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2022 Journal Article Fracture hematoma micro-architecture influences transcriptional profile and plays a crucial role in determining bone healing outcomesWoloszyk, Anna, Tuong, Zewen K., Perez, Louis, Aguilar, Leonardo, Bankole, Abraham I., Evans, Christopher H. and Glatt, Vaida (2022). Fracture hematoma micro-architecture influences transcriptional profile and plays a crucial role in determining bone healing outcomes. Biomaterials Advances, 139 213027, 1-15. doi: 10.1016/j.bioadv.2022.213027 |
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2022 Journal Article A robust experimental and computational analysis framework at multiple resolutions, modalities and coveragesTran, M., Yoon, S., Teoh, M., Andersen, S., Lam, PY., Purdue, B. W., Raghubar, A., Hanson, S.J., Devitt, K., Jones, K., Walters, S., Monkman, J., Kulasinghe, A., Tuong, Z.K., Soyer, H.P., Frazer, I. H. and Nguyen, Q. (2022). A robust experimental and computational analysis framework at multiple resolutions, modalities and coverages. Frontiers in Immunology, 13 911873, 911873. doi: 10.3389/fimmu.2022.911873 |
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2022 Journal Article Group 3 innate lymphocytes make a distinct contribution to type 17 immunity in bladder defenceRiding, Alexandra M., Loudon, Kevin W., Guo, Andrew, Ferdinand, John R., Lok, Laurence S.C., Richoz, Nathan, Stewart, Andrew, Castro-Dopico, Tomas, Tuong, Zewen Kelvin, Fiancette, Remi, Bowyer, Georgina S., Fleming, Aaron, Gillman, Eleanor S., Suchanek, Ondrej, Mahbubani, Krishnaa T., Saeb-Parsy, Kourosh, Withers, David, Dougan, Gordan, Clare, Simon and Clatworthy, Menna R. (2022). Group 3 innate lymphocytes make a distinct contribution to type 17 immunity in bladder defence. iScience, 25 (7) 104660, 1-30. doi: 10.1016/j.isci.2022.104660 |
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2022 Journal Article Mapping the developing human immune system across organsSuo, Chenqu, Dann, Emma, Goh, Issac, Jardine, Laura, Kleshchevnikov, Vitalii, Park, Jong-Eun, Botting, Rachel A., Stephenson, Emily, Engelbert, Justin, Tuong, Zewen Kelvin, Polanski, Krzysztof, Yayon, Nadav, Xu, Chuan, Suchanek, Ondrej, Elmentaite, Rasa, Domínguez Conde, Cecilia, He, Peng, Pritchard, Sophie, Miah, Mohi, Moldovan, Corina, Steemers, Alexander S., Mazin, Pavel, Prete, Martin, Horsfall, Dave, Marioni, John C., Clatworthy, Menna R., Haniffa, Muzlifah and Teichmann, Sarah A. (2022). Mapping the developing human immune system across organs. Science, 376 (6597) eabo0510, eabo0510-+. doi: 10.1126/science.abo0510 |
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2022 Journal Article Cross-tissue immune cell analysis reveals tissue-specific features in humansDomínguez Conde, C., Xu, C., Jarvis, L. B., Rainbow, D. B., Wells, S. B., Gomes, T., Howlett, S. K., Suchanek, O., Polanski, K., King, H. W., Mamanova, L., Huang, N., Szabo, P. A., Richardson, L., Bolt, L., Fasouli, E. S., Mahbubani, K. T., Prete, M., Tuck, L., Richoz, N., Tuong, Z. K., Campos, L., Mousa, H. S., Needham, E. J., Pritchard, S., Li, T., Elmentaite, R., Park, J., Rahmani, E. ... Teichmann, S. A. (2022). Cross-tissue immune cell analysis reveals tissue-specific features in humans. Science, 376 (6594) eabl5197, eabl5197-+. doi: 10.1126/science.abl5197 |
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2022 Journal Article GIMAP6 regulates autophagy, immune competence, and inflammation in mice and humansYao, Yikun, Du Jiang, Ping, Chao, Brittany N., Cagdas, Deniz, Kubo, Satoshi, Balasubramaniyam, Arasu, Zhang, Yu, Shadur, Bella, NaserEddin, Adeeb, Folio, Les R., Schwarz, Benjamin, Bohrnsen, Eric, Zheng, Lixin, Lynberg, Matthew, Gottlieb, Simone, Leney-Greene, Michael A., Park, Ann Y., Tezcan, Ilhan, Akdogan, Ali, Gocmen, Rahsan, Onder, Sevgen, Rosenberg, Avi, Soilleux, Elizabeth J., Johnson, Errin, Jackson, Peter K., Demeter, Janos, Chauvin, Samuel D., Paul, Florian, Selbach, Matthias ... Lenardo, Michael J. (2022). GIMAP6 regulates autophagy, immune competence, and inflammation in mice and humans. Journal of Experimental Medicine, 219 (6) e20201405, 1-29. doi: 10.1084/jem.20201405 |
