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2022

Journal Article

Loss of β-ketoacyl acyl carrier protein synthase III activity restores multidrug-resistant escherichia coli sensitivity to previously ineffective antibiotics

Hong, Yaoqin, Qin, Jilong, Verderosa, Anthony D., Hawas, Sophia, Zhang, Bing, Blaskovich, Mark A. T., Cronan, John E. and Totsika, Makrina (2022). Loss of β-ketoacyl acyl carrier protein synthase III activity restores multidrug-resistant escherichia coli sensitivity to previously ineffective antibiotics. mSphere, 7 (3), e0011722. doi: 10.1128/msphere.00117-22

Loss of β-ketoacyl acyl carrier protein synthase III activity restores multidrug-resistant escherichia coli sensitivity to previously ineffective antibiotics

2022

Journal Article

Statistical evaluation of cow-dung derived activated biochar for phenol adsorption: adsorption isotherms, kinetics, and thermodynamic studies

Jain, Marut, Khan, Sadaf Aiman, Sahoo, Abhisek, Dubey, Prashant, Pant, Kamal Kishore, Ziora, Zyta Maria and Blaskovich, Mark A.T. (2022). Statistical evaluation of cow-dung derived activated biochar for phenol adsorption: adsorption isotherms, kinetics, and thermodynamic studies. Bioresource Technology, 352 127030, 127030. doi: 10.1016/j.biortech.2022.127030

Statistical evaluation of cow-dung derived activated biochar for phenol adsorption: adsorption isotherms, kinetics, and thermodynamic studies

2022

Journal Article

Bridging informatics and medicinal inorganic chemistry: toward a database of metallodrugs and metallodrug candidates

Medina-Franco, José L., López-López, Edgar, Andrade, Emma, Ruiz-Azuara, Lena, Frei, Angelo, Guan, Davy, Zuegg, Johannes and Blaskovich, Mark A.T. (2022). Bridging informatics and medicinal inorganic chemistry: toward a database of metallodrugs and metallodrug candidates. Drug Discovery Today, 27 (5), 1420-1430. doi: 10.1016/j.drudis.2022.02.021

Bridging informatics and medicinal inorganic chemistry: toward a database of metallodrugs and metallodrug candidates

2022

Journal Article

Mechanisms underlying synergistic killing of Polymyxin B in combination with cannabidiol against Acinetobacter baumannii: a metabolomic study

Hussein, Maytham, Allobawi, Rafah, Levou, Irini, Blaskovich, Mark A. T., Rao, Gauri G., Li, Jian and Velkov, Tony (2022). Mechanisms underlying synergistic killing of Polymyxin B in combination with cannabidiol against Acinetobacter baumannii: a metabolomic study. Pharmaceutics, 14 (4) 786, 786. doi: 10.3390/pharmaceutics14040786

Mechanisms underlying synergistic killing of Polymyxin B in combination with cannabidiol against Acinetobacter baumannii: a metabolomic study

2022

Journal Article

Amino alcohols as potential antibiotic and antifungal leads

Baker, Jennifer R., Cossar, Peter J., Blaskovich, Mark A. T., Elliott, Alysha G., Zuegg, Johannes, Cooper, Matthew A., Lewis, Peter J. and McCluskey, Adam (2022). Amino alcohols as potential antibiotic and antifungal leads. Molecules, 27 (7) 2050, 2050. doi: 10.3390/molecules27072050

Amino alcohols as potential antibiotic and antifungal leads

2022

Journal Article

Nanomaterials: the new antimicrobial magic bullet

Ndayishimiye, John, Kumeria, Tushar, Popat, Amirali, Falconer, James Robert and Blaskovich, Mark A. T. (2022). Nanomaterials: the new antimicrobial magic bullet. ACS Infectious Diseases, 8 (4), 693-712. doi: 10.1021/acsinfecdis.1c00660

Nanomaterials: the new antimicrobial magic bullet

2022

Journal Article

Understanding the relationship between solubility and permeability of γ-cyclodextrin-based systems embedded with poorly aqueous soluble benznidazole

Ndayishimiye, John, Kumeria, Tushar, Popat, Amirali, Blaskovich, Mark A.T. and Falconer, James Robert (2022). Understanding the relationship between solubility and permeability of γ-cyclodextrin-based systems embedded with poorly aqueous soluble benznidazole. International Journal of Pharmaceutics, 616 121487, 121487. doi: 10.1016/j.ijpharm.2022.121487

