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2019

Book Chapter

Clinical Pharmacy Considerations in ICU

Jamal, Janattul-Ain, Abdul-Aziz, Mohd-Hafiz, Levkovich, Bianca and Roberts, Jason A. (2019). Clinical Pharmacy Considerations in ICU. Encyclopedia of Pharmacy Practice and Clinical Pharmacy. (pp. 849-865) Amsterdam, Netherlands: Elsevier. doi: 10.1016/B978-0-12-812735-3.00576-8

Clinical Pharmacy Considerations in ICU

2018

Journal Article

New paradigm for rapid achievement of appropriate therapy in special populations: coupling antibiotic dose optimisation rapid microbiological methods

Abdul-Aziz, Mohd H., Driver, Elicia, Lipman, Jeffrey and Roberts, Jason A. (2018). New paradigm for rapid achievement of appropriate therapy in special populations: coupling antibiotic dose optimisation rapid microbiological methods. Expert Opinion on Drug Metabolism and Toxicology, 14 (7), 1-16. doi: 10.1080/17425255.2018.1484452

New paradigm for rapid achievement of appropriate therapy in special populations: coupling antibiotic dose optimisation rapid microbiological methods

2018

Journal Article

Optimising drug dosing in patients receiving extracorporeal membrane oxygenation

Cheng, Vesa, Abdul-Aziz, Mohd-Hafiz, Roberts, Jason A. and Shekar, Kiran (2018). Optimising drug dosing in patients receiving extracorporeal membrane oxygenation. Journal of Thoracic Disease, 10 (Suppl 5), S629-S641. doi: 10.21037/jtd.2017.09.154

Optimising drug dosing in patients receiving extracorporeal membrane oxygenation

2018

Journal Article

Prolonged Infusion Piperacillin-Tazobactam Decreases Mortality and Improves Outcomes in Severely Ill Patients: Results of a Systematic Review and Meta-Analysis

Rhodes, Nathaniel J., Liu, Jiajun, O'Donnell, J. Nicholas, Dulhunty, Joel M., Abdul-Aziz, Mohd H., Berko, Patsy Y., Nadler, Barbara, Lipman, Jeffery and Roberts, Jason A. (2018). Prolonged Infusion Piperacillin-Tazobactam Decreases Mortality and Improves Outcomes in Severely Ill Patients: Results of a Systematic Review and Meta-Analysis. Critical Care Medicine, 46 (2), 236-243. doi: 10.1097/CCM.0000000000002836

Prolonged Infusion Piperacillin-Tazobactam Decreases Mortality and Improves Outcomes in Severely Ill Patients: Results of a Systematic Review and Meta-Analysis

2018

Book Chapter

Antibiotic dosing during extracorporeal membrane oxygenation

Abdul-Aziz, M. H., Shekar, Kiran and Roberts, Jason A. (2018). Antibiotic dosing during extracorporeal membrane oxygenation. Antibiotic Pharmacokinetic/Pharmacodynamic Considerations in the Critically Ill. (pp. 151-171) edited by Andrew A. Udy, Jason A. Roberts and Jeffrey Lipman. Gateway East, Singapore: Springer . doi: 10.1007/978-981-10-5336-8_8

Antibiotic dosing during extracorporeal membrane oxygenation

2018

Conference Publication

Does dosing of ceftriaxone in critically ill patients on ECMO need to change? A pharmacokinetics study

Cheng, V., Shekar, K., Abdul-Aziz, M. H., Buscher, H., Corley, A., Diehl, A., Gilder, A., Jarrett, P., Lye, I., McGuinness, S., Parke, R., Pellegrino, V., Reynolds, C., Wallis, S. C., Welch, S., Zacharias, D., Fraser, J. F. and Roberts, J. A. (2018). Does dosing of ceftriaxone in critically ill patients on ECMO need to change? A pharmacokinetics study. European Society of Intensive Care Medicine Annual Congress, Paris, France, 20-24 October 2018. Heidelberg, Germany: Springer.

