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2020

Journal Article

How to stimulate and facilitate early stage antibiotic discovery

Zuegg, Johannes, Hansford, Karl A., Elliott, Alysha G., Cooper, Matthew A. and Blaskovich, Mark A. T. (2020). How to stimulate and facilitate early stage antibiotic discovery. ACS Infectious Diseases, 6 (6), 1302-1304. doi: 10.1021/acsinfecdis.0c00163

How to stimulate and facilitate early stage antibiotic discovery

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2020

Journal Article

Metal complexes as a promising source for new antibiotics

Frei, Angelo, Zuegg, Johannes, Elliott, Alysha G., Baker, Murray V., Braese, Stefan, Brown, Christopher, Chen, Feng, Dowson, Christopher Gerard, Dujardin, Gilles, Jung, Nicole, King, A. Paden, Mansour, Ahmed Moustafa, Massi, Massimiliano, Moat, John, Mohamed, Heba A., Renfrew, Anna, Rutledge, Peter, Sadler, Peter J., Todd, Matthew Houghton, Willans, Charlotte E., Wilson, Justin Jeff, Cooper, Matthew Allister and Blaskovich, Mark (2020). Metal complexes as a promising source for new antibiotics. Chemical Science, 11 (10), 2627-2639. doi: 10.1039/c9sc06460e

Metal complexes as a promising source for new antibiotics

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2019

Journal Article

Fluoroquinolone-derived fluorescent probes for studies of bacterial penetration and efflux

Stone, M. Rhia L., Masi, Muriel, Phetsang, Wanida, Pagès, Jean-Marie, Cooper, Matthew A. and Blaskovich, Mark A. T. (2019). Fluoroquinolone-derived fluorescent probes for studies of bacterial penetration and efflux. MedChemComm, 10 (6), 901-906. doi: 10.1039/c9md00124g

Fluoroquinolone-derived fluorescent probes for studies of bacterial penetration and efflux

2019

Journal Article

The diminished antimicrobial pipeline

Blaskovich, Mark A.T. (2019). The diminished antimicrobial pipeline. Microbiology Australia, 40 (2), 92-96. doi: 10.1071/MA19025

The diminished antimicrobial pipeline

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2018

Journal Article

Can octapeptin antibiotics combat extensively drug-resistant (XDR) bacteria?

Blaskovich, Mark A. T., Pitt, Miranda E., Elliott, Alysha G. and Cooper, Matthew A. (2018). Can octapeptin antibiotics combat extensively drug-resistant (XDR) bacteria?. Expert Review of Anti-infective Therapy, 16 (6), 485-499. doi: 10.1080/14787210.2018.1483240

Can octapeptin antibiotics combat extensively drug-resistant (XDR) bacteria?

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2018

Journal Article

Fluorescent Antibiotics: New Research Tools to Fight Antibiotic Resistance

Stone, M Rhia L., Butler, Mark S., Phetsang, Wanida, Cooper, Matthew A. and Blaskovich, Mark A. T. (2018). Fluorescent Antibiotics: New Research Tools to Fight Antibiotic Resistance. Trends in Biotechnology, 36 (5), 523-536. doi: 10.1016/j.tibtech.2018.01.004

Fluorescent Antibiotics: New Research Tools to Fight Antibiotic Resistance

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2018

Journal Article

Structure, Function, and Biosynthetic Origin of Octapeptin Antibiotics Active against Extensively Drug-Resistant Gram-Negative Bacteria

Velkov, Tony, Gallardo-Godoy, Alejandra, Swarbrick, James D., Blaskovich, Mark A. T., Elliott, Alysha G., Han, Meiling, Thompson, Philip E., Roberts, Kade D., Huang, Johnny X., Becker, Bernd, Butler, Mark S., Lash, Lawrence H., Henriques, Sónia Troeira, Nation, Roger L., Sivanesan, Sivashangarie, Sani, Marc-Antoine, Separovic, Frances, Mertens, Haydyn, Bulach, Dieter, Seemann, Torsten, Owen, Jeremy, Li, Jian and Cooper, Matthew A. (2018). Structure, Function, and Biosynthetic Origin of Octapeptin Antibiotics Active against Extensively Drug-Resistant Gram-Negative Bacteria. Cell Chemical Biology, 25 (4), 380-391.e5. doi: 10.1016/j.chembiol.2018.01.005

