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2026 Journal Article Utilizing biorecognition to prime tumors for enhanced nanomedicine delivery of alpha therapiesFletcher, Nicholas L., Chu, Weijing, Huda, Pie, Prior, Amber, S., Gayathri, Humphries, James, Howard, Christopher, Wood, James L., Zhang, Xiaoyan, Silva, Marina Silveira E., Lum, Benedict, Lim, Malcolm, Simpson, Fiona and Thurecht, Kristofer J. (2026). Utilizing biorecognition to prime tumors for enhanced nanomedicine delivery of alpha therapies. Journal of Controlled Release, 392 114708, 114708. doi: 10.1016/j.jconrel.2026.114708 |
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2026 Journal Article SPECT Imaging with Bifunctional Technetium-99m Nitrido Bis(thiosemicarbazonato) Complexes Tethered to Inhibitors of the Prostate-Specific Membrane AntigenMaclean, Rachel C., Fletcher, Nicholas L., Chu, Weijing, Lim, Ting Xiang, Tuck, Kellie L. and Paterson, Brett M. (2026). SPECT Imaging with Bifunctional Technetium-99m Nitrido Bis(thiosemicarbazonato) Complexes Tethered to Inhibitors of the Prostate-Specific Membrane Antigen. Molecular Pharmaceutics acs.molpharmaceut.5c01804. doi: 10.1021/acs.molpharmaceut.5c01804 |
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2026 Journal Article Trans-endothelial trafficking in zebrafish: nanobio interactions of polyethylene glycol-based nanoparticles in live vasculatureLim, Ye-Wheen, Bell, Craig A., Fletcher, Nicholas L., Condon, Nicholas D., Akhter, Dewan T., Rae, James, Ferguson, Charles, Martel, Nick, Humphries, James, Lo, Harriet P., Wu, Yeping, Houston, Zachary H., Lagendijk, Anne K., Hall, Thomas E., Thurecht, Kristofer J. and Parton, Robert G. (2026). Trans-endothelial trafficking in zebrafish: nanobio interactions of polyethylene glycol-based nanoparticles in live vasculature. ACS Nano, 20 (3), 3132-3155. doi: 10.1021/acsnano.5c21042 |
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2026 Journal Article Synthesis and Evaluation of D8W, an Octadentate Desferrioxamine Analogue with Enhanced Water Solubility Designed for 89 Zr-ImmunoPET ImagingWood, James L., Ghosh, Saikat, Rosser, Callum A., Feeney, Samuel V., Brown, Christopher J. M., Fletcher, Nicholas L., Wheatcroft, Michael P., Thurecht, Kristofer J. and Codd, Rachel (2026). Synthesis and Evaluation of D8W, an Octadentate Desferrioxamine Analogue with Enhanced Water Solubility Designed for 89 Zr-ImmunoPET Imaging. Molecular Pharmaceutics, 23 (3) acs.molpharmaceut.5c01947, 1-14. doi: 10.1021/acs.molpharmaceut.5c01947 |
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2026 Journal Article Pretargeted polymeric systems for conducting chemo-radiotherapy on glioblastoma: an evaluation of the impact of nanomedicine structure on bioorthogonal chemistry in vivoChu, Weijing, Ediriweera, Gayathri R., Prior, Amber, Huda, Pie, Lum, Benedict, Howard, Christopher B., Fletcher, Nicholas L., Bernhardt, Paul V. and Thurecht, Kristofer J. (2026). Pretargeted polymeric systems for conducting chemo-radiotherapy on glioblastoma: an evaluation of the impact of nanomedicine structure on bioorthogonal chemistry in vivo. Biomacromolecules, 27 (1), 205-216. doi: 10.1021/acs.biomac.5c01157 |
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2025 Journal Article A modular encapsulation system for precision delivery of proteins, nucleic acids, and small moleculesLuong, Thai D., Martel, Nick, Rae, James, Lo, Harriet P., Lim, Ye-Wheen, Wu, Yeping, McMahon, Kerrie-Ann, Sun, Haolan, Fletcher, Nicholas L., Thurecht, Kristofer J., Johnston, Angus P. R., Ariotti, Nicholas, Hall, Thomas E. and Parton, Robert G. (2025). A modular encapsulation system for precision delivery of proteins, nucleic acids, and small molecules. ACS Nano, 19 (50), 42079-42096. doi: 10.1021/acsnano.5c11452 |
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2025 Journal Article PEG-free lipid nanoparticles for mRNA delivery: superhydrophilic sulfoxide polymer coatingsChoy, On Ting, Fletcher, Nicholas L., Fu, Changkui, Vu, Mai N., Ediriweera, Gayathri R., Humphries, James, Hu, Mingdi, Kent, Stephen J., Cai, Rong, Chen, Chunying and Whittaker, Andrew K. (2025). PEG-free lipid nanoparticles for mRNA delivery: superhydrophilic sulfoxide polymer coatings. Biomacromolecules, 27 (1) acs.biomac.5c01899, 624-639. doi: 10.1021/acs.biomac.5c01899 |
