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2020

Journal Article

A validated LC-MS/MS method for the simultaneous quantification of the novel combination antibiotic, ceftolozane–tazobactam, in plasma (total and unbound), CSF, urine and renal replacement therapy effluent: application to pilot pharmacokinetic studies

Parker, Suzanne L., Pandey, Saurabh, Sime, Fekade B., Stuart, Janine, Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2020). A validated LC-MS/MS method for the simultaneous quantification of the novel combination antibiotic, ceftolozane–tazobactam, in plasma (total and unbound), CSF, urine and renal replacement therapy effluent: application to pilot pharmacokinetic studies. Clinical Chemistry and Laboratory Medicine (CCLM), 59 (5), 921-933. doi: 10.1515/cclm-2020-1196

A validated LC-MS/MS method for the simultaneous quantification of the novel combination antibiotic, ceftolozane–tazobactam, in plasma (total and unbound), CSF, urine and renal replacement therapy effluent: application to pilot pharmacokinetic studies

2020

Journal Article

Australian National Enterovirus Reference Laboratory annual report, 2019

Hobday, Linda K., Ibrahim, Aishah, Kaye, Matthew E., Bruggink, Leesa, Chanthalavanh, Presa, Garcia-Clapes, Arnau, Roberts, Jason A. and Thorley, Bruce R. (2020). Australian National Enterovirus Reference Laboratory annual report, 2019. Communicable diseases intelligence (2018), 44, 1-15. doi: 10.33321/cdi.2020.44.94

Australian National Enterovirus Reference Laboratory annual report, 2019

2020

Journal Article

β-lactam dosing strategies: think before you push

Liu, Jiajun, Rhodes, Nathaniel J., Roberts, Jason A., Pais, Gwendolyn M., Turner, Ben, Kiel, Patrick J. and Scheetz, Marc H. (2020). β-lactam dosing strategies: think before you push. International Journal of Antimicrobial Agents, 56 (5) 106151, 1-4. doi: 10.1016/j.ijantimicag.2020.106151

β-lactam dosing strategies: think before you push

2020

Journal Article

Oral meropenem for superbugs: challenges and opportunities

Raza, Aun, Ngieng, Shih Chen, Sime, Fekade Bruck, Cabot, Peter J., Roberts, Jason A., Popat, Amirali, Kumeria, Tushar and Falconer, James R. (2020). Oral meropenem for superbugs: challenges and opportunities. Drug Discovery Today, 26 (2), 551-560. doi: 10.1016/j.drudis.2020.11.004

Oral meropenem for superbugs: challenges and opportunities

2020

Journal Article

Vancomycin serum concentration after 48 h of administration: A 3-years survey in an intensive care unit

Perin, Nicolas, Roger, Claire, Marin, Grégory, Molinari, Nicolas, Evrard, Alexandre, Lavigne, Jean-Philippe, Barbar, Saber, Claret, Pierre Géraud, Boutin, Caroline, Muller, Laurent, Lipman, Jeffrey, Lefrant, Jean-Yves, Jaber, Samir and Roberts, Jason A. (2020). Vancomycin serum concentration after 48 h of administration: A 3-years survey in an intensive care unit. Antibiotics, 9 (11) 793, 1-16. doi: 10.3390/antibiotics9110793

Vancomycin serum concentration after 48 h of administration: A 3-years survey in an intensive care unit

2020

Journal Article

Prolonged infusion of beta-lactam antibiotics for Gram-negative infections: rationale and evidence base

Abdul-Aziz, Mohd H., Portunato, Federica and Roberts, Jason A. (2020). Prolonged infusion of beta-lactam antibiotics for Gram-negative infections: rationale and evidence base. Current Opinion in Infectious Diseases, 33 (6), 501-510. doi: 10.1097/qco.0000000000000681

Prolonged infusion of beta-lactam antibiotics for Gram-negative infections: rationale and evidence base