Does dosing of ceftriaxone in critically ill patients on ECMO need to change? A pharmacokinetics study

2018

Conference Publication

Does dosing of piperacillin-tazobactam in critically ill patients on ECMO need to change? A pharmacokinetics study

Cheng, V., Shekar, K., Abdul-Aziz, M.H., Buscher, H., Corley, A., Diehl, A., Gilder, E., Jarrett, P., Lye, I., McGuinness, S., Parke, R., Pellegrino, V., Reynolds, C., Wallis, S. C., Welch, S., Zacharias, D., Fraser, J. F. and Roberts, J. A. (2018). Does dosing of piperacillin-tazobactam in critically ill patients on ECMO need to change? A pharmacokinetics study. European Society of Intensive Care Medicine Annual Congress, Paris, France, 20-24 October 2018. Heidelberg, Germany: Springer.

Does dosing of piperacillin-tazobactam in critically ill patients on ECMO need to change? A pharmacokinetics study

2017

Journal Article

Identifying "at-risk" patients for sub-optimal beta-lactam exposure in critically ill patients with severe infections

Abdul-Aziz, Mohd H., Lipman, Jeffrey and Roberts, Jason A. (2017). Identifying "at-risk" patients for sub-optimal beta-lactam exposure in critically ill patients with severe infections. Critical Care, 21 (1) 283, 1-3. doi: 10.1186/s13054-017-1871-2

Identifying "at-risk" patients for sub-optimal beta-lactam exposure in critically ill patients with severe infections

2017

Journal Article

Incremental research approach to describing the pharmacokinetics of ciprofloxacin during extracorporeal membrane oxygenation

Sinnah, Fabrice, Shekar, Kiran, Abdul-Aziz, Mohd H, Buscher, Hergen, Diab, Sara D., Fisquet, Stephanie, Fung, Yoke L., McDonald, Charles I., Reynolds, Claire, Rudham, Sam, Wallis, Steven C., Welch, Susan, Xie, Jiao, Fraser, John F., Roberts, Jason A. and ASAP ECMO investigators (2017). Incremental research approach to describing the pharmacokinetics of ciprofloxacin during extracorporeal membrane oxygenation. Critical Care and Resuscitation, 19 (Suppl 1), 8-14.

Incremental research approach to describing the pharmacokinetics of ciprofloxacin during extracorporeal membrane oxygenation

2017

Journal Article

Pharmacokinetic/pharmacodynamics-optimized antimicrobial therapy in patients with hospital-acquired pneumonia/ventilator-associated pneumonia

Sulaiman, Helmi, Abdul-Aziz, Mohd H. and Roberts, Jason A. (2017). Pharmacokinetic/pharmacodynamics-optimized antimicrobial therapy in patients with hospital-acquired pneumonia/ventilator-associated pneumonia. Seminars in Respiratory and Critical Care Medicine, 38 (3) 01275, 271-286. doi: 10.1055/s-0037-1602716

Pharmacokinetic/pharmacodynamics-optimized antimicrobial therapy in patients with hospital-acquired pneumonia/ventilator-associated pneumonia

2016

Journal Article

Antibiotic dosing for multidrug-resistant pathogen pneumonia

Abdul-Aziz, Mohd. H., Lipman, Jeffrey and Roberts, Jason A. (2016). Antibiotic dosing for multidrug-resistant pathogen pneumonia. Current Opinion in Infectious Diseases, 30 (2), 231-239. doi: 10.1097/QCO.0000000000000348

Antibiotic dosing for multidrug-resistant pathogen pneumonia

2016

Journal Article

Prolonged administration of beta-lactam antibiotics - a comprehensive review and critical appraisal

Osthoff, Michael, Siegemund, Martin, Balestra, Gianmarco, Abdul-Aziz, Mohd H. and Roberts, Jason A. (2016). Prolonged administration of beta-lactam antibiotics - a comprehensive review and critical appraisal. Swiss Medical Weekly, 146 (4142) w14368, w14368-w14368. doi: 10.4414/smw.2016.14368