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2025 Conference Publication Development of thiosemicarbazonato technetium-99m complexes for SPECT imagingMaclean, Rachel, Fletcher, Nicholas, Alsadig, Ahmed, Chu, Weijing, Sihver, Wiebke, Baraban, Larysa, Thurecht, Kristofer, Kubeil, Manja, Tuck, Kellie and Paterson, Brett (2025). Development of thiosemicarbazonato technetium-99m complexes for SPECT imaging. International Symposium on Radiopharmaceutical Sciences iSRS 2025, Gold Coast, QLD, Australia, 11-15 May 2025. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.nucmedbio.2025.109249 |
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2025 Conference Publication D2 – Enabling a theranostic approach with 89Zr/177Lu in a single trifunctional ligand scaffoldWood, James, Ghosh, Saikat, Houston, Zachary, Fletcher, Nicholas, Humphries, James, Mardon, Karine, Akhter, Dewan, Tieu, William, Ivashkevich, Alesia, Wheatcroft, Michael, Thurecht, Kristofer and Codd, Rachel (2025). D2 – Enabling a theranostic approach with 89Zr/177Lu in a single trifunctional ligand scaffold. International Symposium on Radiopharmaceutical Sciences iSRS 2025, Gold Coast, QLD, Australia, 11-15 May 2025. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.nucmedbio.2025.109244 |
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2025 Journal Article Preclinical evaluation of [212Pb]Pb-ADVC001: a prostate-specific membrane antigen–targeted α-therapy for prostate cancerLiu, Feifei, Monterosso, Melissa E., Boucher, Didier, Shakti, Stelle, Li, Kwong Ching, Kim, Chanwoo, Prior, Amber, Sydes, Abby, Soderholm, Amelia T., Fletcher, Nicholas, Akhter, Dewan, Thurecht, Kristofer, Tieu, William, Kuan, Kevin, Horsfall, Aimee, Kumar, Saawan, Koehbach, Johannes, Hammond, Edward, Karmann, Anna, Rose, Stephen, Li, Gary, Puttick, Simon and Kryza, Thomas (2025). Preclinical Evaluation of [212Pb]Pb-ADVC001: A Prostate-Specific Membrane Antigen–Targeted α-Therapy for Prostate Cancer. Journal of Nuclear Medicine, 66 (11), jnumed.125.269707-1713. doi: 10.2967/jnumed.125.269707 |
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2025 Conference Publication Targeting the oxytocin receptor for breast cancer imaging and radiotherapyMuttenthaler, Markus, Perisic, Monika, Liu, Huiping, Kalaba, Predrag, Madge, Harrison, Dighe, Satish, Fletcher, Nicholas, Migotto, Mary-Anne, Mardon, Karine, Thurecht, Kristofer, Keimpema, Erik and Gruber, Christian (2025). Targeting the oxytocin receptor for breast cancer imaging and radiotherapy. International Symposium on Radiopharmaceutical Sciences iSRS 2025, Gold Coast, QLD, Australia, 11-15 May 2025. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.nucmedbio.2025.109302 |
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2025 Conference Publication Pre-targeting of PEG-based nanomedicines: precise delivery of potent payloadsFletcher, Nicholas, Thurecht, Kristofer, Chu, Weijing, Huda, Pie, Humphries, James and Wood, James (2025). Pre-targeting of PEG-based nanomedicines: precise delivery of potent payloads. International Symposium on Radiopharmaceutical Sciences iSRS 2025, Gold Coast, QLD, Australia, 11-15 May 2025. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.nucmedbio.2025.109150 |
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2025 Conference Publication Development of novel MnO2-based nanoparticles for PET/MRI-guided Alpha TherapyGulzar, Arif, Wang, Yanan, Balaji, Arunpandian, Fletcher, Nicholas and Thurecht, Kristofer (2025). Development of novel MnO2-based nanoparticles for PET/MRI-guided Alpha Therapy. International Symposium on Radiopharmaceutical Sciences iSRS 2025, Gold Coast, QLD Australia, 11-15 May 2025. Elsevier BV. doi: 10.1016/j.nucmedbio.2025.109532 |
