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2019

Journal Article

Single-cell RNA sequencing reveals cell type-specific HPV expression in hyperplastic skin lesions

Devitt, Katharina, Hanson, Sarah J., Tuong, Zewen K., McMeniman, Erin, Soyer, H. Peter, Frazer, Ian H. and Lukowski, Samuel W. (2019). Single-cell RNA sequencing reveals cell type-specific HPV expression in hyperplastic skin lesions. Virology, 537, 14-19. doi: 10.1016/j.virol.2019.08.007

Single-cell RNA sequencing reveals cell type-specific HPV expression in hyperplastic skin lesions

2019

Journal Article

Microprojection arrays applied to skin generate mechanical stress, induce an inflammatory transcriptome and cell death, and improve vaccine-induced immune responses

Ng, Hwee-Ing, Tuong, Zewen K., Fernando, Germain J. P., Depelsenaire, Alexandra C. I., Meliga, Stefano C., Frazer, Ian H. and Kendall, Mark A. F. (2019). Microprojection arrays applied to skin generate mechanical stress, induce an inflammatory transcriptome and cell death, and improve vaccine-induced immune responses. npj Vaccines, 4 (1) 41, 41. doi: 10.1038/s41541-019-0134-4

Microprojection arrays applied to skin generate mechanical stress, induce an inflammatory transcriptome and cell death, and improve vaccine-induced immune responses

2019

Journal Article

Papillomavirus immune evasion strategies target the infected cell and the local immune system

Zhou, Chenhao, Tuong, Zewen Kelvin and Frazer, Ian Hector (2019). Papillomavirus immune evasion strategies target the infected cell and the local immune system. Frontiers in Oncology, 9 682, 682. doi: 10.3389/fonc.2019.00682

Papillomavirus immune evasion strategies target the infected cell and the local immune system

2019

Journal Article

Mechanism of iron oxide-induced macrophage activation: the impact of composition and the underlying signaling pathway

Gu, Zhengying, Liu, Tianqing, Tang, Jie, Yang, Yannan, Song, Hao, Tuong, Zewen K., Fu, Jianye and Yu, Chengzhong (2019). Mechanism of iron oxide-induced macrophage activation: the impact of composition and the underlying signaling pathway. Journal of the American Chemical Society, 141 (15) jacs.8b10904, 6122-6126. doi: 10.1021/jacs.8b10904

Mechanism of iron oxide-induced macrophage activation: the impact of composition and the underlying signaling pathway

2018

Journal Article

Recruitment of antigen presenting cells to skin draining lymph node from HPV16E7-expressing skin requires E7-Rb interaction

Kuo, Paula, Teoh, Siok Min, Tuong, Zewen K., Leggatt, Graham R., Mattarollo, Stephen R. and Frazer, Ian H. (2018). Recruitment of antigen presenting cells to skin draining lymph node from HPV16E7-expressing skin requires E7-Rb interaction. Frontiers in Immunology, 9 2896, 2896. doi: 10.3389/fimmu.2018.02896

Recruitment of antigen presenting cells to skin draining lymph node from HPV16E7-expressing skin requires E7-Rb interaction

2018

Journal Article

Examining the contribution of smoking and HPV towards the etiology of oral cavity squamous cell carcinoma using high-throughput sequencing: a prospective observational study

Zammit, Andrew P., Sinha, Rohit, Cooper, Caroline L., Perry, Christopher F. L., Frazer, Ian H. and Tuong, Zewen K. (2018). Examining the contribution of smoking and HPV towards the etiology of oral cavity squamous cell carcinoma using high-throughput sequencing: a prospective observational study. PLoS One, 13 (10) e0205406, e0205406. doi: 10.1371/journal.pone.0205406

Examining the contribution of smoking and HPV towards the etiology of oral cavity squamous cell carcinoma using high-throughput sequencing: a prospective observational study

2018

Journal Article

Detection of HPV E7 transcription at single-cell resolution in epidermis

Lukowski, S. W., Tuong, Z. K., Noske, K., Senabouth, A., Nguyen, Q. H., Andersen, S. B., Soyer, H. P., Frazer, I. H. and Powell, J. E. (2018). Detection of HPV E7 transcription at single-cell resolution in epidermis. The Journal of Investigative Dermatology, 138 (12), 2558-2567. doi: 10.1016/j.jid.2018.06.169