Prolonged administration of beta-lactam antibiotics - a comprehensive review and critical appraisal

2016

Journal Article

Continuous versus intermittent β-lactam infusion in severe sepsis: a meta-analysis of individual patient data from randomized trials

Roberts, Jason A., Abdul-Aziz, Mohd-Hafiz, Davis, Joshua S., Dulhunty, Joel M., Cotta, Menino O., Myburgh, John, Bellomo, Rinaldo and Lipman, Jeffrey (2016). Continuous versus intermittent β-lactam infusion in severe sepsis: a meta-analysis of individual patient data from randomized trials. American Journal of Respiratory and Critical Care Medicine, 194 (6), 681-691. doi: 10.1164/rccm.201601-0024OC

Continuous versus intermittent β-lactam infusion in severe sepsis: a meta-analysis of individual patient data from randomized trials

2016

Other Outputs

Optimizing beta-lactam antibiotic dosing in critically ill patients: Prolonged infusion versus intermittent bolus administration

Abdul Aziz, Mohd H. (2016). Optimizing beta-lactam antibiotic dosing in critically ill patients: Prolonged infusion versus intermittent bolus administration. PhD Thesis, School of Medicine, The University of Queensland. doi: 10.14264/uql.2016.450

Optimizing beta-lactam antibiotic dosing in critically ill patients: Prolonged infusion versus intermittent bolus administration

2016

Journal Article

What is the effect of obesity on piperacillin and meropenem trough concentrations in critically ill patients?

Alobaid, Abdulaziz S., Brinkmann, Alexander, Frey, Otto R., Roehr, Anka C., Luque, Sonia, Grau, Santiago, Wong, Gloria, Abdul-Aziz, Mohd-Hafiz, Roberts, Michael S., Lipman, Jeffrey and Roberts, Jason A. (2016). What is the effect of obesity on piperacillin and meropenem trough concentrations in critically ill patients?. Journal of Antimicrobial Chemotherapy, 71 (3) dkv412, 696-702. doi: 10.1093/jac/dkv412

What is the effect of obesity on piperacillin and meropenem trough concentrations in critically ill patients?

2016

Journal Article

Impact of the MIC of piperacillin/tazobactam on the outcome for patients with bacteraemia due to Enterobacteriaceae: the Bacteraemia-MIC project

Delgado-Valverde, Mercedes, Torres, Eva, Valiente-Mendez, Adoracion, Almirante, Benito, Gomez-Zorrilla, Silvia, Borrell, Nuria, Corzo, Juan E., Gurgui, Mercedes, Almela, Manuel, Garcia-Alvarez, Lara, Fontecoba-Sanchez, Maria Crus, Martinez-Martinez, Luis, Canton, Rafael, Praena, Julia, Causse, Manuel, Gutierrez-Gutierrez, Belen, Roberts, Jason A., Farkas, Andras, Pascual, Alvaro, Rodriguez-Bano, Jesus, de Cueto, Marina, Planes Reig, Ana Maria, Quintano, Fe Tubau, Pena, Carmen, Galan Otalora, M. Elvira, Alegria, Carlos Ruiz de, Morosini, M. Isabel, Lepe, Jose Antonio, Cisneros, Jose Miguel ... Abdul-Aziz, Mohd-Hafiz (2016). Impact of the MIC of piperacillin/tazobactam on the outcome for patients with bacteraemia due to Enterobacteriaceae: the Bacteraemia-MIC project. Journal of Antimicrobial Chemotherapy, 71 (2) dkv362, 521-530. doi: 10.1093/jac/dkv362

Impact of the MIC of piperacillin/tazobactam on the outcome for patients with bacteraemia due to Enterobacteriaceae: the Bacteraemia-MIC project

