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2021 Journal Article Impact of the epithelial lining fluid milieu on amikacin pharmacodynamics against Pseudomonas aeruginosaHeffernan, Aaron J., Sime, Fekade B., Lim, Sazlyna Mohd Sazlly, Naicker, Saiyuri, Andrews, Katherine T., Ellwood, David, Lipman, Jeffrey, Grimwood, Keith and Roberts, Jason A. (2021). Impact of the epithelial lining fluid milieu on amikacin pharmacodynamics against Pseudomonas aeruginosa. Drugs in R&D, 21 (2), 203-215. doi: 10.1007/s40268-021-00344-5 |
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2021 Journal Article Standard of practice in intensive care for pharmacy servicesJohnston, Karlee, Ankravs, Melissa J., Badman, Belinda, Choo, Chui Lynn, Cree, Michele, Fyfe, Rachel, Roberts, Jason A., Xu, Jessica and Munro, Courtney (2021). Standard of practice in intensive care for pharmacy services. Journal of Pharmacy Practice and Research, 51 (2), 165-183. doi: 10.1002/jppr.1718 |
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2021 Journal Article Antimicrobial dosing in prolonged intermittent renal replacement therapy: a systematic reviewRawlins, Matthew D. M., Misko, Jeanie and Roberts, Jason A. (2021). Antimicrobial dosing in prolonged intermittent renal replacement therapy: a systematic review. Journal of Pharmacy Practice and Research, 51 (2), 106-120. doi: 10.1002/jppr.1723 |
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2021 Journal Article Model-informed drug development for anti-infectives: state of the art and futureRayner, Craig R., Smith, Patrick F., Andes, David, Andrews, Kayla, Derendorf, Hartmut, Friberg, Lena E., Hanna, Debra, Lepak, Alex, Mills, Edward, Polasek, Thomas M., Roberts, Jason A., Schuck, Virna, Shelton, Mark J., Wesche, David and Rowland-Yeo, Karen (2021). Model-informed drug development for anti-infectives: state of the art and future. Clinical Pharmacology and Therapeutics, 109 (4), 867-891. doi: 10.1002/cpt.2198 |
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2021 Journal Article Evaluation of meropenem-ciprofloxacin combination dosage regimens for the pharmacokinetics of critically ill patients with augmented renal clearanceAgyeman, Akosua A., Rogers, Kate E., Tait, Jessica R., Bergen, Phillip J., Kirkpatrick, Carl M., Wallis, Steven C., Bulitta, Jürgen B., Paterson, David L., Lipman, Jeffrey, Nation, Roger L., Roberts, Jason A. and Landersdorfer, Cornelia B. (2021). Evaluation of meropenem-ciprofloxacin combination dosage regimens for the pharmacokinetics of critically ill patients with augmented renal clearance. Clinical Pharmacology and Therapeutics, 109 (4), 1104-1115. doi: 10.1002/cpt.2191 |
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2021 Journal Article Provider perspectives on beta-lactam therapeutic drug monitoring programs in the critically ill: a protocol for a multicenter mixed-methods studyBarreto, Erin F., Rule, Andrew D., Alshaer, Mohammad H., Roberts, Jason A., Abdul Aziz, Mohd Hafiz, Scheetz, Marc H., Mara, Kristin C., Jannetto, Paul J., Gajic, Ognjen, O'Horo, John C and Boehmer, Kasey R (2021). Provider perspectives on beta-lactam therapeutic drug monitoring programs in the critically ill: a protocol for a multicenter mixed-methods study. Implementation science communications, 2 (1) 34, 34-1. doi: 10.1186/s43058-021-00134-9 |
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2021 Journal Article PLGA encapsulated γ-cyclodextrin-meropenem inclusion complex formulation for oral deliveryRaza, Aun, Miles, Jared A., Bruck Sime, Fekade, Ross, Benjamin P., Roberts, Jason A., Popat, Amirali, Kumeria, Tushar and Falconer, James R. (2021). PLGA encapsulated γ-cyclodextrin-meropenem inclusion complex formulation for oral delivery. International Journal of Pharmaceutics, 597 120280, 120280. doi: 10.1016/j.ijpharm.2021.120280 |