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2022 Journal Article In vivo labeling reveals continuous trafficking of TCF-1+ T cells between tumor and lymphoid tissueLi, Zhi, Tuong, Zewen K., Dean, Isaac, Willis, Claire, Gaspal, Fabrina, Fiancette, Rémi, Idris, Suaad, Kennedy, Bethany, Ferdinand, John R., Peñalver, Ana, Cabantous, Mia, Murtuza Baker, Syed, Fry, Jeremy W., Carlesso, Gianluca, Hammond, Scott A., Dovedi, Simon J., Hepworth, Matthew R., Clatworthy, Menna R. and Withers, David R. (2022). In vivo labeling reveals continuous trafficking of TCF-1+ T cells between tumor and lymphoid tissue. Journal of Experimental Medicine, 219 (6) e20210749, 1-27. doi: 10.1084/jem.20210749 |
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2022 Journal Article The impact of hypoxia on B cells in COVID-19Kotagiri, Prasanti, Mescia, Federica, Hanson, Aimee L., Turner, Lorinda, Bergamaschi, Laura, Peñalver, Ana, Richoz, Nathan, Moore, Stephen D., Ortmann, Brian M., Dunmore, Benjamin J., Morgan, Michael D., Tuong, Zewen Kelvin, Göttgens, Berthold, Toshner, Mark, Hess, Christoph, Maxwell, Patrick. H., Clatworthy, Menna. R., Nathan, James A., Bradley, John R., Lyons, Paul A., Burrows, Natalie and Smith, Kenneth G.C. (2022). The impact of hypoxia on B cells in COVID-19. eBioMedicine, 77 103878, 103878. doi: 10.1016/j.ebiom.2022.103878 |
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2022 Journal Article B cell receptor repertoire kinetics after SARS-CoV-2 infection and vaccinationKotagiri, Prasanti, Mescia, Federica, Rae, William M., Bergamaschi, Laura, Tuong, Zewen K., Turner, Lorinda, Hunter, Kelvin, Gerber, Pehuén P., Hosmillo, Myra, Hess, Christoph, Clatworthy, Menna R., Goodfellow, Ian G., Matheson, Nicholas J., McKinney, Eoin F., Wills, Mark R., Gupta, Ravindra K., Bradley, John R., Bashford-Rogers, Rachael J.M., Lyons, Paul A. and Smith, Kenneth G.C. (2022). B cell receptor repertoire kinetics after SARS-CoV-2 infection and vaccination. Cell Reports, 38 (7) 110393, 110393. doi: 10.1016/j.celrep.2022.110393 |
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2022 Journal Article Ulcerative colitis is characterized by a plasmablast-skewed humoral response associated with disease activityUzzan, Mathieu, Martin, Jerome C., Mesin, Luka, Livanos, Alexandra E., Castro-Dopico, Tomas, Huang, Ruiqi, Petralia, Francesca, Magri, Giuliana, Kumar, Shashi, Zhao, Qing, Rosenstein, Adam K., Tokuyama, Minami, Sharma, Keshav, Ungaro, Ryan, Kosoy, Roman, Jha, Divya, Fischer, Jeremy, Singh, Harpriya, Keir, Mary E., Ramamoorthi, Nandhini, Gorman, William E. O’, Cohen, Benjamin L., Rahman, Adeeb, Cossarini, Francesca, Seki, Akihiro, Leyre, Louise, Vaquero, Sonia Tejedor, Gurunathan, Sakteesh, Grasset, Emilie K. ... Mehandru, Saurabh (2022). Ulcerative colitis is characterized by a plasmablast-skewed humoral response associated with disease activity. Nature Medicine, 28 (4), 766-779. doi: 10.1038/s41591-022-01680-y |
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2022 Journal Article Secreted toxins from Staphylococcus aureus strains isolated from keratinocyte skin cancers mediate pro-tumorigenic inflammatory responses in the skinKrueger, Annika, Zaugg, Julian, Chisholm, Sarah, Linedale, Richard, Lachner, Nancy, Teoh, Siok Min, Tuong, Zewen K., Lukowski, Samuel W., Morrison, Mark, Soyer, H. Peter, Hugenholtz, Philip, Hill, Michelle M. and Frazer, Ian H. (2022). Secreted toxins from Staphylococcus aureus strains isolated from keratinocyte skin cancers mediate pro-tumorigenic inflammatory responses in the skin. Frontiers in Microbiology, 12 789042, 789042. doi: 10.3389/fmicb.2021.789042 |
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2022 Journal Article Epigenetics and tissue immunity—translating environmental cues into functional adaptations*Tuong, Zewen Kelvin, Stewart, Benjamin J., Guo, Shuang Andrew and Clatworthy, Menna R. (2022). Epigenetics and tissue immunity—translating environmental cues into functional adaptations*. Immunological Reviews, 305 (1), 111-136. doi: 10.1111/imr.13036 |