2020

Journal Article

Therapeutic drug monitoring of commonly used anti-infective agents: A nationwide cross-sectional survey of Australian hospital practices

Imani, Sahand, Alffenaar, Jan-Willem, Cotta, Menino O., Daveson, Kathryn, van Hal, Sebastiaan, Lau, Cindy, Marriott, Debbie, Penm, Jonathan, Roberts, Jason A., Tabah, Alexis, Trethewy, Nicholas, Williams, Paul and Sandaradura, Indy (2020). Therapeutic drug monitoring of commonly used anti-infective agents: A nationwide cross-sectional survey of Australian hospital practices. International Journal of Antimicrobial Agents, 56 (6) 106180, 106180. doi: 10.1016/j.ijantimicag.2020.106180

Therapeutic drug monitoring of commonly used anti-infective agents: A nationwide cross-sectional survey of Australian hospital practices

2020

Journal Article

Ceftriaxone dosing in patients admitted from the emergency department with sepsis

Heffernan, Aaron J., Curran, Rebecca A., Denny, Kerina J., Sime, Fekade B., Stanford, Claire L., McWhinney, Brett, Ungerer, Jacobus, Roberts, Jason A. and Lipman, Jeffrey (2020). Ceftriaxone dosing in patients admitted from the emergency department with sepsis. European Journal of Clinical Pharmacology, 77 (2), 207-214. doi: 10.1007/s00228-020-03001-z

Ceftriaxone dosing in patients admitted from the emergency department with sepsis

2020

Journal Article

The role of antibiotic pharmacokinetic studies performed post-licensing

Parker, Suzanne L., Abdul-Aziz, Mohd Hafiz and Roberts, Jason A. (2020). The role of antibiotic pharmacokinetic studies performed post-licensing. International Journal of Antimicrobial Agents, 56 (6) 106165, 106165. doi: 10.1016/j.ijantimicag.2020.106165

The role of antibiotic pharmacokinetic studies performed post-licensing

2020

Journal Article

Pharmacodynamic Analysis of Meropenem and Fosfomycin Combination Against Carbapenem-Resistant in Patients with Normal Renal Clearance: Can It Be a Treatment Option?

Mohd Sazlly Lim, Sazlyna, Heffernan, Aaron J., Roberts, Jason A. and Sime, Fekade B. (2020). Pharmacodynamic Analysis of Meropenem and Fosfomycin Combination Against Carbapenem-Resistant in Patients with Normal Renal Clearance: Can It Be a Treatment Option?. Microbial drug resistance (Larchmont, N.Y.), 27 (4) mdr.2020.0197, 546-552. doi: 10.1089/mdr.2020.0197

Pharmacodynamic Analysis of Meropenem and Fosfomycin Combination Against Carbapenem-Resistant in Patients with Normal Renal Clearance: Can It Be a Treatment Option?

2020

Journal Article

Effectiveness of therapeutic drug monitoring guided vancomycin dosing in adult patients receiving extra corporeal membrane oxygenation

Marella, Prashanti, Roberts, Jason, Hay, Karen and Shekar, Kiran (2020). Effectiveness of therapeutic drug monitoring guided vancomycin dosing in adult patients receiving extra corporeal membrane oxygenation. Antimicrobial Agents and Chemotherapy, 64 (9) e01179-20. doi: 10.1128/aac.01179-20

Effectiveness of therapeutic drug monitoring guided vancomycin dosing in adult patients receiving extra corporeal membrane oxygenation

2020

Journal Article

Physician drug prescribing preferences and availability for ventilation of patients with COVID-19

Coombes, Ian D., Dooley, Michael J., Townsend, Shane, Carmichael, Sinead, Poole, Susan G., Karamujic, Nermin, Richards, Brent, Ziegenfuss, Marc, Ankravs, Melissa J., Uren, Hailie, Roberts, Jason A. and Holley, Anthony (2020). Physician drug prescribing preferences and availability for ventilation of patients with COVID-19. Critical Care and Resuscitation, 22 (3), 271-274.