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2021 Journal Article Protocol for an international, multicentre, prospective, observational study of nosocomial pneumonia in intensive care units: The PneumoINSPIRE studyKoulenti, Despoina, Armaganidis, Apostolos, Arvaniti, Kostoula, Blot, Stijn, Brun-Buisson, Christian, Deja, Maria, De Waele, Jan, Du, Bin, Dulhunty, Joel M., Garcia-Diaz, Julia, Judd, Matthew, Paterson, David L., Putensen, Christian, Reina, Rosa, Rello, Jordi, Restrepo, Marcos I., Roberts, Jason A., Sjovall, Fredrik, Timsit, Jean-Francois, Tsiodras, Sotirios, Zahar, Jean-Ralph, Zhang, Yuchi, Lipman, Jeffrey and On behalf of the Working Group on Pneumonia of the European Society of Intensive Care Medicine (2021). Protocol for an international, multicentre, prospective, observational study of nosocomial pneumonia in intensive care units: The PneumoINSPIRE study. Critical Care and Resuscitation, 23 (1), 59-66. doi: 10.51893/2021.1.oa5 |
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2021 Journal Article Pharmacodynamics of once- versus twice-daily dosing of nebulized amikacin in an in vitro Hollow-Fiber Infection Model against 3 clinical isolates of Pseudomonas aeruginosaHeffernan, Aaron James, Sime, Fekade Bruck, Naicker, Saiyuri, Andrews, Katherine, Ellwood, David, Guerra-Valero, Yarmarly, Wallis, Steven, Lipman, Jeffrey, Grimwood, Keith and Roberts, Jason Alexander (2021). Pharmacodynamics of once- versus twice-daily dosing of nebulized amikacin in an in vitro Hollow-Fiber Infection Model against 3 clinical isolates of Pseudomonas aeruginosa. Diagnostic microbiology and infectious disease, 100 (2) 115329, 115329. doi: 10.1016/j.diagmicrobio.2021.115329 |
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2021 Journal Article Comparative lung distribution of radiolabeled tobramycin between nebulized and intravenous administration in a mechanically-ventilated ovine model, an observational studyDhanani, Jayesh A., Goodman, Steven, Ahern, Benjamin, Cohen, Jeremy, Fraser, John F., Barnett, Adrian, Diab, Sara, Bhatt, Manoj and Roberts, Jason A. (2021). Comparative lung distribution of radiolabeled tobramycin between nebulized and intravenous administration in a mechanically-ventilated ovine model, an observational study. International Journal of Antimicrobial Agents, 57 (2) 106232, 106232. doi: 10.1016/j.ijantimicag.2020.106232 |
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2021 Journal Article Population pharmacokinetics analysis of amikacin initial dosing regimen in elderly patientsKato, Hideo, Parker, Suzanne L., Roberts, Jason A., Hagihara, Mao, Asai, Nobuhiro, Yamagishi, Yuka, Paterson, David L. and Mikamo, Hiroshige (2021). Population pharmacokinetics analysis of amikacin initial dosing regimen in elderly patients. Antibiotics, 10 (2) 100, 1-13. doi: 10.3390/antibiotics10020100 |
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2021 Journal Article Population pharmacokinetics of levetiracetam in patients with traumatic brain injury and subarachnoid hemorrhage exhibiting augmented renal clearanceSime, Fekade Bruck, Roberts, Jason A., Jeffree, Rosalind L., Pandey, Saurabh, Adiraju, Santosh, Livermore, Amelia, Butler, Jenie, Parker, Suzanne L., Wallis, Steven C., Lipman, Jeffrey and Cotta, Menino Osbert (2021). Population pharmacokinetics of levetiracetam in patients with traumatic brain injury and subarachnoid hemorrhage exhibiting augmented renal clearance. Clinical Pharmacokinetics, 60 (5), 655-664. doi: 10.1007/s40262-020-00979-8 |
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2021 Journal Article Liquid CO2 formulated mesoporous silica nanoparticles for pH-responsive oral delivery of meropenemRaza, Aun, Sime, Fekade Bruck, Cabot, Peter J., Roberts, Jason A., Falconer, James R., Kumeria, Tushar and Popat, Amirali (2021). Liquid CO2 formulated mesoporous silica nanoparticles for pH-responsive oral delivery of meropenem. ACS Biomaterials Science and Engineering, 7 (5) acsbiomaterials.0c01284, 1836-1853. doi: 10.1021/acsbiomaterials.0c01284 |