Structure, Function, and Biosynthetic Origin of Octapeptin Antibiotics Active against Extensively Drug-Resistant Gram-Negative Bacteria

2018

Journal Article

Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria

Blaskovich, Mark A T, Hansford, Karl A., Gong, Yujing, Butler, Mark S., Muldoon, Craig, Huang, Johnny X., Ramu, Soumya, Silva, Alberto B., Cheng, Mu, Kavanagh, Angela M., Ziora, Zyta, Premraj, Rajaratnam, Lindahl, Fredrik, Bradford, Tanya A., Lee, June C., Karoli, Tomislav, Pelingon, Ruby, Edwards, David J., Amado, Maite, Elliott, Alysha G, Phetsang, Wanida, Daud, Noor Huda, Deecke, Johan E, Sidjabat, Hanna E, Ramaologa, Sefetogi, Zuegg, Johannes, Betley, Jason R, Beevers, Andrew P G, Smith, Richard A G ... Cooper, Matthew A. (2018). Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria. Nature Communications, 9 (1) 02123, 22. doi: 10.1038/s41467-017-02123-w

Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria

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2016

Journal Article

Unusual amino acids in medicinal chemistry

Blaskovich, Mark A. T. (2016). Unusual amino acids in medicinal chemistry. Journal of Medicinal Chemistry, 59 (24), 10807-10836. doi: 10.1021/acs.jmedchem.6b00319

Unusual amino acids in medicinal chemistry

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2016

Journal Article

Antibiotics in the clinical pipeline at the end of 2015

Butler, Mark S., Blaskovich, Mark A. T. and Cooper, Matthew A. (2016). Antibiotics in the clinical pipeline at the end of 2015. The Journal of Antibiotics, 70 (1), 1-22. doi: 10.1038/ja.2016.72

Antibiotics in the clinical pipeline at the end of 2015

2016

Journal Article

Fluorescent trimethoprim conjugate probes to assess drug accumulation in wild type and mutant Escherichia coli

Phetsang, Wanida, Pelingon, Ruby, Butler, Mark S., KC, Sanjaya, Pitt, Miranda, Kaeslin, Geraldine, Cooper, Matthew A. and Blaskovich, Mark A. T. (2016). Fluorescent trimethoprim conjugate probes to assess drug accumulation in wild type and mutant Escherichia coli. ACS Infectious Diseases, 2 (10), 688-701. doi: 10.1021/acsinfecdis.6b00080

Fluorescent trimethoprim conjugate probes to assess drug accumulation in wild type and mutant Escherichia coli

2026

Journal Article

High prevalence and co-existence of SHV and CTX-M genes in extensively drug-resistant (XDR) Gram-negative bacteria isolated from hospital settings in Faisalabad District, Pakistan

Abbas, Umair, Sajjad, Huma, Shaukat, Amir, Ahmad, Zaheer, Sattar, Azfar, Shehzad, Khurram, Blaskovich, Mark A. T., Da Silva Duarte, Tania, Zuegg, Johannes, Ali, Aamir and Sarwar, Yasra (2026). High prevalence and co-existence of SHV and CTX-M genes in extensively drug-resistant (XDR) Gram-negative bacteria isolated from hospital settings in Faisalabad District, Pakistan. Molecular Biology Reports, 53 (1) 494, 1-11. doi: 10.1007/s11033-026-11654-9

High prevalence and co-existence of SHV and CTX-M genes in extensively drug-resistant (XDR) Gram-negative bacteria isolated from hospital settings in Faisalabad District, Pakistan

2026

Journal Article

The biofilm matrix of uropathogenic Escherichia coli contributes to antimicrobial resistance by reducing molecular transport

Kulkarni, Rutuparna, Lian, Zheng Jie, Nhu, Nguyen Thi Khanh, Blaskovich, Mark A. T., Wohland, Thorsten and Schembri, Mark A. (2026). The biofilm matrix of uropathogenic Escherichia coli contributes to antimicrobial resistance by reducing molecular transport. npj Biofilms and Microbiomes. doi: 10.1038/s41522-026-01174-6

The biofilm matrix of uropathogenic Escherichia coli contributes to antimicrobial resistance by reducing molecular transport

2026

Journal Article

Rapid profiling of polymyxin B susceptibility in gram-negative bacteria with a novel polymyxin-derived fluorescent probe

