, Walter, Guarda, Greta and Tschopp, Jurg (2012). NLRC5 deficiency selectively impairs MHC class idependent lymphocyte killing by cytotoxic T cells. Journal of Immunology, 188 (8), 3820-3828. doi: 10.4049/jimmunol.1102671 |
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2012 Journal Article The death domain-containing protein Unc5CL is a novel MyD88-independent activator of the pro-inflammatory IRAK signaling cascadeHeinz, L. X., Rebsamen, M., Rossi, D. C., Staehli, F., Schroder, K., Quadroni, M., Gross, O., Schneider, P. and Tschopp, J. (2012). The death domain-containing protein Unc5CL is a novel MyD88-independent activator of the pro-inflammatory IRAK signaling cascade. Cell Death and Differentiation, 19 (4), 722-731. doi: 10.1038/cdd.2011.147 |
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2012 Conference Publication NLRC5 deficiency impairs MHC class I-dependent lymphocyte killing by cytotoxic T cellsGuarda, G., Staehli, F., Ludigs, K., Heinz, L., Seguin-Estevez, Q., Ferrero, I., Braun, M., Schroder, K., Rebsamen, M., Tardivel, A., Mattmann, C., MacDonald, H. R., Romero, P., Reith, W. and Tschopp, J. (2012). NLRC5 deficiency impairs MHC class I-dependent lymphocyte killing by cytotoxic T cells. European Congress of Immunology, Glasgow Scotland, 5-8 September 2012. West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/imm.12001 |
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2012 Conference Publication Functional significance of evolutionary divergence in Toll-like receptor-regulated gene expression in human versus mouseSweet, M. J., Schroder, K., Irvine, K. M., Taylor, M., Bokil, N. J., Broomfield, S., Schembri, M. A., Stacey, K. J. and Hume, D. A. (2012). Functional significance of evolutionary divergence in Toll-like receptor-regulated gene expression in human versus mouse. European Congress of Immunology, Glasgow, Scotland, 5-8 September 2012. Oxford, United Kingdom: Wiley-Blackwell. doi: 10.1111/imm.12002 |
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2011 Journal Article Macrophage activation and differentiation signals regulate Schlafen-4 gene expression: Evidence for Schlafen-4 as a modulator of myelopoiesisVan Zuylen, Wendy J., Garceau, Valerie, Idris, Adi, Schroder, Kate, Irvine, Katharine M., Lattin, Jane E., Ovchinnikov, Dmitry A., Perkins, Andrew C., Cook, Andrew D., Hamilton, John A., Hertzog, Paul J., Stacey, Katryn J., Kellie, Stuart, Hume, David A. and Sweet, Matthew J. (2011). Macrophage activation and differentiation signals regulate Schlafen-4 gene expression: Evidence for Schlafen-4 as a modulator of myelopoiesis. PLoS One, 6 (1) e15723, e15723-1-e15723-13. doi: 10.1371/journal.pone.0015723 |
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2011 Journal Article Update of the FANTOM web resource: From mammalian transcriptional landscape to its dynamic regulationKawaji, H, Severin, J, Lizio, M, Forrest, ARR, van Nimwegen, E, Rehli, M, Schroder, K, Irvine, K, Suzuki, H, Carninci, P, Hayashizaki, Y and Daub, CO (2011). Update of the FANTOM web resource: From mammalian transcriptional landscape to its dynamic regulation. Nucleic Acids Research, 39 (Supp. 1), D856-D860. doi: 10.1093/nar/gkq1112 |
