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2017

Journal Article

The Use of Plasmapheresis in Patients with Bronchiectasis with Pseudomonas aeruginosa Infection and Inhibitory Antibodies

Wells, Timothy J., Davison, John, Sheehan, Emma, Kanagasundaram, Suren, Spickett, Gavin, MacLennan, Calman A., Stockley, Robert A., Cunningham, Adam F., Henderson, Ian R. and De Soyza, Anthony (2017). The Use of Plasmapheresis in Patients with Bronchiectasis with Pseudomonas aeruginosa Infection and Inhibitory Antibodies. American Journal of Respiratory and Critical Care Medicine, 195 (7), 955-958. doi: 10.1164/rccm.201603-0599LE

The Use of Plasmapheresis in Patients with Bronchiectasis with Pseudomonas aeruginosa Infection and Inhibitory Antibodies

2026

Journal Article

Treatment of <i>Pseudomonas</i> by removal of cloaking antibodies; is common polysaccharide antigen a factor?

Monteith, Joshua N, Ledger, Emma L, Chamoun, Michelle N, Henderson, Ian R, Goldberg, Joanna B, Smith, Daniel, Chambers, Daniel C, Apte, Simon H and Wells, Timothy J (2026). Treatment of Pseudomonas by removal of cloaking antibodies; is common polysaccharide antigen a factor?. The Journal of Infectious Diseases, 233 (4) jiag002, e948-e956. doi: 10.1093/infdis/jiag002

Treatment of <i>Pseudomonas</i> by removal of cloaking antibodies; is common polysaccharide antigen a factor?

2025

Conference Publication

Cloaking antibodies prevent immune detection and destruction of inflammatory Crohn’s microbiota, resulting in treatment resistance: the first description of a central pathogenic mechanism

Feng, Wenkang, Tovey-Matthews, Abigail, Schulberg, Julien D., Hamilton, Amy L., Lovett, Grace C., Wright, Emily K., Kamm, Michael A., Morrison, Mark and Wells, Timothy (2025). Cloaking antibodies prevent immune detection and destruction of inflammatory Crohn’s microbiota, resulting in treatment resistance: the first description of a central pathogenic mechanism. Digestive Disease Week (DDW) 2025, San Diego, CA United States, 3-6 August 2025. Philadelphia, PA United States: Elsevier. doi: 10.1016/s0016-5085(25)02172-9

Cloaking antibodies prevent immune detection and destruction of inflammatory Crohn’s microbiota, resulting in treatment resistance: the first description of a central pathogenic mechanism

2025

Journal Article

Ceftriaxone-loaded liposomal nanoparticles for pulmonary delivery against lower respiratory tract infections: development and characterization

Panthi, Vijay Kumar, Fairfull-Smith, Kathryn E., Wells, Timothy J., Wang, Tony and Islam, Nazrul (2025). Ceftriaxone-loaded liposomal nanoparticles for pulmonary delivery against lower respiratory tract infections: development and characterization. Pharmaceuticals, 18 (3) 414. doi: 10.3390/ph18030414

Ceftriaxone-loaded liposomal nanoparticles for pulmonary delivery against lower respiratory tract infections: development and characterization

2025

Journal Article

Emerging antimicrobial therapies for Gram-negative infections in human clinical use

Hickson, Sarah M., Ledger, Emma L. and Wells, Timothy J. (2025). Emerging antimicrobial therapies for Gram-negative infections in human clinical use. npj Antimicrobials and Resistance, 3 (1) 16, 1-15. doi: 10.1038/s44259-025-00087-2

Emerging antimicrobial therapies for Gram-negative infections in human clinical use

2025

Journal Article

Inhaled combined antibacterials against biofilm-forming antibiotic-resistant bacteria for the management of pulmonary bacterial infections

Suraweera, Ruwani K., Spann, Kirsten M., Wells, Timothy J. and Islam, Nazrul (2025). Inhaled combined antibacterials against biofilm-forming antibiotic-resistant bacteria for the management of pulmonary bacterial infections. Journal of Drug Delivery Science and Technology, 104 106555, 106555. doi: 10.1016/j.jddst.2024.106555

Inhaled combined antibacterials against biofilm-forming antibiotic-resistant bacteria for the management of pulmonary bacterial infections

2025

Journal Article

Understanding the pathophysiology of Pseudomonas aeruginosa colonization as a guide for future treatment for chronic leg ulcers

Matheus, Gabriela Gonzalez, Chamoun, Michelle N., Khosrotehrani, Kiarash, Sivakumaran, Yogeesan and Wells, Timothy J. (2025). Understanding the pathophysiology of Pseudomonas aeruginosa colonization as a guide for future treatment for chronic leg ulcers. Burns and Trauma, 13 tkae083, tkae083. doi: 10.1093/burnst/tkae083

