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2015 Journal Article Metabolic gene expression changes in astrocytes in Multiple Sclerosis cerebral cortex are indicative of immune-mediated signalingZeis, T., Allaman, I., Gentner, M., Schroder, K., Tschopp, J., Magistretti, P. J. and Schaeren-Wiemers, N. (2015). Metabolic gene expression changes in astrocytes in Multiple Sclerosis cerebral cortex are indicative of immune-mediated signaling. Brain, Behavior, and Immunity, 48, 313-325. doi: 10.1016/j.bbi.2015.04.013 |
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2015 Journal Article Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice.Sester, David P., Sagulenko, Vitaliya, Thygesen, Sara J., Cridland, Jasmyn A., Loi, Yen Siew, Cridland, Simon O., Masters, Seth L., Genske, Ulrich, Hornung, Veit, Andoniou, Christopher E., Sweet, Matthew J., Degli-Esposti, Mariapia A., Schroder, Kate and Stacey, Katryn J. (2015). Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice.. Journal of Immunology, 195 (3), 1233-1241. doi: 10.4049/jimmunol.1402859 |
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2015 Conference Publication The adaptor protein ASC controls transplantation outcomes independently of the inflammasomeCheong, Melody, Gartlan, Kate, Tey, Siok-Keen, Kuns, Rachel, Lor, Mary, Lineburg, Katie, Tea, Bianca, Shi, Wei, Raju, Jyothy, Zhang, Ping, Varelias, Antiopi, Leveque-El Mouttie, Lucie, Olver, Stuart, Bunting, Mark, Lane, Steven, Boyle, Glen, Ting, Jenny, Schroder, Kate, Engwerda, Christian, Khanna, Kum Kum, Smyth, Mark, MacDonald, Kelli, Koyama, Motoko and Hill, Geoffrey (2015). The adaptor protein ASC controls transplantation outcomes independently of the inflammasome. Annual Meeting of the American-Association-of-Immunologists (IMMUNOLOGY), New Orleans La, May 08-12, 2015. BETHESDA: AMER ASSOC IMMUNOLOGISTS. |
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2015 Journal Article A novel flow cytometric method to assess inflammasome formationSester, David P., Thygesen, Sara J., Sagulenko, Vitaliya, Vajjhala, Parimala R., Cridland, Jasmyn A., Vitak, Nazarii, Chen, Kaiwen W., Osborne, Geoffrey W., Schroder, Kate and Katryn J. Stacey (2015). A novel flow cytometric method to assess inflammasome formation. The Journal of Immunology, 194 (1), 455-462. doi: 10.4049/jimmunol.1401110 |
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2015 Journal Article Burn the house, save the day: pyroptosis in pathogen restrictionBoucher, Dave, Chen, Kaiwen W. and Schroder, Kate (2015). Burn the house, save the day: pyroptosis in pathogen restriction. Inflammasome, 2 (1), 1-6. doi: 10.1515/infl-2015-0001 |
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2014 Journal Article Sphingomyelin phosphodiesterase Acid-like 3A (SMPDL3A) is a novel nucleotide phosphodiesterase regulated by cholesterol in human macrophagesTraini, Mathew, Quinn, Carmel M., Sandoval, Cecilia, Johansson, Erik, Schroder, Kate, Kockx, Maaike, Meikle, Peter J., Jessup, Wendy and Kritharides, Leonard (2014). Sphingomyelin phosphodiesterase Acid-like 3A (SMPDL3A) is a novel nucleotide phosphodiesterase regulated by cholesterol in human macrophages. Journal of Biological Chemistry, 289 (47), 32895-32913. doi: 10.1074/jbc.M114.612341 |
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2014 Journal Article TRAF6 is a nexus for TLR-STAT1 crosstalkBezbradica, Jelena S. and Schroder, Kate (2014). TRAF6 is a nexus for TLR-STAT1 crosstalk. Immunology and Cell Biology, 92 (9), 737-738. doi: 10.1038/icb.2014.71 |
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2014 Journal Article Rab8a interacts directly with PI3Kγ to modulate TLR4-driven PI3K and mTOR signallingLuo, Lin, Wall, Adam A., Yeo, Jeremy C., Condon, Nicholas D., Norwood, Suzanne J., Schoenwaelder, Simone, Chen, Kaiwen W., Jackson, Shaun, Jenkins, Brendan J., Hartland, Elizabeth L., Schroder, Kate, Collins, Brett M., Sweet, Matthew J. and Stow, Jennifer L. (2014). Rab8a interacts directly with PI3Kγ to modulate TLR4-driven PI3K and mTOR signalling. Nature Communications, 5 (1) 4407, 4407.1-4407.13. doi: 10.1038/ncomms5407 |
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2014 Book Chapter Inflammasomes and inflammationChen, Kaiwen W., Richards, Ayanthi A., Zamoshnikova, Alina and Schroder, Kate (2014). Inflammasomes and inflammation. Cancer and Inflammation Mechanisms: Chemical, Biological, and Clinical Aspects. (pp. 103-117) edited by Yusuke Hiraku, Shosuke Kawanishi and Hiroshi Ohshima. Hoboken, NJ, USA: John Wiley & Sons. doi: 10.1002/9781118826621.ch8 |
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2014 Conference Publication MCC950 is a potent and specific inhibitor of the NLRP3 inflammasome and a novel potential therapeutic for NLRP3 driven diseasesColl, Rebecca C., Robertson, Avril A. B., Chae, Jae Jin, Higgins, Sarah C., Dungan, Lara S., Munoz-Planillo, Raul, Monks, Brian G., Croker, Daniel E., Sutton, Caroline E., Stutz, Andrea, Nunez, Gabriel, Latz, Eicke, Kastner, Daniel L., Mills, Kingston H. G., Masters, Seth L., Schroder, Kate, Cooper, Matt A. and O'Neill, Luke A. J. (2014). MCC950 is a potent and specific inhibitor of the NLRP3 inflammasome and a novel potential therapeutic for NLRP3 driven diseases. 2nd Annual Meeting of the International-Cytokine-and-Interferon-Society (ICIS), Melbourne Australia, Oct 26-29, 2014. London United Kingdom: Academic Press. doi: 10.1016/j.cyto.2014.07.037 |
