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1998 Journal Article No evidence for the H133Y mutation in SONIC HEDGEHOG in a collection of common tumour typesWicking, C, Evans, T, Henk, B, Hayward, N, Simms, LA, Chenevix-Trench, G, Pietsch, T and Wainwright, B (1998). No evidence for the H133Y mutation in SONIC HEDGEHOG in a collection of common tumour types. Oncogene, 16 (8), 1091-1093. doi: 10.1038/sj.onc.1201644 |
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1998 Journal Article Effect of IBMX and alkaline phosphatase inhibitors on Cl- secretion in G551D cystic fibrosis mutant miceSmith, Stephen N., Delaney, Stephen J., Dorin, Julia R., Farley, Raymond, Geddes, Duncan M., Porteous, David J., Wainwright, Brandon J. and Alton, Eric W. F. W. (1998). Effect of IBMX and alkaline phosphatase inhibitors on Cl- secretion in G551D cystic fibrosis mutant mice. American Journal of Physiology - Cell Physiology, 274 (2 43-2), C492-C499. doi: 10.1152/ajpcell.1998.274.2.c492 |
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1998 Conference Publication Novel susceptibility gene for NIDDM is localised to human chromosome 12qShaw, JTE, Lovelock, PK, Duffy, D, Cardinal, J, Berkholz, JR, Kesting, JB and Wainwright, B (1998). Novel susceptibility gene for NIDDM is localised to human chromosome 12q. NEW YORK: SPRINGER VERLAG. |
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1997 Journal Article Mapping the multiple self-healing squamous epithelioma (MSSE) gene and investigation of xeroderma pigmentosum group A (XPA) and PATCHED (PTCH) as candidate genesRichards, Frances M., Goudie, David R., Cooper, Wendy N., Jene, Quitz, Barroso, Inês , Wicking, Carol, Wainwright, Brandon J. and Ferguson-Smith, Malcolm A. (1997). Mapping the multiple self-healing squamous epithelioma (MSSE) gene and investigation of xeroderma pigmentosum group A (XPA) and PATCHED (PTCH) as candidate genes. Human Genetics, 101 (3), 317-322. doi: 10.1007/s004390050635 |
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1997 Journal Article Characterisation of human patched germ line mutations in naevoid basal cell carcinoma syndromeLench, NJ, Telford, EAR, High, AS, Markham, AF, Wicking, C and Wainwright, BJ (1997). Characterisation of human patched germ line mutations in naevoid basal cell carcinoma syndrome. Human Genetics, 100 (5-6), 497-502. doi: 10.1007/s004390050541 |
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1997 Journal Article Medulloblastomas of the desmoplastic variant carry mutations of the human homologue of Drosophila patchedPietsch, T, Waha, A, Koch, A, Kraus, J, Albrecht, S, Tonn, J, Sorensen, N, Berthold, F, Henk, B, Schmandt, N, Wolf, HK, vonDeimling, A, Wainwright, B, ChenevixTrench, G, Wiestler, OD and Wicking, C (1997). Medulloblastomas of the desmoplastic variant carry mutations of the human homologue of Drosophila patched. Cancer Research, 57 (11), 2085-2088. |
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1997 Journal Article Rare mutations and no hypermethylation at the CDKN2A locus in epithelial ovarian tumoursShih, Yang-Chia, Kerr, Judith, Liu, Jim, Hurst, Terry, Khoo, Soo-Keat, Ward, Bruce, Wainwright, Brandon and Chenevix-Trench, Georgia (1997). Rare mutations and no hypermethylation at the CDKN2A locus in epithelial ovarian tumours. International Journal of Cancer, 70 (5), 508-511. doi: 10.1002/(SICI)1097-0215(19970304)70:53.0.CO;2-1 |
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1997 Journal Article Two N-terminal self-association domains are required for the dominant negative transcriptional activity of WT1 Denys-Drash mutant proteinsHolmes, G, Boterashvili, S, English, M, Wainwright, B, Licht, J and Little, M (1997). Two N-terminal self-association domains are required for the dominant negative transcriptional activity of WT1 Denys-Drash mutant proteins. Biochemical and Biophysical Research Communications, 233 (3), 723-728. doi: 10.1006/bbrc.1997.6545 |
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1997 Journal Article No evidence of mutation in the human PTC gene, responsible for nevoid basal cell carcinoma syndrome, in human primary squamous cell carcinomas of the esophagus and lungSuzuki, K, Daigo, Y, Fukuda, S, Tokino, T, Isomura, M, Isono, K, Wainwright, B and Nakamura, Y (1997). No evidence of mutation in the human PTC gene, responsible for nevoid basal cell carcinoma syndrome, in human primary squamous cell carcinomas of the esophagus and lung. Japanese journal of cancer research : Gann, 88 (3), 225-8. doi: 10.1111/j.1349-7006.1997.tb00370.x |
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1997 Journal Article Pulsed-field gel electrophoresis and FISH mapping of chromosome 9q22: Placement of a novel zinc finger gene within the NBCCS and ESS1 regionLevanat, S, Chidambaram, A, Wicking, C, BrayWard, P, Pressman, C, Toftgard, R, Gailani, MR, Myers, JC, Wainwright, B, Dean, M and Bale, AE (1997). Pulsed-field gel electrophoresis and FISH mapping of chromosome 9q22: Placement of a novel zinc finger gene within the NBCCS and ESS1 region. Cytogenetics and Cell Genetics, 76 (3-4), 208-213. doi: 10.1159/000134551 |
