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2022 Journal Article A lipoglycopeptide antibiotic for Gram-positive biofilm-related infectionsBlaskovich, Mark A.T., Hansford, Karl A., Butler, Mark S., Ramu, Soumya, Kavanagh, Angela M., Jarrad, Angie M., Prasetyoputri, Anggia, Pitt, Miranda E., Huang, Johnny X., Lindahl, Fredrik, Ziora, Zyta M., Bradford, Tanya, Muldoon, Craig, Rajaratnam, Premraj, Pelingon, Ruby, Edwards, David J., Zhang, Bing, Amado, Maite, Elliott, Alysha G., Zuegg, Johannes, Coin, Lachlan, Woischnig, Anne-Kathrin, Khanna, Nina, Breidenstein, Elena, Stincone, Anna, Mason, Clive, Khan, Nawaz, Cho, Hye-Kyung, Karau, Melissa J. ... Cooper, Matthew A. (2022). A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections. Science Translational Medicine, 14 (662) abj2381, 1-16. doi: 10.1126/scitranslmed.abj2381 |
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2022 Journal Article Investigations into the membrane activity of arenicin antimicrobial peptide AA139Edwards, Ingrid A., Henriques, Sónia T., Blaskovich, Mark A.T., Elliott, Alysha G. and Cooper, Matthew A. (2022). Investigations into the membrane activity of arenicin antimicrobial peptide AA139. Biochimica et Biophysica Acta - General Subjects, 1866 (8) 130156, 130156. doi: 10.1016/j.bbagen.2022.130156 |
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2022 Journal Article N-Alkyl-2-quinolonopyrones demonstrate antimicrobial activity against ESKAPE pathogens including Staphylococcus aureusMoynihan, Eoin, Mackey, Katrina, Blaskovich, Mark A. T., Reen, F. Jerry and McGlacken, Gerard (2022). N-Alkyl-2-quinolonopyrones demonstrate antimicrobial activity against ESKAPE pathogens including Staphylococcus aureus. ACS Medicinal Chemistry Letters, 13 (8), 1358-1362. doi: 10.1021/acsmedchemlett.2c00185 |
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2022 Journal Article Fast bacterial growth reduces antibiotic accumulation and efficacyŁapińska, Urszula, Voliotis, Margaritis, Lee, Ka Kiu, Campey, Adrian, Stone, Rhia M. L., Tuck, Brandon, Phetsang, Wanida, Zhang, Bing, Tsaneva-Atanasova, Krasimira, Blaskovich, Mark A. T. and Pagliara, Stefano (2022). Fast bacterial growth reduces antibiotic accumulation and efficacy. eLife, 11 e74062, 1-33. doi: 10.7554/ELIFE.74062 |
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2022 Journal Article Loss of β-ketoacyl acyl carrier protein synthase III activity restores multidrug-resistant escherichia coli sensitivity to previously ineffective antibioticsHong, Yaoqin, Qin, Jilong, Verderosa, Anthony D., Hawas, Sophia, Zhang, Bing, Blaskovich, Mark A. T., Cronan, John E. and Totsika, Makrina (2022). Loss of β-ketoacyl acyl carrier protein synthase III activity restores multidrug-resistant escherichia coli sensitivity to previously ineffective antibiotics. mSphere, 7 (3), e0011722. doi: 10.1128/msphere.00117-22 |
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2022 Journal Article Statistical evaluation of cow-dung derived activated biochar for phenol adsorption: adsorption isotherms, kinetics, and thermodynamic studiesJain, Marut, Khan, Sadaf Aiman, Sahoo, Abhisek, Dubey, Prashant, Pant, Kamal Kishore, Ziora, Zyta Maria and Blaskovich, Mark A.T. (2022). Statistical evaluation of cow-dung derived activated biochar for phenol adsorption: adsorption isotherms, kinetics, and thermodynamic studies. Bioresource Technology, 352 127030, 127030. doi: 10.1016/j.biortech.2022.127030 |