Understanding the pathophysiology of Pseudomonas aeruginosa colonization as a guide for future treatment for chronic leg ulcers

2024

Journal Article

Development and characterization of spray-dried combined levofloxacin–ambroxol dry powder inhaler formulation

Suraweera, Ruwani K., Spann, Kirsten M., Izake, Emad L., Wells, Timothy J., Wang, Xiaodong and Islam, Nazrul (2024). Development and characterization of spray-dried combined levofloxacin–ambroxol dry powder inhaler formulation. Pharmaceutics, 16 (12) 1506, 1506. doi: 10.3390/pharmaceutics16121506

Development and characterization of spray-dried combined levofloxacin–ambroxol dry powder inhaler formulation

2024

Journal Article

Dichotomous outcomes of TNFR1 and TNFR2 signaling in NK cell-mediated immune responses during inflammation

McCulloch, Timothy R., Rossi, Gustavo R., Alim, Louisa, Lam, Pui Yeng, Wong, Joshua K. M., Coleborn, Elaina, Kumari, Snehlata, Keane, Colm, Kueh, Andrew J., Herold, Marco J., Wilhelm, Christoph, Knolle, Percy A., Kane, Lawrence, Wells, Timothy J. and Souza-Fonseca-Guimaraes, Fernando (2024). Dichotomous outcomes of TNFR1 and TNFR2 signaling in NK cell-mediated immune responses during inflammation. Nature Communications, 15 (1) 9871, 1-16. doi: 10.1038/s41467-024-54232-y

Dichotomous outcomes of TNFR1 and TNFR2 signaling in NK cell-mediated immune responses during inflammation

2024

Journal Article

Type 5 secretion system antigens as vaccines against Gram-negative bacterial infections

Da Costa, Rochelle M., Rooke, Jessica L., Wells, Timothy J., Cunningham, Adam F. and Henderson, Ian R. (2024). Type 5 secretion system antigens as vaccines against Gram-negative bacterial infections. npj Vaccines, 9 (1) 159, 159. doi: 10.1038/s41541-024-00953-6

Type 5 secretion system antigens as vaccines against Gram-negative bacterial infections

2024

Journal Article

Cloaking antibodies are prevalent in Burkholderia cepacia complex infection and their removal restores serum killing

Pham, Amy, Tan, Kellynn K. Y., Ledger, Emma L., Smith, Daniel J., Reid, David W., Burr, Lucy, Chambers, Daniel C. and Wells, Timothy J. (2024). Cloaking antibodies are prevalent in Burkholderia cepacia complex infection and their removal restores serum killing. Frontiers in Cellular and Infection Microbiology, 14 1426773, 1426773. doi: 10.3389/fcimb.2024.1426773

Cloaking antibodies are prevalent in Burkholderia cepacia complex infection and their removal restores serum killing

2024

Journal Article

Mechanisms of antibody-dependent enhancement of infectious disease

Wells, Timothy J., Esposito, Tyron, Henderson, Ian R. and Labzin, Larisa I. (2024). Mechanisms of antibody-dependent enhancement of infectious disease. Nature Reviews Immunology, 25 (1) e33073, 6-21. doi: 10.1038/s41577-024-01067-9

Mechanisms of antibody-dependent enhancement of infectious disease

2024

Conference Publication

Does a leopard change its spots? Pseudomonas aeruginosa in cystic fibrosis after CFTR modulation

Ledger, Emma, Smith, Daniel, Teh, Jing Jie, Wood, Michelle, Whibley, Page, Morrison, Mark, Goldberg, Joanna, Reid, David and Wells, Timothy (2024). Does a leopard change its spots? Pseudomonas aeruginosa in cystic fibrosis after CFTR modulation. Abstracts of the 15th Australasian Cystic Fibrosis Conference, Brisbane, QLD, Australia, 2–4 August 2024. Richmond, VIC, Australia: John Wiley & Sons.

