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2023 Journal Article Early human lung immune cell development and its role in epithelial cell fateBarnes, Josephine L., Yoshida, Masahiro, He, Peng, Worlock, Kaylee B., Lindeboom, Rik G. H., Suo, Chenqu, Pett, J. Patrick, Wilbrey-Clark, Anna, Dann, Emma, Mamanova, Lira, Richardson, Laura, Polanski, Krzysztof, Pennycuick, Adam, Allen-Hyttinen, Jessica, Herczeg, Iván T., Arzili, Romina, Hynds, Robert E., Teixeira, Vitor H., Haniffa, Muzlifah, Lim, Kyungtae, Sun, Dawei, Rawlins, Emma L., Oliver, Amanda J., Lyons, Paul A., Marioni, John C., Ruhrberg, Christiana, Tuong, Zewen Kelvin, Clatworthy, Menna R., Reading, James L. ... Nikolić, Marko Z. (2023). Early human lung immune cell development and its role in epithelial cell fate. Science Immunology, 8 (90) eadf9988, 1-18. doi: 10.1126/sciimmunol.adf9988 |
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2023 Journal Article Tissue-resident B cells orchestrate macrophage polarisation and functionSuchanek, Ondrej, Ferdinand, John R., Tuong, Zewen K., Wijeyesinghe, Sathi, Chandra, Anita, Clauder, Ann-Katrin, Almeida, Larissa N., Clare, Simon, Harcourt, Katherine, Ward, Christopher J., Bashford-Rogers, Rachael, Lawley, Trevor, Manz, Rudolf A., Okkenhaug, Klaus, Masopust, David and Clatworthy, Menna R. (2023). Tissue-resident B cells orchestrate macrophage polarisation and function. Nature Communications, 14 (1) 7081, 1-20. doi: 10.1038/s41467-023-42625-4 |
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2023 Journal Article Autoimmune uveitis in Behçet's disease and Vogt‐Koyanagi‐Harada disease differ in tissue immune infiltration and T cell clonalityKang, Hao, Sun, Hongjian, Yang, Yang, Tuong, Zewen K., Shu, Minglei, Wei, Yunbo, Zhang, Yu, Yu, Di and Tao, Yong (2023). Autoimmune uveitis in Behçet's disease and Vogt‐Koyanagi‐Harada disease differ in tissue immune infiltration and T cell clonality. Clinical and Translational Immunology, 12 (9) e1461, 1-17. doi: 10.1002/cti2.1461 |
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2023 Journal Article Atypical B cells and impaired SARS-CoV-2 neutralization following heterologous vaccination in the elderlyFerreira, Isabella A.T.M., Lee, Colin Y.C., Foster, William S., Abdullahi, Adam, Dratva, Lisa M., Tuong, Zewen Kelvin, Stewart, Benjamin J., Ferdinand, John R., Guillaume, Stephane M., Potts, Martin O.P., Perera, Marianne, Krishna, Benjamin A., Peñalver, Ana, Cabantous, Mia, Kemp, Steven A., Ceron-Gutierrez, Lourdes, Ebrahimi, Soraya, Lyons, Paul, Smith, Kenneth G.C., Bradley, John, Collier, Dami A., McCoy, Laura E., van der Klaauw, Agatha, Thaventhiran, James E.D., Farooqi, I. Sadaf, Teichmann, Sarah A., MacAry, Paul A., Doffinger, Rainer, Wills, Mark R. ... Gupta, Ravindra K. (2023). Atypical B cells and impaired SARS-CoV-2 neutralization following heterologous vaccination in the elderly. Cell Reports, 42 (8) 112991, 112991. doi: 10.1016/j.celrep.2023.112991 |
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2023 Journal Article A novel multifunctional radioprotective strategy using P7C3 as a countermeasure against ionizing radiation-induced bone lossWei, Fei, Tuong, Zewen Kelvin, Omer, Mahmoud, Ngo, Christopher, Asiatico, Jackson, Kinzel, Michael, Pugazhendhi, Abinaya Sindu, Khaled, Annette R., Ghosh, Ranajay and Coathup, Melanie (2023). A novel multifunctional radioprotective strategy using P7C3 as a countermeasure against ionizing radiation-induced bone loss. Bone Research, 11 (1) 34, 1-20. doi: 10.1038/s41413-023-00273-w |