Understanding the relationship between solubility and permeability of γ-cyclodextrin-based systems embedded with poorly aqueous soluble benznidazole

2022

Journal Article

Antimicrobial activity enhancers: towards smart delivery of antimicrobial agents

Skwarczynski, Mariusz, Bashiri, Sahra, Yuan, Ye, Ziora, Zyta M., Nabil, Osama, Masuda, Keita, Khongkow, Mattaka, Rimsueb, Natchanon, Cabral, Horacio, Ruktanonchai, Uracha, Blaskovich, Mark A. T. and Toth, Istvan (2022). Antimicrobial activity enhancers: towards smart delivery of antimicrobial agents. Antibiotics, 11 (3) 412, 412. doi: 10.3390/antibiotics11030412

Antimicrobial activity enhancers: towards smart delivery of antimicrobial agents

2022

Journal Article

Booster for antibiotics

Blaskovich, Mark (2022). Booster for antibiotics. Chemistry and Industry, 86 (3), 30-33. doi: 10.1002/cind.863_9.x

Booster for antibiotics

2022

Journal Article

Featured article editorial: discovery of a tricyclic β-lactam active against carbapenem-resistant enterobacterales

Blaskovich, Mark (2022). Featured article editorial: discovery of a tricyclic β-lactam active against carbapenem-resistant enterobacterales. ACS Infectious Diseases, 8 (3) acsinfecdis.2c00088, 398-398. doi: 10.1021/acsinfecdis.2c00088

Featured article editorial: discovery of a tricyclic β-lactam active against carbapenem-resistant enterobacterales

2022

Journal Article

Rescuing Tetracycline Class Antibiotics for the Treatment of Multidrug-Resistant Acinetobacter baumannii Pulmonary Infection

De Oliveira, David M. P., Forde, Brian M., Phan, Minh-Duy, Steiner, Bernhard, Zhang, Bing, Zuegg, Johannes, El-deeb, Ibrahim M., Li, Gen, Keller, Nadia, Brouwer, Stephan, Harbison-Price, Nichaela, Cork, Amanda J., Bauer, Michelle J., Alquethamy, Saleh F., Beatson, Scott A., Roberts, Jason A., Paterson, David L., McEwan, Alastair G., Blaskovich, Mark A. T., Schembri, Mark A., McDevitt, Christopher A., von Itzstein, Mark and Walker, Mark J. (2022). Rescuing Tetracycline Class Antibiotics for the Treatment of Multidrug-Resistant Acinetobacter baumannii Pulmonary Infection. mBio, 13 (1) e03517, e0351721. doi: 10.1128/mbio.03517-21

Rescuing Tetracycline Class Antibiotics for the Treatment of Multidrug-Resistant Acinetobacter baumannii Pulmonary Infection

2021

Journal Article

Loss of YhcB results in dysregulation of coordinated peptidoglycan, LPS and phospholipid synthesis during Escherichia coli cell growth

Goodall, Emily C. A., Isom, Georgia L., Rooke, Jessica L., Pullela, Karthik, Icke, Christopher, Yang, Zihao, Boelter, Gabriela, Jones, Alun, Warner, Isabel, Da Costa, Rochelle, Zhang, Bing, Rae, James, Tan, Wee Boon, Winkle, Matthias, Delhaye, Antoine, Heinz, Eva, Collet, Jean-Francois, Cunningham, Adam F., Blaskovich, Mark A., Parton, Robert G., Cole, Jeff A., Banzhaf, Manuel, Chng, Shu-Sin, Vollmer, Waldemar, Bryant, Jack A. and Henderson, Ian R. (2021). Loss of YhcB results in dysregulation of coordinated peptidoglycan, LPS and phospholipid synthesis during Escherichia coli cell growth. PLoS Genetics, 17 (12) e1009586, 1-40. doi: 10.1371/journal.pgen.1009586

Loss of YhcB results in dysregulation of coordinated peptidoglycan, LPS and phospholipid synthesis during Escherichia coli cell growth

2021

Journal Article

Biostimulation of bacteria in liquid culture for identification of new antimicrobial compounds

Mirzaee, Hooman, Ariens, Emily, Blaskovich, Mark A. T., Clark, Richard J. and Schenk, Peer M. (2021). Biostimulation of bacteria in liquid culture for identification of new antimicrobial compounds. Pharmaceuticals, 14 (12) 1232, 1232. doi: 10.3390/ph14121232

