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2010

Journal Article

Canonical Notch signaling is not required for the growth of Hedgehog pathway-induced medulloblastoma

Julian, E., Dave, R. K., Robson, J. P., Hallahan, A. R. and Wainwright, B. J. (2010). Canonical Notch signaling is not required for the growth of Hedgehog pathway-induced medulloblastoma. Oncogene, 29 (24), 3465-3476. doi: 10.1038/onc.2010.101

Canonical Notch signaling is not required for the growth of Hedgehog pathway-induced medulloblastoma

2010

Journal Article

International network of cancer genome projects

Hudson, T. J., Anderson, W., Aretz, A., Barker, A. D., Grimmond, S. M., Pearson, J. V., Cloonan, N., Gardiner, B. A., Waddell, N. J., Wilson, P. J., Wainwright, B. J. and The International Cancer Genome Consortium (2010). International network of cancer genome projects. Nature, 464 (7291), 993-998. doi: 10.1038/nature08987

International network of cancer genome projects

2010

Journal Article

Wnt2 regulates progenitor proliferation in the developing ventral midbrain

Sousa, Kyle M., Villaescusa, J. Carlos, Cajanek, Lukas, Ondr, Jennifer K., Castelo-Branco, Goncalo, Hofstra, Wytske, Bryja, Vitezslav, Palmberg, Carina, Bergman, Tomas, Wainwright, Brandon, Lang, Richard A. and Arenas, Ernest (2010). Wnt2 regulates progenitor proliferation in the developing ventral midbrain. Journal of Biological Chemistry, 285 (10), 7246-7253. doi: 10.1074/jbc.M109.079822

Wnt2 regulates progenitor proliferation in the developing ventral midbrain

2009

Journal Article

Patched 1 is a crucial determinant of asymmetry and digit number in the vertebrate limb

Butterfield, N. C., Metzis, V, McGlinn, E, Bruce, S. J., Wainwright, B. J. and Wicking, C (2009). Patched 1 is a crucial determinant of asymmetry and digit number in the vertebrate limb. DEVELOPMENT, 136 (20), 3515-3524. doi: 10.1242/dev.037507

Patched 1 is a crucial determinant of asymmetry and digit number in the vertebrate limb

2009

Journal Article

The hedgehog receptor Patched1 regulates myeloid and lymphoid progenitors by distinct cell-extrinsic mechanisms

Siggins, S. L., Nguyen, N. Y. N., McCormack, M. P., Vasudevan, S, Villani, R, Jane, S. M., Wainwright, B. J. and Curtis, D. J. (2009). The hedgehog receptor Patched1 regulates myeloid and lymphoid progenitors by distinct cell-extrinsic mechanisms. BLOOD, 114 (5), 995-1004. doi: 10.1182/blood-2009-03-208330

The hedgehog receptor Patched1 regulates myeloid and lymphoid progenitors by distinct cell-extrinsic mechanisms

2009

Journal Article

Ptch1 is required locally for mammary gland morphogenesis and systemically for ductal elongation

Moraes, R. C., Chang, H, Harrington, N, Landua, J. D., Prigge, J. T., Lane, T. F., Wainwright, B. J., Hamel, P. A. and Lewis, M. T. (2009). Ptch1 is required locally for mammary gland morphogenesis and systemically for ductal elongation. DEVELOPMENT, 136 (9), 1423-1432. doi: 10.1242/dev.023994

Ptch1 is required locally for mammary gland morphogenesis and systemically for ductal elongation

2009

Journal Article

Patched1 deletion increases N-Myc protein stability as a mechanism of medulloblastoma initiation and progression

Thomas, W. D., Chen, J, Gao, Y. R., Cheung, B, Koach, J, Sekyere, E, Norris, M. D., Haber, M, Ellis, T, Wainwright, B and Marshall, G. M. (2009). Patched1 deletion increases N-Myc protein stability as a mechanism of medulloblastoma initiation and progression. ONCOGENE, 28 (13), 1605-1615. doi: 10.1038/onc.2009.3

Patched1 deletion increases N-Myc protein stability as a mechanism of medulloblastoma initiation and progression

2009

Conference Publication

The interaction of Sonic Hedgehog and Notch signalling in medulloblastoma

Haase, E, Hallahan, A and Wainwright, B (2009). The interaction of Sonic Hedgehog and Notch signalling in medulloblastoma. 16th Annual Conference of the International-Society-of-Development-Biologists, Edinburgh Scotland, Sep 06-10, 2009. AMSTERDAM: ELSEVIER SCIENCE BV. doi: 10.1016/j.mod.2009.06.496