2016

Journal Article

Population pharmacokinetics of doripenem in critically ill patients with sepsis in a Malaysian intensive care unit

Abdul-Aziz, Mohd H., Abd Rahman, Azrin N., Mat-Nor, Mohd-Basri, Sulaiman, Helmi, Wallis, Steven C., Lipman, Jeffrey, Roberts, Jason A. and Staatz, Christine E. (2016). Population pharmacokinetics of doripenem in critically ill patients with sepsis in a Malaysian intensive care unit. Antimicrobial Agents and Chemotherapy, 60 (1), 206-214. doi: 10.1128/AAC.01543-15

Population pharmacokinetics of doripenem in critically ill patients with sepsis in a Malaysian intensive care unit

2016

Journal Article

Is prolonged infusion of piperacillin/tazobactam and meropenem in critically ill patients associated with improved pharmacokinetic/pharmacodynamic and patient outcomes? An observation from the Defining Antibiotic Levels in Intensive care unit patients (DALI) cohort

Abdul-Aziz, Mohd H., Lipman, Jeffrey, Akova, Murat, Bassetti, Matteo, De Waele, Jan J., Dimopoulos, George, Dulhunty, Joel, Kaukonen, Kirsi-Maija, Koulenti, Despoina, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C., Roberts, Jason A., Paul, Sanjoy, Ribas, Antonio Margarit, De Crop, Luc, Spapen, Herbert, Wauters, Joost, Dugernier, Thierry, Jorens, Philippe, Dapper, Ilse, De Backer, Daniel, Taccone, Fabio S., Ruano, Laura, Afonso, Elsa, Alvarez-Lerma, Francisco ... Ozveren, Arife (2016). Is prolonged infusion of piperacillin/tazobactam and meropenem in critically ill patients associated with improved pharmacokinetic/pharmacodynamic and patient outcomes? An observation from the Defining Antibiotic Levels in Intensive care unit patients (DALI) cohort. Journal of Antimicrobial Chemotherapy, 71 (1), 196-207. doi: 10.1093/jac/dkv288

Is prolonged infusion of piperacillin/tazobactam and meropenem in critically ill patients associated with improved pharmacokinetic/pharmacodynamic and patient outcomes? An observation from the Defining Antibiotic Levels in Intensive care unit patients (DALI) cohort

2015

Journal Article

Applying Pharmacokinetic/Pharmacodynamic Principles in Critically Ill Patients: Optimizing Efficacy and Reducing Resistance Development

Abdul-Aziz, Mohd H., Lipman, Jeffrey, Mouton, Johan W., Hope, William W. and Roberts, Jason A. (2015). Applying Pharmacokinetic/Pharmacodynamic Principles in Critically Ill Patients: Optimizing Efficacy and Reducing Resistance Development. Seminars in Respiratory and Critical Care Medicine, 36 (1), 136-153. doi: 10.1055/s-0034-1398490

Applying Pharmacokinetic/Pharmacodynamic Principles in Critically Ill Patients: Optimizing Efficacy and Reducing Resistance Development

2015

Conference Publication

The BLISS Study: Beta-Lactam Infusion in Severe Sepsis- Randomised controlled trial of continuous versus intermittent beta-lactam infusion in critically ill patients with severe sepsis in a Malaysian ICU setting

Abdul-Aziz, M. H., Sulaiman, H., Mat-Nor, M., Rai, V., Wong, K., Hasan, M., Wallis, S., Lipman, J., Staatz, C. E. and Roberts, J. (2015). The BLISS Study: Beta-Lactam Infusion in Severe Sepsis- Randomised controlled trial of continuous versus intermittent beta-lactam infusion in critically ill patients with severe sepsis in a Malaysian ICU setting. Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), San Diego, CA United States, 17-21 September 2015.

The BLISS Study: Beta-Lactam Infusion in Severe Sepsis- Randomised controlled trial of continuous versus intermittent beta-lactam infusion in critically ill patients with severe sepsis in a Malaysian ICU setting