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2018 Journal Article Flavonols and flavones - protecting against myocardial ischemia/reperfusion injury by targeting protein kinasesWoodman, Owen L., Chin, Kai Yee, Thomas, Colleen J., Ng, Dominic C. H. and May, Clive N. (2018). Flavonols and flavones - protecting against myocardial ischemia/reperfusion injury by targeting protein kinases. Current Medicinal Chemistry, 25 (34), 4402-4415. doi: 10.2174/0929867325666180326161730 |
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2018 Journal Article Factors that influence adult neurogenesis as potential therapyShohayeb, Belal, Diab, Mohamed, Ahmed, Mazen and Ng, Dominic Chi Hiung (2018). Factors that influence adult neurogenesis as potential therapy. Translational Neurodegeneration, 7 (1) 4, 1-19. doi: 10.1186/s40035-018-0109-9 |
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2018 Journal Article Protection against reperfusion injury by 3',4'-dihydroxyflavonol in rat isolated hearts involves inhibition of phospholamban and JNK2Chin, Kai Yee, Silva, Lokugan S., Darby, Ian A., Ng, Dominic C. H. and Woodman, Owen L. (2018). Protection against reperfusion injury by 3',4'-dihydroxyflavonol in rat isolated hearts involves inhibition of phospholamban and JNK2. International Journal of Cardiology, 254, 265-271. doi: 10.1016/j.ijcard.2017.11.101 |
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2017 Journal Article The Role of WD40-Repeat Protein 62 (MCPH2) in Brain Growth: Diverse Molecular and Cellular Mechanisms Required for Cortical DevelopmentShohayeb, Belal, Lim, Nicholas Rui, Ho, Uda, Xu, Zhiheng, Dottori, Mirella, Quinn, Leonie and Ng, Dominic Chi Hiung (2017). The Role of WD40-Repeat Protein 62 (MCPH2) in Brain Growth: Diverse Molecular and Cellular Mechanisms Required for Cortical Development. Molecular Neurobiology, 55 (7), 5409-5424. doi: 10.1007/s12035-017-0778-x |
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2017 Journal Article Dynamic microtubule association of Doublecortin X (DCX) is regulated by its C-terminusMoslehi, Maryam, Ng, Dominic C. H. and Bogoyevitch, Marie A. (2017). Dynamic microtubule association of Doublecortin X (DCX) is regulated by its C-terminus. Scientific Reports, 7 (1) 5245, 5245. doi: 10.1038/s41598-017-05340-x |
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2017 Journal Article Glial-specific functions of microcephaly protein WDR62 and interaction with the mitotic kinase AURKA are essential for Drosophila brain growthLim, Nicholas R., Shohayeb, Belal, Zaytseva, Olga, Mitchell, Naomi, Millard, S. Sean, Ng, Dominic C. H. and Quinn, Leonie M. (2017). Glial-specific functions of microcephaly protein WDR62 and interaction with the mitotic kinase AURKA are essential for Drosophila brain growth. Stem Cell Reports, 9 (1), 32-41. doi: 10.1016/j.stemcr.2017.05.015 |
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2017 Journal Article Stathmin mediates neuroblastoma metastasis in a tubulin-independent manner via RhoA/ROCK signaling and enhanced transendothelial migrationFife, C. M., Sagnella, S. M., Teo, W. S., Po'Uha, S. T., Byrne, F. L., Yeap, Y. Y. C., Ng, D. C. H., Davis, T. P., McCarroll, J. A. and Kavallaris, M. (2017). Stathmin mediates neuroblastoma metastasis in a tubulin-independent manner via RhoA/ROCK signaling and enhanced transendothelial migration. Intensive Care Medicine, 36 (4), 501-511. doi: 10.1038/onc.2016.220 |
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2017 Journal Article WDR62 regulates early neural and glial progenitor specification of human pluripotent stem cellsAlshawaf, Abdulah J., Antonic, Ana, Skafidas, Efstratios, Ng, Dominic Chi-Hung and Dottori, Mirella (2017). WDR62 regulates early neural and glial progenitor specification of human pluripotent stem cells. Stem Cells International, 2017 7848932, 7848932-9. doi: 10.1155/2017/7848932 |
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2016 Journal Article A beacon of hope in stroke therapy - blockade of pathologically activated cellular events in excitotoxic neuronal death as potential neuroprotective strategiesHoque, Ashfaqul, Hossain, M. Iqbal, Ameen, S. Sadia, Ang, Ching-Seng, Williamson, Nicholas, Ng, Dominic C. H., Chueh, Anderly C., Roulston, Carli and Cheng, Heung-Chin (2016). A beacon of hope in stroke therapy - blockade of pathologically activated cellular events in excitotoxic neuronal death as potential neuroprotective strategies. Pharmacology and Therapeutics, 160, 159-179. doi: 10.1016/j.pharmthera.2016.02.009 |
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2016 Journal Article A large dataset of protein dynamics in the mammalian heart proteomeLau, Edward, Cao, Quan, Ng, Dominic C. M., Bleakley, Brian J., Dincer, T. Umut, Bot, Brian M., Wang, Ding, Liem, David A., Lam, Maggie P. Y., Ge, Junbo and Ping, Peipei (2016). A large dataset of protein dynamics in the mammalian heart proteome. Scientific Data, 3 (1) 160015. doi: 10.1038/sdata.2016.15 |