The interaction of Sonic Hedgehog and Notch signalling in medulloblastoma

2008

Journal Article

Targeted disruption of Brca1 in restricted compartments of the mouse mammary epithelia

Smart, Chanel E., Clarke, Catherine, Brooks, Kelly M., Raghavendra, Ashwini, Brewster, Brooke L., French, Juliet D., Hetherington, Rehan, Fleming, Jean S., Rothnagel, Joseph A., Wainwright, Brandon, Lakhani, Sunil R. and Brown, Melissa A. (2008). Targeted disruption of Brca1 in restricted compartments of the mouse mammary epithelia. Breast Cancer Research and Treatment, 112 (2), 237-241. doi: 10.1007/s10549-007-9859-2

Targeted disruption of Brca1 in restricted compartments of the mouse mammary epithelia

2008

Journal Article

Medulloblastoma can be initiated by deletion of Patched in lineage-restricted progenitors or stem cells

Yang, Zeng-Jie, Ellis, Tammy L., Markant, Shirley L., Read, Tracy-Ann, Kessler, Jessica D, Melissa Bourboulas, Schuller, Ulrich, Machold, Robert, Fishell, Gord, Rowitch, David H., Wainwright, Brandon J. and Wechsler-Reya, Robert J. (2008). Medulloblastoma can be initiated by deletion of Patched in lineage-restricted progenitors or stem cells. Cancer Cell, 14 (2), 135-145. doi: 10.1016/j.ccr.2008.07.003

Medulloblastoma can be initiated by deletion of Patched in lineage-restricted progenitors or stem cells

2008

Journal Article

Expression of the NET family member Zfp503 is regulated by hedgehog and BMP signaling in the limb

McGlinn, Edwina, Richman, Joy M., Metzis, Vicki, Town, Liam, Butterfield, Natalie C., Wainwright, Brandon J. and Wicking, Carol (2008). Expression of the NET family member Zfp503 is regulated by hedgehog and BMP signaling in the limb. Developmental Dynamics, 237 (4), 1172-1182. doi: 10.1002/dvdy.21508

Expression of the NET family member Zfp503 is regulated by hedgehog and BMP signaling in the limb

2008

Journal Article

Sonic Hedgehog regulates Hes1 through a novel mechanism that is independent of canonical Notch pathway signalling

Ingram, W. J., McCue, K. I., Tran, T. H., Hallahan, A. R. and Wainwright, B. J. (2008). Sonic Hedgehog regulates Hes1 through a novel mechanism that is independent of canonical Notch pathway signalling. Oncogene, 27 (10), 1489-1500. doi: 10.1038/sj.onc.1210767

Sonic Hedgehog regulates Hes1 through a novel mechanism that is independent of canonical Notch pathway signalling

2008

Journal Article

Nasal abnormalities in cystic fibrosis mice independent of infection and inflammation

Hilliard, Tom N., Zhu, Jie, Farley, Ray, Escudero-Garcia, Sara, Wainwright, Brandon J., Jeffery, Peter K., Griesenbach, Uta, Bush, Andrew, Davies, Jane C. and Alton, Eric W. F. W. (2008). Nasal abnormalities in cystic fibrosis mice independent of infection and inflammation. American Journal of Respiratory Cell and Molecular Biology, 39 (1), 19-25. doi: 10.1165/rcmb.2007-0284OC

Nasal abnormalities in cystic fibrosis mice independent of infection and inflammation

2007

Journal Article

Novel neutrophil-derived proteins in bronchoalveolar lavage fluid indicate an exaggerated inflammatory response in pediatric cystic fibrosis patients

McMorran, Brendan J., Patat, Severine A. Ouvry, Carlin, John B., Grimwood, Keith, Jones, Alun, Armstrong, David S., Galati, John C., Cooper, Peter J., Byrnes, Catherine A., Francis, Paul W., Robertson, Colin F., Hume, David A., Borchers, Christoph H., Wainwright, Claire E. and Wainwright, Brandon J. (2007). Novel neutrophil-derived proteins in bronchoalveolar lavage fluid indicate an exaggerated inflammatory response in pediatric cystic fibrosis patients. Clinical Chemistry, 53 (10), 1782-1791. doi: 10.1373/clinchem.2007.087650