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2021 Journal Article Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021Evans, Laura, Rhodes, Andrew, Alhazzani, Waleed, Antonelli, Massimo, Coopersmith, Craig M., French, Craig, Machado, Flávia R., Mcintyre, Lauralyn, Ostermann, Marlies, Prescott, Hallie C., Schorr, Christa, Simpson, Steven, Wiersinga, W. Joost, Alshamsi, Fayez, Angus, Derek C., Arabi, Yaseen, Azevedo, Luciano, Beale, Richard, Beilman, Gregory, Belley-Cote, Emilie, Burry, Lisa, Cecconi, Maurizio, Centofanti, John, Coz Yataco, Angel, De Waele, Jan, Dellinger, R. Phillip, Doi, Kent, Du, Bin, Estenssoro, Elisa ... Levy, Mitchell (2021). Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021. Intensive Care Medicine, 47 (11), 1181-1247. doi: 10.1007/s00134-021-06506-y |
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2021 Journal Article The impact of pharmacist-led antifungal stewardship interventions in the hospital setting: a systematic reviewKhanina, Anna, Cairns, Kelly A., Kong, David C. M., Thursky, Karin A., Slavin, Monica A. and Roberts, Jason A. (2021). The impact of pharmacist-led antifungal stewardship interventions in the hospital setting: a systematic review. Journal of Pharmacy Practice and Research, 51 (2), 90-105. doi: 10.1002/jppr.1721 |
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2021 Journal Article Antimicrobial pharmacokinetics and preclinical in vitro models to support optimized treatment approaches for uncomplicated lower urinary tract infectionsAbbott, Iain J., Roberts, Jason A., Meletiadis, Joseph and Peleg, Anton Y. (2021). Antimicrobial pharmacokinetics and preclinical in vitro models to support optimized treatment approaches for uncomplicated lower urinary tract infections. Expert Review of Anti-infective Therapy, 19 (3), 271-295. doi: 10.1080/14787210.2020.1813567 |
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2021 Journal Article A meta-analysis of protein binding of flucloxacillin in healthy volunteers and hospitalized patientsWallenburg, Eveline, Brüggemann, Roger J. M., Roberts, Jason A., Jager, Nynke G. L., Ulldemolins, Marta, Wilkes, Sarah, Schouten, Jeroen, Chin, Paul K. L. and ter Heine, Rob (2021). A meta-analysis of protein binding of flucloxacillin in healthy volunteers and hospitalized patients. Clinical Microbiology and Infection, 28 (3), 446.e1-446.e7. doi: 10.1016/j.cmi.2021.06.039 |
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2020 Journal Article Optimization of Ganciclovir use in allogeneic hematopoietic cell transplant recipients – the role of therapeutic drug monitoringHo, Su Ann, Slavin, Monica, Roberts, Jason A. and Yong, Michelle (2020). Optimization of Ganciclovir use in allogeneic hematopoietic cell transplant recipients – the role of therapeutic drug monitoring. Expert Review of Anti-infective Therapy, 19 (6), 1-12. doi: 10.1080/14787210.2021.1851193 |
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2020 Journal Article A systematic review of studies reporting antibiotic pharmacokinetic data in the cerebrospinal fluid of critically Ill patients with uninflamed meningesKumta, Nilesh, Roberts, Jason A., Lipman, Jeffrey, Wong, Wai Tat, Joynt, Gavin M. and Cotta, Menino Osbert (2020). A systematic review of studies reporting antibiotic pharmacokinetic data in the cerebrospinal fluid of critically Ill patients with uninflamed meninges. Antimicrobial Agents and Chemotherapy, 65 (1) e01998-20, 1-19. doi: 10.1128/aac.01998-20 |
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2020 Journal Article Cerebrospinal fluid penetration of ceftolozane/tazobactam in critically ill patients with an indwelling external ventricular drainSime, Fekade B, Lassig-Smith, Melissa, Starr, Therese, Stuart, Janine, Pandey, Saurabh, Parker, Suzanne L., Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2020). Cerebrospinal fluid penetration of ceftolozane/tazobactam in critically ill patients with an indwelling external ventricular drain. Antimicrobial Agents and Chemotherapy, 65 (1) e01698-20, 1-11. doi: 10.1128/aac.01698-20 |