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2022 Journal Article Bridging informatics and medicinal inorganic chemistry: toward a database of metallodrugs and metallodrug candidatesMedina-Franco, José L., López-López, Edgar, Andrade, Emma, Ruiz-Azuara, Lena, Frei, Angelo, Guan, Davy, Zuegg, Johannes and Blaskovich, Mark A.T. (2022). Bridging informatics and medicinal inorganic chemistry: toward a database of metallodrugs and metallodrug candidates. Drug Discovery Today, 27 (5), 1420-1430. doi: 10.1016/j.drudis.2022.02.021 |
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2022 Journal Article Mechanisms underlying synergistic killing of Polymyxin B in combination with cannabidiol against Acinetobacter baumannii: a metabolomic studyHussein, Maytham, Allobawi, Rafah, Levou, Irini, Blaskovich, Mark A. T., Rao, Gauri G., Li, Jian and Velkov, Tony (2022). Mechanisms underlying synergistic killing of Polymyxin B in combination with cannabidiol against Acinetobacter baumannii: a metabolomic study. Pharmaceutics, 14 (4) 786, 786. doi: 10.3390/pharmaceutics14040786 |
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2022 Journal Article Amino alcohols as potential antibiotic and antifungal leadsBaker, Jennifer R., Cossar, Peter J., Blaskovich, Mark A. T., Elliott, Alysha G., Zuegg, Johannes, Cooper, Matthew A., Lewis, Peter J. and McCluskey, Adam (2022). Amino alcohols as potential antibiotic and antifungal leads. Molecules, 27 (7) 2050, 2050. doi: 10.3390/molecules27072050 |
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2022 Journal Article Nanomaterials: the new antimicrobial magic bulletNdayishimiye, John, Kumeria, Tushar, Popat, Amirali, Falconer, James Robert and Blaskovich, Mark A. T. (2022). Nanomaterials: the new antimicrobial magic bullet. ACS Infectious Diseases, 8 (4), 693-712. doi: 10.1021/acsinfecdis.1c00660 |
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2022 Journal Article Understanding the relationship between solubility and permeability of γ-cyclodextrin-based systems embedded with poorly aqueous soluble benznidazoleNdayishimiye, John, Kumeria, Tushar, Popat, Amirali, Blaskovich, Mark A.T. and Falconer, James Robert (2022). Understanding the relationship between solubility and permeability of γ-cyclodextrin-based systems embedded with poorly aqueous soluble benznidazole. International Journal of Pharmaceutics, 616 121487, 121487. doi: 10.1016/j.ijpharm.2022.121487 |
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2022 Journal Article Antimicrobial activity enhancers: towards smart delivery of antimicrobial agentsSkwarczynski, Mariusz, Bashiri, Sahra, Yuan, Ye, Ziora, Zyta M., Nabil, Osama, Masuda, Keita, Khongkow, Mattaka, Rimsueb, Natchanon, Cabral, Horacio, Ruktanonchai, Uracha, Blaskovich, Mark A. T. and Toth, Istvan (2022). Antimicrobial activity enhancers: towards smart delivery of antimicrobial agents. Antibiotics, 11 (3) 412, 412. doi: 10.3390/antibiotics11030412 |
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2022 Journal Article Booster for antibioticsBlaskovich, Mark (2022). Booster for antibiotics. Chemistry and Industry, 86 (3), 30-33. doi: 10.1002/cind.863_9.x |
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2022 Journal Article Featured article editorial: discovery of a tricyclic β-lactam active against carbapenem-resistant enterobacteralesBlaskovich, Mark (2022). Featured article editorial: discovery of a tricyclic β-lactam active against carbapenem-resistant enterobacterales. ACS Infectious Diseases, 8 (3) acsinfecdis.2c00088, 398-398. doi: 10.1021/acsinfecdis.2c00088 |