Does a leopard change its spots? Pseudomonas aeruginosa in cystic fibrosis after CFTR modulation

2024

Journal Article

The immune checkpoint TIGIT is upregulated on T cells during bacterial infection and is a potential target for immunotherapy

McCulloch, Timothy R., Rossi, Gustavo R., Miranda‐Hernandez, Socorro, Valencia‐Hernandez, Ana Maria, Alim, Louisa, Belle, Clemence J., Krause, Andrew, Zacchi, Lucia F., Lam, Pui Yeng, Nakamura, Kyohei, Kupz, Andreas, Wells, Timothy J. and Souza‐Fonseca‐Guimaraes, Fernando (2024). The immune checkpoint TIGIT is upregulated on T cells during bacterial infection and is a potential target for immunotherapy. Immunology and Cell Biology, 102 (8), 721-733. doi: 10.1111/imcb.12794

The immune checkpoint TIGIT is upregulated on T cells during bacterial infection and is a potential target for immunotherapy

2024

Journal Article

Impact of CFTR modulation on Pseudomonas aeruginosa infection in people with cystic fibrosis

Ledger, Emma L., Smith, Daniel J., Teh, Jing Jie, Wood, Michelle E., Whibley, Page E., Morrison, Mark, Goldberg, Joanna B., Reid, David W. and Wells, Timothy J. (2024). Impact of CFTR modulation on Pseudomonas aeruginosa infection in people with cystic fibrosis. The Journal of Infectious Diseases, 230 (3), e536-e547. doi: 10.1093/infdis/jiae051

Impact of CFTR modulation on Pseudomonas aeruginosa infection in people with cystic fibrosis

2024

Journal Article

Antibody-mediated serum resistance protects Pseudomonas aeruginosa during bloodstream infections

Hickson, Sarah M., Hoehensteiger, Johannes K., Mayer-Coverdale, Johanna, Torres, Von Vergel L., Feng, Wenkang, Monteith, Joshua N., Henderson, Ian R., McCarthy, Kate L. and Wells, Timothy J. (2024). Antibody-mediated serum resistance protects Pseudomonas aeruginosa during bloodstream infections. The Journal of Infectious Diseases, 230 (2), e221-e229. doi: 10.1093/infdis/jiad457

Antibody-mediated serum resistance protects Pseudomonas aeruginosa during bloodstream infections

2023

Journal Article

Genomic analyses of Burkholderia respiratory isolates indicates two evolutionarily distinct B. anthina clades

Pham, Amy, Volmer, James G., Chambers, Daniel C., Smith, Daniel J., Reid, David W., Burr, Lucy and Wells, Timothy J. (2023). Genomic analyses of Burkholderia respiratory isolates indicates two evolutionarily distinct B. anthina clades. Frontiers in Microbiology, 14 1274280, 1-14. doi: 10.3389/fmicb.2023.1274280

Genomic analyses of Burkholderia respiratory isolates indicates two evolutionarily distinct B. anthina clades

2023

Conference Publication

Goblet cell specific anti-apoptotic role of interleukin-24 in spondyloarthritis-associated ileitis

Cameron, Amy, Giri, Rabina, Begun, Jakob, Wells, Timothy, Thomas, Ranjeny and Bergot, Anne-Sophie (2023). Goblet cell specific anti-apoptotic role of interleukin-24 in spondyloarthritis-associated ileitis. ACR Convergence 2023, San Diego, CA, United States, 10 - 15 November 2023. Hoboken, NJ, United States: John Wiley & Sons.

Goblet cell specific anti-apoptotic role of interleukin-24 in spondyloarthritis-associated ileitis

2023

Journal Article

Leveraging the COVID-19 pandemic as a natural experiment to assess changes in antibiotic use and antibiotic-resistant E. coli carriage in semi-rural Ecuador

Amato, Heather K., Loayza, Fernanda, Salinas, Liseth, Paredes, Diana, Garcia, Daniela, Sarzosa, Soledad, Saraiva-Garcia, Carlos, Johnson, Timothy J., Pickering, Amy J., Riley, Lee W., Trueba, Gabriel and Graham, Jay P. (2023). Leveraging the COVID-19 pandemic as a natural experiment to assess changes in antibiotic use and antibiotic-resistant E. coli carriage in semi-rural Ecuador. Scientific Reports, 13 (1) 14854. doi: 10.1038/s41598-023-39532-5

Leveraging the COVID-19 pandemic as a natural experiment to assess changes in antibiotic use and antibiotic-resistant E. coli carriage in semi-rural Ecuador

2023

Conference Publication

Goblet cell specific anti-apoptotic role of interleukin-24 in spondyloarthritis-associated ileitis

Cameron, A., Giri, R., Begun, J., Wells, T., Bergot, A. S. and Thomas, R. (2023). Goblet cell specific anti-apoptotic role of interleukin-24 in spondyloarthritis-associated ileitis. EULAR 2023 European Congress of Rheumatology, Milan, Italy, 31 May-3 June 2023. London, United Kingdom: BMJ Group. doi: 10.1136/annrheumdis-2023-eular.1346

Goblet cell specific anti-apoptotic role of interleukin-24 in spondyloarthritis-associated ileitis