Physician drug prescribing preferences and availability for ventilation of patients with COVID-19

2020

Journal Article

Pharmacodynamic evaluation of intermittent versus extended and continuous infusions of piperacillin/tazobactam in a hollow-fibre infection model against Klebsiella pneumoniae

Sumi, Chandra Datta, Heffernan, Aaron J., Naicker, Saiyuri, Islam, Kamrul, Cottrell, Kyra, Wallis, Steven C., Lipman, Jeffrey, Harris, Patrick N. A., Sime, Fekade B. and Roberts, Jason A. (2020). Pharmacodynamic evaluation of intermittent versus extended and continuous infusions of piperacillin/tazobactam in a hollow-fibre infection model against Klebsiella pneumoniae. Journal of Antimicrobial Chemotherapy, 75 (9), 2633-2640. doi: 10.1093/jac/dkaa211

Pharmacodynamic evaluation of intermittent versus extended and continuous infusions of piperacillin/tazobactam in a hollow-fibre infection model against Klebsiella pneumoniae

2020

Journal Article

Ticarcillin and piperacillin adsorption on to polyethersulfone haemodiafilter membranes in an ex-vivo circuit

Economou, Caleb J. P., Ordoñez, Jennifer, Wallis, Steven C., Richards, Brent, McWhinney, Brett, Lipman, Jeffrey and Roberts, Jason A. (2020). Ticarcillin and piperacillin adsorption on to polyethersulfone haemodiafilter membranes in an ex-vivo circuit. International Journal of Antimicrobial Agents, 56 (3) 106058, 1-5. doi: 10.1016/j.ijantimicag.2020.106058

Ticarcillin and piperacillin adsorption on to polyethersulfone haemodiafilter membranes in an ex-vivo circuit

2020

Journal Article

What are the predictors for achieving therapeutic levetiracetam serum concentrations in adult neurological patients?

Cotta, Menino Osbert, Abdul-Aziz, Mohd Hafiz, Frey, Otto R., Sime, Fekade Bruck, Roberts, Jason A. and Roehr, Anka C. (2020). What are the predictors for achieving therapeutic levetiracetam serum concentrations in adult neurological patients?. Therapeutic Drug Monitoring, 42 (4), 626-630. doi: 10.1097/ftd.0000000000000731

What are the predictors for achieving therapeutic levetiracetam serum concentrations in adult neurological patients?

2020

Journal Article

How to design a study to evaluate therapeutic drug monitoring in infectious diseases?

Märtson, A. G., Sturkenboom, M. G. G., Stojanova, J., Cattaneo, D., Hope, W., Marriott, D., Patanwala, A. E., Peloquin, C. A., Wicha, S. G., van der Werf, T. S., Tängdén, T., Roberts, J. A., Neely, M. N. and Alffenaar, J. W. C. (2020). How to design a study to evaluate therapeutic drug monitoring in infectious diseases?. Clinical Microbiology and Infection, 26 (8), 1008-1016. doi: 10.1016/j.cmi.2020.03.008

How to design a study to evaluate therapeutic drug monitoring in infectious diseases?

2020

Journal Article

Pharmacokinetics/pharmacodynamics of antiviral agents used to treat SARS-CoV-2 and their potential interaction with drugs and other supportive measures: a comprehensive review by the PK/PD of anti-infectives study group of the European Society of Antimicrobial Agents

Zeitlinger, Markus, Koch, Birgit C. P., Bruggemann, Roger, De Cock, Pieter, Felton, Timothy, Hites, Maya, Le, Jennifer, Luque, Sonia, MacGowan, Alasdair P., Marriott, Deborah J. E., Muller, Anouk E., Nadrah, Kristina, Paterson, David L., Standing, Joseph F., Telles, João P., Wölfl-Duchek, Michael, Thy, Michael and Roberts, Jason A. (2020). Pharmacokinetics/pharmacodynamics of antiviral agents used to treat SARS-CoV-2 and their potential interaction with drugs and other supportive measures: a comprehensive review by the PK/PD of anti-infectives study group of the European Society of Antimicrobial Agents. Clinical Pharmacokinetics, 59 (10), 1195-1216. doi: 10.1007/s40262-020-00924-9