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2016 Journal Article Aurora A phosphorylation of WD40-repeat protein 62 in mitotic spindle regulationLim, Nicholas R., Yeap, Yvonne Y. C., Ang, Ching-Seng, Williamson, Nicholas A., Bogoyevitch, Marie A., Quinn, Leonie M. and Ng, Dominic C. H. (2016). Aurora A phosphorylation of WD40-repeat protein 62 in mitotic spindle regulation. Cell Cycle, 15 (3), 413-424. doi: 10.1080/15384101.2015.1127472 |
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2015 Journal Article Evidence that the MEK/ERK but not the PI3K/Akt pathway is required for protection from myocardial ischemia-reperfusion injury by 3′,4′-dihydroxyflavonolThomas, Colleen J., Lim, Nicholas R., Kedikaetswe, Alphious, Yeap, Yvonne Y., Woodman, Owen L., Ng, Dominic C. H. and May, Clive N. (2015). Evidence that the MEK/ERK but not the PI3K/Akt pathway is required for protection from myocardial ischemia-reperfusion injury by 3′,4′-dihydroxyflavonol. European Journal of Pharmacology, 758, 53-59. doi: 10.1016/j.ejphar.2015.03.054 |
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2015 Journal Article Loss of miR-223 and JNK signaling contribute to elevated Stathmin in malignant pleural mesotheliomaBirnie, Kimberly A., Yip, Yan Y., Ng, Dominic C. H., Kirschner, Michaela B., Reid, Glen, Prele, Cecilia M., Musk, Arthur W. (Bill), Lee, Y. C. Gary, Thompson, Philip J., Mutsaers, Steven E. and Badrian, Bahareh (2015). Loss of miR-223 and JNK signaling contribute to elevated Stathmin in malignant pleural mesothelioma. Molecular Cancer Research, 13 (7), 1106-1118. doi: 10.1158/1541-7786.MCR-14-0442 |
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2015 Journal Article Cardiac CaMKIIδ splice variants exhibit target signaling specificity and confer sex-selective arrhythmogenic actions in the ischemic-reperfused heartBell, James R., Raaijmakers, Antonia J. A., Curl, Claire L., Reichelt, Melissa E., Harding, TristanW., Bei, Aier, Ng, Dominic C. H., Erickson, Jeffrey R., Petroff, Martin Vila, Harrap, Stephen B. and Delbridge, Lea M. D. (2015). Cardiac CaMKIIδ splice variants exhibit target signaling specificity and confer sex-selective arrhythmogenic actions in the ischemic-reperfused heart. International Journal of Cardiology, 181, 288-296. doi: 10.1016/j.ijcard.2014.11.159 |
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2015 Journal Article Dual role of Src kinase in governing neuronal survivalHossaina, M. Iqbal, Hoquel, Ashfaqul, Lessene, Guillaume, Kamaruddin, M. Aizuddin, Chu, Percy W. Y., Ng, Ivan H. W., Irtegun, Sevgi, Ng, Dominic C. H., Bogoyevitch, Marie A., Burgess, Antony W., Hill, Andrew F. and Cheng, Heung-Chin (2015). Dual role of Src kinase in governing neuronal survival. Brain Research, 1594, 1-14. doi: 10.1016/j.brainres.2014.10.040 |
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2015 Journal Article Opposing roles for JNK and Aurora A in regulating the association of WDR62 with spindle microtubulesLim, Nicholas R., Yeap, Yvonne Y. C., Zhao, Teresa T., Yip, Yan Y., Wong, Shu C., Xu, Dan, Ang, Ching-Seng, Williamson, Nicholas A., Xu, Zhiheng, Bogoyevitch, Marie A. and Ng, Dominic C. H. (2015). Opposing roles for JNK and Aurora A in regulating the association of WDR62 with spindle microtubules. Journal of Cell Science, 128 (3), 527-540. doi: 10.1242/jcs.157537 |
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2014 Journal Article Lysine ubiquitination and acetylation of human cardiac 20S proteasomesZong, Nobel, Ping, Peipei, Lau, Edward, Choi, Howard J. H., Ng, Dominic C. M., Meyer, David, Fang, Caiyun, Li, Haomin, Wang, Ding, Zelaya, Ivette M., Yates, John R. and Lam, Maggie P. Y. (2014). Lysine ubiquitination and acetylation of human cardiac 20S proteasomes. Proteomics Clinical Applications, 8 (7-8), 590-594. doi: 10.1002/prca.201400029 |
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2014 Journal Article Characterization of human plasma proteome dynamics using deuterium oxideWang, Ding, Liem, David A., Lau, Edward, Ng, Dominic C. M., Bleakley, Brian J., Cadeiras, Martin, Deng, Mario C., Lam, Maggie P. Y. and Ping, Peipei (2014). Characterization of human plasma proteome dynamics using deuterium oxide. Proteomics Clinical Applications, 8 (7-8), 610-619. doi: 10.1002/prca.201400038 |
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2014 Journal Article Differences in c-Jun N-terminal kinase recognition and phosphorylation of closely related stathmin-family membersYip, Yan Y., Yeap, Yvonne Y. C., Bogoyevitch, Marie A. and Ng, Dominic C. H. (2014). Differences in c-Jun N-terminal kinase recognition and phosphorylation of closely related stathmin-family members. Biochemical and Biophysical Research Communications, 446 (1), 248-254. doi: 10.1016/j.bbrc.2014.02.101 |
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2014 Journal Article Intracellular mobility and nuclear trafficking of the stress-activated kinase JNK1 are impeded by hyperosmotic stressMisheva, Mariya, Kaur, Gurpreet, Ngoei, Kevin R. W., Yeap, Yvonne Y., Ng, Ivan H. W., Wagstaff, Kylie M., Ng, Dominic C. H., Jans, David A. and Bogoyevitch, Marie A. (2014). Intracellular mobility and nuclear trafficking of the stress-activated kinase JNK1 are impeded by hyperosmotic stress. BBA- Molecular Cell Research, 1843 (2), 253-264. doi: 10.1016/j.bbamcr.2013.10.017 |