Biostimulation of bacteria in liquid culture for identification of new antimicrobial compounds

2021

Journal Article

CryoEM structure of the outer membrane secretin channel pIV from the f1 filamentous bacteriophage

Conners, Rebecca, McLaren, Mathew, Łapińska, Urszula, Sanders, Kelly, Stone, M. Rhia L., Blaskovich, Mark A. T., Pagliara, Stefano, Daum, Bertram, Rakonjac, Jasna and Gold, Vicki A. M. (2021). CryoEM structure of the outer membrane secretin channel pIV from the f1 filamentous bacteriophage. Nature Communications, 12 (1) 6316, 6316. doi: 10.1038/s41467-021-26610-3

CryoEM structure of the outer membrane secretin channel pIV from the f1 filamentous bacteriophage

2021

Journal Article

Instructive analysis of engineered carbon materials for potential application in water and wastewater treatment

Jain, Marut, Khan, Sadaf Aiman, Pandey, Ashish, Pant, Kamal Kishore, Ziora, Zyta Maria and Blaskovich, Mark A.T. (2021). Instructive analysis of engineered carbon materials for potential application in water and wastewater treatment. Science of The Total Environment, 793 148583, 1-19. doi: 10.1016/j.scitotenv.2021.148583

Instructive analysis of engineered carbon materials for potential application in water and wastewater treatment

2021

Journal Article

Design, synthesis and screening of a drug discovery library based on an Eremophila-derived serrulatane scaffold

Zhang, Chen, Lum, Kah Yean, Taki, Aya C., Gasser, Robin B., Byrne, Joseph J., Wang, Tao, Blaskovich, Mark A.T., Register, Emery T., Montaner, Luis J., Tietjen, Ian and Davis, Rohan A. (2021). Design, synthesis and screening of a drug discovery library based on an Eremophila-derived serrulatane scaffold. Phytochemistry, 190 112887, 1-10. doi: 10.1016/j.phytochem.2021.112887

Design, synthesis and screening of a drug discovery library based on an Eremophila-derived serrulatane scaffold

2021

Journal Article

Serum complement activation by C4BP-IgM fusion protein can restore susceptibility to antibiotics in Neisseria gonorrhoeae

Bettoni, Serena, Maziarz, Karolina, Stone, M. Rhia L., Blaskovich, Mark A. T., Potempa, Jan, Bazzo, Maria Luiza, Unemo, Magnus, Ram, Sanjay and Blom, Anna M. (2021). Serum complement activation by C4BP-IgM fusion protein can restore susceptibility to antibiotics in Neisseria gonorrhoeae. Frontiers in Immunology, 12 726801, 1-15. doi: 10.3389/fimmu.2021.726801

Serum complement activation by C4BP-IgM fusion protein can restore susceptibility to antibiotics in Neisseria gonorrhoeae

2021

Journal Article

Mesoporous silica nanoparticles improve oral delivery of antitubercular bicyclic nitroimidazoles

Ang, Chee Wei, Tan, Lendl, Qu, Zhi, West, Nicholas P., Cooper, Matthew A., Popat, Amirali and Blaskovich, Mark A.T. (2021). Mesoporous silica nanoparticles improve oral delivery of antitubercular bicyclic nitroimidazoles. ACS Biomaterials Science and Engineering, 8 (10) acsbiomaterials.1c00807, 4196-4206. doi: 10.1021/acsbiomaterials.1c00807

Mesoporous silica nanoparticles improve oral delivery of antitubercular bicyclic nitroimidazoles

2021

Journal Article

Antibiotic alternatives special issue

Blaskovich, Mark A. T. (2021). Antibiotic alternatives special issue. ACS Infectious Diseases, 7 (8), 2025-2026. doi: 10.1021/acsinfecdis.1c00388

Antibiotic alternatives special issue

2021

Journal Article

Targeted protein degradation: the new frontier of antimicrobial discovery?

Powell, Matthew, Blaskovich, Mark A. T. and Hansford, Karl A. (2021). Targeted protein degradation: the new frontier of antimicrobial discovery?. ACS Infectious Diseases, 7 (8) acsinfecdis.1c00203, 2050-2067. doi: 10.1021/acsinfecdis.1c00203

Targeted protein degradation: the new frontier of antimicrobial discovery?