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2022 Journal Article Rescuing Tetracycline Class Antibiotics for the Treatment of Multidrug-Resistant Acinetobacter baumannii Pulmonary InfectionDe Oliveira, David M. P., Forde, Brian M., Phan, Minh-Duy, Steiner, Bernhard, Zhang, Bing, Zuegg, Johannes, El-deeb, Ibrahim M., Li, Gen, Keller, Nadia, Brouwer, Stephan, Harbison-Price, Nichaela, Cork, Amanda J., Bauer, Michelle J., Alquethamy, Saleh F., Beatson, Scott A., Roberts, Jason A., Paterson, David L., McEwan, Alastair G., Blaskovich, Mark A. T., Schembri, Mark A., McDevitt, Christopher A., von Itzstein, Mark and Walker, Mark J. (2022). Rescuing Tetracycline Class Antibiotics for the Treatment of Multidrug-Resistant Acinetobacter baumannii Pulmonary Infection. mBio, 13 (1) e03517, e0351721-1. doi: 10.1128/mbio.03517-21 |
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2021 Journal Article Loss of YhcB results in dysregulation of coordinated peptidoglycan, LPS and phospholipid synthesis during Escherichia coli cell growthGoodall, Emily C. A., Isom, Georgia L., Rooke, Jessica L., Pullela, Karthik, Icke, Christopher, Yang, Zihao, Boelter, Gabriela, Jones, Alun, Warner, Isabel, Da Costa, Rochelle, Zhang, Bing, Rae, James, Tan, Wee Boon, Winkle, Matthias, Delhaye, Antoine, Heinz, Eva, Collet, Jean-Francois, Cunningham, Adam F., Blaskovich, Mark A., Parton, Robert G., Cole, Jeff A., Banzhaf, Manuel, Chng, Shu-Sin, Vollmer, Waldemar, Bryant, Jack A. and Henderson, Ian R. (2021). Loss of YhcB results in dysregulation of coordinated peptidoglycan, LPS and phospholipid synthesis during Escherichia coli cell growth. PLoS Genetics, 17 (12) e1009586, 1-40. doi: 10.1371/journal.pgen.1009586 |
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2021 Journal Article Biostimulation of bacteria in liquid culture for identification of new antimicrobial compoundsMirzaee, Hooman, Ariens, Emily, Blaskovich, Mark A. T., Clark, Richard J. and Schenk, Peer M. (2021). Biostimulation of bacteria in liquid culture for identification of new antimicrobial compounds. Pharmaceuticals, 14 (12) 1232, 1232. doi: 10.3390/ph14121232 |
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2021 Journal Article CryoEM structure of the outer membrane secretin channel pIV from the f1 filamentous bacteriophageConners, Rebecca, McLaren, Mathew, Łapińska, Urszula, Sanders, Kelly, Stone, M. Rhia L., Blaskovich, Mark A. T., Pagliara, Stefano, Daum, Bertram, Rakonjac, Jasna and Gold, Vicki A. M. (2021). CryoEM structure of the outer membrane secretin channel pIV from the f1 filamentous bacteriophage. Nature Communications, 12 (1) 6316, 6316. doi: 10.1038/s41467-021-26610-3 |
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2021 Journal Article Instructive analysis of engineered carbon materials for potential application in water and wastewater treatmentJain, Marut, Khan, Sadaf Aiman, Pandey, Ashish, Pant, Kamal Kishore, Ziora, Zyta Maria and Blaskovich, Mark A.T. (2021). Instructive analysis of engineered carbon materials for potential application in water and wastewater treatment. Science of The Total Environment, 793 148583, 1-19. doi: 10.1016/j.scitotenv.2021.148583 |
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2021 Journal Article Design, synthesis and screening of a drug discovery library based on an Eremophila-derived serrulatane scaffoldZhang, Chen, Lum, Kah Yean, Taki, Aya C., Gasser, Robin B., Byrne, Joseph J., Wang, Tao, Blaskovich, Mark A.T., Register, Emery T., Montaner, Luis J., Tietjen, Ian and Davis, Rohan A. (2021). Design, synthesis and screening of a drug discovery library based on an Eremophila-derived serrulatane scaffold. Phytochemistry, 190 112887, 1-10. doi: 10.1016/j.phytochem.2021.112887 |