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2023 Journal Article Distinct pathogenic roles for resident and monocyte-derived macrophages in lupus nephritis (vol 7, e159751, 2022)Richoz, Nathan, Tuong, Zewen K., Loudon, Kevin W., Patino-Martinez, Eduardo, Ferdinand, John R., Portet, Anais, Romo-Tena, Jorge, Bashant, Kathleen R., Thevenon, Emeline, Rucci, Francesca, Hoyler, Thomas, Junt, Tobias, Kaplan, Mariana J., Siegel, Richard M. and Clatworthy, Menna R. (2023). Distinct pathogenic roles for resident and monocyte-derived macrophages in lupus nephritis (vol 7, e159751, 2022). Jci Insight, 8 (10) e171762. doi: 10.1172/jci.insight.171762 |
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2023 Conference Publication Venous plexus-associated lymphoid hubs support meningeal humoral immunityZanluqui, Nagela Ghabdan, Fitzpatrick, Zachary, Rosenblum, Jared S., Tuong, Zewen Kelvin, Chandrashekhar, Vikram, Negro-Demontel, Maria Luciana, Allinson, Kieren S. J., Mastorakos, Panagiotis, Chittiboina, Prashant, Maric, Dragan, Donahue, Danielle, Ferdinand, John R., Portet, Anais, Penalver, Ana, Gillman, Eleanor, Zhuang, Zhengping, Clatworthy, Menna R. and McGavern, Dorian B. (2023). Venous plexus-associated lymphoid hubs support meningeal humoral immunity. Immunology 2023™ Meeting, Washington, DC United States, 11-15 May 2023. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.210.supp.76.23 |
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2023 Journal Article Dandelion uses the single-cell adaptive immune receptor repertoire to explore lymphocyte developmental originsSuo, Chenqu, Polanski, Krzysztof, Dann, Emma, Lindeboom, Rik G. H., Vilarrasa-Blasi, Roser, Vento-Tormo, Roser, Haniffa, Muzlifah, Meyer, Kerstin B., Dratva, Lisa M., Tuong, Zewen Kelvin, Clatworthy, Menna R. and Teichmann, Sarah A. (2023). Dandelion uses the single-cell adaptive immune receptor repertoire to explore lymphocyte developmental origins. Nature Biotechnology, 42 (1), 40-51. doi: 10.1038/s41587-023-01734-7 |
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2023 Journal Article Low-dose IL-2 enhances the generation of IL-10-producing immunoregulatory B cellsInaba, Akimichi, Tuong, Zewen Kelvin, Zhao, Tian X., Stewart, Andrew P., Mathews, Rebeccah, Truman, Lucy, Sriranjan, Rouchelle, Kennet, Jane, Saeb-Parsy, Kourosh, Wicker, Linda, Waldron-Lynch, Frank, Cheriyan, Joseph, Todd, John A., Mallat, Ziad and Clatworthy, Menna R. (2023). Low-dose IL-2 enhances the generation of IL-10-producing immunoregulatory B cells. Nature Communications, 14 (1) 2071, 1-11. doi: 10.1038/s41467-023-37424-w |
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2023 Journal Article Heparan sulfate regulates IL-21 bioavailability and signal strength that control germinal center B cell selection and differentiationChen, Zhian, Cui, Yanfang, Yao, Yin, Liu, Bo, Yunis, Joseph, Gao, Xin, Wang, Naiqi, Cañete, Pablo F., Tuong, Zewen Kelvin, Sun, Hongjian, Wang, Hao, Yang, Siling, Wang, Runli, Leong, Yew Ann, Simon Davis, David, Qin, Jiahuan, Liang, Kaili, Deng, Jun, Wang, Conan K., Huang, Yen-Hua, Roco, Jonathan A., Nettelfield, Sam, Zhu, Huaming, Xu, Huajun, Yu, Zhijia, Craik, David, Liu, Zheng, Qi, Hai, Parish, Christopher and Yu, Di (2023). Heparan sulfate regulates IL-21 bioavailability and signal strength that control germinal center B cell selection and differentiation. Science immunology, 8 (80) eadd1728, 1-17. doi: 10.1126/sciimmunol.add1728 |