Pharmacokinetics/pharmacodynamics of antiviral agents used to treat SARS-CoV-2 and their potential interaction with drugs and other supportive measures: a comprehensive review by the PK/PD of anti-infectives study group of the European Society of Antimicrobial Agents

2020

Journal Article

Prolonged versus intermittent infusion of β-Lactam antibiotics: a systematic review and meta-regression of bacterial killing in preclinical infection models

Dhaese, Sofie, Heffernan, Aaron, Liu, David, Abdul-Aziz, Mohd Hafiz, Stove, Veronique, Tam, Vincent H., Lipman, Jeffrey, Roberts, Jason A. and De Waele, Jan J. (2020). Prolonged versus intermittent infusion of β-Lactam antibiotics: a systematic review and meta-regression of bacterial killing in preclinical infection models. Clinical Pharmacokinetics, 59 (10), 1237-1250. doi: 10.1007/s40262-020-00919-6

Prolonged versus intermittent infusion of β-Lactam antibiotics: a systematic review and meta-regression of bacterial killing in preclinical infection models

2020

Journal Article

The Australasian COVID-19 Trial (ASCOT) to assess clinical outcomes in hospitalised patients with SARS-CoV-2 infection (COVID-19) treated with lopinavir/ritonavir and/or hydroxychloroquine compared to standard of care: A structured summary of a study protocol for a randomised controlled trial

Denholm, Justin T., Davis, Joshua, Paterson, David, Roberts, Jason, Morpeth, Susan, Snelling, Thomas, Zentner, Dominica, Rees, Megan, O'Sullivan, Matthew, Price, David, Bowen, Asha, Tong, Steven Y. C., Davis, Joshua, Denholm, Justin, Tong, Steven, ASCOT Investigator Group, Rees, Megan, Paterson, David, Price, David, Morpeth, Susan, O'Sullivan, Matthew, Roberts, Jason, Snelling, Thomas, Anderson, Sue, McQuilton, Zoe, Venkatesh, Bala, Hammond, Naomi, Jha, Vivekanend, Burston, Victoria John ... Slow, Sandy (2020). The Australasian COVID-19 Trial (ASCOT) to assess clinical outcomes in hospitalised patients with SARS-CoV-2 infection (COVID-19) treated with lopinavir/ritonavir and/or hydroxychloroquine compared to standard of care: A structured summary of a study protocol for a randomised controlled trial. Trials, 21 (1) 646. doi: 10.1186/s13063-020-04576-9

The Australasian COVID-19 Trial (ASCOT) to assess clinical outcomes in hospitalised patients with SARS-CoV-2 infection (COVID-19) treated with lopinavir/ritonavir and/or hydroxychloroquine compared to standard of care: A structured summary of a study protocol for a randomised controlled trial

2020

Journal Article

Pharmacodynamic evaluation of plasma and epithelial lining fluid exposures of amikacin against in a dynamic hollow-fibre infection model

Heffernan, Aaron J., Sime, Fekade B., Sarovich, Derek S., Neely, Michael, Guerra-Valero, Yarmarly, Naicker, Saiyuri, Cottrell, Kyra, Harris, Patrick, Andrews, Katherine T., Ellwood, David, Wallis, Steven C., Lipman, Jeffrey, Grimwood, Keith and Roberts, Jason A. (2020). Pharmacodynamic evaluation of plasma and epithelial lining fluid exposures of amikacin against in a dynamic hollow-fibre infection model. Antimicrobial Agents and Chemotherapy, 64 (9) e00879-20. doi: 10.1128/aac.00879-20

Pharmacodynamic evaluation of plasma and epithelial lining fluid exposures of amikacin against in a dynamic hollow-fibre infection model