Detection of HPV E7 transcription at single-cell resolution in epidermis

2018

Journal Article

HPV16E7 Induced Hyperplasia Promotes CXCL9/10 Expression and Induces CXCR3+ T cell Migration to Skin

Kuo, Paula, Tuong, Zewen K, Teoh, Siok Min, Frazer, Ian H, Mattarollo, Stephen and Leggatt, Graham R (2018). HPV16E7 Induced Hyperplasia Promotes CXCL9/10 Expression and Induces CXCR3+ T cell Migration to Skin. The Journal of investigative dermatology, 138 (6), 1348-1359. doi: 10.1016/j.jid.2017.12.021

HPV16E7 Induced Hyperplasia Promotes CXCL9/10 Expression and Induces CXCR3+ T cell Migration to Skin

2018

Journal Article

Characterization of 7A7, an anti-mouse EGFR monoclonal antibody proposed to be the mouse equivalent of cetuximab

He, Xuzhi, Cruz, Jazmina L., Joseph, Shannon, Pett, Nicola, Chew, Hui Yi, Tuong, Zewen K., Okano, Satomi, Kelly, Gabrielle, Veitch, Margaret, Simpson, Fiona and Wells, James W. (2018). Characterization of 7A7, an anti-mouse EGFR monoclonal antibody proposed to be the mouse equivalent of cetuximab. Oncotarget, 9 (15), 12250-12260. doi: 10.18632/oncotarget.24242

Characterization of 7A7, an anti-mouse EGFR monoclonal antibody proposed to be the mouse equivalent of cetuximab

2018

Journal Article

B cell lymphoma progression promotes the accumulation of circulating Ly6Clo monocytes with immunosuppressive activity

McKee, Sara J., Tuong, Zewen K., Kobayashi, Takumi, Doff, Brianna L., Soon, Megan S. F ., Nissen, Michael, Lam, Pui Yeng, Keane, Colm, Vari, Frank, Moi, Davide, Mazzieri, Roberta, Leggatt, Graham, Gandhi, Maher K. and Mattarollo, Stephen R. (2018). B cell lymphoma progression promotes the accumulation of circulating Ly6Clo monocytes with immunosuppressive activity. OncoImmunology, 7 (2) e1393599, e1393599. doi: 10.1080/2162402X.2017.1393599

B cell lymphoma progression promotes the accumulation of circulating Ly6Clo monocytes with immunosuppressive activity

2017

Journal Article

Modulation of antigen presenting cell functions during chronic HPV infection

Bashaw, Abate Assefa, Leggatt, Graham R., Chandra, Janin, Tuong, Zewen K. and Frazer, Ian H. (2017). Modulation of antigen presenting cell functions during chronic HPV infection. Papillomavirus Research, 4, 58-65. doi: 10.1016/j.pvr.2017.08.002

Modulation of antigen presenting cell functions during chronic HPV infection

2017

Journal Article

Murine HPV16 E7-expressing transgenic skin effectively emulates the cellular and molecular features of human high-grade squamous intraepithelial lesions

Tuong, Z. K., Noske, K., Kuo, P., Bashaw, A. A., Teoh, S. M. and Frazer, I. H. (2017). Murine HPV16 E7-expressing transgenic skin effectively emulates the cellular and molecular features of human high-grade squamous intraepithelial lesions. Papillomavirus Research, 5, 6-20. doi: 10.1016/j.pvr.2017.10.001

Murine HPV16 E7-expressing transgenic skin effectively emulates the cellular and molecular features of human high-grade squamous intraepithelial lesions

2016

Journal Article

Transgenic adipose-specific expression of the nuclear receptor RORα drives a striking shift in fat distribution and impairs glycemic control

Tuong, Zewen Kelvin, Fitzsimmons, Rebecca, Wang, Shu-Ching Mary, Oh, Tae Gyu, Lau, Patrick, Steyn, Frederik, Thomas, Gethin and Muscat, George E. O. (2016). Transgenic adipose-specific expression of the nuclear receptor RORα drives a striking shift in fat distribution and impairs glycemic control. EBioMedicine, 11, 101-117. doi: 10.1016/j.ebiom.2016.08.027