Novel neutrophil-derived proteins in bronchoalveolar lavage fluid indicate an exaggerated inflammatory response in pediatric cystic fibrosis patients

2007

Conference Publication

Targeted disruption of Brca1 in restricted compartments of the mouse mammary epithelia

Smart, C. E., Clarke, C., Brooks, K. M., Raghavendra, A., Brewster, B. L., French, J. D., Hetherington, R., Fleming, J. S., Rothnagel, J. A., Wainwright, B., Lakhani, S. R. and Brown, M. A. (2007). Targeted disruption of Brca1 in restricted compartments of the mouse mammary epithelia. Australian Breast Cancer Conference, Melbourne, Australia, 2007.

Targeted disruption of Brca1 in restricted compartments of the mouse mammary epithelia

2007

Journal Article

Chimeric constructs endow the human CFTR Cl(-)channel with the gating behavior of murine CFTR

Scott-Ward, T. S., Cai, Z. W., Dawson, E. S., Doherty, A., Da Paula, A. C., Davidson, H., Porteous, D. J., Wainwright, B. J., Amaral, M. D., Sheppard, D. N. and Boyd, A. C. (2007). Chimeric constructs endow the human CFTR Cl(-)channel with the gating behavior of murine CFTR. Proceedings of The National Academy of Sciences of The United States of America, 104 (41), 16365-16370. doi: 10.1073/pnas.0701562104

Chimeric constructs endow the human CFTR Cl(-)channel with the gating behavior of murine CFTR

2007

Journal Article

Wnt2 coordinates the commitment of mesoderm to hematopoietic, endothelial, and cardiac lineages in embryoid bodies

Wang, H., Gilner, J. B., Bautch, V. L., Wang, D. Z., Wainwright, B. J., Kirby, S. L. and Patterson, C. (2007). Wnt2 coordinates the commitment of mesoderm to hematopoietic, endothelial, and cardiac lineages in embryoid bodies. Journal of Biological Chemistry, 282 (1), 782-791. doi: 10.1074/jbc.M606610200

Wnt2 coordinates the commitment of mesoderm to hematopoietic, endothelial, and cardiac lineages in embryoid bodies

2007

Conference Publication

Targeted disruption of Brca1 in restricted compartments of the mouse mammary epithelia

Brewster, Brooke, Brooke, Kelly, Brown, Melissa Anne, Clarke, C., Fleming, J. S., French, J. D., Hetherington, Rehan, Lakhani, Sunil, Raghavendra, Ashwini, Rothnagel, Joseph, Smart, Chanel and Wainwright, Brandon (2007). Targeted disruption of Brca1 in restricted compartments of the mouse mammary epithelia. kConFab Familial Breast Cancer Conference, Couran Cove, Queensland, 21-24 August 2007.

Targeted disruption of Brca1 in restricted compartments of the mouse mammary epithelia

2007

Journal Article

Sendai virus-mediated CFTR gene transfer to the airway epithelium

Ferrari, S., Griesenbach, U., Iida, A., Farley, R., Wright, A. M., Zhu, J., Munkonge, F. M., Smith, S. N., You, J., Ban, H., Inoue, M., Chan, M., Singh, C., Verdon, B., Argent, B. E., Wainwright, B., Jeffery, P. K., Geddes, D. M., Porteous, D. J., Hyde, S. C., Gray, M. A., Hasegawa, M. and Alton, E. W. F. W. (2007). Sendai virus-mediated CFTR gene transfer to the airway epithelium. Gene Therapy, 14 (19), 1371-1379. doi: 10.1038/sj.gt.3302991

Sendai virus-mediated CFTR gene transfer to the airway epithelium

2007

Conference Publication

Targeted disruption of Brca1 in restricted compartments of the mouse mammary epithelia

Brewster, Brooke, Brooks, Kelly, Brown, Melissa Anne, Clarke, C., Fleming, J. S., French, J. D., Hetherington, Rehan, Lakhani, Sunil, Raghavendra, Ashwini, Rothnagel, Joseph, Smart, Chanel and Wainwright, Brandon (2007). Targeted disruption of Brca1 in restricted compartments of the mouse mammary epithelia. Gordon Research Conference: Mammary Gland Biology, Newport, RI, 10-15 June 2007.

Targeted disruption of Brca1 in restricted compartments of the mouse mammary epithelia