Zhang, Bing, Phetsang, Wanida, Kc, Sanjaya, Butler, Mark S., Pelingon, Ruby, Elliott, Alysha G., Amado, Maite, Gallardo-Godoy, Alejandra, Cooper, Matthew A. and Blaskovich, Mark A. T. (2026). Rapid profiling of polymyxin B susceptibility in gram-negative bacteria with a novel polymyxin-derived fluorescent probe. Journal of Advanced Research. doi: 10.1016/j.jare.2026.01.019

Rapid profiling of polymyxin B susceptibility in gram-negative bacteria with a novel polymyxin-derived fluorescent probe

2026

Journal Article

Prophage and metabolic determinants of Staphylococcus aureus survival to vancomycin identified via TraDIS screening

Zborowsky, Sophia, Lapinska, Urszula, O'Neill, Paul A., Farbos, Audrey, Jeffries, Aaron R., Ba, Xiaoliang, Holmes, Mark A., Laabei, Maisem, Zhang, Bing, Blaskovich, Mark A. T., Grant, Andrew and Pagliara, Stefano (2026). Prophage and metabolic determinants of Staphylococcus aureus survival to vancomycin identified via TraDIS screening. mSystems e00734-26, e0073426-e0073426. doi: 10.1128/msystems.00734-26

Prophage and metabolic determinants of Staphylococcus aureus survival to vancomycin identified via TraDIS screening

2026

Journal Article

Fragment-based explainable AI for pathogen-selective antimicrobial drug design

Onawole, Abdulmujeeb T., Blaskovich, Mark A. T. and Zuegg, Johannes (2026). Fragment-based explainable AI for pathogen-selective antimicrobial drug design. ACS Infectious Diseases. doi: 10.1021/acsinfecdis.6c00325

Fragment-based explainable AI for pathogen-selective antimicrobial drug design

2026

Journal Article

Nanocellulose-directed ultrasmall copper nanoparticles for durable antimicrobial interfaces

Rajah, Divya, Athukoralalage, Sandya S. A., Zhu, Yanshan, Yegappan, Ramanathan, Chew, Keng, Blaskovich, Mark A. T. and Amiralian, Nasim (2026). Nanocellulose-directed ultrasmall copper nanoparticles for durable antimicrobial interfaces. Nanoscale. doi: 10.1039/d6nr02326f

Nanocellulose-directed ultrasmall copper nanoparticles for durable antimicrobial interfaces

2026

Journal Article

Newly identified antimicrobial activity of an 8-hydroxyquinoline-based ionophore against multidrug-resistant Enterococcus faecium and Staphylococcus aureus

Li, Gen, El-Deeb, Ibrahim M., Whyte, Hayden G., Blaskovich, Mark A. T., Walker, Mark J., von Itzstein, Mark and De Oliveira, David M. P. (2026). Newly identified antimicrobial activity of an 8-hydroxyquinoline-based ionophore against multidrug-resistant Enterococcus faecium and Staphylococcus aureus. Journal of Antimicrobial Chemotherapy, 81 (7). doi: 10.1093/jac/dkag186

Newly identified antimicrobial activity of an 8-hydroxyquinoline-based ionophore against multidrug-resistant Enterococcus faecium and Staphylococcus aureus

2026

Journal Article

High-throughput screening assays for novel antibacterial identification: current advances and future prospects

Floyd, Holly E. E., Novais de Paula, Michelle, Sen, Tanuka, Kavanagh, Angela M., Zuegg, Johannes and Blaskovich, Mark A. T. (2026). High-throughput screening assays for novel antibacterial identification: current advances and future prospects. Expert Opinion on Drug Discovery, 21 (7), 803-817. doi: 10.1080/17460441.2026.2679706

High-throughput screening assays for novel antibacterial identification: current advances and future prospects

2026

Journal Article

Pyrazolyl–pyridine ruthenium complexes: a new metallic line of defense against Acinetobacter baumannii

Joseph, M. Cassiem, Sookai, Sheldon, Nowakowska, Monika, Mphephu, Rotondwa, Kavanagh, Angela M., Zuegg, Johannes, Blaskovich, Mark A. T. and Swarts, Andrew J. (2026). Pyrazolyl–pyridine ruthenium complexes: a new metallic line of defense against Acinetobacter baumannii. ChemBioChem, 27 (9) e70371. doi: 10.1002/cbic.70371

Pyrazolyl–pyridine ruthenium complexes: a new metallic line of defense against Acinetobacter baumannii