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2021 Journal Article Resolving the immune landscape of human prostate at a single-cell level in health and cancerTuong, Zewen Kelvin, Loudon, Kevin W., Berry, Brendan, Richoz, Nathan, Jones, Julia, Tan, Xiao, Nguyen, Quan, George, Anne, Hori, Satoshi, Field, Sarah, Lynch, Andy G., Kania, Katarzyna, Coupland, Paul, Babbage, Anne, Grenfell, Richard, Barrett, Tristan, Warren, Anne Y., Gnanapragasam, Vincent, Massie, Charlie and Clatworthy, Menna R. (2021). Resolving the immune landscape of human prostate at a single-cell level in health and cancer. Cell Reports, 37 (12) 110132, 110132. doi: 10.1016/j.celrep.2021.110132 |
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2021 Journal Article Aldehyde-driven transcriptional stress triggers an anorexic DNA damage responseMulderrig, Lee, Garaycoechea, Juan I., Tuong, Zewen K., Millington, Christopher L., Dingler, Felix A., Ferdinand, John R., Gaul, Liam, Tadross, John A., Arends, Mark J., O’Rahilly, Stephen, Crossan, Gerry P., Clatworthy, Menna R. and Patel, Ketan J. (2021). Aldehyde-driven transcriptional stress triggers an anorexic DNA damage response. Nature, 600 (7887), 158-163. doi: 10.1038/s41586-021-04133-7 |
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2021 Journal Article A model of impaired Langerhans cell maturation associated with HPV induced epithelial hyperplasiaTuong, Zewen K., Lukowski, Samuel W., Nguyen, Quan H., Chandra, Janin, Zhou, Chenhao, Gillinder, Kevin, Bashaw, Abate A., Ferdinand, John R., Stewart, Benjamin J., Teoh, Siok Min, Hanson, Sarah J., Devitt, Katharina, Clatworthy, Menna R., Powell, Joseph E. and Frazer, Ian H. (2021). A model of impaired Langerhans cell maturation associated with HPV induced epithelial hyperplasia. iScience, 24 (11) 103326, 103326. doi: 10.1016/j.isci.2021.103326 |
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2021 Journal Article B-cells are abnormal in psychosocial stress and regulate meningeal myeloid cell activationLynall, Mary-Ellen, Kigar, Stacey L., Lehmann, Michael L., DePuyt, Allison E., Tuong, Zewen Kelvin, Listwak, Samuel J., Elkahloun, Abdel G., Bullmore, Edward T., Herkenham, Miles and Clatworthy, Menna R. (2021). B-cells are abnormal in psychosocial stress and regulate meningeal myeloid cell activation. Brain, Behavior, and Immunity, 97, 226-238. doi: 10.1016/j.bbi.2021.08.002 |
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2021 Conference Publication Tissue-resident B cells orchestrate macrophage phenotype and function in non-lymphoid organsSuchanek, Ondrej, Ferdinand, John R., Wijeyesinghe, Sathi, Tuong, Zewen K., Clare, Simon, Rogers, Rachael Bashford, Chandra, Anita, Mahbubani, Krishnaa, Lawley, Trevor, Okkenhaug, Klaus, Masopust, David and Clatworthy, Menna R. (2021). Tissue-resident B cells orchestrate macrophage phenotype and function in non-lymphoid organs. HOBOKEN: WILEY. |
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2021 Journal Article IFN-γ critically enables the intratumoural infiltration of CXCR3+ CD8+ T cells to drive squamous cell carcinoma regressionZeng, Zhen, Veitch, Margaret, Kelly, Gabrielle A., Tuong, Zewen K., Cruz, Jazmina G., Frazer, Ian H. and Wells, James W. (2021). IFN-γ critically enables the intratumoural infiltration of CXCR3+ CD8+ T cells to drive squamous cell carcinoma regression. Cancers, 13 (9) 2131, 2131. doi: 10.3390/cancers13092131 |
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2021 Journal Article Antigen nonspecific induction of distinct regulatory T cell states in oncogene-driven hyperproliferative skinZhou, Chenhao, Tuong, Zewen Kelvin, Lukowski, Samuel Wieslaw, Chandra, Janin and Frazer, Ian H. (2021). Antigen nonspecific induction of distinct regulatory T cell states in oncogene-driven hyperproliferative skin. ImmunoHorizons, 5 (2), 102-116. doi: 10.4049/immunohorizons.2100006 |
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2021 Journal Article Manganese-doped silica-based nanoparticles promote the efficacy of antigen-specific immunotherapyChandra, Janin, Teoh, Siok Min, Kuo, Paula, Tolley, Lynn, Bashaw, Abate Assefa, Tuong, Zewen Kelvin, Liu, Yang, Chen, Zibin, Wells, James W., Yu, Chengzhong, Frazer, Ian H. and Yu, Meihua (2021). Manganese-doped silica-based nanoparticles promote the efficacy of antigen-specific immunotherapy. The Journal of Immunology, 206 (5), ji2000355-998. doi: 10.4049/jimmunol.2000355 |