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2023 Journal Article Dimensionality reduction under scrutinyYang, Yang, Tuong, Zewen K. and Yu, Di (2023). Dimensionality reduction under scrutiny. Nature Computational Science, 3 (1), 8-9. doi: 10.1038/s43588-022-00383-1 |
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2022 Journal Article A human fetal lung cell atlas uncovers proximal-distal gradients of differentiation and key regulators of epithelial fatesHe, Peng, Lim, Kyungtae, Sun, Dawei, Pett, Jan Patrick, Jeng, Quitz, Polanski, Krzysztof, Dong, Ziqi, Bolt, Liam, Richardson, Laura, Mamanova, Lira, Dabrowska, Monika, Wilbrey-Clark, Anna, Madissoon, Elo, Tuong, Zewen Kelvin, Dann, Emma, Suo, Chenqu, Goh, Isaac, Yoshida, Masahiro, Nikolić, Marko Z., Janes, Sam M., He, Xiaoling, Barker, Roger A., Teichmann, Sarah A., Marioni, John C., Meyer, Kerstin B. and Rawlins, Emma L. (2022). A human fetal lung cell atlas uncovers proximal-distal gradients of differentiation and key regulators of epithelial fates. Cell, 185 (25), 4841-4860.e25. doi: 10.1016/j.cell.2022.11.005 |
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2022 Journal Article Distinct pathogenic roles for resident and monocyte-derived macrophages in lupus nephritisRichoz, Nathan, Tuong, Zewen K., Loudon, Kevin W., Patiño-Martínez, Eduardo, Ferdinand, John R., Portet, Anaïs, Bashant, Kathleen R., Thevenon, Emeline, Rucci, Francesca, Hoyler, Thomas, Junt, Tobias, Kaplan, Mariana J., Siegel, Richard M. and Clatworthy, Menna R. (2022). Distinct pathogenic roles for resident and monocyte-derived macrophages in lupus nephritis. JCI Insight, 7 (21) e159751, 1-19. doi: 10.1172/jci.insight.159751 |
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2022 Journal Article Obesity is associated with attenuated tissue immunity in COVID-19Guo, Shuang A., Bowyer, Georgina S., Ferdinand, John R., Maes, Mailis, Tuong, Zewen K., Gillman, Eleanor, Liao, Mingfeng, Lindeboom, Rik G H, Yoshida, Masahiro, Worlock, Kaylee, Gopee, Hudaa, Stephenson, Emily, Gao, Catherine A, Lyons, Paul A, Smith, Kenneth G C, Haniffa, Muzlifah, Meyer, Kerstin B, Nikolić, Marko Z, Zhang, Zheng, Wunderink, Richard G, Misharin, Alexander V, Dougan, Gordon, Navapurkar, Vilas, Teichmann, Sarah A, Conway Morris, Andrew and Clatworthy, Menna R (2022). Obesity is associated with attenuated tissue immunity in COVID-19. American Journal of Respiratory and Critical Care Medicine, 207 (5), 566-576. doi: 10.1164/rccm.202204-0751OC |
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2022 Journal Article Fracture hematoma micro-architecture influences transcriptional profile and plays a crucial role in determining bone healing outcomesWoloszyk, Anna, Tuong, Zewen K., Perez, Louis, Aguilar, Leonardo, Bankole, Abraham I., Evans, Christopher H. and Glatt, Vaida (2022). Fracture hematoma micro-architecture influences transcriptional profile and plays a crucial role in determining bone healing outcomes. Biomaterials Advances, 139 213027, 1-15. doi: 10.1016/j.bioadv.2022.213027 |