Transgenic adipose-specific expression of the nuclear receptor RORα drives a striking shift in fat distribution and impairs glycemic control

2016

Journal Article

A mouse model of hyperproliferative human epithelium validated by keratin profiling ahows an aberrant cytoskeletal response to injury

Zhussupbekova, Samal, Sinha, Rohit, Kuo, Paula, Lambert, Paul F., Frazer, Ian H. and Tuong, Zewen K. (2016). A mouse model of hyperproliferative human epithelium validated by keratin profiling ahows an aberrant cytoskeletal response to injury. Ebiomedicine, 9, 314-323. doi: 10.1016/j.ebiom.2016.06.011

A mouse model of hyperproliferative human epithelium validated by keratin profiling ahows an aberrant cytoskeletal response to injury

2016

Journal Article

The nuclear receptor, Nor-1, induces the physiological responses associated with excercise

Goode, Joel M., Pearen, Michael A., Tuong, Zewen K., Wang, Shu-Ching M., Oh, Tae Gyu, Shao, Emily X. and Muscat, George E. (2016). The nuclear receptor, Nor-1, induces the physiological responses associated with excercise. Molecular Endocrinology, 30 (6), 660-676. doi: 10.1210/me.2015-1300

The nuclear receptor, Nor-1, induces the physiological responses associated with excercise

2016

Other Outputs

Retinoid-related orphan nuclear receptor alpha and macrophages in lipid metabolism and immunity

Tuong, Zewen Kelvin (2016). Retinoid-related orphan nuclear receptor alpha and macrophages in lipid metabolism and immunity. PhD Thesis, Institute for Molecular Bioscience, The University of Queensland. doi: 10.14264/uql.2016.950

Retinoid-related orphan nuclear receptor alpha and macrophages in lipid metabolism and immunity

2016

Journal Article

RORα and 25-hydroxycholesterol crosstalk regulates lipid droplet homeostasis in macrophages

Tuong, Zewen Kelvin, Lau, Patrick, Du, Ximing, Condon, Nicholas D., Goode, Joel M., Oh, Tae Gyu, Yeo, Jeremy C., Muscat, George E. O. and Stow, Jennifer L. (2016). RORα and 25-hydroxycholesterol crosstalk regulates lipid droplet homeostasis in macrophages. PLoS ONE, 11 (1) e0147179, e0147179. doi: 10.1371/journal.pone.0147179

RORα and 25-hydroxycholesterol crosstalk regulates lipid droplet homeostasis in macrophages

2016

Conference Publication

Pre-malignant immune suppressive environment is dependent on HPV16E7-Rb interaction induced epithelium hyperplasia

Kuo, P., Tuong, K., Mattarollo, S. and Frazer, I. (2016). Pre-malignant immune suppressive environment is dependent on HPV16E7-Rb interaction induced epithelium hyperplasia. International Congress of Immunology (ICI), Melbourne, VIC, Australia, 21-26 August 2016. Weinheim, Germany: Wiley - VCH. doi: 10.1002/eji.201670200

Pre-malignant immune suppressive environment is dependent on HPV16E7-Rb interaction induced epithelium hyperplasia

2016

Conference Publication

Immunotherapy for persisting viral infection and associated cancer

Frazer, I, Mattarollo, S., Leggatt, G., Wells, J., Tuong, K., Kuo, P., Jazayeri, S., Lambert, P. and Chandra, J. (2016). Immunotherapy for persisting viral infection and associated cancer. ICI 2016 International Congress of Immunology, Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley.

Immunotherapy for persisting viral infection and associated cancer

2016

Conference Publication

Exhausted T cell signature enriched in HPV16 E7 mouse model and cervical intraepithelial neoplasia grade III

Tuong, Z. K. , Kuo, P. , Sinha, R. , Tolley, L. and Frazer, I. H. (2016). Exhausted T cell signature enriched in HPV16 E7 mouse model and cervical intraepithelial neoplasia grade III. ICI 2016 International Congress of Immunology, Melbourne, VIC, Australia, 21-26 August 2016. Weinheim, Germany: Wiley-VCH. doi: 10.1002/eji.201670200

Exhausted T cell signature enriched in HPV16 E7 mouse model and cervical intraepithelial neoplasia grade III