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2014 Conference Publication A novel approach to investigate the assembly of the NOD-like receptor inflammasomesGiles, Nichole, Sierecki, Emma, Polinkovsky, Mark, Schroder, Kate, Alexandrov, Kirill and Gambin, Yann (2014). A novel approach to investigate the assembly of the NOD-like receptor inflammasomes. Experimental Biology Meeting, San Diego Ca, 26-30 April 2014. Bethesda, MD United States: Federation of American Societies for Experimental Biology. |
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2014 Conference Publication Exploring NLRP12-An emerging member of NOD-like receptor familyZamoshnikova, Alina, Gross, Christina J., Vasquez, Flor, Schuster, Steffen, Tacchini-Cottier, Fabienne, Richards, Ayanthi and Schroder, Kate (2014). Exploring NLRP12-An emerging member of NOD-like receptor family. 2nd Annual Meeting of the International-Cytokine-and-Interferon-Society (ICIS), Melbourne Australia, 26-29 October 2014. London, United Kingdom: Academic Press. doi: 10.1016/j.cyto.2014.07.217 |
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2013 Journal Article AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASCSagulenko, V., Thygesen, S. J., Sester, D. P., Idris, A., Cridland, J. A., Vajjhala, P. R., Roberts, T., Schroder, K., Vince, J. E., Hill, J. M., Silke, J. and Stacey, K. J. (2013). AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC. Cell Death and Differentiation, 20 (9), 1149-1160. doi: 10.1038/cdd.2013.37 |
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2013 Journal Article Pattern recognition receptor function in neutrophilsThomas, Christina J. and Schroder, Kate (2013). Pattern recognition receptor function in neutrophils. Trends in Immunology, 34 (7), 317-328. doi: 10.1016/j.it.2013.02.008 |
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2013 Journal Article An antioxidant role for catecholate siderophores in SalmonellaAchard, Maud E. S, Chen, Kaiwen W., Sweet, Matthew J., Watts, Rebecca E., Schroder, Kate, Schembri, Mark A. and McEwan, Alastair G. (2013). An antioxidant role for catecholate siderophores in Salmonella. Biochemical Journal, 454 (3), 543-549. doi: 10.1042/BJ20121771 |
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2013 Journal Article Histone deacetylase 7 promotes Toll-like Receptor 4-dependent pro-inflammatory gene expression in macrophagesShakespear, Melanie R., Hohenhaus, Daniel M., Kelly, Greg M., Kamal, Nabilah A., Gupta, Praveer, Labzin, Larisa I., Schroder, Kate, Garceau, Valerie, Barbero, Sheila, Iyer, Abishek, Hume, David A., Reid, Robert C., Irvine, Katharine M., Fairlie, David P. and Sweet, Matthew J. (2013). Histone deacetylase 7 promotes Toll-like Receptor 4-dependent pro-inflammatory gene expression in macrophages. Journal of Biological Chemistry, 288 (35), 25362-25374. doi: 10.1074/jbc.M113.496281 |
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2013 Journal Article Antimicrobial functions of inflammasomesChen, Kaiwen W. and Schroder, Kate (2013). Antimicrobial functions of inflammasomes. Current Opinion in Microbiology, 16 (3), 311-318. doi: 10.1016/j.mib.2013.02.004 |
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2013 Journal Article Innate immunity, the constant gardener of antimicrobial defenseSchroder, Kate and Deretic, Vojo (2013). Innate immunity, the constant gardener of antimicrobial defense. Current Opinion in Microbiology, 16 (3), 293-295. doi: 10.1016/j.mib.2013.06.007 |
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2013 Journal Article The structure of the caspase recruitment domain of BinCARD reveals that all three cysteines can be oxidizedChen, Kai-En, Richards, Ayanthi A., Caradoc-Davies, Tom T., Vajjhala, Parimala R., Robin, Gautier, Lua, Linda H. L., Hill, Justine M., Schroder, Kate, Sweet, Matthew J., Kellie, Stuart, Kobe, Bostjan and Martin, Jennifer (2013). The structure of the caspase recruitment domain of BinCARD reveals that all three cysteines can be oxidized. Acta Crystallographica Section D: Biological Crystallography, 69 (5), 774-784. doi: 10.1107/S0907444913001558 |
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2012 Journal Article Acute lipopolysaccharide priming boosts inflammasome activation independently of inflammasome sensor inductionSchroder, Kate, Sagulenko, Vitaliya, Zamoshnikova, Alina, Richards, Ayanthi A., Cridland, Jasmyn A., Irvine, Katharine M., Stacey, Katryn J. and Sweet, Matthew J. (2012). Acute lipopolysaccharide priming boosts inflammasome activation independently of inflammasome sensor induction. Immunobiology, 217 (12), 1325-1329. doi: 10.1016/j.imbio.2012.07.020 |