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1997 Journal Article De novo mutations of the patched gene in nevoid basal cell carcinoma syndrome help to define the clinical phenotypeWicking, C., Gillies, S., Smyth, I., Shanley, S., Fowles, L., Ratcliffe, J., Wainwright, B. and Chenevix-Trench, G. (1997). De novo mutations of the patched gene in nevoid basal cell carcinoma syndrome help to define the clinical phenotype. American Journal of Medical Genetics Part A, 73 (3), 304-307. doi: 10.1002/(SICI)1096-8628(19971219)73:33.0.CO;2-N |
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1997 Journal Article Most germ-line mutations in the nevoid basal cell carcinoma syndrome lead to a premature termination of the PATCHED protein, and no genotype-phenotype correlations are evidentWicking, Carol, Shanley, Susan, Smyth, Ian, Gillies, Susan, Negus, Kylie, Graham, Scott, Suthers, Graeme, Haites, Neva, Edwards, Matt, Wainwright, Brandon and Chenevix-Trench, Georgia (1997). Most germ-line mutations in the nevoid basal cell carcinoma syndrome lead to a premature termination of the PATCHED protein, and no genotype-phenotype correlations are evident. American Journal of Human Genetics, 60 (1), 21-26. |
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1996 Journal Article Targeted disruption of the Wnt2 gene results in placentation defectsMonkley, Susan J., Delaney, Stephen J., Pennisi, David J., Christiansen, Jeffrey H. and Wainwright, Brandon J. (1996). Targeted disruption of the Wnt2 gene results in placentation defects. Development, 122 (11), 3343-3353. doi: 10.1242/dev.122.11.3343 |
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1996 Journal Article A demonstration using mouse models that successful gene therapy for cystic fibrosis requires only partial gene correctionDorin, J. R., Farley, R., Webb, S., Smith, S. N., Farini, E., Delaney, S. J., Wainwright, B. J., Alton, E. W.F.W. and Porteous, D. J. (1996). A demonstration using mouse models that successful gene therapy for cystic fibrosis requires only partial gene correction. Gene Therapy, 3 (9), 797-801. |
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1996 Journal Article A novel target for the Wilms' tumour suppressor protein (WT1) is bound by a unique combination of zinc fingersLittle, MH, Holmes, G, Pell, L, Caricasole, A, Duarte, A, Law, M, Ward, A and Wainwright, B (1996). A novel target for the Wilms' tumour suppressor protein (WT1) is bound by a unique combination of zinc fingers. Oncogene, 13 (7), 1461-1469. |
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1996 Journal Article Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndromeHahn, H, Wicking, C, Zaphiropoulos, PG, Gailani, MR, Shanley, S, Chidambaram, A, Vorechovsky, , Holmberg, E, Unden, AB, Gillies, S, Negus, K, Smyth, , Pressman, C, Leffell, DJ, Gerrard, B, Goldstein, AM, Dean, M, Toftgard, R, ChenevixTrench, G, Wainwright, B and Bale, AE (1996). Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome. Cell, 85 (6), 841-851. doi: 10.1016/S0092-8674(00)81268-4 |
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1996 Journal Article A mammalian patched homolog is expressed in target tissues of sonic hedgehog and maps to a region associated with developmental abnormalitiesHahn, Heidi, Christiansen, Jeffrey, Wicking, Carol, Zaphiropoulos, Peter G., Chidambaram, Abirami, Gerrard, Bernard, Vorechovsky, Igor, Bale, Allen E., Toftgard, Rune, Dean, Michael and Wainwright, Brandon (1996). A mammalian patched homolog is expressed in target tissues of sonic hedgehog and maps to a region associated with developmental abnormalities. Journal of Biological Chemistry, 271 (21), 12125-12128. doi: 10.1074/jbc.271.21.12125 |
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1996 Journal Article Cystic fibrosis mice carrying the missense mutation G551D replicate human genotype-phenotype correlationsDelaney, Stephen J., Alton, Eric W.F.W., Smith, Stephen N., Lunn, Dominic P., Farley, Ray, Lovelock, Paul K., Thomson, Scott A., Hume, David A., Lamb, David, Porteous, David J., Dorin, Julia R. and Wainwright, Brandon J. (1996). Cystic fibrosis mice carrying the missense mutation G551D replicate human genotype-phenotype correlations. EMBO Journal, 15 (5), 955-963. doi: 10.1002/j.1460-2075.1996.tb00432.x |
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1996 Journal Article Murine WNT11 is a secreted glycoprotein that morphologically transforms mammary epithelial cellsChristiansen J.H., Monkley S.J. and Wainwright B.J. (1996). Murine WNT11 is a secreted glycoprotein that morphologically transforms mammary epithelial cells. Oncogene, 12 (12), 2705-2711. |
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1996 Journal Article +P5(D1S3309E), a novel target binding site for the Wilms' tumour suppressor 1 (WT1) gene, maps to human chromosome 1q21->q22Negus, K, Holmes, GH, Wicking, C, Wainwright, BJ and Little, MH (1996). +P5(D1S3309E), a novel target binding site for the Wilms' tumour suppressor 1 (WT1) gene, maps to human chromosome 1q21->q22. Cytogenetics and Cell Genetics, 72 (4), 306-309. doi: 10.1159/000134210 |