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2025 Conference Publication Trifunctional albumin-binding constructs for optimisation of in vivo delivery of cancer radio-theranosticsHe, Xie (Kate), Thurecht, Kristofer, Fletcher, Nicholas, Bell, Craig and Kempe, Kristian (2025). Trifunctional albumin-binding constructs for optimisation of in vivo delivery of cancer radio-theranostics. International Symposium on Radiopharmaceutical Sciences iSRS 2025, Gold Coast, QLD, Australia, 11-15 May 2025. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.nucmedbio.2025.109457 |
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2025 Journal Article Development of a novel engineered antibody format for PSMA-targeted radionuclide therapyFletcher, Nicholas L., Houston, Zachary H., Chandler, Peter G., Yan, Eddie, Holgate, Rob, Wheatcroft, Michael and Thurecht, Kristofer J. (2025). Development of a novel engineered antibody format for PSMA-targeted radionuclide therapy. Molecular Pharmaceutics, 22 (7), 3666-3678. doi: 10.1021/acs.molpharmaceut.4c01193 |
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2025 Journal Article Immune-modulating nanomedicines for enhanced drug delivery to non-small-cell lung cancerLiu, Feifei, Howard, Christopher B., Huda, Pie, Fletcher, Nicholas L., Bell, Craig A., Blakey, Idriss, Agrez, Michael and Thurecht, Kristofer J. (2025). Immune-modulating nanomedicines for enhanced drug delivery to non-small-cell lung cancer. Biomaterials, 317 123089, 1-14. doi: 10.1016/j.biomaterials.2025.123089 |
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2025 Journal Article Receptor CDCP1 is a potential target for personalized imaging and treatment of poor outcome HER2+, triple negative and metastatic ER+/HER2- breast cancersGough, Madeline, Kwah, Kayden KX., Khan, Tashbib, Ghosh, Saikat, Sun, Biao, Lee, Catherine YJ., Sokolowski, Kamil A., Tse, Brian WC., Wickramasuriya, Lashith, Ferguson, Kaltin, Rogers, Rebecca, Goh, Justin B., Fletcher, Nicholas L., Houston, Zachary H., Thurecht, Kristofer J., Bray, Laura J., Liu, Cheng, Pyke, Christopher, Lim, Elgene, Snell, Cameron E., He, Yaowu, Hooper, John D. and Kryza, Thomas (2025). Receptor CDCP1 is a potential target for personalized imaging and treatment of poor outcome HER2+, triple negative and metastatic ER+/HER2- breast cancers. Clinical Cancer Research, 31 (8), 1504-1519. doi: 10.1158/1078-0432.ccr-24-2865 |
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2025 Journal Article Harnessing nanoparticles and bioorthogonal chemistries for improving precision of nuclear medicineEdiriweera, Gayathri R., Li, Mengdie, Fletcher, Nicholas L., Houston, Zachary H., Ahamed, Muneer, Blakey, Idriss and Thurecht, Kristofer J. (2025). Harnessing nanoparticles and bioorthogonal chemistries for improving precision of nuclear medicine. Biomaterials Science, 13 (9), 2297-2319. doi: 10.1039/d4bm01387e |
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2025 Book Chapter Multifunctional biocompatible hyperbranched polymers as molecular imaging agents and theranosticsBoase, Nathan R. B., Bell, Craig A., Fletcher, Nicholas L. and Thurecht, Kristofer J. (2025). Multifunctional biocompatible hyperbranched polymers as molecular imaging agents and theranostics. Biomedical nanotechnology. (pp. 69-106) edited by Cassandra Callmann. New York, NY USA: Humana New York. doi: 10.1007/978-1-0716-4402-7_5 |
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2025 Journal Article Lipid nanoparticles and transcranial focused ultrasound enhance the delivery of SOD1 antisense oligonucleotides to the murine brain for ALS therapyEdiriweera, Gayathri R., Sivaram, Amal J., Cowin, Gary, Brown, Mikayla L., McAlary, Luke, Lum, Jeremy S., Fletcher, Nicholas L., Robinson, Liam, Simpson, Joshua D., Chen, Liyu, Wasielewska, Joanna M., Byrne, Ella, Finnie, John W., Manavis, Jim, White, Anthony R., Yerbury, Justin J., Thurecht, Kristofer J. and Vine, Kara L. (2025). Lipid nanoparticles and transcranial focused ultrasound enhance the delivery of SOD1 antisense oligonucleotides to the murine brain for ALS therapy. Journal of Controlled Release, 378, 221-235. doi: 10.1016/j.jconrel.2024.11.074 |