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2022 Journal Article A robust experimental and computational analysis framework at multiple resolutions, modalities and coveragesTran, M., Yoon, S., Teoh, M., Andersen, S., Lam, PY., Purdue, B. W., Raghubar, A., Hanson, S.J., Devitt, K., Jones, K., Walters, S., Monkman, J., Kulasinghe, A., Tuong, Z.K., Soyer, H.P., Frazer, I. H. and Nguyen, Q. (2022). A robust experimental and computational analysis framework at multiple resolutions, modalities and coverages. Frontiers in Immunology, 13 911873, 911873. doi: 10.3389/fimmu.2022.911873 |
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2022 Journal Article Group 3 innate lymphocytes make a distinct contribution to type 17 immunity in bladder defenceRiding, Alexandra M., Loudon, Kevin W., Guo, Andrew, Ferdinand, John R., Lok, Laurence S.C., Richoz, Nathan, Stewart, Andrew, Castro-Dopico, Tomas, Tuong, Zewen Kelvin, Fiancette, Remi, Bowyer, Georgina S., Fleming, Aaron, Gillman, Eleanor S., Suchanek, Ondrej, Mahbubani, Krishnaa T., Saeb-Parsy, Kourosh, Withers, David, Dougan, Gordan, Clare, Simon and Clatworthy, Menna R. (2022). Group 3 innate lymphocytes make a distinct contribution to type 17 immunity in bladder defence. iScience, 25 (7) 104660, 1-30. doi: 10.1016/j.isci.2022.104660 |
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2022 Journal Article Mapping the developing human immune system across organsSuo, Chenqu, Dann, Emma, Goh, Issac, Jardine, Laura, Kleshchevnikov, Vitalii, Park, Jong-Eun, Botting, Rachel A., Stephenson, Emily, Engelbert, Justin, Tuong, Zewen Kelvin, Polanski, Krzysztof, Yayon, Nadav, Xu, Chuan, Suchanek, Ondrej, Elmentaite, Rasa, Domínguez Conde, Cecilia, He, Peng, Pritchard, Sophie, Miah, Mohi, Moldovan, Corina, Steemers, Alexander S., Mazin, Pavel, Prete, Martin, Horsfall, Dave, Marioni, John C., Clatworthy, Menna R., Haniffa, Muzlifah and Teichmann, Sarah A. (2022). Mapping the developing human immune system across organs. Science, 376 (6597) eabo0510, eabo0510-+. doi: 10.1126/science.abo0510 |
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2022 Journal Article Cross-tissue immune cell analysis reveals tissue-specific features in humansDomínguez Conde, C., Xu, C., Jarvis, L. B., Rainbow, D. B., Wells, S. B., Gomes, T., Howlett, S. K., Suchanek, O., Polanski, K., King, H. W., Mamanova, L., Huang, N., Szabo, P. A., Richardson, L., Bolt, L., Fasouli, E. S., Mahbubani, K. T., Prete, M., Tuck, L., Richoz, N., Tuong, Z. K., Campos, L., Mousa, H. S., Needham, E. J., Pritchard, S., Li, T., Elmentaite, R., Park, J., Rahmani, E. ... Teichmann, S. A. (2022). Cross-tissue immune cell analysis reveals tissue-specific features in humans. Science, 376 (6594) eabl5197, eabl5197-+. doi: 10.1126/science.abl5197 |
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2022 Journal Article GIMAP6 regulates autophagy, immune competence, and inflammation in mice and humansYao, Yikun, Du Jiang, Ping, Chao, Brittany N., Cagdas, Deniz, Kubo, Satoshi, Balasubramaniyam, Arasu, Zhang, Yu, Shadur, Bella, NaserEddin, Adeeb, Folio, Les R., Schwarz, Benjamin, Bohrnsen, Eric, Zheng, Lixin, Lynberg, Matthew, Gottlieb, Simone, Leney-Greene, Michael A., Park, Ann Y., Tezcan, Ilhan, Akdogan, Ali, Gocmen, Rahsan, Onder, Sevgen, Rosenberg, Avi, Soilleux, Elizabeth J., Johnson, Errin, Jackson, Peter K., Demeter, Janos, Chauvin, Samuel D., Paul, Florian, Selbach, Matthias ... Lenardo, Michael J. (2022). GIMAP6 regulates autophagy, immune competence, and inflammation in mice and humans. Journal of Experimental Medicine, 219 (6) e20201405, 1-29. doi: 10.1084/jem.20201405 |
